CN115944701A - Compound traditional Chinese medicine for treating ischemic stroke and preparation method thereof - Google Patents

Compound traditional Chinese medicine for treating ischemic stroke and preparation method thereof Download PDF

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CN115944701A
CN115944701A CN202310159672.6A CN202310159672A CN115944701A CN 115944701 A CN115944701 A CN 115944701A CN 202310159672 A CN202310159672 A CN 202310159672A CN 115944701 A CN115944701 A CN 115944701A
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chinese medicine
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ischemic stroke
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刘博文
陈忠
汪仪
郑艳榕
周静
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Zhejiang Chinese Medicine University ZCMU
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Abstract

The invention discloses a compound traditional Chinese medicine for treating ischemic stroke and a preparation method thereof, wherein the compound traditional Chinese medicine comprises ligusticum wallichii, salvia miltiorrhiza, safflower, red paeony root, radix curcumae, astragalus mongholicus, angelica sinensis, caulis spatholobi, pinellia ternate and poria cocos, and the components are calculated according to the parts by mass: 10-20 parts of ligusticum wallichii, 8-12 parts of salvia miltiorrhiza, 4-6 parts of safflower, 7-9 parts of red paeony root, 6-12 parts of radix curcumae, 8-16 parts of astragalus mongholicus, 8-14 parts of angelica sinensis, 4-8 parts of caulis spatholobi, 5-11 parts of pinellia ternata and 5-11 parts of poria cocos; the invention has the beneficial effects that: the pinellia tuber, the curcuma aromatica and the tuckahoe have the effects of reducing phlegm, dredging collaterals and restoring consciousness by using; the use of the salvia miltiorrhiza, the red paeony root and the radix curcumae can cool blood and activate blood; the use of radix astragali, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, radix Angelicae sinensis, caulis Spatholobi, and radix Curcumae can benefit qi and promote blood circulation; the astragalus root, the angelica and the spatholobus stem can tonify qi and enrich blood; the whole formula has the effects of promoting blood circulation, eliminating phlegm, removing blood stasis and promoting tissue regeneration; is suitable for patients with ischemic stroke and syndrome of phlegm-blood stasis blocking collaterals in traditional Chinese medicine; the invention has definite curative effect and simple prescription; adopts Chinese herbal medicine preparation, is safe in proportioning and has no toxic or side effect.

Description

Compound traditional Chinese medicine for treating ischemic stroke and preparation method thereof
Technical Field
The invention belongs to the technical field of compound traditional Chinese medicines, and particularly relates to a compound traditional Chinese medicine for treating ischemic stroke and a preparation method thereof.
Background
Apoplexy is a common disease and frequently-occurring disease in clinic, the apoplexy incidence rate shows a trend of rising year by year along with the change of diet and living habits and the aging of population, language, motor function and other obstacles can be left if the treatment is not timely and accurately and effectively carried out, the living and living quality of a patient is seriously affected, and certain family economic burden is brought; combining with the modern imaging results of CT/MRI and the like, the stroke is divided into ischemic stroke and hemorrhagic stroke, and the ischemic stroke accounts for the majority of the stroke.
Ischemic stroke is the most important cause of death and disability of the old, and seriously affects the health and life quality of the old; the incidence rate of cerebrovascular diseases in China is about 120-180/10 ten thousand population, more than 150 ten thousand new cases are generated every year, wherein more than 60 percent of cases are patients with cerebral infarction; in addition, in recent years, the incidence of cerebrovascular diseases is in a trend of slowly rising, ischemic stroke belongs to the category of stroke in traditional Chinese medicine, and through thousands of years of clinical practice, traditional Chinese medicine accumulates a lot of experiences in treating the cerebrovascular diseases; the recovery period of apoplexy refers to 2 weeks to half a year after the onset of the disease, which is the key period of recovery, if the intervention can be effectively carried out in time, the degree of apoplexy sequelae can be effectively reduced, and the recovery period has important significance for improving the life quality.
