CN105796942A - Formula for improving physical strength of animal or human body - Google Patents

Formula for improving physical strength of animal or human body Download PDF

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Publication number
CN105796942A
CN105796942A CN201610136148.7A CN201610136148A CN105796942A CN 105796942 A CN105796942 A CN 105796942A CN 201610136148 A CN201610136148 A CN 201610136148A CN 105796942 A CN105796942 A CN 105796942A
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China
Prior art keywords
extract
formula
animal
physical power
human physical
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Pending
Application number
CN201610136148.7A
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Chinese (zh)
Inventor
卢志斌
沈秋阳
刘家兴
卢绍基
潘大仁
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XIAMEN TASMAN BIO-TECH Co Ltd
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XIAMEN TASMAN BIO-TECH Co Ltd
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Priority to CN201610136148.7A priority Critical patent/CN105796942A/en
Publication of CN105796942A publication Critical patent/CN105796942A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a formula for improving the physical strength of an animal or human body. The formula is prepared from the following components in percentage by weight: 10-30% of dendrobium officinale extract, 5-15% of herba cistanche extract, 5-15% of rhizoma polygonati extract, 10-30% of maca extract, 5-15% of morinda officinalis extract, 5-15% of oat extract, 5-15% of oyster extract and 5-15% of rhizoma curculiginis seed extract. The formula is made into buccal tablets or capsules. The formula is applied to a mice experiment; and compared with a control group (normal saline), a pure dendrobium officinale extract powder group and a pure maca extract powder group, the exhaustive swimming time of mice is obviously prolonged, the content of hepatic glycogens is obviously increased, and the content of serum urea nitrogen is obviously reduced.

