CN105770440A - Traditional Chinese medicine preparation for treating cerebral concussion - Google Patents

Traditional Chinese medicine preparation for treating cerebral concussion Download PDF

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Publication number
CN105770440A
CN105770440A CN201610203877.XA CN201610203877A CN105770440A CN 105770440 A CN105770440 A CN 105770440A CN 201610203877 A CN201610203877 A CN 201610203877A CN 105770440 A CN105770440 A CN 105770440A
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radix
chinese medicine
grams
caulis
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刘军
武传红
于华香
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating cerebral concussion, and belongs to the technical field of traditional Chinese medicines. Aiming at the causes of formation of concussion, an inventor selects the traditional Chinese medicines, of rauwolfia twig and leaves, shrubby breynia roots, papillose epipactis, piliferousstem aster herb, glabrous gardneria stem, Chinese ixora roots, hispid Chinese knotweed roots, salviae miltiorrhizae, velvety clovershrub roots, fivelobed grape, tuber fleeceflower stem, medical angiopteris rhizome, alpine swertia, irkutsk anemone rhizome and benzoin, with the effects of activating blood circulation, opening orifices, inducing resuscitation, ascending lucidity, descending turbidity and promoting blood circulation to remove blood stasis to prepare a decoction according to the theory of traditional Chinese medicine syndrome differentiation. Through a clinical experiment, the total effective rate reaches 96%.