The patent application number is CN200710132360.7, which discloses a traditional Chinese medicine for treating ischemic stroke, the traditional Chinese medicine comprises 15 g of rhizoma gastrodiae, 12 g of uncaria, 15 g of ligusticum wallichii, 20 g of salvia miltiorrhiza, 10 g of angelica sinensis, 12 g of leech and earthworm respectively, 6 g of raw rhubarb, 12 g of trichosanthes kirilowii maxim, 10 g of arisaema cum bile, 15 g of fresh bamboo juice, 10 g of rhizoma polygonati, 9 g of liquorice, and 12 g of leech and earthworm respectively; the dosage materials in the prescription are all natural Chinese herbal medicines, and then the traditional processing method is added to prepare the traditional Chinese medicine composition, the materials are easy to obtain, the prescription and the preparation method are simple, and the cost of preparing the medicine is low.
The patent application number is 201510195511.8, which discloses a traditional Chinese medicine for treating ischemic stroke, which comprises the following components: 10-30 parts of radix rehmanniae, 12-20 parts of radix scrophulariae, 6-15 parts of radix asparagi, 6-15 parts of glossy privet fruit, 6-18 parts of eclipta alba, 6-15 parts of radix salviae miltiorrhizae, 6-12 parts of cortex moutan, 6-15 parts of radix paeoniae rubra, 6-15 parts of rhizoma acori graminei and 15-30 parts of raw malt, and has the advantages of good treatment effect and low recurrence after treatment.
The traditional Chinese medicine has better curative effect on the stroke convalescence; however, the existing Chinese patent medicine has fixed components and dosage, is not flexible enough to be applied by people, has unsatisfactory curative effect, and uses earthworm, leech and other worm medicinal materials, so that the patient has psychological worry when taking the medicine, and the rehabilitation of the patient is influenced.
Disclosure of Invention
The invention aims to provide a compound traditional Chinese medicine for treating ischemic stroke and a preparation method thereof, and the compound traditional Chinese medicine is used based on syndrome differentiation, has definite curative effect, simple prescription, flexible proportion, safety and reliability.
In order to achieve the purpose, the invention provides the following technical scheme: a compound traditional Chinese medicine for treating ischemic stroke comprises ligusticum wallichii, salvia miltiorrhiza, safflower, red paeony root, radix curcumae, astragalus mongholicus, angelica sinensis, caulis spatholobi, pinellia ternate and poria cocos, and comprises the following components in parts by mass: 10-20 parts of ligusticum wallichii, 8-12 parts of salvia miltiorrhiza, 4-6 parts of safflower, 7-9 parts of red paeony root, 6-12 parts of radix curcumae, 8-16 parts of astragalus mongholicus, 8-14 parts of angelica sinensis, 4-8 parts of caulis spatholobi, 5-11 parts of pinellia ternata and 5-11 parts of poria cocos.
As a preferred technical scheme of the invention, the raw materials are prepared from the following raw materials in parts by mass: 10 parts of ligusticum wallichii, 8 parts of salvia miltiorrhiza, 4 parts of safflower, 7 parts of red paeony root, 6 parts of radix curcumae, 8 parts of astragalus mongholicus, 8 parts of angelica sinensis, 4 parts of caulis spatholobi, 5 parts of pinellia ternate and 5 parts of poria cocos.
As a preferred technical scheme of the invention, the raw materials are prepared from the following raw materials in parts by mass: 15 parts of ligusticum wallichii, 10 parts of salvia miltiorrhiza, 5 parts of safflower, 8 parts of red paeony root, 9 parts of radix curcumae, 12 parts of astragalus mongholicus, 11 parts of angelica sinensis, 6 parts of caulis spatholobi, 8 parts of pinellia ternate and 8 parts of poria cocos.
As a preferred technical scheme of the invention, the raw materials are prepared from the following raw materials in parts by mass: 20 parts of ligusticum wallichii, 12 parts of salvia miltiorrhiza, 6 parts of safflower, 9 parts of red paeony root, 12 parts of radix curcumae, 16 parts of astragalus mongholicus, 14 parts of angelica sinensis, 8 parts of caulis spatholobi, 11 parts of pinellia ternate and 11 parts of poria cocos.
