CN105147770A - Composition having body odor removal function and preparation method and application thereof - Google Patents

Composition having body odor removal function and preparation method and application thereof Download PDF

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Publication number
CN105147770A
CN105147770A CN201510543025.0A CN201510543025A CN105147770A CN 105147770 A CN105147770 A CN 105147770A CN 201510543025 A CN201510543025 A CN 201510543025A CN 105147770 A CN105147770 A CN 105147770A
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CN
China
Prior art keywords
bromhidrosis
function
except
compositions
preparation
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Pending
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CN201510543025.0A
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Chinese (zh)
Inventor
杨洋
彭佩
陈军
杨成雄
顾薇
施红
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hubei Jingchu Science And Technology Development Co Ltd
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Hubei Jingchu Science And Technology Development Co Ltd
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Priority to CN201510543025.0A priority Critical patent/CN105147770A/en
Publication of CN105147770A publication Critical patent/CN105147770A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a composition having a body odor removal function and a preparation method and application thereof. The composition comprises, by weight, 0.2-8 parts of tannic acid, 0.1-10 parts of hamamelitannin, 0.2-8 parts of aluminum chloride, 0.5-10 parts of ethyl alcohol, 0.5-5 parts of salicylic acid, 1-30 parts of distilled water, 0.05-2 parts of a flavoring agent. The preparation method includes: 1, weighing the tannic acid, hamamelitannin, aluminum chloride, ethyl alcohol, salicylic acid, distilled water and flavoring agent according to the above ratios; 2, mixing the components well. The composition is high in safety, free of toxic and side effects and low stimulation to skin, is effective in killing germs causing body odor, and accordingly is applicable to the preparation of medicaments for treating body odor and applicable to treating body door, with short medication time, high curative rate and rarity of reoccurrence. The preparation method of the composition has a simple technical process and is convenient to operate.

