CN105770833A - Traditional Chinese medicine for treating mastitis due to internal heat toxins and preparation method for traditional Chinese medicine - Google Patents

Traditional Chinese medicine for treating mastitis due to internal heat toxins and preparation method for traditional Chinese medicine Download PDF

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CN105770833A
CN105770833A CN201610269039.2A CN201610269039A CN105770833A CN 105770833 A CN105770833 A CN 105770833A CN 201610269039 A CN201610269039 A CN 201610269039A CN 105770833 A CN105770833 A CN 105770833A
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radix
chinese medicine
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郑耀玲
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10—Bryophyta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/86—Violaceae (Violet family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention relates to a traditional Chinese medicine for treating mastitis due to internal heat toxins and a preparation method for the traditional Chinese medicine, and belongs to the technical field of medicines. The traditional Chinese medicine comprises the following raw materials in parts by weight: 10-15 parts of haplocladium microphyllum, 15-20 parts of herba violae, 8-16 parts of cucumber root, 3-10 parts of radix platycodonis, 8-14 parts of zingiber mioga, 13-17 parts of rhizoma fagopyri dibotryis, 16-24 parts of beach morningglory herb, 4-10 parts of radix paeoniae rubra, 6-15 parts of folium citrus reticulatae, 10-20 parts of radix polygoni multifiori and 6-12 parts of radix polygonati officinalis. The traditional Chinese medicine has the effects of clearing heat and toxins, activating blood for eliminating carbuncle, soothing the liver for regulating vital energy, nourishing yin for moistening dryness and the like, is remarkable in curative effect for the mastitis due to the internal heat toxins, enables the mastitis due to the internal heat toxins to difficultly relapse after patients are cured, and is mild in medicine property, free of any toxic or side effect and high in safety.

Description

A kind of Chinese medicine treating dominance of heat in the interior type mastitis and preparation method thereof
[technical field]
The present invention relates to pharmaceutical technology field, a kind of Chinese medicine treating dominance of heat in the interior type mastitis and preparation method thereof.
[technical background]
Mastitis refer to that the acute festering type of mammary gland infects, and are puerperal commonly encountered diseases, are one of reasons causing puerperal fever, It is most commonly in nursing women, especially primipara.In recent years, along with change and the quickening of rhythm of life of people's mode of operation, Mastitis sickness rate is in the trend risen year by year, and its sickness rate accounts for the first place of mastopathy.Acute simple mastitis initial stage general disease Shape is the distending pain of breast, and local skin is red, swollen, hot, bitterly, and ill-defined scleroma is touched a tender spot more；Sometimes be also possible to The whole body void shapes such as shiver with cold, high heat, headache, unable, arteries and veins is fast, and axillary lymph knot enlargement, tenderness；It is also possible to draw time serious Sending out local tissue necrosis, liquefaction, the focus of infection differed in size mutually merges formation abscess.Therefore mastitis should be enhanced your vigilance, Treated as soon as possible, otherwise, if remedy measures is the most capable or delay treatment makes the state of an illness increase the weight of further, it would be possible to cause being difficult to estimate The serious consequence of amount.
At present, treatment mastitis medicine in the majority with Western medicine, as nodules of the breast relax, RUPIXIAO, inflammation can Kang Ling peaceful, newborn, anti-inflammation medicine etc., Although these Western medicine can play preferable therapeutic effect to a certain extent, but wherein most curative effects is only directed to eliminate surface Pain symptom, cures the symptoms, not the disease, and easily recurs after treatment；Wherein also having some hormone medicines, taking for a long time can be to human body Produce bigger toxic and side effects.The curative principle of Western medicine is generally placed upon treatment, and Chinese medicine is different from Western medicine, and Chinese medicine is by adjusting Reason realizes curing, and treat the most thorough, but current clinic lacks in the treatment acute mastitis of with strong points, determined curative effect Medicine.
[summary of the invention]
For posed problems above, the invention provides a kind of Chinese medicine treating dominance of heat in the interior type mastitis and preparation method thereof, This Chinese medicine is used for treating dominance of heat in the interior type mastitis and has that effect is notable, controls difficulty in relapse after healing, has no side effect, safe and reliable Feature.