The invention also discloses a preparation method of the compound traditional Chinese medicine for treating ischemic stroke, which comprises the following steps:
the method comprises the following steps: preparing raw materials: the raw materials comprise 10-20 parts of hemlock parsley, 8-12 parts of salvia miltiorrhiza, 4-6 parts of safflower, 7-9 parts of red paeony root, 6-12 parts of turmeric root-tuber, 8-16 parts of astragalus, 8-14 parts of angelica, 4-8 parts of suberect spatholobus stem, 5-11 parts of pinellia tuber and 5-11 parts of tuckahoe;
step two: drying: drying the raw materials;
step three: superfine grinding: carrying out superfine grinding on the dried raw materials;
step four: uniformly mixing: mixing the superfine pulverized materials.
As a preferable technical scheme of the present invention, in the second step, the moisture content after drying is less than 6%.
In the third step, the mixture is subjected to superfine grinding and then is sieved by a 100-200-mesh sieve.
As a preferred technical scheme of the invention, the raw materials are uniformly mixed and then can be filled into a medicine bag or a capsule to obtain oral powder or a capsule.
Compared with the prior art, the invention has the beneficial effects that:
the pinellia ternate, the radix curcumae and the poria cocos have the effects of reducing phlegm, dredging collaterals and restoring consciousness; the use of the salvia miltiorrhiza, the red paeony root and the radix curcumae can cool blood and activate blood; the use of radix astragali, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, radix Angelicae sinensis, caulis Spatholobi, and radix Curcumae can benefit qi, promote blood circulation, and dispel pathogenic wind; the astragalus root, the angelica and the spatholobus stem can tonify qi and enrich blood; the whole formula has the effects of promoting blood circulation, eliminating phlegm, removing blood stasis and promoting tissue regeneration; is suitable for patients with ischemic stroke, and is distinguished as wind phlegm stagnation type by traditional Chinese medicine; the invention has definite curative effect and simple prescription; adopts Chinese herbal medicine preparation, is safe in proportioning and has no toxic or side effect.
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FIG. 1 is a flow chart of the preparation method of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Referring to fig. 1, a first embodiment of the present invention provides a compound traditional Chinese medicine for treating ischemic stroke, which comprises ligusticum wallichii, salvia miltiorrhiza, safflower, red peony root, curcuma aromatica, astragalus, angelica sinensis, caulis spatholobi, pinellia ternate and poria cocos, and the components by mass portion are as follows: 10 parts of ligusticum wallichii, 8 parts of salvia miltiorrhiza, 4 parts of safflower, 7 parts of red paeony root, 6 parts of radix curcumae, 8 parts of astragalus mongholicus, 8 parts of angelica sinensis, 4 parts of caulis spatholobi, 5 parts of pinellia ternate and 5 parts of poria cocos.
