CN105727242A - Traditional Chinese medicine preparation for treating internal heat toxin abundant type mastitis and preparing method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating internal heat toxin abundant type mastitis and preparing method of traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating internal heat toxin abundant type mastitis and a preparing method of the traditional Chinese medicine preparation, and belongs to the technical field of medicine.The traditional Chinese medicine preparation is prepared from, by weight, 10-20 parts of Yunnan spleenwort herb, 9-15 parts of radix scrophulariae, 15-20 parts of barbed skullcap herb, 5-13 parts of rhizomes of mioga ginger, 18-22 parts of wild buckwheat rhizome, 2-7 parts of caryota-like holly fern rhizomes, 6-12 parts of fritillary bulbs, 9-15 parts of fiveleaf akebia fruits, 6-15 parts of wood or roots of pedunculate acronychia and 3-10 parts of tremella fuciformis.The traditional Chinese medicine preparation has the effects of clearing away heat and toxic materials, invigorating blood circulation and eliminating carbuncles, discharging the liver and regulating qi, nourishing yin for moistening dryness and the like, and has a remarkable treatment effect on internal heat toxin abundant type mastitis, and relapse is not likely to occur after a patient is cured; besides, the traditional Chinese medicine preparation is mild in medicine property, free of toxic or side effects and high in safety.
Description
[technical field]
The present invention relates to pharmaceutical technology field, a kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis and preparation method thereof.
[technical background]
Mastitis refer to that the acute festering type of mammary gland infects, and are puerperal commonly encountered diseases, are one of reasons causing puerperal fever,
It is most commonly in nursing women, especially primipara.In recent years, along with change and the quickening of rhythm of life of people's mode of operation,
Mastitis sickness rate is in the trend risen year by year, and its sickness rate accounts for the first place of mastopathy.Acute simple mastitis initial stage general disease
Shape is the distending pain of breast, and local skin is red, swollen, hot, bitterly, and ill-defined scleroma is touched a tender spot more;Sometimes be also possible to
The whole body void shapes such as shiver with cold, high heat, headache, unable, arteries and veins is fast, and axillary lymph knot enlargement, tenderness;It is also possible to draw time serious
Sending out local tissue necrosis, liquefaction, the focus of infection differed in size mutually merges formation abscess.Therefore mastitis should be enhanced your vigilance,
Treated as soon as possible, otherwise, if remedy measures is the most capable or delay treatment makes the state of an illness increase the weight of further, it would be possible to cause being difficult to estimate
The serious consequence of amount.
At present, treatment mastitis medicine in the majority with Western medicine, as nodules of the breast relax, RUPIXIAO, inflammation can Kang Ling peaceful, newborn, anti-inflammation medicine etc.,
Although these Western medicine can play preferable therapeutic effect to a certain extent, but wherein most curative effects is only directed to eliminate surface
Pain symptom, cures the symptoms, not the disease, and easily recurs after treatment;Wherein also having some hormone medicines, taking for a long time can be to human body
Produce bigger toxic and side effects.The curative principle of Western medicine is generally placed upon treatment, and Chinese medicine is different from Western medicine, and Chinese medicine is by adjusting
Reason realizes curing, and treat the most thorough, but current clinic lacks in the treatment acute mastitis of with strong points, determined curative effect
Medicine.
[summary of the invention]
For posed problems above, the invention provides a kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis and preparation side thereof
Method, this Chinese medicine preparation is used for treating dominance of heat in the interior type mastitis and has that effect is notable, controls difficulty in relapse after healing, has no side effect,
Safe and reliable feature.
In order to realize above-mentioned purpose, the technical solution adopted in the present invention is:
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 10-20
Part, Radix Scrophulariae 9-15 part, Herba Scutellariae Barbatae 15-20 part, lotus 5-13 part, Rhizoma Fagopyri Dibotryis 18-22 part, Cyrtomium caryotideum (Wall.) Presl 2-7 part, Zhejiang
Bulbus Fritillariae Uninbracteatae 6-12 part, Fructus Akebiae 9-15 part, Saccharum Sinensis Roxb. root 6-15 part, Tremella 3-10 part.
