CN104524058A - Traditional Chinese medicine preparation for treating cerebral concussion and preparation method - Google Patents
Traditional Chinese medicine preparation for treating cerebral concussion and preparation method Download PDFInfo
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- CN104524058A CN104524058A CN201410803923.0A CN201410803923A CN104524058A CN 104524058 A CN104524058 A CN 104524058A CN 201410803923 A CN201410803923 A CN 201410803923A CN 104524058 A CN104524058 A CN 104524058A
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- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a traditional Chinese medicine preparation for treating cerebral concussion and a preparation method, belonging to the field of traditional Chinese medicines. The active ingredients of the traditional Chinese medicine preparation disclosed by the invention consist of the following raw materials: radix paeoniae alba, sarcopyramis nepalensis, apium graveolens, veined inula root, radix bupleuri, akebia stem, radix polygalae, rhizoma acori graminei, radix glycyrrhizae, poria cocos, radix acanthopanacis semticosi, flos albiziae, perilla leaf, herba eupatorii, long pepper and flos puerariae. The medicinal materials of the traditional Chinese medicine preparation disclosed by the invention are in proper compatibility and conform to the theories of traditional Chinese medicine and modern medicine; the traditional Chinese medicine preparation has the functions of activating blood and relieving stuffy orifices, opening block and refreshing mind, moving qi and harmonizing the middle and tranquilizing mind and activating collaterals, and has the advantages of convenience in use, good absorption effect and no adverse and toxic and side effects; and according to clinical verification, the traditional Chinese medicine preparation has the functions of invigorating the spleen and replenishing qi, soothing the liver and raising yang, moderating middle and relieving pain and nourishing blood and liver, can improve the internal and external environments of the body so as to treat or relieve the symptoms of cerebral concussion, and is suitable to be promoted and applied to clinical treatment and nursing of cerebral concussion.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of cerebral concussion.
Background technology
At once of short duration disordered brain function is there is in cerebral concussion after referring to that head is hit by external force.Pathological change is without significant change.Clinical manifestation is transience stupor, recent amnesia and the symptom such as headache, nausea and vomiting, and the no positive sign of neurologic check finds.It is the lightest a kind of brain injury, mostly can cure after treatment.It can occur separately, also can exist as intracranial hematoma merges with other craniocerebral injuries.
The clinical manifestation of cerebral concussion has: disturbance of consciousness, and degree is comparatively light and the time is of short duration, may be as little to several seconds or several minutes, but is no more than half an hour; Recent amnesia, can not recall injured situation at that time and injured process after clear-headed, but can clearly recall the thing before injured, often have headache, dizziness, feel sick, anorexia, vomiting, tinnitus, insomnia, photophobia, the symptom such as absent minded and bradykinesia.
The degree of cerebral concussion is heavier, and former dizzy fan's time is longer, and the phenomenon of its recent amnesia is also more remarkable, but harmless to the old memory in past.Cerebral concussion convalescent often has giddy, headache, feels sick, vomiting, tinnitus, how the symptoms such as insomnia, generally fade away to the several months in several weeks, but also have some patients to there is long-term giddy, headache, insomnia, irritated, the symptoms such as absent minded and hypomnesis, part is wherein had to be belong to convalescent period symptom, if overtime is still without when being clearly better 3 ~ June, except considering, whether except spiritedness factor, also should to check in detail, analyze, exist with or without delayed damage, be sure not to use " cerebral concussion sequela " in one word, increase the mental burden of patient on the contrary.