Ligusticum wallichii: the rhizoma ligustici wallichii, pungent in flavor, capable of dissipating heat and dredging, has the effects of activating blood and removing stasis, and promoting qi circulation and relieving pain; can go up the vertex of the head and eyes, and has the functions of dispelling wind and relieving pain; animal experiments show that: rhizoma Ligustici Chuanxiong volatile oil can inhibit brain activity when applied in small amount, and has excitation effect on brain-extending respiratory center, motor center and spinal cord reflex center; the rhizoma ligustici wallichii has the function of enhancing blood circulation, and can accelerate the heart rate of animals, strengthen the myocardial contractility and dilate blood vessels; ligustrazine can inhibit pulmonary vasoconstriction caused by anoxia, and also has inhibitory effect on vasoconstriction caused by epinephrine or barium chloride;
red sage root: the red sage root is also named red ginseng, purple salvia root, red root and the like, is bitter in taste and slightly cold in nature, and enters heart and liver meridians, and has the effects of activating blood and removing stasis, stimulating the menstrual flow and relieving pain, clearing heart and relieving restlessness, cooling blood and eliminating carbuncle; the salvia miltiorrhiza bunge cathartic has the effects of bitter diarrhea, belongs to heart and liver meridians, mainly enters blood system, can promote blood circulation to remove blood stasis, remove blood stasis and promote tissue regeneration, and is a main medicine for treating frequent diseases of unsmooth blood circulation and blood stasis blockage; the red sage root enters heart and liver blood, has good passing effect, can activate blood and dissolve stasis, and is the essential drug for treating blood stasis; the salvia miltiorrhiza, which is cold in nature and enters heart meridian, has the functions of clearing heart fire, cooling blood, relieving restlessness and calming nerves, and can be used for treating hyperpyrexia, coma, dysphoria and insomnia caused by heat entering nutrient-blood and palpitation and insomnia caused by heart-blood deficiency; the salvia miltiorrhiza is cold in nature and enters the blood system, and is beneficial to clearing heat and cooling blood due to slight cold in nature, so the salvia miltiorrhiza can cool blood and activate blood, and can detoxify and eliminate rash; can dilate coronary artery, increase coronary blood flow, improve myocardial ischemia, infarction and heart function, regulate heart rhythm, dilate peripheral blood vessel, and improve microcirculation; the recovery period of red blood cells and hemoglobin is shortened, the reticulocytes are increased, and the tissue repair can be promoted; improving the activity of plasmin; prolonged bleeding and clotting time; inhibiting platelet aggregation and improving the rheological property of blood; contains cryptotanshinone and dihydrotanshinone, has inhibitory effect on in vitro staphylococcus, escherichia coli and Bacillus proteus, and Saviae Miltiorrhizae radix can inhibit blood lipid increase of high fat diet rabbit;
safflower: the part of the safflower used as the medicine is the dried flower of the safflower of the Compositae, the safflower is pungent in taste, warm in nature, and capable of entering the heart and liver meridians, has good effects of activating blood and dissolving stasis, is particularly suitable for people with blood stasis constitution and amenorrhea due to channel stagnation, and the safflower is pungent in property, capable of dispersing warm and dredging, and can be used for activating blood and dissolving stasis after entering the blood system; carthami flos has effects of relieving swelling and pain, and is suitable for various blood stasis diseases, such as thoracic obstruction, cardiodynia, costalgia, abdominal pain, subcutaneous cyanosis, and hemiplegia due to apoplexy; safflower also has the functions of promoting blood circulation and dredging collaterals so as to remove blood stasis and remove speckles; the safflower yellow contained in the safflower can expand peripheral blood vessels, inhibit platelet aggregation, enhance fibrinolysis and reduce the viscosity of whole blood, thereby playing a role in reducing blood pressure;
red peony root: radix Paeoniae Rubra is named as SHANYAO or CAOYAO, and has effects of nourishing yin, removing blood stasis, relieving pain, cooling blood, and relieving swelling;
turmeric root-tuber: the Yujin has the alias: yujin, yujing; nature and taste: pungent, bitter and cold in flavor, entering liver, heart and lung meridians; the pungent-flavor radix Curcumae can move energy and disperse, and can promote blood circulation and qi circulation; yu jin is pungent and bitter in flavor and can descend and purge, enter blood system of liver meridian and can cool blood, descend qi to stop bleeding, and is used for hematemesis, epistaxis and retrograde menstruation due to up-flow of qi and fire;
