CN107569593A - One kind treats psoriasic ointment and preparation method thereof - Google Patents
One kind treats psoriasic ointment and preparation method thereof Download PDFInfo
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- CN107569593A CN107569593A CN201710763971.5A CN201710763971A CN107569593A CN 107569593 A CN107569593 A CN 107569593A CN 201710763971 A CN201710763971 A CN 201710763971A CN 107569593 A CN107569593 A CN 107569593A
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- ointment
- capsaicine
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Abstract
The invention discloses one kind to treat psoriasic ointment, is made up of following raw material according to parts by weight:100 120 parts of grape-kernel oil, 20 40 parts of aloe, 10 30 parts of hippophae rhamnoides fruit oil, 10 30 parts of fine jade precipice Malus spectabilis oil, celestial graceful 10 50 parts of 10 20 parts of G57,80 100 parts of glycerine, 0.4 0.6 parts of EDTA, 28 parts of sodium alginate, 46 parts of salicylic acid, 8 12 parts of VB6,2 10 parts of capsaicine, 10 20 parts of phellodendron extract, 10 50 parts of Baical Skullcap root P.E, 10 20 parts of Cortex Dictamni extract, 10 30 parts of purslane extract and shrubby sophora extract.The present invention also disclosed the preparation method of the ointment.Capsaicine and Chinese herbal medicine extract be combined with each other by the present invention, play a part of mutually promoting, quick to psoriasis treatment positive effect, and are free from side effects.
Description
Technical field
The present invention relates to field of medicaments, specifically one kind treats psoriasic ointment.
Background technology
Psoriasis, it is a kind of chronic inflammatory skin, the course of disease is longer, aggravates in the winter time more, shows and is with erythema, the scales of skin that peel off
It is main.Increased trend year by year is presented in the psoriasic incidence of disease in recent years, therefore finds antipsoriatics thing with significant
Clinical meaning.
Have some on the market at present and treat the external used medicines such as psoriasic ointment, patch, but in quick-acting and effective side
Face is ineffective and price costly.
Capsaicine is the main matter for causing acid in capsicum, is the capsicum bases separated from pepper fruit
Compound.Through substantial amounts of research have shown that capsaicine have it is very strong ease pain, antibacterial and antiinflammation, mainly used in field of medicaments at present
In the production of the preparation such as folk prescription or compound ointment agent, treatment of arthritis, myalgia, sprain for exercise and herpes zoster are widely used in
After leave the diseases such as neuralgia, and to human body is nontoxic, the side effect such as harmless, but people not yet apply and are treating psoriasic neck
Domain.
The content of the invention
It is an object of the invention to provide one kind to treat psoriasic ointment, is asked with solve to propose in above-mentioned background technology
Topic.
To achieve the above object, the present invention provides following technical scheme:
One kind treats psoriasic ointment, is made up of following raw material according to parts by weight:Grape-kernel oil 100-120 parts, aloe
Oily 20-40 parts, hippophae rhamnoides fruit oil 10-30 parts, fine jade precipice Malus spectabilis oil 10-30 parts, celestial graceful G57 10-20 parts, glycerine 80-100 parts, EDTA
0.4-0.6 parts, sodium alginate 2-8 parts, salicylic acid 4-6 parts, VB6 8-12 parts, capsaicine 2-10 parts, phellodendron extract 10-20
Part, Baical Skullcap root P.E 10-50 parts, Cortex Dictamni extract 10-20 parts, purslane extract 10-30 parts and shrubby sophora extract 10-50
Part.
As the further scheme of the present invention:Phellodendron extract, Baical Skullcap root P.E, Cortex Dictamni extract, purslane extraction
Thing and shrubby sophora extract are obtained using the ethanol soak extraction of mass fraction more than 90%, concentration and after reclaiming ethanol.
As the further scheme of the present invention:Capsaicine uses the water-soluble capsicum oleoresin of 10% peppery degree.
The preparation method of the psoriasic ointment for the treatment of, is comprised the following steps that:
Step 1, by grape-kernel oil, aloe, hippophae rhamnoides fruit oil, fine jade precipice Malus spectabilis oil and celestial graceful G57 stirring and dissolvings, obtain oil
Phase;
Step 2, by glycerine, EDTA, sodium alginate, salicylic acid, VB6, capsaicine, phellodendron extract, Baical Skullcap root P.E,
Cortex Dictamni extract, purslane extract and shrubby sophora extract mixing, then add to 1000 parts with deionized water and be well mixed,
Obtain aqueous phase;
Step 3, aqueous phase is slowly added into oil phase, continues stirring until ointment sizing, obtain semi-finished product;
Step 4, essential oil is keyed in semi-finished product and is well mixed, you can obtains finished product.
As the further scheme of the present invention:Essential oil is used in Rosemary Oil, eucalyptus citriodora essential oil and deodar essential oil extremely
Few one kind.