The method of current treatment cerebral concussion has needle point method, Drug therapy etc., and medicine generally adopts Naozhenning electuary, piracetam, aniracetam etc., but therapeutic effect is slow, and circulation is slow, and not clearly, long-term taking can injure liver, kidney, stomach etc.The traditional Chinese medical science is thought and is belonged to the category that traditional Chinese medical science wound faints, and its pathogenesis is qi-movement disturbance, clear YANG failing to ascend, and in clinical, common stasis of blood heresy closes key type and the large type of stasis of blood heresy resistance network type two, and tcm syndrome differentiation and treatment achieves very good effect.Therefore treat cerebral concussion medicine must safety, effectively, have no side effect, Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect is strong, instant effect, lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation to treat cerebral concussion, there is very important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of cerebral concussion, selected medical material compatibility is suitable, meets Chinese medicine and modern medicine is theoretical, have sensible, the opening and closing refreshment of invigorating blood circulation, circulation of qi promoting and in, active effect of calming the nerves, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, energy invigorating the spleen and replenishing QI, soothing the liver yang invigorating, slow middle pain relieving, nourishing blood to suppress the hyperactive liver, improve body internal and external environment, thus treatment or alleviate the various symptoms of cerebral concussion, be suitable for cerebral concussion clinical treatment and nursing is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for cerebral concussion, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of cerebral concussion, comprise following processing step:
(1) Radix Paeoniae Alba, Radix Inulae Nervosae, Radix Bupleuri, Radix Polygalae, Poria and Fructus Piperis Longi decontamination are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
(2) get Herba Sarcopyramis nepalensis, Flos Albiziae and Flos puerariae lobatae a little with vinegar liquid and water, mix thoroughly, slightly stewing, fry tack-free with slow fire and be degree, take out and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(3) by Herba Apii graveolentis, Folium Perillae and Herba Eupatorii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Caulis Akebiae, Rhizoma Acori Graminei, Radix Glycyrrhizae and Radix Et Caulis Acanthopanacis Senticosi Folium eucalypti globueli (Eucalyptus globulus Labill.) decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating and refluxing extraction 3 hours, reclaim ethanol, filter, under simmer down to 65 DEG C of environment, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(5) fine powder obtained by the thick paste obtained by above-mentioned steps (1), step (4) and step (2), step (3) is made tablet, be the Chinese medicine preparation of described treatment cerebral concussion.
The property of medicine of the present invention's Chinese medicine used is as follows:
The Radix Paeoniae Alba: sour in the mouth, hardship, cold nature; Return liver, spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.For the breast abdomen pain over the hypochondriac region, dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia." not Lu " carries: " clear and coherent blood vessels, in slow, dispelling malignant blood, expelling extravasated blood, anhydrate gas, sharp bladder, intestine and small intestine, subduing inflammation, row cold and heat time (controlling), and attacked by pestiferous factors is suffered from abdominal pain, lumbago.”
Herba Sarcopyramis nepalensis: sweet in the mouth, hardship, cold nature; Return lung, Liver Channel.Heat clearing away suppressing the hyperactive liver, eliminating damp, detoxifying.For cough due to lung-heat, the vertigo, Hiccough and deaf, day red photophobia, hepatitis, rheumatic arthralgia, traumatic injury wound is swollen, snake head-like infection, innominate toxic swelling.
Herba Apii graveolentis: sweet in the mouth, pungent, micro-hardship, cool in nature; Return liver, stomach, lung meridian.Calming liver and clearing heat, dispel the wind diuretic, hemostasis removing toxic substances.For dizziness due to hyperactivity of liver-YANG, headache due to pathogenic wind-heat, cough jaundice, urine leaching pain, hematuria metrorrhagia, leukorrhagia, skin infection toxic swelling." book on Chinese herbal medicine pushes away old " carries: " treating the liver sun is dizzy.Flushing conjunctival congestion, top-heavy, walking such as to be swayed the disease.”
Radix Inulae Nervosae: acrid in the mouth, hardship, warm in nature.Cold-dispelling, removing food stagnancy is stagnant, the meridian dredging.Control coldness and pain in the epigastrium, dyspeptic abdominal distention, dysphagic, stomachache, the empty hyperhidrosis of body, cold cough, rheumatism beriberi." Guizhou folk medicine " carries: " fill blood, hidroschesis.”
Radix Bupleuri: bitter in the mouth, cold nature; Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver yang invigorating.For alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse." Japan hanako materia medica " carries: " mend five kinds of strain and seven kinds of impairment, relieving restlessness spasmolytic, physical strength profiting, expectorant antitussive, profit cardiopulmonary, add essence and mend marrow, sky capable temperature disease is fanatical absolutely weary, breast side of body fullness caused by stagnant QI, forgetful.”
Caulis Akebiae: bitter in the mouth, cool in nature, GUIXIN, small intestinal, urinary bladder channel.Clearing away heat and promoting diuresis, blood circulation and channel invigorating.Red for red urine, stranguria with turbid discharge edema, irritable feverish sensation in the chest, larynx larynx pain, aphtha of the mouth and tongue, rheumatic arthralgia, galactostasis, amenorrhea dysmenorrhea." Japan hanako materia medica " carries: " relieving restlessness of feeling at ease, quenches the thirst and bring down a fever.Control forgetful, improve visual and auditory acuity, control nasal obstruction; Logical small intestinal, lower water, removing mass gathers clot, evacuation of pus, controls furuncle, and pain relieving expedites the emergence of lower eyelid, and woman's blood closes, and the moon waits irregular, disease when it is capable, headache and dizziness, thin bad breast knot, and stimulating milk secretion.”