astragalus root: the astragalus root is sweet in taste and warm in nature; the astragalus membranaceus enters the lung channel and can tonify the qi of the body surface, is sweet and warm and enters the spleen channel, is a key medicine for tonifying spleen qi, enters the lung channel and can tonify the lung qi, can be used for treating symptoms such as cough weakness, shortness of breath, dyspnea, clear expectoration, low voice and the like caused by lung qi deficiency, can tonify the qi of the lung and the spleen, benefit the defense and strengthen the exterior to arrest sweating, can alleviate kidney lesion and has the function of diuresis, in addition, from the perspective of the traditional Chinese medicine, the spleen mainly transports and transforms water and dampness, and the spleen qi is deficient and fails to transport and transform, can tonify the spleen and tonify the body, can also promote diuresis to reduce edema, is one of important medicines for treating qi deficiency and edema, has the effect of nourishing blood, and is beneficial to enhancing the effect of hematopoiesis through the function of tonifying qi, so the astragalus membranaceus are also commonly used for treating the symptoms of blood deficiency and qi deficiency of both qi and blood deficiency; the astragalus has the cardiotonic effect, can increase the amplitude of cardiac contraction and increase the output, and has more obvious effect on poisoning or fatigue failure and heart; in addition, for the autoimmune reaction caused by the viral myocarditis, the astragalus can also inhibit the viral myocarditis by enhancing the immune function and has the function of promoting the induction of interferon; the astragalus has the effects of protecting the liver, enhancing the hematopoietic function and promoting the growth of white blood cells so as to enhance the immune function of a human body;
chinese angelica root: chinese angelica root, radix Angelicae sinensis is warm in nature, sweet and pungent in flavor; the angelica has strong blood replenishing effect, is called as a first blood replenishing medicine, is sweet and heavy in taste, can specially enrich blood, is suitable for various blood deficiency symptoms, has the functions of promoting blood circulation to remove blood stasis, warming and activating meridian, relieving pain and spasm, and relaxing bowel;
spatholobus stem: caulis Spatholobi is a Leguminosae plant with high medicinal value, mainly grows in forest, brush or valley forest, and has effects of promoting blood circulation, replenishing blood, regulating menstruation, relieving rigidity of muscles and activating collaterals; caulis Spatholobi has effects of dilating blood vessel, resisting blood platelet aggregation, promoting phosphorus metabolism, and can be used for treating angiosclerosis and lumbago and backache; treating aplastic anemia;
pinellia ternata: pinellia ternate is also called as pinellia ternate, is named as pinellia ternate, is used for three-step jumping, inscription and field conservation, has the effects of eliminating dampness and resolving phlegm, and is mainly used for treating phlegm-fluid dizziness and palpitation and wind-phlegm dizziness; now, pharmacological research also finds that the pinellia ternate can inhibit the activity of pepsin, protect gastric mucosa and promote the repair of the gastric mucosa;
tuckahoe, poria cocos: the tuckahoe is neutral in nature and sweet in taste, and enters heart, lung, spleen and kidney meridians, the tuckahoe is sweet and mild in taste, the sweet can tonify the body, the light can permeate the body, the medicine property is mild, the tuckahoe can eliminate pathogenic factors, strengthen body resistance and promote diuresis without damaging body resistance, is one of important medicinal materials in traditional Chinese medicines for promoting diuresis and reducing edema, and can be used for treating edema caused by various cold, heat, deficiency and excess and other reasons; poria has effects of invigorating heart and spleen, calming heart and tranquilizing mind, and can be used for treating deficiency of both heart and spleen, and deficiency of qi and blood; pachyman has effect of enhancing organism immunity, and can be administered to improve cell immunity of the elderly.
The pinellia ternate, the radix curcumae and the poria cocos have the effects of reducing phlegm, dredging collaterals and restoring consciousness;
the use of the salvia miltiorrhiza, the red paeony root and the radix curcumae can cool blood and activate blood;
the use of radix astragali, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, radix Angelicae sinensis, caulis Spatholobi, and radix Curcumae can benefit qi, promote blood circulation, and dispel pathogenic wind;
the astragalus root, the angelica and the spatholobus stem can tonify qi and enrich blood;
the whole formula has the effects of promoting blood circulation, eliminating phlegm, removing blood stasis and promoting tissue regeneration;
a preparation method of a compound traditional Chinese medicine for treating ischemic stroke comprises the following steps:
the method comprises the following steps: preparing raw materials: the raw materials comprise 10 parts of ligusticum wallichii, 8 parts of salvia miltiorrhiza, 4 parts of safflower, 7 parts of red paeony root, 6 parts of radix curcumae, 8 parts of astragalus mongholicus, 8 parts of angelica sinensis, 4 parts of caulis spatholobi, 5 parts of pinellia ternate and 5 parts of poria cocos;
step two: drying: drying the raw materials, wherein the water content of the dried raw materials is less than 6%;
step three: superfine grinding: micronizing the dried raw materials, and sieving with 100 mesh sieve;
step four: uniformly mixing: mixing the superfine pulverized materials, and packaging into medicinal bag or capsule to obtain oral powder.
