CN101375837B - Medicament composition for treating dermatopathy as well as preparation method and use thereof - Google Patents
Medicament composition for treating dermatopathy as well as preparation method and use thereof Download PDFInfo
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- CN101375837B CN101375837B CN200810156581A CN200810156581A CN101375837B CN 101375837 B CN101375837 B CN 101375837B CN 200810156581 A CN200810156581 A CN 200810156581A CN 200810156581 A CN200810156581 A CN 200810156581A CN 101375837 B CN101375837 B CN 101375837B
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Abstract
The invention discloses a medication composition for curing skin disease, which comprises a bi-component of daubing liquid and daubing paste. The composition particularly comprises the following components with the weight percentage as follows: daubing liquid A: 8.0 to 16.0 percent of methyl salicylate, 2.0 to 5.0 percent of camphor, 2.0 to 5.0 percent of menthol, and 70 percent of ethanol complemented to 100 percent; daubing paste B: 0.5 to 1.0 percent of aureomycin hydrochloride, 0.5 to 5.0 percent of whiteruss, and vaseline complemented to 100 percent. The invention further discloses a method for preparing the medication composition and the application field of the medication. The medication composition has the beneficial effects that various harmful bacteria and virus which cause skin diseases are killed, various skin diseases such as acne, lip boil, blain, sudoral eruptions, erysipelas, periodontitis, etc. can be effectively cured; the development of inflammation can be prevented when the medication is applied once and can be cured by three days, and the cost of the medication composition is low.
Description
Technical field
The present invention relates to the dermopathic pharmaceutical composition of a kind of treatment.
Background technology
Human epidermal; Because external cause such as pruritus, high low temperature variation, high light, radioactivity and chemical substance and impaired; Or owing to inner reasons such as blood constituent variation, endocrine disturbance; Cause positions such as hair follicle in the skin, big eccrine gland, sebaceous gland, receive the infection of Propiobacterium, staphylococcus aureus, Staphylococcus albus, streptococcus and multiple fungus and virus, and it is sick that various skin takes place.
These germ dermatosiss have multiple seat skin ulcer, the comedo (be acne vulgaris, claim acne, skin sore again) that causes as increasing severely owing to gonadal hormone, infantile acne, hot acne, rosacea etc.; Also have furuncle, carbuncle, aphtha, lip boil, pustule, miliaria (being miliaria), erysipelas etc.
Treat dermatosis in the market, especially to medicines such as seat skin ulcer (like comedo), lip boil, pustule, periodontitis, therapeutic effect is not too desirable.
Summary of the invention
Technical problem to be solved by this invention provides a kind of pharmaceutical composition that can effectively treat a skin ulcer, lip boil, pustule, miliaria, erysipelas, periodontitis etc.
The technical problem that the present invention also will solve provides the dermopathic preparation of drug combination method of above-mentioned treatment.
The technical problem that the present invention also will solve provides the application of the dermopathic pharmaceutical composition of above-mentioned treatment in treatment seat skin ulcer, lip boil, pustule, miliaria, erysipelas and periodontitis.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is following:
The dermopathic pharmaceutical composition of a kind of treatment, it comprises masking liquid and is coated with the cream bi-component, specifically comprises following components in weight percentage:
Masking liquid A: methyl salicylate 8.0～16.0%, Camphora 2.0～5.0%, Mentholum 2.0～5.0%, 75% ethanol complements to 100%;
Be coated with cream B: chlortetracycline hydrochloride 0.5～1.0%, liquid paraffin 0.5～5.0%, vaseline complements to 100%.
The dermopathic pharmaceutical composition of treatment of the present invention has used the world today to treat dermopathic latest notion, promptly " opens skin (but not injuring skin), bactericidal antiphlogistic ".Adopting the effect of masking liquid A mainly is " opening skin ", utilizes the broad spectrum activity Tetracyclines antibiotics chlortetracycline hydrochloride that is coated with among the cream B to carry out bactericidal antiphlogistic again.