Radix Polygalae: acrid in the mouth, hardship, warm in nature; GUIXIN, kidney, lung meridian.To calm the nerves Fructus Alpiniae Oxyphyllae, eliminating phlegm for diminishing swelling.For the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain." herbal classic " carries: ", except pathogen, sharp nine orifices, Fructus Alpiniae Oxyphyllae is intelligent, normal hearing and eyesight, does not forget, strong will times power for main cough with dyspnea damaging the spleen and stomach, tonifying for the deficiency.”
Rhizoma Acori Graminei: acrid in the mouth, hardship, warm in nature; GUIXIN, stomach warp.Have one's ideas straightened out eliminating phlegm, vital energy regualting and blood circulation-promoting, loose wind dries.For epilepsy syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury." not Lu " carries: " warming intestines and stomach, only normal urination, extremity arthralgia chiefly caused by damp pathogen, must not bend and stretch, children's's pyrexial malaria, and body accumulated heat is not understood, and can do to bathe soup for main deafness, carbuncle skin ulcer.Audition improvement order, beneficial intelligence.”
Radix Glycyrrhizae: sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong." Japan hanako materia medica " carries: " peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.”
Poria: sweet in the mouth, light, property is put down; GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia." Japan hanako materia medica ": " mend five kinds of strain and seven kinds of impairment, antiabortive, warm waist knee joint, happy Fructus Alpiniae Oxyphyllae, only forgetful.”
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, micro-hardship, warm in nature; Enter spleen, kidney, heart channel.Replenishing kidney, strengthening waist, benefiting vital QI for tranquillizing, promoting blood circulation to remove obstruction in the collateral.For kidney deficiency and bodily weakness, soreness of the waist and knees, children's's walking retardation in children, insufficiency of the spleen weak, deficiency of vital energy edema, inappetence, insomnia and dreamful sleep, forgetful, thoracic obstruction pain, anemofrigid-damp arthralgia, treating swelling and pain by traumatic injury." Chinese herbology " carries: " resolving stagnation for tranquilization, and network pain relieving.Treating the liver is strongly fragrant uncomfortable in chest, melancholy and discomfort, forgetful insomnia.Sometimes also for traumatic injury, carbuncle pain.”
Flos Albiziae: sweet in the mouth, micro-flat; Return lung meridian.Shu Yu, regulates the flow of vital energy, and calms the nerves, active.Uncomfortable in chest for pent-up, insomnia, forgetful, wind-fire ophthalmic, blurring of vision, pharyngalgia, carbuncle, traumatic injury pain." Chinese herbology " carries: " resolving stagnation for tranquilization, and network pain relieving.Treating the liver is strongly fragrant uncomfortable in chest, melancholy and discomfort, forgetful insomnia.Sometimes also for traumatic injury, carbuncle pain.”
Folium Perillae: acrid in the mouth, warm in nature; Return lung, spleen channel.Expelling cold and relieving exterior syndrome, dispersing lung-QI and dissipating phlegm, circulation of qi promoting and in, antiabortive, cowfish Eriocheir sinensis poison.For exterior syndrome due to wind-cold, cough with copious phlegm, crisp distension, nausea and vomiting, stomachache is vomited and diarrhoea, and nausea is got along well, and gestation is disliked cloudy, and ichthyophagy Eriocheir sinensis is poisoning." Bencao Tujing " carries: " logical heart channel, strengthening the spleen stomach.”
Herba Eupatorii: acrid in the mouth, property is put down; Return spleen, stomach, lung meridian.Clearing away summer-heat is warded off dirty, removing dampness regulating menstruation.For experiencing heat-damp in summer, cold and heat are had a headache, and accumulate in damp, gastral cavity painful abdominal mass is not hungry, sweet taste in the mouth greasy fur, menoxenia." modern Practical Chinese medicinal " carries: " be armaticity stomach invigorating, diaphoresis, diuretic.For emitting cold headache, nasal obstruction, nervous headache, infectiousness calentura, stomachache, waist nephralgia, calculus etc.”