Description

A kind of Chinese medicine preparation treating cerebral concussion
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation treating cerebral concussion.
Background technology
Cerebral concussion refers to that of short duration loss of consciousness and the loss of memory occurs in craniocerebral injury, without the organic lesion of clear and definite cerebral tissue structure.It is considered that cerebral concussion is only the transient dysfunction of brain physiological function;Electronic Speculum issues existing at pathological changes such as mitochondrial swelling, aixs cylinder swelling and white matter extracellular edema.Primary disease clinical manifestation is headache and dizzy, feel sick, tinnitus, insomnia forgetfulness, with vomiting, can there is restlessness or drowsiness simultaneously in child, and red tongue, tongue are white.At present, treatment cerebral concussion being lacked active drug, the shortcoming of Western medicine is that action target spot is single, toxic side effect, treats thorough not.Inventor, in clinical practice for many years, utilizes treatment by Chinese herbs cerebral concussion, not only achieves good curative effect, and side effect is little.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treating cerebral concussion.Cerebral concussion motherland medical science claims " brain shake wound ", " brain gas shock wound ", " brain shake wound " etc..Cerebral concussion is due to wound, makes channels stasis blocking, and QI-blood circulation is smooth, deficiency of marrow-reservoir and cause the symptoms such as headache, dizziness, can Complicated by Cerebral Edema cerebral hemorrhage etc. time serious.Chinese traditional treatment should be invigorated blood circulation sensible, opening and closing refreshment, ascending the clear and descending the turbid, blood circulation promoting and blood stasis dispelling.
It is an object of the invention to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment cerebral concussion is made up of the Chinese medicine of following weight portion: Caulis et folium Rauvolfiae Verticillatae 12-16 part, Radix Breyniae fruticosae 4-8 part, Herba Epipactidis papillosae 12-18 part, Herba Asteris lasiocladi 8-14 part, Caulis Gardeniae angustifoliae 12-18 part, Radix Ixorae Chinensis 30-40 part, Radix Polygoni hispidi 6-12 part, Radix Salviae Miltiorrhizae 4-8 part, Radix Campylotropis Cavaleriei 20-30 part, Cortex Vitis Quinquangularis Radicis 5-9 part, Caulis Polygoni Multiflori 7-11 part, Rhizoma Angiopteridis Officinalis 12-16 part, Herba Swertiae heteranthae 5-9 part, Rhizoma Anemones Altaicae 2-4 part, Benzoinum 1-3 part.
Preferred: Caulis et folium Rauvolfiae Verticillatae 14 parts, Radix Breyniae fruticosae 6 parts, Herba Epipactidis papillosae 15 parts, Herba Asteris lasiocladi 11 parts, Caulis Gardeniae angustifoliae 16 parts, Radix Ixorae Chinensis 35 parts, Radix Polygoni hispidi 9 parts, Radix Salviae Miltiorrhizae 6 parts, 25 parts of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 7 parts, Caulis Polygoni Multiflori 9 parts, Rhizoma Angiopteridis Officinalis 14 parts, Herba Swertiae heteranthae 7 parts, Rhizoma Anemones Altaicae 3 parts, Benzoinum 2 parts.
Preparation method: traditionally make decoction.
Fang Zhong: Caulis et folium Rauvolfiae Verticillatae dispel the wind blood pressure lowering, clots absorbing removing toxic substances;Radix Breyniae fruticosae expelling wind and clearing away heat, dissipating blood stasis for subsidence of swelling;Herba Epipactidis papillosae invigorating the spleen and replenishing QI, Shu Yu and in;Herba Asteris lasiocladi relieving the exterior syndrome by diaphoresis, regulating QI to relieve pain;Caulis Gardeniae angustifoliae settling five organs, logical nine orifices, except rheumatism, solve cold and heat;Radix Ixorae Chinensis promoting the circulation of QI to relieve pain, promoting blood circulation to remove obstruction in the collateral;Radix Polygoni hispidi restores menstrual flow and invigorates blood circulation, removing toxic substances of stopping blooding;Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, calm the nerves and allay excitement;Radix Campylotropis Cavaleriei dredge the meridian passage, relaxing muscles and tendons network, convergence pain relieving;Cortex Vitis Quinquangularis Radicis regulating menstruation and activating blood, qi-restoratives leukorrhagia stopping;Caulis Polygoni Multiflori tranquilizing by nourishing the heart, dredging collateral dispel the wind;Rhizoma Angiopteridis Officinalis tranquilizing mind, the meridian dredging;Herba Swertiae heteranthae suppressing liver-wind, heart tonifying nourish blood, regulating menstruation, control dizziness, neurasthenia;Rhizoma Anemones Altaicae is had one's ideas straightened out, and eliminating phlegm, a surname that dispels the wind is wet, stomach invigorating removing toxic substances;Benzoinum is had one's ideas straightened out and is warded off dirty, qi and blood circulation promotion.
Beneficial effects of the present invention: the Chinese medicine preparation of the present invention can effectively treat cerebral concussion, and all medicines are harmonious, altogether tool is invigorated blood circulation effect sensible, opening and closing refreshment, the feature such as treatment cerebral concussion has determined curative effect, has no side effect, cure rate height, instant effect, taking convenience.
Clinical data
1, case selection: selecting the cerebral concussion patients 100 example clinical observation made a definite diagnosis, patient is randomly divided into treatment group and matched group, treatment group 50 example, wherein male 30 example, women 30 example, 33~70 years old age, 50 years old mean age, the course of disease 1~3 year;Matched group 50 example, wherein male 32 example, women 28 example, 34~70 years old age, 51 years old mean age, the course of disease 1~3 year;Treatment group and the course of disease of two groups of cases of matched group, degrees of symptoms are basically identical, without significant difference, have comparability.
2, Therapeutic Method: treatment group takes the Chinese medicine preparation of the present invention, weigh Caulis et folium Rauvolfiae Verticillatae 14 grams, Radix Breyniae fruticosae 6 grams, Herba Epipactidis papillosae 15 grams, Herba Asteris lasiocladi 11 grams, Caulis Gardeniae angustifoliae 16 grams, Radix Ixorae Chinensis 35 grams, Radix Polygoni hispidi 9 grams, Radix Salviae Miltiorrhizae 6 grams, 25 grams of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 7 grams, Caulis Polygoni Multiflori 9 grams, Rhizoma Angiopteridis Officinalis 14 grams, Herba Swertiae heteranthae 7 grams, Rhizoma Anemones Altaicae 3 grams, Benzoinum 2 grams, traditionally make decoction oral, every day 1 dose, morning, evening is divided to take for 2 times, within 8 days, it is a course for the treatment of, takes 2~3 courses for the treatment of continuously;Matched group takes ibuprofen, usual amounts of being grown up: oral, a 0.2~0.4g, every 4~6 hours 1 time;Adult's maximum limitation of medication is generally 2.4g every day.
3, efficacy determination is cured: headache, dizziness, Nausea and vomiting, the symptom such as vexed are wholly absent, physical recovery health;Effective: headache, dizziness, Nausea and vomiting, the symptom such as vexed are clearly better, and health recovers gradually;Effective: subjective symptoms takes a turn for the better to some extent, headache, insomnia after even Animando or overwork;Invalid: by symptom after treating without alleviating or increasing the weight of.
4, therapeutic outcome: see following table.
Group n Cure Effective Effectively Invalid Total effective rate (%)
Treatment group 50 30 10 8 2 96
Matched group 50 20 8 5 17 66
Result above shows, the total effective rate for the treatment of group is apparently higher than matched group.Treatment group is generation without any side effects over the course for the treatment of.
Model case
Wang, man, 46 years old, builder, people from Qingdao.Patient was once kicked to the head by wooden stick, regained consciousness voluntarily after going into a coma 15 minutes, self-induction headache after waking up, dizzy, feel sick, be diagnosed as light concussion.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom substantially alleviates, and after continuing to take 1 course for the treatment of, physical recovery is normal.Follow up a case by regular visits to and do not recur so far.
Zou, female, 39 years old, civil servant, people from Linyi, Shandong.Patient cycles and falls into severe injury, with cerebral concussion and fracture, insobriety.The symptoms such as headache, dizziness, Nausea and vomiting, poor memory, constipation are still had after hospitalization.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom substantially alleviates, and after continuing to take 2 courses for the treatment of, health is fully recovered, sanity.
Detailed description of the invention
Embodiment one: weigh Caulis et folium Rauvolfiae Verticillatae 12 grams, Radix Breyniae fruticosae 4 grams, Herba Epipactidis papillosae 12 grams, Herba Asteris lasiocladi 8 grams, Caulis Gardeniae angustifoliae 12 grams, Radix Ixorae Chinensis 30 grams, Radix Polygoni hispidi 6 grams, Radix Salviae Miltiorrhizae 4 grams, 20 grams of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 5 grams, Caulis Polygoni Multiflori 7 grams, Rhizoma Angiopteridis Officinalis 12 grams, Herba Swertiae heteranthae 5 grams, Rhizoma Anemones Altaicae 2 grams, Benzoinum 1 gram, traditionally make decoction.
Embodiment two: Caulis et folium Rauvolfiae Verticillatae 14 grams, Radix Breyniae fruticosae 6 grams, Herba Epipactidis papillosae 15 grams, Herba Asteris lasiocladi 11 grams, Caulis Gardeniae angustifoliae 16 grams, Radix Ixorae Chinensis 35 grams, Radix Polygoni hispidi 9 grams, Radix Salviae Miltiorrhizae 6 grams, 25 grams of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 7 grams, Caulis Polygoni Multiflori 9 grams, Rhizoma Angiopteridis Officinalis 14 grams, Herba Swertiae heteranthae 7 grams, Rhizoma Anemones Altaicae 3 grams, Benzoinum 2 grams, traditionally makes decoction.
Embodiment three: weigh Caulis et folium Rauvolfiae Verticillatae 16 grams, Radix Breyniae fruticosae 8 grams, Herba Epipactidis papillosae 18 grams, Herba Asteris lasiocladi 14 grams, Caulis Gardeniae angustifoliae 18 grams, Radix Ixorae Chinensis 40 grams, Radix Polygoni hispidi 12 grams, Radix Salviae Miltiorrhizae 8 grams, 30 grams of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 9 grams, Caulis Polygoni Multiflori 11 grams, Rhizoma Angiopteridis Officinalis 16 grams, Herba Swertiae heteranthae 9 grams, Rhizoma Anemones Altaicae 4 grams, Benzoinum 3 grams, traditionally make decoction.