Example 2
Referring to fig. 1, a second embodiment of the present invention is shown, which is based on the previous embodiment except that:
a compound traditional Chinese medicine for treating ischemic stroke comprises ligusticum wallichii, salvia miltiorrhiza, safflower, red paeony root, radix curcumae, astragalus mongholicus, angelica sinensis, caulis spatholobi, pinellia ternate and poria cocos, and the components are calculated according to parts by mass: 15 parts of ligusticum wallichii, 10 parts of salvia miltiorrhiza, 5 parts of safflower, 8 parts of red paeony root, 9 parts of radix curcumae, 12 parts of astragalus mongholicus, 11 parts of angelica sinensis, 6 parts of caulis spatholobi, 8 parts of pinellia ternate and 8 parts of poria cocos.
Preparing raw materials: the raw materials comprise 15 parts of ligusticum wallichii, 10 parts of salvia miltiorrhiza, 5 parts of safflower, 8 parts of red paeony root, 9 parts of radix curcumae, 12 parts of astragalus mongholicus, 11 parts of angelica sinensis, 6 parts of caulis spatholobi, 8 parts of pinellia ternate and 8 parts of poria cocos;
the dried raw materials are subjected to superfine grinding and then are sieved by a 150-mesh sieve.
To obtain capsule.
Example 3
Referring to fig. 1, a third embodiment of the present invention is shown, which is based on the previous embodiment except that:
a compound traditional Chinese medicine for treating ischemic stroke comprises ligusticum wallichii, salvia miltiorrhiza, safflower, red paeony root, radix curcumae, astragalus mongholicus, angelica sinensis, caulis spatholobi, pinellia ternate and poria cocos, and the components are calculated according to parts by mass: 20 parts of ligusticum wallichii, 12 parts of salvia miltiorrhiza, 6 parts of safflower, 9 parts of red paeony root, 12 parts of radix curcumae, 16 parts of astragalus mongholicus, 14 parts of angelica sinensis, 8 parts of caulis spatholobi, 11 parts of pinellia ternate and 11 parts of poria cocos.
Preparing raw materials: the raw materials comprise 20 parts of ligusticum wallichii, 12 parts of salvia miltiorrhiza, 6 parts of safflower, 9 parts of red paeony root, 12 parts of radix curcumae, 16 parts of astragalus mongholicus, 14 parts of angelica sinensis, 8 parts of caulis spatholobi, 11 parts of pinellia ternate and 11 parts of poria cocos;
the dried raw materials are subjected to superfine grinding and sieved by a 200-mesh sieve after superfine grinding.
To obtain oral powder.
The taking method comprises the following steps: the medicine is taken 3 g each time in the morning and evening for 20-40 days.
200 cases of patients with ischemic stroke are treated by using the compound traditional Chinese medicine, wherein 60 cases account for 30% of patients in one course of treatment; 70 cases are cured in two treatment courses, accounting for 35 percent; 40 cases are cured by more than three courses of treatment, accounting for 20 percent; the disease condition is controlled to be 30 cases, accounting for 15 percent; the traditional Chinese medicine composition has a remarkable curative effect on wind phlegm stasis type in the ischemic stroke recovery period.