In order to realize above-mentioned purpose, the technical solution adopted in the present invention is:
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 10-15 part, Herba Violae 15-20 part, Radix Cucumidis sativi 8-16 part, Radix Platycodonis 3-10 part, lotus 8-14 part, Rhizoma Fagopyri Dibotryis 13-17 part, Herba Ipomoeae Pes-Capraes 16-24 Part, Radix Paeoniae Rubra 4-10 part, Folium Citri tangerinae 6-15 part, Radix Polygoni Multiflori 10-20 part, Rhizoma Polygonati Odorati 6-12 part.
Further, described Chinese medicine includes the raw material of following weight portion: point leaf little plumage moss 12-14 part, Herba Violae 17-19 part, Huang Melon root 10-14 part, Radix Platycodonis 5-7 part, lotus 10-12 part, Rhizoma Fagopyri Dibotryis 14-16 part, Herba Ipomoeae Pes-Capraes 18-22 part, Radix Paeoniae Rubra 5-7 Part, Folium Citri tangerinae 9-13 part, Radix Polygoni Multiflori 13-16 part, Rhizoma Polygonati Odorati 8-13 part.
Further, described Chinese medicine includes the raw material of following weight portion: point leaf little plumage moss 13 parts, Herba Violae 18 parts, Radix Cucumidis sativi 12 Part, Radix Platycodonis 6 parts, lotus 11 parts, Rhizoma Fagopyri Dibotryis 15 parts, Herba Ipomoeae Pes-Capraes 19 parts, Radix Paeoniae Rubra 6 parts, Folium Citri tangerinae 10 parts, Radix Polygoni Multiflori 15 Part, Rhizoma Polygonati Odorati 10 parts.
Further, the preparation method of described Chinese medicine comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking of raw material gross weight 5-8 times 40-60min, intense fire turns slow fire boiling 30-40min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 3-5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20-30min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, granule, Tablet, pill or capsule.
Instructions of taking: each taking the effective dose of the present invention is the Chinese medicine of 1-2g, daily 3 times, early, middle and late after meal half Hour decoction being taken warmly, 10 days is a course for the treatment of, and period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, the food that stimulates.
Chinese medicine details of the present invention is as follows:
Point leaf little plumage moss: for the plant of Yu Xian section plant spire little plumage moss.Bitter in the mouth, pungent, cool in nature.There is the merit of heat-clearing and toxic substances removing Effect.Main acute tonsillitis, mastitis, erysipelas, furuncle and phyma, upper respiratory tract infection, pneumonia, otitis media, cystitis, urethra Inflammation, adnexitis, puerperal infection, insect bite high heat.
Herba Violae: for the dry herb of Violaceae Chinese violet.Bitter in the mouth, pungent, cold in nature.GUIXIN warp, Liver Channel.There is heat clearing away Removing toxic substances, effect of removing heat from blood detumescence.It is mainly used to furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.
Radix Cucumidis sativi: for the root of cucurbitaceous plant Fructus Cucumidis sativi.Bitter in the mouth, micro-sweet, cool in nature.Return stomach, large intestine channel.Have heat clearing away, dampness removing, Effect of removing toxic substances.Main damp-heat dysentery, jaundice, sore swollen toxin, discharging ear.
Radix Platycodonis: for the root of Campanulaceae Radix Platycodonis.Bitter in the mouth, pungent, property is put down.Return lung meridian, stomach warp.There is out lung qi dispersing gas, eliminate the phlegm Effect of evacuation of pus.Controlling exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery is suffered from abdominal pain." Japan hanako materia medica ": under All gas, only cramp caused by acute vomiting and diarrhea, trusted subordinate's distending pain, to mend five kinds of over strain, foster the spirit of nobility, evil removing wards off temperature, qi-restoratives expectorant, broken abdominal mass, evacuation of pus of nourishing blood, Mend internal hemorrhage due to trauma and sore throat.
Lotus: for the rhizome of zingiberaceous plant lotus.Acrid in the mouth, warm in nature.Return lung, Liver Channel.Have promoting blood flow to regulate menstruation, relieving cough and expelling phlegm, Effect of subduing swelling and detoxicating.Control menoxenia, dysmenorrhea, scrofula, conjunctival congestion, sore throat, traumatic injury, old cough, carbuncle Toxic swelling.