Claims (2)

1. the Chinese medicine preparation treating cerebral concussion, it is characterised in that the Chinese medicine preparation of this treatment cerebral concussion is made up of the Chinese medicine of following weight portion: Caulis et folium Rauvolfiae Verticillatae 12-16 part, Radix Breyniae fruticosae 4-8 part, Herba Epipactidis papillosae 12-18 part, Herba Asteris lasiocladi 8-14 part, Caulis Gardeniae angustifoliae 12-18 part, Radix Ixorae Chinensis 30-40 part, Radix Polygoni hispidi 6-12 part, Radix Salviae Miltiorrhizae 4-8 part, Radix Campylotropis Cavaleriei 20-30 part, Cortex Vitis Quinquangularis Radicis 5-9 part, Caulis Polygoni Multiflori 7-11 part, Rhizoma Angiopteridis Officinalis 12-16 part, Herba Swertiae heteranthae 5-9 part, Rhizoma Anemones Altaicae 2-4 part, Benzoinum 1-3 part.
2. a kind of Chinese medicine preparation treating cerebral concussion as claimed in claim 1, it is characterised in that the Chinese medicine preparation of this treatment cerebral concussion is made up of the Chinese medicine of following weight portion: Caulis et folium Rauvolfiae Verticillatae 14 parts, Radix Breyniae fruticosae 6 parts, Herba Epipactidis papillosae 15 parts, Herba Asteris lasiocladi 11 parts, Caulis Gardeniae angustifoliae 16 parts, Radix Ixorae Chinensis 35 parts, Radix Polygoni hispidi 9 parts, Radix Salviae Miltiorrhizae 6 parts, 25 parts of Radix Campylotropis Cavaleriei, Cortex Vitis Quinquangularis Radicis 7 parts, Caulis Polygoni Multiflori 9 parts, Rhizoma Angiopteridis Officinalis 14 parts, Herba Swertiae heteranthae 7 parts, Rhizoma Anemones Altaicae 3 parts, Benzoinum 2 parts.
CN201610203877.XA 2016-03-24 2016-03-24 Traditional Chinese medicine preparation for treating cerebral concussion Pending CN105770440A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038908A (en) * 2016-07-14 2016-10-26 张金华 Traditional Chinese medicinal preparation for treating cerebral concussion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125663A (en) * 2010-10-27 2011-07-20 宋爱民 Traditional Chinese medicinal preparation for treating cerebral concussion
CN104524058A (en) * 2014-12-19 2015-04-22 刘维生 Traditional Chinese medicine preparation for treating cerebral concussion and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102125663A (en) * 2010-10-27 2011-07-20 宋爱民 Traditional Chinese medicinal preparation for treating cerebral concussion
CN104524058A (en) * 2014-12-19 2015-04-22 刘维生 Traditional Chinese medicine preparation for treating cerebral concussion and preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038908A (en) * 2016-07-14 2016-10-26 张金华 Traditional Chinese medicinal preparation for treating cerebral concussion

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Application publication date: 20160720