Also can add among the masking liquid A and be no more than 1% pigment.
Prepare the method for the dermopathic pharmaceutical composition of above-mentioned treatment, comprise the steps:
(1) with the ethanol mixing of methyl salicylate and 75%, again Camphora and Mentholum are ground the back adding, stir, make masking liquid A until dissolving fully;
(2) with liquid paraffin, vaseline behind high temperature sterilize, it is for use to be cooled to room temperature; Chlortetracycline hydrochloride and liquid paraffin are mixed, grind to form fine and smooth pasty state; Divide 3～5 batches to add vaseline, grinding evenly promptly makes and is coated with cream B.
The application of the dermopathic pharmaceutical composition of above-mentioned treatment in treatment seat skin ulcer, lip boil, pustule, miliaria, erysipelas and periodontitis.
The method for using of the dermopathic pharmaceutical composition of treatment of the present invention is following: the affected part is cleaned with clear water, smeared a small amount of masking liquid A earlier, after half a minute, slightly firmly be coated with trowelling cream B approximately, every day sooner or later respectively once.When if the affected part ulceration comes to a head, then only need be coated with trowelling cream B, and need not exert oneself.But the affected part is when around eyes, and eyes can feel to have stimulation, and water cleans eyes and gets final product.
Beneficial effect: the dermopathic pharmaceutical composition of treatment of the present invention has adopted the world today to treat dermopathic latest notion: " opening skin, bactericidal antiphlogistic "; Can kill multiple pathogenic bacteria targetedly; And cost is lower, can effectively treat a skin ulcer, lip boil, pustule, miliaria, erysipelas and periodontitis etc., smears and once can suppress the affected part development; Sooner or later respectively be coated with once, can cure about three days.Curative effect is seen table 1.
The therapeutic effect of table 1 pharmaceutical composition of the present invention
| The dermatosis kind | Case load | Cure rate | Average cure time |
| Seat skin ulcer (comedo patient) | 80 | 100％ | 3 days |
| Lip boil | 80 | 100％ | 3.2 my god |
| Pustule | 40 | 98％ | 3.5 my god |
| Periodontitis | 80 | 100％ | 3 days |
| Miliaria | 60 | 100％ | 3 days |
| Erysipelas | 30 | 80％ | 3.5 my god |
The specific embodiment:
According to following embodiment, can understand the present invention better.Yet, those skilled in the art will readily understand that the described concrete material proportion of embodiment, process conditions and result thereof only are used to explain the present invention, and the present invention that should also can not limit in claims to be described in detail.
Embodiment 1:
The dermopathic pharmaceutical composition of a kind of treatment, it comprises following component:
Masking liquid A: methyl salicylate 10g, Camphora 2g, Mentholum 2g, 75% ethanol 85g; Chlorophyll 1g.
Be coated with cream B: chlortetracycline hydrochloride 0.5g, liquid paraffin 3g, vaseline 96.5g.
Prepare the method for the dermopathic pharmaceutical composition of above-mentioned treatment, comprise the steps:
(1) with the ethanol mixing of methyl salicylate and 75%, again Camphora and Mentholum are ground the back adding, stir, make masking liquid A until dissolving fully;
(2) with liquid paraffin, vaseline behind high temperature sterilize, it is for use to be cooled to room temperature; Chlortetracycline hydrochloride and liquid paraffin are mixed, grind to form fine and smooth pasty state; Divide 3 batches to add vaseline, grinding evenly promptly makes and is coated with cream B.
Embodiment 2:
The dermopathic pharmaceutical composition of a kind of treatment, it comprises following component:
Masking liquid A: methyl salicylate 12g, Camphora 2g, Mentholum 4g, 75% ethanol 82g.
Be coated with cream B: chlortetracycline hydrochloride 1g, liquid paraffin 5g, vaseline 94g.