Compared with prior art, the beneficial effects of the invention are as follows:The raw material sources of the present invention are extensive, and formula is reasonable, prepare
Technique is simple, easy to operate, and production cost is low, suitable for large-scale industrial production;The present invention is by capsaicine and Chinese herbal medicine
Extract be combined with each other, and plays a part of mutually promoting, quick to psoriasis treatment positive effect, and makees without secondary
With.
Embodiment
The technical scheme of this patent is described in more detail with reference to embodiment.
Embodiment 1
One kind treats psoriasic ointment, takes grape-kernel oil 100g, aloe 20g, hippophae rhamnoides fruit oil 20g, fine jade precipice Malus spectabilis oil
20g and celestial graceful G57 20g stirring and dissolvings are to obtain oil phase.Take glycerine 80g, EDTA 0.5g, sodium alginate 5g, salicylic acid 5g,
VB6 10g, Capsaicin 3g, phellodendron extract, Baical Skullcap root P.E, Cortex Dictamni extract, purslane extract and shrubby sophora extract are total
Amount 115g, deionized water add to total amount 1000g, to obtain aqueous phase.Above-mentioned aqueous phase solution is slowly added in oil phase, persistently stirred
Mix, shaped to ointment, emulsification is complete, uniform and smooth, and appropriate Rosemary Oil, eucalyptus citriodora essential oil and deodar essence are added after undetermined type
Oil is well mixed, you can obtains scaly tetter ointment.
Through clinical test case 30, continuous medication is after 30 days, statistical result showed, wherein 16 are cured, effective 8,
Effective 3, invalid or exacerbation 3.Wherein total effective rate is 90%.Using this product without any side effect such as poisonous, harmful.
Embodiment 2
One kind treats psoriasic ointment, takes grape-kernel oil 100g, aloe 20g, hippophae rhamnoides fruit oil 20g, fine jade precipice Malus spectabilis oil
20g and celestial graceful G57 20g stirring and dissolvings are to obtain oil phase.Take glycerine 80g, EDTA 0.5g, sodium alginate 5g, salicylic acid 5g,
VB6 10g, Capsaicin 5g, phellodendron extract, Baical Skullcap root P.E, Cortex Dictamni extract, purslane extract and shrubby sophora extract are total
Amount 115g, deionized water add to 1000g, to obtain aqueous phase.Above-mentioned aqueous phase solution is slowly added in oil phase, lasting stirring, extremely
Ointment is shaped, and emulsification is complete, uniform and smooth, and adding appropriate Rosemary Oil, eucalyptus citriodora essential oil and deodar essential oil after undetermined type mixes
Close uniform, you can it is soft to obtain psoriasis.
Through clinical test case 30, continuous medication is after 30 days, statistical result showed, wherein 14 are cured, effective 8,
Effective 6, invalid or exacerbation 2.Wherein total effective rate is 93%.Using this product without any side effect such as poisonous, harmful.
Embodiment 3
One kind treats psoriasic ointment, takes grape-kernel oil 100g, aloe 20g, hippophae rhamnoides fruit oil 20g, fine jade precipice Malus spectabilis oil
20g and celestial graceful G57 20g stirring and dissolvings are to obtain oil phase.Take glycerine 80g, EDTA 0.5g, sodium alginate 5g, salicylic acid 5g,
VB6 10g, Capsaicin 7g, phellodendron extract, Baical Skullcap root P.E, Cortex Dictamni extract, purslane extract and shrubby sophora extract are total
Amount 115g, deionized water add to 1000g, to obtain aqueous phase.Above-mentioned aqueous phase solution is slowly added in oil phase, lasting stirring, extremely
Ointment is shaped, and emulsification is complete, uniform and smooth, and adding appropriate Rosemary Oil, eucalyptus citriodora essential oil and deodar essential oil after undetermined type mixes
Close uniform, you can obtain scaly tetter ointment.
Through clinical test case 30, continuous medication is after 30 days, statistical result showed, wherein 12 are cured, effective 9,
Effective 5, invalid or exacerbation 4.Wherein total effective rate is 86%.Using this product without any side effect such as poisonous, harmful
The effect of present invention is using the antibacterial of capsaicine, anti-inflammatory, capsaicine is added to the psoriasic ointment for the treatment of first
In, capsaicine is played the effect of its is antibacterial, anti-inflammatory under suitable capsaicin concentration, be unlikely to stimulate again and arrive skin.
The present invention with the addition of substantial amounts of Chinese herbal medicine extract, and substantial amounts of antibacterial, anti-inflammatory, Exfoliating Scrub etc. are contained in these Chinese herbal medicine extracts
Efficacy active component material, these active ingredient substances can play good phase with capsaicine during treatment is psoriasic
The effect mutually promoted.The inventive method technique is simple, easy to operate, is adapted to industrialized production, and cost is relatively low, and therapeutic effect is bright
It is aobvious, it is quick.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity
Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
It is appreciated that other embodiment.