Further, described Chinese medicine preparation includes the raw material of following weight portion: Herba Asplenii yunnanensis 12-18 part, Radix Scrophulariae 10-13 part,
Herba Scutellariae Barbatae 16-19 part, lotus 8-11 part, Rhizoma Fagopyri Dibotryis 19-21 part, Cyrtomium caryotideum (Wall.) Presl 4-6 part, Bulbus Fritillariae Thunbergii 8-10 part, August
Letter 11-14 part, Saccharum Sinensis Roxb. root 8-12 part, Tremella 5-7 part.
Further, described Chinese medicine preparation includes the raw material of following weight portion: Herba Asplenii yunnanensis 15 parts, Radix Scrophulariae 12 parts, half
18 parts of lotus, lotus 9 parts, Rhizoma Fagopyri Dibotryis 20 parts, Cyrtomium caryotideum (Wall.) Presl 5 parts, Bulbus Fritillariae Thunbergii 9 parts, Fructus Akebiae 12 parts, Saccharum Sinensis Roxb. root 10
Part, 6 parts of Tremella.
Further, the preparation method of described Chinese medicine preparation comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking of raw material gross weight 5-8 times
40-60min, intense fire turns slow fire boiling 30-40min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 3-5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20-30min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, granule,
Tablet, pill or capsule.
Instructions of taking: each take the Chinese medicine preparation that effective dose is 1-2g is daily 3 times, early, middle and late half little after meal
Time decoction being taken warmly, within 10 days, be a course for the treatment of, period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.
Chinese medicine details of the present invention is as follows:
Herba Asplenii yunnanensis: for the herb of Aspleniaceae plant Asplenium yunnanense, dry product.Bitter in the mouth, cold in nature.Return liver, bladder warp.
There is effect of heat-clearing and toxic substances removing, diuresis, lactogenesis.For high heat of catching a cold, cystitis, stranguria with blood, mastitis, galactostasis, breast
Rotten urine, orchitis.
Radix Scrophulariae: for the root of goatweed Radix Scrophulariae.Sweet in the mouth, hardship, salty, cold nature.Return lung meridian, stomach warp, kidney channel.Have clear
Hot removing heat from blood, nourishing YIN to lower pathogenic fire, relieving restlessness, effect of removing toxic substances.Controlling consumption of YIN caused by febrile disease, tongue unravels silk excessive thirst, sends out speckle, hectic fever due to YIN-deficiency consumptive fever, sleeps not night
Rather, spontaneous sweating, constipation, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula, maculae caused by violent heat pathogen, conjunctival congestion, diphtheria, skin ulcer are hindered in Tianjin
Poison.
Herba Scutellariae Barbatae: for the dry aerial parts of labiate Herba Scutellariae Barbatae.Acrid in the mouth, hardship, cold in nature.Return lung meridian, Liver Channel, kidney channel.
There is effect of heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice, have sore throat,
Lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.
Lotus: for the rhizome of zingiberaceous plant lotus.Acrid in the mouth, warm in nature.Return lung, Liver Channel.Have promoting blood flow to regulate menstruation, relieving cough and expelling phlegm,
Effect of subduing swelling and detoxicating.Control menoxenia, dysmenorrhea, scrofula, conjunctival congestion, sore throat, traumatic injury, old cough, carbuncle
Toxic swelling.
Rhizoma Fagopyri Dibotryis: for the dry rhizome of polygonaceae plant Rhizoma Fagopyri Dibotryis.Taste is micro-pungent, puckery, cool in nature.Return lung meridian.Have heat-clearing and toxic substances removing,
Invigorate blood circulation effect of eliminating carbuncle, expelling wind and removing dampness.Snake bite and insect sting.Main lung abscess, lung-heat cough with asthma, laryngopharynx swelling and pain, dysentery, rheumatism arthromyodynia,
Traumatic injury, carbuncle.