Prepare the method for the dermopathic pharmaceutical composition of above-mentioned treatment, comprise the steps:
(1) with the ethanol mixing of methyl salicylate and 75%, again Camphora and Mentholum are ground the back adding, stir, make masking liquid A until dissolving fully;
(2) with liquid paraffin, vaseline behind high temperature sterilize, it is for use to be cooled to room temperature; Chlortetracycline hydrochloride and liquid paraffin are mixed, grind to form fine and smooth pasty state; Divide 4 batches to add vaseline, grinding evenly promptly makes and is coated with cream B.
Claims (4)
1. treat dermopathic pharmaceutical composition for one kind, it is characterized in that it comprises masking liquid and is coated with the cream bi-component, specifically comprises following components in weight percentage:
Masking liquid A: methyl salicylate 8.0～16.0%, Camphora 2.0～5.0%, Mentholum 2.0～5.0%, 75% ethanol complements to 100%;
Be coated with cream B: chlortetracycline hydrochloride 0.5～1.0%, liquid paraffin 0.5～5.0%, vaseline complements to 100%.
2. the dermopathic pharmaceutical composition of treatment according to claim 1 is characterized in that also can adding among the masking liquid A being no more than 1% pigment.
3. the method for preparing the dermopathic pharmaceutical composition of the described treatment of claim 1 is characterized in that this method comprises the steps:
(1) with the ethanol mixing of methyl salicylate and 75%, again Camphora and Mentholum are ground the back adding, stir, make masking liquid A until dissolving fully;
(2) with liquid paraffin, vaseline behind high temperature sterilize, it is for use to be cooled to room temperature; Chlortetracycline hydrochloride and liquid paraffin are mixed, grind to form fine and smooth pasty state; Divide 3～5 batches to add vaseline, grinding evenly promptly makes and is coated with cream B.
4. the application of the dermopathic pharmaceutical composition of the described treatment of claim 1 in preparation treatment seat skin ulcer, lip boil, pustule, miliaria, erysipelas and periodontitis medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810156581A CN101375837B (en) | 2008-10-09 | 2008-10-09 | Medicament composition for treating dermatopathy as well as preparation method and use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810156581A CN101375837B (en) | 2008-10-09 | 2008-10-09 | Medicament composition for treating dermatopathy as well as preparation method and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101375837A CN101375837A (en) | 2009-03-04 |
| CN101375837B true CN101375837B (en) | 2012-09-05 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200810156581A Expired - Fee Related CN101375837B (en) | 2008-10-09 | 2008-10-09 | Medicament composition for treating dermatopathy as well as preparation method and use thereof |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111840560B (en) * | 2020-07-24 | 2021-09-03 | 广州医科大学 | Application of calcium ionophore in leucoderma treatment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282583A (en) * | 1999-07-29 | 2001-02-07 | 伍淑兰 | Exterior-applied ointment |
| CN1647803A (en) * | 2004-01-20 | 2005-08-03 | 北京东方凯恩医药科技有限公司 | Chinese medicine composition plaster for external anti-inflammation and analgetics |
-
2008
- 2008-10-09 CN CN200810156581A patent/CN101375837B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1282583A (en) * | 1999-07-29 | 2001-02-07 | 伍淑兰 | Exterior-applied ointment |
| CN1647803A (en) * | 2004-01-20 | 2005-08-03 | 北京东方凯恩医药科技有限公司 | Chinese medicine composition plaster for external anti-inflammation and analgetics |
Non-Patent Citations (2)
| Title |
|---|
| 《药学服务指南丛书》编委会.樟脑薄荷柳酯乳膏.《非处方药使用手册》.2005,第22-23页. * |
| 谭健华.薄荷醇促进抗生素、抗菌药的透皮作用研究.《广东医学》.1995,第16卷(第8期),556-557. * |
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| CN101375837A (en) | 2009-03-04 |
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