Fructus Piperis Longi: acrid in the mouth, hot in nature; Return spleen, stomach warp.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.For trusted subordinate's cold type of pain, vomiting acid regurgitation, increased borborygmus and diarrhea, cold-dysentery, scrotal hernia, headache, nasal sinusitis, toothache.Amplification on Canon of Materia Medica carries: " walk cold air in the intestines and stomach, vomiting, fullness in the chest and abdomen pain.”
Flos puerariae lobatae: sweet in the mouth, cool in nature.Relieving acute alcoholism and recuperating the spleen, hemostasis.Thirsty for dysphoria with smothery sensation of getting sick from drinking too much wine, headache and dizzy, distension and fullness in the abdomen, vomiting acid regurgitation, anorexia, spits blood, discharging fresh blood stool." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control dizziness, the loathing of cold, high fever, relieving acute alcoholism and recuperating the spleen, wine dysentery, diet is not thought, and chest and diaphragm is glutted, and send out oh, vomit sour expectorant, alcoholism injures one's stomach, and spit blood, hematemesis, disappear heat.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, have sensible, the opening and closing refreshment of invigorating blood circulation, circulation of qi promoting and in, active effect of calming the nerves, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, energy invigorating the spleen and replenishing QI, soothing the liver yang invigorating, slow middle pain relieving, nourishing blood to suppress the hyperactive liver, improve body internal and external environment, thus treatment or alleviate the various symptoms of cerebral concussion, be suitable for cerebral concussion clinical treatment and nursing is applied.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicine preparation of cerebral concussion, comprise following processing step:
(1) Radix Paeoniae Alba, Radix Inulae Nervosae, Radix Bupleuri, Radix Polygalae, Poria and Fructus Piperis Longi decontamination are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
(2) get Herba Sarcopyramis nepalensis, Flos Albiziae and Flos puerariae lobatae a little with vinegar liquid and water, mix thoroughly, slightly stewing, fry tack-free with slow fire and be degree, take out and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(3) by Herba Apii graveolentis, Folium Perillae and Herba Eupatorii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Caulis Akebiae, Rhizoma Acori Graminei, Radix Glycyrrhizae and Radix Et Caulis Acanthopanacis Senticosi Folium eucalypti globueli (Eucalyptus globulus Labill.) decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating and refluxing extraction 3 hours, reclaim ethanol, filter, under simmer down to 65 DEG C of environment, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(5) fine powder obtained by the thick paste obtained by above-mentioned steps (1), step (4) and step (2), step (3) is made tablet, be the Chinese medicine preparation of described treatment cerebral concussion.
Usage and dosage: oral, every day 3 times, each 1 time of morning, noon and afternoon, each 1; Within 10 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of of the lighter, severe one can be fully recovered 3 ~ 4 courses for the treatment of.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
Select my institute or outer court to make a definite diagnosis the routine clinical observation of cerebral concussion patients 200, patient is divided into two groups at random, treatment group 100 example, wherein male 52 example, women 48 example, 12 years old ~ 60 years old age, 39 years old mean age, the course of disease 1 month ~ 2 years, average 1 year.Matched group 100 example, wherein male 50 example, women 50 example, 10 years old ~ 57 years old age, 30 years old mean age, the course of disease 1 month ~ 1 year, average 6 months.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 3 times, each 1 time of morning, noon and afternoon, each 1; Within 10 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of of the lighter, severe one can be fully recovered 3 ~ 4 courses for the treatment of.
Matched group takes brain compound recipe, oral.Each 0.8 ~ 1.6g (2 ~ 4), every day 3 times 4 ~ 8 weeks is a course for the treatment of.Child's consumption reduces by half.
3, efficacy determination:
(1) cure: headache stupor, nausea and vomiting, forget the transference cures such as forgetful, neurological disorder.
(2) effective: above-mentioned symptom is alleviated to some extent, physical recovery is healthy, and activity freely.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 74 examples, effective 18 examples, invalid 8 examples, cure rate 74%, total effective rate 92%.