Description

A kind of tool removes composition and method of making the same and the purposes of bromhidrosis function
Technical field
The present invention relates to technical field of medicine, be specifically related to the compositions of a kind of tool except bromhidrosis function, relate to the preparation method of a kind of tool except the compositions of bromhidrosis function simultaneously, also relate to the purposes of a kind of tool except the compositions of bromhidrosis function.
Background technology
Fetid sweat another name bromhidrosis, refers to that the perspiration of secretion has the stink of special stink or perspiration generation after decomposing.Bromhidrosis Producing reason produces unsaturated fatty acid (having off-odor) because the secretions of antibacterial and apocrine gland is had an effect.The method of present treatment bromhidrosis is a lot, selection laser the most conventional or operative treatment.There is the problem of easily recurrence in laser therapy, operative treatment can leave cicatrix clearly, wears the clothes summer few, can affect the attractive in appearance of oxter.Therefore, drug application solves hyperhidrosis, fundamentally treats the emphasis that bromhidrosis becomes Recent study.And the medicine for the treatment of now bromhidrosis is divided into Chinese medicine and Western medicine usually, Chinese medicine is by damp and hot in body being dispelled, and its heat loose eliminates bromhidrosis, but to have administration time long for it, and applicable is limited in scope, not accept by everybody; Western medicine is generally external, mainly eliminate taste by covering bromhidrosis abnormal smells from the patient, but can not treat it at all, and life-time service has certain side effect, Western medicine in general DeGrain for oral administration, and has certain side effect.
Summary of the invention
For solving above-mentioned prior art Problems existing, the invention provides composition and method of making the same and purposes that a kind of tool removes bromhidrosis function, said composition safety is high, have no side effect, skin irritation is low, can effectively kill the antibacterial causing bromhidrosis, thus can for the preparation of the medicine for the treatment of bromhidrosis, be used for the treatment of bromhidrosis, and administration time is short.The preparation method technological process of said composition is very simple, easy to operate.
Realizing the technical scheme that above-mentioned purpose of the present invention adopts is:
Tool, except a compositions for bromhidrosis function, comprises the component of following mass parts:
Tool, except a compositions for bromhidrosis function, comprises the component of following mass parts:
Tool, except a compositions for bromhidrosis function, comprises the component of following mass parts:
Described flavoring agent is Borneolum Syntheticum and Oleum lavandula angustifolia one wherein, or the mixture of two kinds.
This tool also comprises the Borax of 0.1-1.0 part except the compositions of bromhidrosis function.
Tool, except a preparation method for the compositions of bromhidrosis function, comprises the steps:
1) tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water and flavoring agent is taken according to said ratio;
2) each component is mixed, stir.
The compositions that tool removes bromhidrosis function is being prepared except the application in bromhidrosis medicine, and described medicine is spray.
Compared with prior art, its beneficial effect and advantage are in the present invention:
1) said composition safety high, have no side effect, skin irritation is low, effectively can kill go out staphylococcus aureus and the corynebacterium that cause bromhidrosis, fundamentally solves the root causing bromhidrosis.Therefore, said composition can for the preparation of the medicine for the treatment of bromhidrosis, and this drug medication time is short, and cure rate is high, not easily recurs.Test shows, said composition is made spray and is used for the treatment of bromhidrosis, and bromhidrosis patient medication is after 1 month, and patient's bromhidrosis symptom of 85% is clearly better.
2) the preparation method technological process of said composition is extremely simple, and it is extremely convenient to operate, and environmentally safe, production cost is low, very economic environmental protection.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail.
Embodiment 1
Tool is except a compositions for bromhidrosis function, and its component is:
Above-mentioned tool, except the preparation method of the compositions of bromhidrosis function, the steps include:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water and Borneolum Syntheticum is taken according to said ratio;
2) each component is mixed, stir, obtain the compositions of this tool except bromhidrosis function.
The toxicity test of the compositions of test one, tool bromhidrosis function of the present invention
Reagent agent: the compositions of the present embodiment tool bromhidrosis function.
Test method:
Choose the mice 100 of body weight about 20 grams, male and female half and half.100 mices are divided into test group and matched group, each 50 of the mice of test group and matched group, and male and female half-and-half.The mice of test group and matched group is tested respectively as follows:
Test group: every mice administration (percutaneous dosing is painted on skin) dosage is 10mL/ days, continues three months;
Matched group: every mice feedwater (percutaneous dosing is painted on skin) dosage is 10mL/ days, continues three months;
After 3 months, the dead quantity of record mice, and calculate mortality rate.
Result of the test:
Experimental result is as following table:
Mortality rate (%) Test group Matched group
Female 3 4
Male 2 2
As seen from the above table, the mortality rate of test group mice and the mortality rate of control group mice similar.As can be seen here, tool of the present invention has no side effect except the compositions of bromhidrosis function.
Embodiment 2
Tool is except a compositions for bromhidrosis function, and its component is:
Above-mentioned tool, except the preparation method of the compositions of bromhidrosis function, the steps include:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water and Oleum lavandula angustifolia is taken according to said ratio;
2) each component is mixed, stir, obtain the compositions of this tool except bromhidrosis function.
Embodiment 3
Tool is except a compositions for bromhidrosis function, and its component is:
Above-mentioned tool, except the preparation method of the compositions of bromhidrosis function, the steps include:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water, Borneolum Syntheticum and Borax is taken according to said ratio;
2) each component is mixed, stir, obtain the compositions of this tool except bromhidrosis function.
Embodiment 4
Tool is except a compositions for bromhidrosis function, and its component is:
Above-mentioned tool, except the preparation method of the compositions of bromhidrosis function, the steps include:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water, Borneolum Syntheticum, Oleum lavandula angustifolia and Borax is taken according to said ratio;
2) each component is mixed, stir, obtain the compositions of this tool except bromhidrosis function.
Embodiment 5
Tool is except a compositions for bromhidrosis function, and its component is:
Above-mentioned tool, except the preparation method of the compositions of bromhidrosis function, the steps include:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water, Oleum lavandula angustifolia and Borax is taken according to said ratio;
2) each component is mixed, stir, obtain the compositions of this tool except bromhidrosis function
Embodiment 6
Below for the tool of embodiment 1 except the compositions of bromhidrosis function does the test for the treatment of bromhidrosis, thus the purposes of tool except the compositions of bromhidrosis function to be elaborated.
Conveniently use this tool except the compositions treatment bromhidrosis of bromhidrosis function, by this tool except the compositions of bromhidrosis function makes spray, its concrete grammar is: by the compositions sterilizing of this tool except bromhidrosis function, be sub-packed in vial or plastic bottle again, every bottle of 50-100 milliliter, encapsulates and installs Miniature spray jet.Certainly, the adjuvant that this tool can also add other except the compositions of bromhidrosis function is prepared into ointment and gel.
Testing program
Choosing has patient 400 example of obvious bromhidrosis symptom as experimenter, experimenter is divided into test group and matched group randomly, test group and each 200 people of matched group.The staphylococcus aureus at experimenter's axillary fossa place of first detection experiment group and matched group and coryneform quantity, and calculating mean value, then the experimenter of test group and matched group is tested respectively as follows:
Test group: the spray spraying axillary fossa place that the compositions using the tool of embodiment 1 to remove bromhidrosis function is made, early, middle and late spraying three times every day, continues 1 month.
Matched group: with water spraying axillary fossa place, early, middle and late spraying three times every day, continues 1 month.
After 1 month, the staphylococcus aureus at experimenter's axillary fossa place of detection experiment group and matched group and coryneform quantity again, and calculating mean value.
Result of the test
Before and after test, staphylococcus aureus and the coryneform quantity at experimenter's axillary fossa place are as shown in the table:
As seen from the above table, the spray spraying axillary fossa place that the tool of experimenter's use embodiment 1 of test group is made except the compositions of bromhidrosis function is after 1 month, and staphylococcus aureus and the coryneform quantity at axillary fossa place obviously reduce.As can be seen here, tool of the present invention has good anti-Staphylococcus aureus and coryneform effect except the compositions of bromhidrosis function, can, for the preparation of the medicine for the treatment of bromhidrosis, be used for the treatment of bromhidrosis, and therapeutic effect be good and administration time is short.
The compositions of test two, tool bromhidrosis function of the present invention is to human body skin irritation test
Reagent agent: the spray that the compositions of the tool bromhidrosis function of embodiment 1 is made
Test method:
Choosing has patient 50 people of obvious bromhidrosis symptom, and as test group, choosing does not have normal person 50 people of bromhidrosis symptom, as a control group.The equal administration of experimenter (percutaneous dosing is painted on skin) of test group and matched group 1 month.After 1 month, whether the skin of the experimenter of viewing test group and matched group, there is skin irritation symptom.
Experimental result:
Experimental result sees the following form:
Allergic symptom Matched group Test group
Erythema, edema, to fester Nothing Nothing
Vesicle, ulcer, hyperemia Nothing Nothing
As seen from the above table, the spray that the compositions of the tool bromhidrosis function of the skin of the experimenter of test group and matched group spraying embodiment 1 is made is after 1 month, all without allergic symptom.As can be seen here, the compositions of tool bromhidrosis function of the present invention is to human body skin nonirritant.

