CN105770212A - 一种玛咖片 - Google Patents
一种玛咖片 Download PDFInfo
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- CN105770212A CN105770212A CN201610154875.6A CN201610154875A CN105770212A CN 105770212 A CN105770212 A CN 105770212A CN 201610154875 A CN201610154875 A CN 201610154875A CN 105770212 A CN105770212 A CN 105770212A
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Abstract
本发明属于保健品领域，公开了一种玛咖片，它所含的活性成分由下列重量份原料配比制备而成：玛咖2份、纤花耳草28份、回心草40份、乌泡刺35份、金刚散20份、软水黄连55份，还公开了其具有益气补血作用。
Description
技术领域
本发明涉及中药保健品技术领域，具体涉及一种玛咖片的制备方法及应用。
背景技术
红细胞偏低是患了小儿缺铁性贫血的临床表现。缺铁性贫血是指指机体对铁的需求与供给失衡，导致体内贮存铁耗尽红细胞的数量和血红蛋白的含量减少到一定程度时，继之红细胞内铁缺乏从而引起的贫血。缺铁性贫血是最常见的贫血。在生长发育最旺盛的婴儿时期，如果体内储存的铁被用尽而饮食中铁的含量不够，消化道对铁的吸收不足补充血容量和红细胞的增加，即可发生贫血。
发明内容
发明目的：为了解决上述问题，本发明的目的在于提供一种玛咖片的制备方法及应用。
技术方案：本发明的目的是通过如下的方案实现的：
一种玛咖片，它所含的活性成分由下列重量份原料配比制备而成：玛咖2份、纤花耳草28份、回心草40份、乌泡刺35份、金刚散20份、软水黄连55份。
所述玛咖片，制备方法步骤为：取上述除玛咖外其他药材合并，加水煎煮两次，合并煎液，浓缩至65℃时相对密度为1.10-1.20，加入乙醇，搅拌，使含醇量按体积百分比计算达65-85％，静置，过滤，滤液减压浓缩至65℃时相对密度为1.20-1.30并回收乙醇，将浓缩液喷雾干燥，所得颗粒粉碎成干浸膏粉，加入玛咖和辅料，制成片剂。
所述玛咖片，制备方法中煎煮条件为：第一次加水量为药材重量的8-12倍量，煎煮1-2h，第二次加水量为药材重量的6-10倍量，煎煮1-2h。
所述玛咖片，制备方法中喷雾干燥条件为：进风温度为90-110℃，出风温度为60-90℃，物料温度为60-90℃，雾化压力为0.2-0.5兆帕，喷雾速度为1-10ml/s。
所述玛咖片在制备补血保健品中的应用。
上述玛咖(学名：LepidiummeyeniiWalp)，(西班牙语：Maca)。主要出产于南美洲安第斯山脉和中国云南丽江，是一种十字花科植物。叶子椭圆，根茎形似小圆萝卜，可食用，是一种纯天然食品，营养成份丰富。玛咖的下胚轴可能呈金色或者淡黄色、红色、紫色、蓝色、黑色或者绿色。淡黄色的根最常见，形状、味道也最好。玛咖富含高单位营养素，对人体有滋补强身的功用。黑色玛咖是被公认为效果最好的玛卡，产量极少。玛咖原产高海拔山区，适宜在高海拔、低纬度、高昼夜温差、微酸性砂壤、阳光充足的土地中生长；种植地区主要分布于南美州安第斯山脉以及中国云南丽江的玉龙雪山地区，这两大主产区有较大面积的适种土地。而中国云南其他地区和新疆、西藏等地区也有少量种植。。
纤花耳草为茜草科耳草属植物纤花耳草HedyotistenellifloraBlume，以全草入药。夏秋采集,洗净晒干或鲜用。清热解毒，消肿止痛。用于癌症，阑尾炎，痢疾；外用治跌打损伤，蛇咬伤。
回心草，拉丁名为Rhodobryumroseum(Hedw.)Limpr.，辛、苦、平。养心安神，清肝明目。用于心悸怔忡，神经衰弱，外用治目赤肿痛。多年生苔藓植物；多成片散生；根态茎横走，有多数毛状假根。茎多枝，直立，紫红色。下部叶细小，膜质，鳞片状贴生于茎；茎顶叶绿色，较长大，多层丛集成莲座状，叶片倒卵状披针形或长倒卵形，上部有细锯齿，下部全缘，内卷，中肋长达叶尖。茎顶叶丛中簇生数个孢子体；蒴柄细长，上端弓曲，孢蒴下垂，红黄色，长卵圆柱形，蒴盖凸，有短喙。本发明以全草入药。
乌泡刺为蔷薇科悬钩子属植物灰白毛莓RubustephrodesHance，以根、叶及种子入药。夏季采叶，秋季采根及种子，晒干，本发明以叶入药。根：祛风除湿，活血调经。用于风湿疼痛，慢性肝炎，腹泻，痢疾，跌打损伤，月经不调。叶：止血，解毒。外用治外伤出血，痈疖疮疡。种子：补气益精。用于病后体虚，神经衰弱。
金刚散为葡萄科植物三裂叶蛇葡萄的根或根皮。祛风活络，消肿解毒，止血生肌。治风湿痹痛，跌打损伤，骨折，痈肿疔疮。本发明以根入药。
软水黄连为毛茛科唐松草属植物多枝唐松草ThalictrumramosumBoivin以全草入药。夏季采集，洗净晒干。苦，寒。清热利湿，解毒。用于目赤肿痛，痢疾，肝炎；外用治骨折，痈疖肿毒。野苦荬菜：清热解毒，散瘀止痛，止血，止带。用于子宫颈糜烂，白带过多，子宫出血，下腿淋巴管炎，跌打损伤，无名肿毒，乳痈疖肿，烧烫伤，阴道滴虫病。其余为药典品种。