Matched group cures 61 examples, effective 11 examples, invalid 28 examples, cure rate 61%, total effective rate 72%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, honest and clean certain, man, 17 years old, student, Zhongweiof Ningxia, northwest China people.Patient's head that conflicts with people bumps against on wall, is severe cerebral concussion through hospital diagnosis.Through treatment, after leaving hospital, brains is not still regained consciousness, constipation, the diseases such as ambiguous, slight Hypertension of speaking.Take Chinese medicine preparation of the present invention, after 1 course for the treatment of, health is rehabilitation gradually, and without the transference cure such as nausea and vomiting, stupor, physical recovery is healthy.Follow up a case by regular visits to and do not recur so far.
2, Xue, female, 26 years old, teacher, Ordos, inner Mongolia people.Patient takes thing upstairs, accidentally from upstairs falling down, goes into a coma then and there, household finds to be sent to hospital, is diagnosed as cerebral concussion and with fracture of lower leg, after hospitalize, symptom is clearly better, but the symptoms such as appearance is in the recent period dizzy, headache, stupor, and with forgeing forgetful phenomenon.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, the symptoms such as dizziness and headache obviously slow down, after continuing to take 1 course for the treatment of, in high spirits, and health is fully recovered, and does not recur again.
3, thunder, man, 30 years old, roadman, people from Yingkou, Liaoning.Patient falls down when lifting electric pole, and injure head and weigh two ribs wounded, blood stasis does not fall apart, severe coma, mind obstacle.After take 3 courses for the treatment of of Chinese medicine preparation of the present invention after, the state of an illness is fully recovered, and follows up a case by regular visits to and does not recur.
4, certain is congratulated, female, 37 years old, civil servant, Guangxi Yulin people.Patient collides with colleague's discord and falls into severe injury, with cerebral concussion and fracture, and insobriety.The symptom such as headache, dizzy, Nausea and vomiting, poor memory, constipation is still had after hospitalization.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and after continuing to take 2 courses for the treatment of, health is fully recovered, sanity.
5, Ni, female, 44 years old, peasant, people from Jilin songyuan.Patient throws from mountain because of carelessness, head injures internal injury outside many places, being sent to hospital, having stitched spininess, is cerebral concussion through hospital diagnosis, with vomiting, the disease such as dizzy, head swells and ache, constipation, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, after continuing to take 2 courses for the treatment of, physical recovery is normal, conscious.Follow up a case by regular visits to and do not recur so far.
6, soup, man, 52 years old, builder, people from Xingtai.Patient was once kicked to the head by wooden stick, went into a coma and regained consciousness voluntarily after 15 minutes, self-induction headache after waking up, dizzy, feel sick, be diagnosed as light concussion.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and after continuing to take 2 courses for the treatment of, physical recovery is normal.Follow up a case by regular visits to and do not recur so far.
Claims (5)
1. treat a Chinese medicine preparation for cerebral concussion, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Radix Paeoniae Alba 53 ~ 83 parts of Herba Sarcopyramis nepalensis 52 ~ 82 portions of Herba Apii graveolentis 50 ~ 80 parts of Radix Inulae Nervosaes 49 ~ 79 parts
Radix Bupleuri 47 ~ 77 portions of Caulis Akebiaes 45 ~ 75 parts of Radix Polygalaes 43 ~ 73 parts of Rhizoma Acori Graminei 41 ~ 71 parts
Radix Glycyrrhizae 39 ~ 69 parts of Poria 38 ~ 68 parts of Radix Et Caulis Acanthopanacis Senticosis 37 ~ 67 parts of Flos Albiziaes 36 ~ 66 parts
Folium Perillae 34 ~ 64 portions of Herba Eupatoriis 32 ~ 62 parts of Fructus Piperis Longi 30 ~ 60 parts of Flos puerariae lobataes 27 ~ 57 parts.
2. a kind of Chinese medicine preparation for the treatment of cerebral concussion according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Radix Paeoniae Alba 76 parts of Herba Sarcopyramis nepalensis 75 portions of Herba Apii graveolentis 73 parts of Radix Inulae Nervosaes 72 parts
Radix Bupleuri 70 portions of Caulis Akebiaes 68 parts of Radix Polygalaes 66 parts of Rhizoma Acori Graminei 64 parts
Radix Glycyrrhizae 62 parts of Poria 61 parts of Radix Et Caulis Acanthopanacis Senticosis 60 parts of Flos Albiziaes 59 parts
Folium Perillae 57 portions of Herba Eupatoriis 55 parts of Fructus Piperis Longi 53 parts of Flos puerariae lobataes 50 parts.