Cyrtomium caryotideum (Wall.) Presl: for the rhizome of Dryopteridaceae plant Cyrtomium caryotideum (Wall.) Presl.Bitter in the mouth, cold nature.Have removing toxic substances, invigorate blood circulation, diuretic
Effect.Control the tuberculosis of cervical lymph nodes, sore, edema, metrorrhagia, traumatic injury." Guizhou medical herbs ": promoting blood circulation to remove blood stasis, relieving stranguria by diuresis.
Control traumatic injury, edema.
Bulbus Fritillariae Thunbergii: for the bulb of liliaceous plant Bulbus Fritillariae Thunbergii.Bitter in the mouth, cold in nature.Return lung meridian, heart channel.There is removing heat-phlegm, dissipate
Effect of knot removing toxic substances.Control cough due to pathogenic wind-heat, lung abscess sore throat, scrofula, sore swollen toxin." book on Chinese herbal medicine is just ": control greatly lung abscess lung and wither, cough with asthma,
Spit blood, epistaxis, most mental disorder drops, and kind relieving stagnation, relieve the pain pain, and relieving distension is full, clearing away liver-fire, bright knowledge, except seasonal epidemic pathogens dysphoria with smothery sensation, jaundice
Stranguria with urinary obstruction, hematuria of having blood in stool;Relieving heat toxin, kills parasites and treats sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings, damp and hot malignant boil,
Anal fistula, incised wound is hemorrhage, burn pain, and than Bulbus Fritillariae Cirrhosae, the merit of clear fall, not less than several times.
Fructus Akebiae: for the seed of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae, dry product.Mildly bitter flavor, property is put down.Return Liver Channel,
Stomach warp.There is liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, effect of relieving restlessness diuresis.Treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, also Hakuri
Disease, lumbago, hypochondriac pain, hernia, dysmenorrhea, uterus drops." pharmacognosy ": promoting the circulation of QI, invigorates blood circulation, parasite killing, removing toxic substances, pain relieving.With
In diseases such as stomachache due to hyperactive liver-QI attacking the stomach, hypochondriac pain, menstrual pain." Shaanxi Chinese herbal medicine ": Shugan Yishen, invigorating the spleen and regulating the stomach.Control dyspepsia, stomachache,
Dysentery, hernia, uterus drops.
Saccharum Sinensis Roxb. root: for the Herb of dicotyledon medicine Maguireothamnus speciosus microcephaly cool larynx tea.Lightly seasoned, warm in nature.Return liver,spleen,kidney warp.
Have cold expelling dredging collateral, nourish blood, effect of preventing the attack (or recurrence) of malaria.Main malaria, affection of exogenous wind-cold, menoxenia, puerperal, galactostasis, dry
Cough, dermatitis rhus, trauma of fracturing.
Tremella: Mycophyta Tremellaceae Tremella plant Tremella is used as medicine with sporophore.Sweet in the mouth, light, property is put down.Return lung meridian, stomach through,
Kidney channel.There is effect of invigorating the lung and benefiting vital QI, nourishing YIN to relieve dryness.Empty for body after being ill, chronic cough of deficiency lung, sputum mixed with blood, metrorrhagia, stool
Constipated, hypertension, sclerosis of blood vessels.
The invention provides a kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis and preparation method thereof, compared with prior art,
Have the advantages that
The Chinese medicine preparation for the treatment of dominance of heat in the interior type mastitis provided by the present invention enters according to the pathogenesis of dominance of heat in the interior type mastitis
Row makes up a prescription, with Herba Asplenii yunnanensis, Radix Scrophulariae, Herba Scutellariae Barbatae, lotus, Rhizoma Fagopyri Dibotryis, Cyrtomium caryotideum (Wall.) Presl, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb.