Description

A kind of formula improving animal or human physical power
Technical field
The present invention relates to Chinese medicine health-care field, particularly relate to a kind of formula improving animal or human physical power.
Background technology
People are under fast playing the life with high pressure at present, and physical condition declines day by day, and people always feel to be short of physical strength, The most tired.In the case of not getting enough athletic exercise, how the problem solving people of science, becomes more and more important.
Summary of the invention
It is an object of the invention to provide a kind of muscle power that improves, supplementary energy, the raising animal of tonifying YANG or the formula of human physical power.
For achieving the above object, the present invention provides a kind of formula improving animal or human physical power, it is characterised in that by following Each composition of percentage by weight prepares,
Herba Dendrobii extract 10-30%;
Herba Cistanches extract 5-15%;
Rhizoma Polygonati extract 5-15%;
Maca extract 10-30%;
Radix Morindae Officinalis extract 5-15%;
Oat extract 5-15%;
Sea oyster extract 5-15%;
Rhizoma Curculiginis seed extract 5-15%.
Further, each composition of following percentage by weight prepare,
Herba Dendrobii extract 10-26%;
Herba Cistanches extract 5-12%;
Rhizoma Polygonati extract 5-12%;
Maca extract 17-30%;
Radix Morindae Officinalis extract 5-11%;
Oat extract 7-15%;
Sea oyster extract 8-15%;
Rhizoma Curculiginis seed extract 7-15%.
Further, buccal tablet or capsule it are prepared as.
The present invention also protects the described formula of animal or human physical power that improves for improving the purposes of animal or human physical power.
The present invention also protects the described formula of animal or human physical power that improves for strengthening the purposes of animal or body immunity.
The present invention also protects the described formula of animal or human physical power that improves for improving human body or the use of animal body hepatic glycogen content On the way.
The present invention also protects the described formula of animal or human physical power that improves for reducing human body or animal body serum urea nitrogen content Purposes.
Herba Dendrobii of the present invention has the function of nourishing YIN and benefiting blood, and Qing Dynasty's " property of medicine opinion " says the long-pending essence of Herba Dendrobii energy the kidney invigorating, nourishing the stomach Cloudy, physical strength profiting.Herba Dendrobii is contained within the polysaccharose substance enriched.Experiment proves that dendrobium polysaccharide has and strengthens immunologic function Effect, can strengthen the peritoneal macrophage phagocytic activity to chicken red blood cell.Herba Dendrobii can improve stress ability, have well Resisting fatigue, the effect of anoxia enduring.When the Herba Dendrobii in inventive formulation is more than the consumption of 30 weight %, can cause frightened Faint.Less than the amount of 10 weight %, then can not play enhancing immunologic function and effect of resisting fatigue very well.
Herba Cistanches extract of the present invention, Herba Cistanches can increase glycogen deposit, reduces muscle after exercise breaks down proteins, promotees Make mitochondrion generation adaptability loose and hypertrophy, to meet the energy required for muscle contraction and rehabilitation.Yang deficiency can be significantly improved The synthesis level of RNA and DNA in animal liver spleen, has obvious physical strength reinforcing, antifatigue effect to yang deficiency syndrome.Herba Cistanches is many Sugar has significant impact to formation and the activity of human lymphocyte, and it can increase the breeder reaction of lymphocyte, thus increases The immunologic function of strong body.When the Herba Cistanches content in inventive formulation is more than 15 weight %, depletion fire syndrome going up can be caused.
Rhizoma Polygonati of the present invention can play the effect of resisting fatigue by the generation of suppression serum urea nitrogen, when in inventive formulation When Rhizoma Polygonati content is more than 15 weight %, can slight abdominal distention.
Maca of the present invention contains abundant ferrum, the composition such as protein, aminoacid, mineral zinc, taurine.These Nutrient, for opposing resisting fatigue, strengthens muscular endurance, alleviates sports fatigue, firm immune system, promotes human body and exempts from Epidemic disease power plays an important role.When the Maca content in inventive formulation is more than 30 weight %, easily causes and get angry.
Radix Morindae Officinalis of the present invention has puts on weight and antifatigue effect.
Rhizoma Curculiginis seed of the present invention all has certain potentiation to humoral immunization and cellular immunization, when the celestial being in inventive formulation When thatch seed content exceedes weight 15%, heart-rate-turbulence can be caused.
Each composition of the present invention all uses extract, and the effective ingredient of extract is higher.The preparation method of extract is, will Herba Dendrobii, Herba Cistanches, Rhizoma Polygonati, Maca, Radix Morindae Officinalis, Rhizoma Curculiginis seed, Herba bromi japonici, sea oyster are crushed to 60 mesh respectively;Again will be as Herba Dendrobii powder flooding, concentrates extracting solution suction concentration tank, i.e. uses the field of Chinese medicines to commonly use method for concentration at 90 DEG C Concentrating this extracting solution under the conditions of Zuo You, extracting solution after described concentration is spray-dried i.e. obtains Herba Dendrobii extract powder;Other Extract herewith step.
Formula of the present invention is used for mouse experiment, and compares (normal saline) group, Pure dendrobium officinale kimura et migo powder group and pure Maca Powder group is compared, and mice swimming time is obviously prolonged, hepatic glycogen content significantly improves, and serum urea nitrogen content substantially drops Low.Absolutely prove that the formula of the present invention has the effect improving muscle power.
Detailed description of the invention
Embodiments of the invention are described below in detail, and the example of described embodiment is intended to for explaining the present invention, and is not understood that For limitation of the present invention.Unreceipted concrete technology or condition person in embodiment, according to the skill described by the document in this area Art or condition or carry out according to product description.Agents useful for same or instrument unreceipted production firm person, be and can pass through city Available from conventional products.
Embodiment 1: improve the preparation of muscle power formula
Raw material is shown in Table 1;