Claims (8)

1. tool is except a compositions for bromhidrosis function, it is characterized in that the component comprising following mass parts:
2. tool according to claim 1 is except the compositions of bromhidrosis function, it is characterized in that:
3. tool according to claim 1 is except the compositions of bromhidrosis function, it is characterized in that:
4. tool according to claim 1 is except the compositions of bromhidrosis function, it is characterized in that: described flavoring agent is Borneolum Syntheticum and Oleum lavandula angustifolia one wherein, or the mixture of two kinds.
5. tool according to claim 1 is except the compositions of bromhidrosis function, it is characterized in that: the Borax also comprising 0.1-1.0 part.
6. tool according to claim 1 is except a preparation method for the compositions of bromhidrosis function, it is characterized in that comprising the steps:
1) component tannic acid, hamameli tannin, aluminum chloride, ethanol, salicylic acid, distilled water and flavoring agent is taken according to proportioning according to claim 1;
2) each component is mixed, stir.
7. a tool according to claim 1 except the compositions of bromhidrosis function in preparation except the application in bromhidrosis medicine.
8. tool according to claim 7 is except the compositions of bromhidrosis function is preparing except the application in bromhidrosis medicine, it is characterized in that: described medicine is spray.
CN201510543025.0A 2015-08-28 2015-08-28 Composition having body odor removal function and preparation method and application thereof Pending CN105147770A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510543025.0A CN105147770A (en) 2015-08-28 2015-08-28 Composition having body odor removal function and preparation method and application thereof

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Application Number Priority Date Filing Date Title
CN201510543025.0A CN105147770A (en) 2015-08-28 2015-08-28 Composition having body odor removal function and preparation method and application thereof

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Publication Number Publication Date
CN105147770A true CN105147770A (en) 2015-12-16

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105832762A (en) * 2016-05-24 2016-08-10 广州南雪药业有限公司 Preparation for treating bromhidrosis and preparation method thereof
CN107875144A (en) * 2017-12-16 2018-04-06 王磊 A kind of combination of oral medication for treating depression
CN109481349A (en) * 2018-11-30 2019-03-19 宋月成 One kind, which is dispelled, savours facial treatment milk and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1977860A (en) * 2005-12-02 2007-06-13 天津市世雄科技发展有限公司 Sterized special agent for treating bromhidrosis
CN101151044A (en) * 2005-03-29 2008-03-26 汉高两合股份公司 Composition comprising beta-defensin 2
CN103933117A (en) * 2014-04-03 2014-07-23 邓发强 Product for deodorizing human body and objects

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101151044A (en) * 2005-03-29 2008-03-26 汉高两合股份公司 Composition comprising beta-defensin 2
CN1977860A (en) * 2005-12-02 2007-06-13 天津市世雄科技发展有限公司 Sterized special agent for treating bromhidrosis
CN103933117A (en) * 2014-04-03 2014-07-23 邓发强 Product for deodorizing human body and objects

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105832762A (en) * 2016-05-24 2016-08-10 广州南雪药业有限公司 Preparation for treating bromhidrosis and preparation method thereof
CN105832762B (en) * 2016-05-24 2019-02-01 广州南雪药业有限公司 A kind of preparation and preparation method thereof for treating body odour
CN107875144A (en) * 2017-12-16 2018-04-06 王磊 A kind of combination of oral medication for treating depression
CN109481349A (en) * 2018-11-30 2019-03-19 宋月成 One kind, which is dispelled, savours facial treatment milk and preparation method thereof

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Application publication date: 20151216