Root, Tremella are primary raw material, wherein Herba Asplenii yunnanensis, Radix Scrophulariae, Herba Scutellariae Barbatae have heat-clearing and toxic substances removing, YIN nourishing lactogenesis, removing heat from blood relieving restlessness,
The effects such as dissipating blood stasis analgesic therapy;Lotus, Rhizoma Fagopyri Dibotryis, Cyrtomium caryotideum (Wall.) Presl, Bulbus Fritillariae Thunbergii can be invigorated blood circulation eliminating carbuncle, expelling wind and removing dampness;Fructus Akebiae, Saccharum Sinensis Roxb.
Root can soothing the liver nourish blood, regulating qi and dredging collateral, pain relieving;Tremella can nourshing Yin and drynsessmoistening prescription, invigorating the lung and benefiting vital QI.The most all medicine compatibilities, bring out the best in each other,
Play heat-clearing and toxic substances removing, eliminating carbuncle of invigorating blood circulation, liver-smoothing, qi-regulating, nourshing Yin and drynsessmoistening prescription effect altogether, can fundamentally treat dominance of heat in the interior type mastitis,
Evident in efficacy, control difficulty in relapse after healing, the property of medicine is gentle, and has no side effect, safe and reliable.
[detailed description of the invention]
The following examples can help those skilled in the art to be more completely understood by the present invention, but cannot limit by any way
The present invention processed.
Embodiment 1
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 10 parts,
Radix Scrophulariae 9 parts, Herba Scutellariae Barbatae 15 parts, lotus 5 parts, Rhizoma Fagopyri Dibotryis 18 parts, Cyrtomium caryotideum (Wall.) Presl 2 parts, Bulbus Fritillariae Thunbergii 6 parts, Fructus Akebiae 9
Part, Saccharum Sinensis Roxb. root 6 parts, 3 parts of Tremella.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 40min of raw material gross weight 5 times,
Intense fire turns slow fire boiling 40min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 3 times in residue medicinal residues, intense fire boils and turns slow fire boiling 30min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder or granule etc.
Dosage form.
Embodiment 2
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 12 parts,
Radix Scrophulariae 10 parts, Herba Scutellariae Barbatae 16 parts, lotus 8 parts, Rhizoma Fagopyri Dibotryis 19 parts, Cyrtomium caryotideum (Wall.) Presl 4 parts, Bulbus Fritillariae Thunbergii 8 parts, Fructus Akebiae
11 parts, Saccharum Sinensis Roxb. root 8 parts, 5 parts of Tremella.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 60min of raw material gross weight 8 times,
Intense fire turns slow fire boiling 30min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, tablet or ball
The dosage forms such as agent,.
Embodiment 3
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 15 parts,
Radix Scrophulariae 12 parts, Herba Scutellariae Barbatae 18 parts, lotus 9 parts, Rhizoma Fagopyri Dibotryis 20 parts, Cyrtomium caryotideum (Wall.) Presl 5 parts, Bulbus Fritillariae Thunbergii 9 parts, Fructus Akebiae
12 parts, Saccharum Sinensis Roxb. root 10 parts, 6 parts of Tremella.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 50min of raw material gross weight 6 times,
Intense fire turns slow fire boiling 35min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 4 times in residue medicinal residues, intense fire boils and turns slow fire boiling 25min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make granule, pill or
The dosage forms such as capsule,.
Embodiment 4
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 18 parts,
Radix Scrophulariae 13 parts, Herba Scutellariae Barbatae 19 parts, lotus 11 parts, Rhizoma Fagopyri Dibotryis 21 parts, Cyrtomium caryotideum (Wall.) Presl 6 parts, Bulbus Fritillariae Thunbergii 10 parts, August
14 parts of letter, Saccharum Sinensis Roxb. root 12 parts, 7 parts of Tremella.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 55min of raw material gross weight 7 times,
Intense fire turns slow fire boiling 40min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 30min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make the agent such as tablet or pill
Type,.
Embodiment 5
A kind of Chinese medicine preparation treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: Herba Asplenii yunnanensis 20 parts,
Radix Scrophulariae 15 parts, Herba Scutellariae Barbatae 20 parts, lotus 13 parts, Rhizoma Fagopyri Dibotryis 22 parts, Cyrtomium caryotideum (Wall.) Presl 7 parts, Bulbus Fritillariae Thunbergii 12 parts, Fructus Akebiae
15 parts, Saccharum Sinensis Roxb. root 15 parts, 10 parts of Tremella.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 45min of raw material gross weight 7 times,
Intense fire turns slow fire boiling 30min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 3 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make granule or capsule
Etc. dosage form,.