3. a kind of Chinese medicine preparation for the treatment of cerebral concussion according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Radix Paeoniae Alba 69 parts of Herba Sarcopyramis nepalensis 68 portions of Herba Apii graveolentis 66 parts of Radix Inulae Nervosaes 65 parts
Radix Bupleuri 63 portions of Caulis Akebiaes 61 parts of Radix Polygalaes 59 parts of Rhizoma Acori Graminei 57 parts
Radix Glycyrrhizae 55 parts of Poria 54 parts of Radix Et Caulis Acanthopanacis Senticosis 53 parts of Flos Albiziaes 52 parts
Folium Perillae 50 portions of Herba Eupatoriis 48 parts of Fructus Piperis Longi 46 parts of Flos puerariae lobataes 43 parts.
4. a kind of Chinese medicine preparation for the treatment of cerebral concussion according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
The Radix Paeoniae Alba 62 parts of Herba Sarcopyramis nepalensis 61 portions of Herba Apii graveolentis 59 parts of Radix Inulae Nervosaes 58 parts
Radix Bupleuri 56 portions of Caulis Akebiaes 54 parts of Radix Polygalaes 52 parts of Rhizoma Acori Graminei 50 parts
Radix Glycyrrhizae 48 parts of Poria 47 parts of Radix Et Caulis Acanthopanacis Senticosis 46 parts of Flos Albiziaes 45 parts
Folium Perillae 43 portions of Herba Eupatoriis 40 parts of Fructus Piperis Longi 38 parts of Flos puerariae lobataes 36 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of cerebral concussion, it is characterized in that: comprise following processing step:
The Radix Paeoniae Alba, Radix Inulae Nervosae, Radix Bupleuri, Radix Polygalae, Poria and Fructus Piperis Longi decontamination are cleaned, puts into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
Get Herba Sarcopyramis nepalensis, Flos Albiziae and Flos puerariae lobatae a little with vinegar liquid and water, mix thoroughly, slightly stewing, fry tack-free with slow fire and be degree, take out and dry, grind into powder, cross 120 order fine powders, for subsequent use;
(3) by Herba Apii graveolentis, Folium Perillae and Herba Eupatorii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(4) Caulis Akebiae, Rhizoma Acori Graminei, Radix Glycyrrhizae and Radix Et Caulis Acanthopanacis Senticosi Folium eucalypti globueli (Eucalyptus globulus Labill.) decontamination are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating and refluxing extraction 3 hours, reclaim ethanol, filter, under simmer down to 65 DEG C of environment, relative density is the thick paste of 1.11 ~ 1.18, for subsequent use;
(5) fine powder obtained by the thick paste obtained by above-mentioned steps (1), step (4) and step (2), step (3) is made tablet, be the Chinese medicine preparation of described treatment cerebral concussion.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105012741A (en) * | 2015-08-03 | 2015-11-04 | 孙希鹏 | Traditional Chinese medicine composition for treating cerebral concussion |
| CN105770440A (en) * | 2016-03-24 | 2016-07-20 | 刘军 | Traditional Chinese medicine preparation for treating cerebral concussion |
| CN105878481A (en) * | 2016-05-04 | 2016-08-24 | 刘军 | Traditional Chinese medicine composition for curing cerebral concussion sequelae |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579946A (en) * | 2012-02-05 | 2012-07-18 | 郭文斌 | Traditional Chinese medicine for treating postconcussion syndrome |
| CN103720961A (en) * | 2014-01-19 | 2014-04-16 | 王浦强 | Traditional Chinese medicine preparation for treating cerebral concussion and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102579946A (en) * | 2012-02-05 | 2012-07-18 | 郭文斌 | Traditional Chinese medicine for treating postconcussion syndrome |
| CN103720961A (en) * | 2014-01-19 | 2014-04-16 | 王浦强 | Traditional Chinese medicine preparation for treating cerebral concussion and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105012741A (en) * | 2015-08-03 | 2015-11-04 | 孙希鹏 | Traditional Chinese medicine composition for treating cerebral concussion |
| CN105770440A (en) * | 2016-03-24 | 2016-07-20 | 刘军 | Traditional Chinese medicine preparation for treating cerebral concussion |
| CN105878481A (en) * | 2016-05-04 | 2016-08-24 | 刘军 | Traditional Chinese medicine composition for curing cerebral concussion sequelae |
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