Claims (5)
1. one kind treats psoriasic ointment, it is characterised in that is made up of following raw material according to parts by weight:Grape-kernel oil 100-
120 parts, aloe 20-40 parts, hippophae rhamnoides fruit oil 10-30 parts, fine jade precipice Malus spectabilis oil 10-30 parts, celestial graceful G57 10-20 parts, glycerine 80-
100 parts, EDTA 0.4-0.6 parts, sodium alginate 2-8 parts, salicylic acid 4-6 parts, VB6 8-12 parts, capsaicine 2-10 parts, golden cypress carry
Thing 10-20 parts, Baical Skullcap root P.E 10-50 parts, Cortex Dictamni extract 10-20 parts, purslane extract 10-30 parts and kuh-seng is taken to carry
Take thing 10-50 parts.
2. the psoriasic ointment for the treatment of according to claim 1, it is characterised in that the phellodendron extract, radix scutellariae extraction
Thing, Cortex Dictamni extract, purslane extract and shrubby sophora extract using mass fraction more than 90% ethanol soak extraction,
Obtained after concentration and recovery ethanol.
3. the psoriasic ointment for the treatment of according to claim 1, it is characterised in that the capsaicine is using 10% peppery degree
Water-soluble capsicum oleoresin.
A kind of 4. preparation method of psoriasic ointment for the treatment of as described in claim 1-3 is any, it is characterised in that specific step
It is rapid as follows:
Step 1, by grape-kernel oil, aloe, hippophae rhamnoides fruit oil, fine jade precipice Malus spectabilis oil and celestial graceful G57 stirring and dissolvings, obtain oil phase;
Step 2, by glycerine, EDTA, sodium alginate, salicylic acid, VB6, capsaicine, phellodendron extract, Baical Skullcap root P.E, shaggy-fruited dittany
Bark extract, purslane extract and shrubby sophora extract mixing, then add to 1000 parts with deionized water and be well mixed, obtain
Aqueous phase;
Step 3, aqueous phase is slowly added into oil phase, continues stirring until ointment sizing, obtain semi-finished product;
Step 4, essential oil is keyed in semi-finished product and is well mixed, you can obtains finished product.
5. the preparation method of the psoriasic ointment for the treatment of according to claim 4, it is characterised in that the essential oil is using fan
Repeatedly at least one of essential oil, eucalyptus citriodora essential oil and deodar essential oil.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115400064A (en) * | 2022-09-26 | 2022-11-29 | 沈军 | Essential oil skin care formula |
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CN1385187A (en) * | 2002-05-09 | 2002-12-18 | 淄博市职业病防治院 | Medicinal composition, its preparation process and use in treating psoriasis |
CN101406564A (en) * | 2007-10-08 | 2009-04-15 | 江苏中康药物科技有限公司 | External-use Chinese medicinal composition formulation and uses thereof |
WO2012145609A1 (en) * | 2011-04-21 | 2012-10-26 | Sunny Biodiscovery, Inc. | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
CN104815257A (en) * | 2015-05-12 | 2015-08-05 | 孙海辉 | External traditional Chinese medicine liquor for treating psoriasis |
CN105687459A (en) * | 2016-04-05 | 2016-06-22 | 颜泳峰 | Preparation method of traditional Chinese medicine composition for treating psoriasis |
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2017
- 2017-08-30 CN CN201710763971.5A patent/CN107569593A/en active Pending
Patent Citations (5)
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CN1385187A (en) * | 2002-05-09 | 2002-12-18 | 淄博市职业病防治院 | Medicinal composition, its preparation process and use in treating psoriasis |
CN101406564A (en) * | 2007-10-08 | 2009-04-15 | 江苏中康药物科技有限公司 | External-use Chinese medicinal composition formulation and uses thereof |
WO2012145609A1 (en) * | 2011-04-21 | 2012-10-26 | Sunny Biodiscovery, Inc. | Transoral methods and compositions for wrinkle reduction and cosmetic lip and facial augmentation |
CN104815257A (en) * | 2015-05-12 | 2015-08-05 | 孙海辉 | External traditional Chinese medicine liquor for treating psoriasis |
CN105687459A (en) * | 2016-04-05 | 2016-06-22 | 颜泳峰 | Preparation method of traditional Chinese medicine composition for treating psoriasis |
Non-Patent Citations (3)
Title |
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刘世任等: "《药剂学知识新编》", 30 November 2016 * |
张文义: "《内病外治临床指南》", 31 July 2016, 中医古籍出版社 * |
景作亮等: "辣椒碱的研究进展及应用", 《天津化工》 * |
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CN115400064A (en) * | 2022-09-26 | 2022-11-29 | 沈军 | Essential oil skin care formula |
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