Clinical observation statistics
1, the object of observation:
Selecting dominance of heat in the interior type mastitis patient 200 example made a definite diagnosis to carry out clinical observation, cardinal symptom has: distending pain of the breast, heating,
Local skin is red and swollen, streak, sheet block tophus block, touches a tender spot substantially, and nipple is inaccessible or flows out yellow and purulent secretion,
Or with ipsilateral axillary lymphadenectasis etc..It is randomly divided into treatment group and matched group, treatment group 100 example, age 21-42 year,
28.1 years old mean age, the shortest person of the course of disease 1 month, elder 2 years;Matched group 100 example, age 22-43 year, average year
27.9 years old age, 1 first quarter moon of the shortest person of the course of disease, elder 2 years.Treatment group and matched group two groups of case ages, the course of disease, symptoms
Light and heavy degree is basically identical, without significant difference, has comparability.
2, Therapeutic Method
Treatment group: medicine of the present invention for oral administration, three times a day, each takes the medicine that effective dose is 1-2g, early, middle and late meal
Half an hour after warm water takes, and within 10 days, is a course for the treatment of, observes after taking 1-3 the course for the treatment of, and period of taking medicine withdraws other drug,
And avoid eating anything raw or cold, pungent, stimulate food.
Matched group: the medicine of the oral treatment dominance of heat in the interior type mastitis bought on the market (as nodules of the breast relaxes sheet, breast Kang Ling etc.),
Taking according to taking explanation, carry out Synchronous with treatment group, period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent,
The food stimulated.
4, treatment standard
Curing: General Symptoms disappears, lump dissipates, and physical recovery is normal, and body index recovers normal on inspection;Effective: complete
Body symptom disappears substantially, and local pain substantially alleviates, and body index recovers normal substantially on inspection;Effective: General Symptoms is basic
Disappearing, local pain has alleviated, on inspection body index part;Invalid: after medication, the symptom of patient has no improvement.
5, therapeutic outcome
Treatment group and matched group clinical treatment outcome are as shown in table 1:
Table 1 treatment group and matched group clinical treatment outcome
n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate (%) | |
Treatment group | 100 | 36 | 23 | 29 | 12 | 88 |
Matched group | 100 | 20 | 17 | 32 | 31 | 69 |
By the clinical treatment outcome of upper table 1 treatment group and matched group it can be seen that treatment group 100 example, take the present invention and treat heat
In poison after 1-3 the course for the treatment of of Chinese medicine preparation of Sheng type mastitis, curing 36 examples (accounting for total 36%), effective 23 examples (account for sum
23%), effective 29 examples (account for sum 29%), and invalid 12 examples, total effective rate is 88%;Matched group 100 example, takes at present
Commercially available treatment dominance of heat in the interior type mastitis medicament, synchronization carries out observing with treatment group, cures 20 examples (accounting for sum 20%),
Effective 17 examples (account for sum 17%), and effective 32 examples (account for sum 32%), and invalid 31 examples, total effective rate is 69%;It is visible,
Medicine of the present invention is used for treating dominance of heat in the interior type mastitis effect and is substantially better than matched group marketed drugs, and cure rate is high.
Claims (4)
1. the Chinese medicine preparation treating dominance of heat in the interior type mastitis, it is characterised in that described Chinese medicine preparation includes following weight portion
Raw material: Herba Asplenii yunnanensis 10-20 part, Radix Scrophulariae 9-15 part, Herba Scutellariae Barbatae 15-20 part, lotus 5-13 part, Rhizoma Fagopyri Dibotryis 18-22
Part, Cyrtomium caryotideum (Wall.) Presl 2-7 part, Bulbus Fritillariae Thunbergii 6-12 part, Fructus Akebiae 9-15 part, Saccharum Sinensis Roxb. root 6-15 part, Tremella 3-10 part.