有益效果：本发明全方相互配伍，清热解毒、益气补血，治疗气血虚效果明显。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：取纤花耳草28g、回心草40g、乌泡刺35g、金刚散20g、软水黄连55g药材混合，加水煎煮两次，第一次加水为药材重量的8倍量，煎煮1.5h，第二次加水为药材重量的6倍量，煎煮1h，合并煎液，滤过，滤液浓缩至相对密度1.10(65℃)，加适量乙醇使含醇量(体积分数)达65％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.10(65℃)的浸膏，经喷雾干燥(条件为进风温度为100℃，出风温度为80℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为5ml/s。)，粉碎成干浸膏粉，再加入玛咖粉末2g、糊精50g，用适量80％乙醇润湿，制软材，过14目筛制粒，70℃干燥，60目整粒，压片制备成片剂。
实施例2：取纤花耳草28g、回心草40g、乌泡刺35g、金刚散20g、软水黄连55g药材混合，加水煎煮两次，第次加水为药材重量的10倍量，煎煮2h，第二次加水为药材重量的8倍量，煎煮1h，合并煎液，滤过，滤液浓缩至相对密度1.15(65℃)，加适量乙醇使含醇量(体积分数)达75％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.25(65℃)的浸膏，经喷雾干燥(条件为进风温度为120℃，出风温度为90℃，物料温度为80℃，雾化压力为0.3兆帕，喷雾速度为7.5/s。)，粉碎成干浸膏50g，加入玛咖粉末2g、糊精50g，混合均匀，用适量80％乙醇润湿，制软材，过30目筛制粒，于70～80℃干燥，用60目筛整粒，压片，包衣，分装，外包装，送检合格，得成品。
实施例3：取纤花耳草28g、回心草40g、乌泡刺35g、金刚散20g、软水黄连55g药材混合，加水煎煮两次，第一次加水为药材重量的10倍量，煎煮1.5h，第二次加水为药材重量的8倍量，煎煮1.5h，合并煎液，滤过，滤液浓缩至相对密度1.15(65℃)，加适量乙醇使含醇量(体积分数)达75％，搅拌，静置24小时，滤过，滤液回收乙醇并浓缩至相对密度1.25(65℃)的浸膏，经喷雾干燥(条件为进风温度为120℃，出风温度为90℃，物料温度为90℃，雾化压力为0.4兆帕，喷雾速度为7.5/s。)，粉碎成干浸膏粉，过6号筛，加入玛咖粉末2g，淀粉50g，压片制备成片剂。
实施例4、本发明对失血小鼠的治疗作用
试验药品：按照上述实施例1的方法制备试验药品。
方法：对失血小鼠的影响ICR小鼠40只，♀♂各半，均分成4组(n＝10)。除生理盐水组外，其它组每只小鼠从眼眶静脉放血0.5ml，24h后再取血测全部各组指标，然后连续灌胃给药1周，末次给药1h后，从眼眶静脉丛取血用F-800全血小板分析仪测上述指标。
表1本发明对因失血所致红细胞减少的治疗作用
与模型组比较：*p<0.05**p<0.01
结果表明，放血小鼠经服用本发明治疗7天后，2个给药组分别于模型组比较，其红细胞显著高于模型组，接近生理盐水组。
Claims (5)
1.一种玛咖片，其特征在于，它所含的活性成分由下列重量份原料配比制备而成：玛咖2份、纤花耳草28份、回心草40份、乌泡刺35份、金刚散20份、软水黄连55份。
2.如权利要求1所述玛咖片，其特征在于，制备方法步骤为：取上述除玛咖外其他药材合并，加水煎煮两次，合并煎液，浓缩至65℃时相对密度为1.10-1.20，加入乙醇，搅拌，使含醇量按体积百分比计算达65-85％，静置，过滤，滤液减压浓缩至65℃时相对密度为1.20-1.30并回收乙醇，将浓缩液喷雾干燥，所得颗粒粉碎成干浸膏粉，加入玛咖和辅料，制成片剂。
3.如权利要求2所述玛咖片，其特征在于，制备方法中煎煮条件为：第一次加水量为药材重量的8-12倍量，煎煮1-2h，第二次加水量为药材重量的6-10倍量，煎煮1-2h。
4.如权利要求2所述玛咖片，其特征在于，制备方法中喷雾干燥条件为：进风温度为90-110℃，出风温度为60-90℃，物料温度为60-90℃，雾化压力为0.2-0.5兆帕，喷雾速度为1-10ml/s。
5.如权利要求1所述玛咖片在补血保健品中的应用。
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| CN103932189A (zh) * | 2014-04-29 | 2014-07-23 | 云南省农业科学院高山经济植物研究所 | 女性专用保健品 |
| CN104306617A (zh) * | 2014-11-02 | 2015-01-28 | 福州乾正药业有限公司 | 含有玛咖和阿萨伊果的组合物及其制备方法和应用 |
| CN105125873A (zh) * | 2015-10-03 | 2015-12-09 | 南京多宝生物科技有限公司 | 一种用于治疗高血脂症的药物制剂 |
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| CN103932189A (zh) * | 2014-04-29 | 2014-07-23 | 云南省农业科学院高山经济植物研究所 | 女性专用保健品 |
| CN104306617A (zh) * | 2014-11-02 | 2015-01-28 | 福州乾正药业有限公司 | 含有玛咖和阿萨伊果的组合物及其制备方法和应用 |
| CN105125873A (zh) * | 2015-10-03 | 2015-12-09 | 南京多宝生物科技有限公司 | 一种用于治疗高血脂症的药物制剂 |
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