Although embodiments of the present invention have been shown and described, with particular reference to the foregoing detailed description, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. A compound traditional Chinese medicine for treating ischemic stroke is characterized in that: comprises rhizoma ligustici wallichii, salvia miltiorrhiza, safflower, red paeony root, radix curcumae, astragalus, angelica, caulis spatholobi, pinellia ternate and poria cocos, and the components are calculated according to the parts by mass: 10-20 parts of ligusticum wallichii, 8-12 parts of salvia miltiorrhiza, 4-6 parts of safflower, 7-9 parts of red paeony root, 6-12 parts of radix curcumae, 8-16 parts of astragalus mongholicus, 8-14 parts of angelica sinensis, 4-8 parts of caulis spatholobi, 5-11 parts of pinellia ternata and 5-11 parts of poria cocos.
2. The compound traditional Chinese medicine for treating ischemic stroke according to claim 1, which is characterized in that: the raw materials are prepared from the following raw materials in parts by mass: 10 parts of ligusticum wallichii, 8 parts of salvia miltiorrhiza, 4 parts of safflower, 7 parts of red paeony root, 6 parts of radix curcumae, 8 parts of astragalus mongholicus, 8 parts of angelica sinensis, 4 parts of caulis spatholobi, 5 parts of pinellia ternate and 5 parts of poria cocos.
3. The compound traditional Chinese medicine for treating ischemic stroke according to claim 1, which is characterized in that: the raw materials are prepared from the following raw materials in parts by mass: 15 parts of ligusticum wallichii, 10 parts of salvia miltiorrhiza, 5 parts of safflower, 8 parts of red paeony root, 9 parts of radix curcumae, 12 parts of astragalus mongholicus, 11 parts of angelica sinensis, 6 parts of caulis spatholobi, 8 parts of pinellia ternate and 8 parts of poria cocos.
4. The compound traditional Chinese medicine for treating ischemic stroke according to claim 1, which is characterized in that: the raw materials are prepared from the following raw materials in parts by mass: 20 parts of ligusticum wallichii, 12 parts of salvia miltiorrhiza, 6 parts of safflower, 9 parts of red paeony root, 12 parts of radix curcumae, 16 parts of astragalus mongholicus, 14 parts of angelica sinensis, 8 parts of caulis spatholobi, 11 parts of pinellia ternate and 11 parts of poria cocos.
5. The preparation method of the compound traditional Chinese medicine for treating ischemic stroke according to any one of claims 1 to 4, characterized in that: the preparation method comprises the following steps:
the method comprises the following steps: preparing raw materials: the raw materials comprise 10-20 parts of ligusticum wallichii, 8-12 parts of salvia miltiorrhiza, 4-6 parts of safflower, 7-9 parts of red paeony root, 6-12 parts of radix curcumae, 8-16 parts of astragalus mongholicus, 8-14 parts of angelica sinensis, 4-8 parts of caulis spatholobi, 5-11 parts of pinellia ternate and 5-11 parts of poria cocos;
step two: and (3) drying: drying the raw materials;
step three: superfine grinding: carrying out superfine grinding on the dried raw materials;
step four: uniformly mixing: mixing the superfine pulverized materials.
6. The preparation method of the compound traditional Chinese medicine for treating ischemic stroke according to claim 5, characterized in that: in the second step, the water content after drying is less than 6%.
7. The preparation method of the compound traditional Chinese medicine for treating ischemic stroke according to claim 5, which is characterized in that: in the third step, the mixture is sieved by a sieve of 100 to 200 meshes after being crushed in an ultrafine way.
8. The preparation method of the compound traditional Chinese medicine for treating ischemic stroke according to claim 5, which is characterized in that: the raw materials are mixed evenly and then can be filled into medicine bags or capsules to obtain oral powder or capsules.
CN202310159672.6A 2023-02-20 2023-02-20 Compound traditional Chinese medicine for treating ischemic stroke and preparation method thereof Pending CN115944701A (en)

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* Cited by examiner, † Cited by third party
Title
郑敬肖等: "中西医结合治疗缺血性中风60例疗效观察", 河北中医, vol. 33, no. 04, pages 566 - 567 *

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Application publication date: 20230411