The raw materials used table of each embodiment of table 1 (percentage by weight)
Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Herba Dendrobii extract 30 20 10 26
Herba Cistanches extract 15 10 5 12
Rhizoma Polygonati extract 10 12 5 15
Maca extract 20 17 30 10
Radix Morindae Officinalis extract 10 11 5 15
Oat extract 5 10 15 7
Sea oyster extract powder 5 10 15 8
Rhizoma Curculiginis seed extract 5 10 15 7
Preparation method:
Buccal tablet:
Pulverize: Herba Dendrobii, Herba Cistanches, Rhizoma Polygonati, Maca, Radix Morindae Officinalis, Rhizoma Curculiginis seed, Herba bromi japonici, sea oyster are crushed to respectively 60 mesh;
Extract: obtaining the extract of various material, step is as follows: such as Herba Dendrobii extract: Herba Dendrobii powder water logging Carry, extracting solution suction concentration tank is concentrated, i.e. use the field of Chinese medicines to commonly use method for concentration and under the conditions of about 90 DEG C, concentrate this carry Taking liquid, extracting solution after described concentration is spray-dried i.e. obtains Herba Dendrobii extract powder.
Mixing: take Herba Dendrobii extract powder, Herba Cistanches extract powder, Rhizoma Polygonati extract powder, Maca extract by weight Powder, Radix Morindae Officinalis extract powder, oat extract powder, sea oyster extract powder, Rhizoma Curculiginis seed extract powder add trough-type mixture machine and mix Close 30-50min.
Soft material processed: soft material made by the appropriate wetting agent ethanol of powder addition after mixing, and its humidity is agglomerating with hold, touches i.e. Dissipate and be as the criterion;
Pelletize: the soft material that will make is put comminutor and made wet granular;
It is dried: wet granular is put baking oven and is dried, it is desirable to baking temperature 70~80 DEG C, 3 hours time, make material moisture ≤ 1.5%;
Granulate: dried material carries out granulate, it is desirable to granule is uniform;
Tabletting: granule is placed in rotary tablet machine and carries out tabletting, 0.5g/ sheet.
Sterilizing, packaging.
Capsule:
Pulverize: Herba Dendrobii, Herba Cistanches, Rhizoma Polygonati, Maca, Radix Morindae Officinalis, Rhizoma Curculiginis seed are crushed to 60 mesh respectively;
Extract: obtaining the extract of various material, step is as follows: such as Herba Dendrobii extract: Herba Dendrobii powder water logging Carry, extracting solution suction concentration tank is concentrated, i.e. use the field of Chinese medicines to commonly use method for concentration and under the conditions of about 90 DEG C, concentrate this carry Taking liquid, extracting solution after described concentration is spray-dried i.e. obtains Herba Dendrobii extract powder.
Mixing: take Herba Dendrobii extract powder, Herba Cistanches extract powder, Rhizoma Polygonati extract powder, Maca extract by weight Powder, Radix Morindae Officinalis extract powder, oat extract egg albumen powder, sea oyster extract egg albumen powder, Rhizoma Curculiginis seed extract powder add slot type Mixer mixing 30-50min.
Fill 0.4g/ grain, sterilizing, packaging.
Embodiment 2: improve the preparation of muscle power formula
Raw material is shown in Table 1;
Preparation method is with embodiment 1.
Embodiment 3: improve the preparation of muscle power formula
Raw material is shown in Table 1;
Preparation method is with embodiment 1.
Embodiment 4: improve the preparation of muscle power formula
Raw material is shown in Table 1;
Preparation method is with embodiment 1.
Embodiment 5: compliance test result is tested
Blood urea nitrogen test kit, hepatic glycogen test kit (be purchased from Nanjing and build up biotechnology research institute)
Laboratory animal and packet thereof and feeding:
105 Kunming mouses (20 ± 2g), adaptability is eaten after feeding 3d, uses Excel random packet software, according to Body weight says that mice is randomly divided into 7 groups, often group 15, i.e. matched group (normal saline), Pure dendrobium officinale kimura et migo extract powder, Pure Lepidinm meyenii Walp powder, embodiment 1, embodiment 2, embodiment 3, embodiment 4. free choice feeding are drunk water, and feed 30d.
Table 2 test packet and disposition table
Test index and method: test mice feeds 30d, then carry out the mensuration of resisting fatigue indices.
Swim test |:
Gavage tested material 30d continuously, after last is to sample 30min, rat-tail root bears the sheet lead of Mouse Weight 5%, puts into water Temperature is 30 DEG C, in the swimming trunk of depth of water 35cm.With heating rod, water temperature is controlled at 30 DEG C, and by constant for room temperature at 25 DEG C. Every water tank once puts 5 mices, starts to swimming time (the heavy water-bed 10s of head) from swimming with stopwatch record, This time is the swimming time of mice.
The mensuration of serum urea nitrogen content:
Gavage tested material 30d continuously, after last is to sample 30min, it is 30 DEG C, the trip of depth of water 30cm that mice is put into water temperature In swimming case.Every water tank once puts 5 mices, not swimming with a load attached to the body 90min.Rest 60min after motion, will wipe around eyes Totally, pull out eyeball and take blood, separate serum, be measured with blood urea nitrogen test kit 0.5ml.
Hepatic glycogen measures:
Randomly selecting mice of the same size 10, continuous gavage tested material 30d, after last is to sample 30min, by mice Put into water temperature be 30 DEG C, in the swimming trunk of depth of water 30cm.Often group repeats to test twice, and every water tank once puts 5 mices, Not swimming with a load attached to the body 90min.All water temperature being adjusted to 30 DEG C before entering water, room temperature is constant at 25 DEG C every time.After swimming, place dies immediately Liver, blots with filter paper after frost normal saline rinsing, is measured with hepatic glycogen test kit.
Experimental result is shown in Table 3:
Table 3 tested material affects table to mice swimming time, hepatic glycogen content and serum urea nitrogen content
From the results, it was seen that embodiment 1-4 group is than Pure dendrobium officinale kimura et migo extract powder group and pure Maca extract powder group Mice swimming time is obviously prolonged, hepatic glycogen content significantly improves, and serum urea nitrogen content substantially reduces, with matched group Ratio, then effect becomes apparent from.Fully prove that the formula of the present invention has the effect improving muscle power.
Although above it has been shown and described that embodiments of the invention, it is to be understood that above-described embodiment is exemplary, Being not considered as limiting the invention, those of ordinary skill in the art is without departing from the principle of the present invention and the situation of objective Under above-described embodiment can be changed within the scope of the invention, revise, replace and modification.