2. the Chinese medicine preparation treating dominance of heat in the interior type mastitis as claimed in claim 1, it is characterised in that described Chinese medicine preparation bag
Include the raw material of following weight portion: Herba Asplenii yunnanensis 12-18 part, Radix Scrophulariae 10-13 part, Herba Scutellariae Barbatae 16-19 part, lotus 8-11 part,
Rhizoma Fagopyri Dibotryis 19-21 part, Cyrtomium caryotideum (Wall.) Presl 4-6 part, Bulbus Fritillariae Thunbergii 8-10 part, Fructus Akebiae 11-14 part, Saccharum Sinensis Roxb. root 8-12 part, silver
Ear 5-7 part.
3. the Chinese medicine preparation treating dominance of heat in the interior type mastitis as claimed in claim 2, it is characterised in that described Chinese medicine preparation bag
Include the raw material of following weight portion: Herba Asplenii yunnanensis 15 parts, Radix Scrophulariae 12 parts, Herba Scutellariae Barbatae 18 parts, lotus 9 parts, Rhizoma Fagopyri Dibotryis 20
Part, Cyrtomium caryotideum (Wall.) Presl 5 parts, Bulbus Fritillariae Thunbergii 9 parts, Fructus Akebiae 12 parts, Saccharum Sinensis Roxb. root 10 parts, 6 parts of Tremella.
4. the preparation method of the Chinese medicine preparation of the treatment dominance of heat in the interior type mastitis as described in claim 1-3 is arbitrary, its feature exists
Comprise the following steps in described preparation method:
1) described raw material is picked according to above-mentioned weight portion;
2) by step 1) raw material that picked cleans and dries, then Herba Asplenii yunnanensis, Herba Scutellariae Barbatae, Cyrtomium caryotideum (Wall.) Presl, Tremella are broken
It is broken to length and is less than 2cm, Radix Scrophulariae, lotus, Rhizoma Fagopyri Dibotryis, Bulbus Fritillariae Thunbergii, Fructus Akebiae, Saccharum Sinensis Roxb. root are cut into thickness less than 0.5cm's
Thin slice, then will above process after raw material mixing, obtain mixing crude drug;
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking of raw material gross weight 5-8 times
40-60min, intense fire turns slow fire boiling 30-40min after boiling, filter, taking liquid I, and residue medicinal residues retain;
4) toward step 3) filter the water adding raw material gross weight 3-5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20-30min,
Filter, taking liquid II;
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder,
Obtain water extract dry powder;
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, granule,
Tablet, pill or capsule.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103156985A (en) * | 2013-03-16 | 2013-06-19 | 武玉丽 | Traditional Chinese medicine composition for treating cyclomastopathy |
CN103191370A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Medicine composite for treating mastitis and preparation method and application of medicine composite |
CN104398975A (en) * | 2014-11-13 | 2015-03-11 | 高宏 | Traditional Chinese medicinal preparation for treating fibroadenoma of breast and preparation method thereof |
CN104689100A (en) * | 2015-02-02 | 2015-06-10 | 王英梅 | Traditional Chinese medicine for treatment of galactostasis and mastitis complications |
-
2016
- 2016-04-27 CN CN201610268436.8A patent/CN105727242A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103156985A (en) * | 2013-03-16 | 2013-06-19 | 武玉丽 | Traditional Chinese medicine composition for treating cyclomastopathy |
CN103191370A (en) * | 2013-04-10 | 2013-07-10 | 成都中医药大学 | Medicine composite for treating mastitis and preparation method and application of medicine composite |
CN104398975A (en) * | 2014-11-13 | 2015-03-11 | 高宏 | Traditional Chinese medicinal preparation for treating fibroadenoma of breast and preparation method thereof |
CN104689100A (en) * | 2015-02-02 | 2015-06-10 | 王英梅 | Traditional Chinese medicine for treatment of galactostasis and mastitis complications |
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