Claims (7)

1. the formula improving animal or human physical power, it is characterised in that be prepared into by each composition of following percentage by weight Arrive,
Herba Dendrobii extract 10-30%;
Herba Cistanches extract 5-15%;
Rhizoma Polygonati extract 5-15%;
Maca extract 10-30%;
Radix Morindae Officinalis extract 5-15%;
Oat extract 5-15%;
Sea oyster extract 5-15%;
Rhizoma Curculiginis seed extract 5-15%.
Improve animal or the formula of human physical power the most according to claim 1, it is characterised in that by following percentage by weight Each composition prepare,
Herba Dendrobii extract 10-26%;
Herba Cistanches extract 5-12%;
Rhizoma Polygonati extract 5-12%;
Maca extract 17-30%;
Radix Morindae Officinalis extract 5-11%;
Oat extract 7-15%;
Sea oyster extract 8-15%;
Rhizoma Curculiginis seed extract 7-15%.
3. improve animal or the formula of human physical power described in any one of claim 1 or 2, it is characterised in that be prepared as buccal tablet Or capsule.
4. improve the formula of animal or human physical power described in any one of claim 1 or 2 for improving animal or human physical power Purposes.
5. the formula improving animal or human physical power described in any one of claim 1 or 2 is used for strengthening animal or body immunity Purposes.
6. the formula improving animal or human physical power described in any one of claim 1 or 2 is used for improving human body or animal body glycogen The purposes of former content.
7. the formula improving animal or human physical power described in any one of claim 1 or 2 is used for reducing human body or animal body serum The purposes of urea nitrogen content.
CN201610136148.7A 2016-03-10 2016-03-10 Formula for improving physical strength of animal or human body Pending CN105796942A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610136148.7A CN105796942A (en) 2016-03-10 2016-03-10 Formula for improving physical strength of animal or human body

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610136148.7A CN105796942A (en) 2016-03-10 2016-03-10 Formula for improving physical strength of animal or human body

Publications (1)

Publication Number Publication Date
CN105796942A true CN105796942A (en) 2016-07-27

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101537034B (en) * 2009-04-10 2011-03-23 云南南药医药发展有限公司 Functional health care product containing maca and preparation method thereof
CN103211959A (en) * 2013-05-13 2013-07-24 陕西立众制药有限公司 Traditional Chinese medicine composition used for tonifying yang and preparation method thereof
CN103966067A (en) * 2013-01-31 2014-08-06 鲁南制药集团股份有限公司 Traditional Chinese medicine health wine and production process thereof
CN104257748A (en) * 2014-09-05 2015-01-07 洛阳华以生物工程有限公司 Health product formula
CN104435749A (en) * 2014-11-11 2015-03-25 浙江省医学科学院 Dendrobium officinale compound preparation as well as preparation method and application of dendrobium officinale compound preparation
CN104432046A (en) * 2014-12-09 2015-03-25 重庆综艺营养科技有限责任公司 Male health product for daily use
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Publication number Priority date Publication date Assignee Title
CN101537034B (en) * 2009-04-10 2011-03-23 云南南药医药发展有限公司 Functional health care product containing maca and preparation method thereof
CN103966067A (en) * 2013-01-31 2014-08-06 鲁南制药集团股份有限公司 Traditional Chinese medicine health wine and production process thereof
CN103211959A (en) * 2013-05-13 2013-07-24 陕西立众制药有限公司 Traditional Chinese medicine composition used for tonifying yang and preparation method thereof
CN104257748A (en) * 2014-09-05 2015-01-07 洛阳华以生物工程有限公司 Health product formula
CN104435749A (en) * 2014-11-11 2015-03-25 浙江省医学科学院 Dendrobium officinale compound preparation as well as preparation method and application of dendrobium officinale compound preparation
CN104432046A (en) * 2014-12-09 2015-03-25 重庆综艺营养科技有限责任公司 Male health product for daily use
CN104522656A (en) * 2014-12-22 2015-04-22 威海百合生物技术股份有限公司 Health food for improving masculine physiological function

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