Rhizoma Fagopyri Dibotryis: for the dry rhizome of polygonaceae plant Rhizoma Fagopyri Dibotryis.Taste is micro-pungent, puckery, cool in nature.Return lung meridian.Have heat-clearing and toxic substances removing, Invigorate blood circulation effect of eliminating carbuncle, expelling wind and removing dampness.Snake bite and insect sting.Main lung abscess, lung-heat cough with asthma, laryngopharynx swelling and pain, dysentery, rheumatism arthromyodynia, Traumatic injury, carbuncle.
Herba Ipomoeae Pes-Capraes: for the herb of convolvulaceous plant king crab rattan.Acrid in the mouth is bitter, cold nature.Enter liver, spleen two warp.Have dispel the wind, dehumidify, Eliminating carbuncle, effect of eliminating stagnation.Dispelling the wind and dampness pathogens arthralgia pain, carbuncle, toxic swelling, treat skin ulcer, anal fistula.
Radix Paeoniae Rubra: for ranunculaceae plant Radix Paeoniae or the dry root of river Radix Paeoniae Rubra.Bitter in the mouth, cold nature.Return Liver Channel.Have clots absorbing, pain relieving, Clearing away heat and cooling blood, effect of detumescence.Controlling the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, mesh Red, carbuncle." property of medicine opinion ": control pathogen of the lung gas, abdominal pain, vim and vigour are gathered, and logical a surname's internal organs gather around gas, control evil pain deteriorated blood, time main Disease bone heat, strong the five internal organs, the kidney invigorating gas, control trusted subordinate's heavily fortified point swollen, married woman's blood closes obstructed, repercussive blood, can lose pus." Japan hanako materia medica ": Control wind and mend labor, all sick and antenatal rear all diseases of main woman, Tong Yueshui, relieving restlessness of bringing down a fever, QI invigorating, the hot disease of sky row, pestilence miasma mania and irritation, Married woman's blood is transported, and hemorrhoidal hamorrhage rushes down blood；Hemorrhoid complicated by anal fistula, carbuncle on the back, skin ulcer scabies, headache, improving eyesight, conjunctival congestion, bulbar conjunctiva polyp." the southern regions of the Yunnan Province book on Chinese herbal medicine ": purgation of spleen excess Fire, sending down the abnormal ascending QI, promoting the circulation of blood, removing blood stasis with potent drugs, dissipate clot, only stomachache, moves back heat in blood, attacks ulcerative carbuncle, control mange.
Folium Citri tangerinae: for the leaf of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae, dry product.Bitter in the mouth is pungent, and property is put down.Have soothing the liver, OK Gas, reduce phlegm, subside a swelling poison effect.Control hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.
Radix Polygoni Multiflori: for the dried root of polygonum multiflorum thunb.Bitter in the mouth, sweet, puckery, warm in nature.Return Liver Channel, heart channel, kidney channel. There is tonifying liver, kidney tonifying, effect of nourishing blood, dispeling the wind.Controlling hepatic and renal YIN deficiency, sending out must be the whitest, and blood deficiency is dizzy, and waist knee joint is weak, muscles and bones Ache, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Radix Polygoni Multiflori Preparata invigorating the liver and kidney, benefit Essence and blood, crow beard and hair, strengthening bone and muscle；For vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, neurasthenia, high blood Fat disease.
Rhizoma Polygonati Odorati: for the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati.Sweet in the mouth, property is put down.Enter lung meridian, stomach warp.Have yin nourishing, moisturize, Relieving restlessness, the effect quenched the thirst.Controlling calentura the moon wound, excessive thirst of coughing, deficient fever, rapid digestion of food is the most hungry, frequent micturition." Guangxi Chinese medicinal herbal ": Nourishing YIN and clearing away lung-heat is moisturized.Control the deficiency of YIN, hyperhidrosis, cough caused by dryness, consumptive lung disease.
The invention provides a kind of Chinese medicine treating dominance of heat in the interior type mastitis and preparation method thereof, compared with prior art, have Following beneficial effect:
The pathogenesis that the Chinese medicine for the treatment of dominance of heat in the interior type mastitis provided by the present invention emits according to dominance of heat in the interior type mastitis is carried out Make up a prescription, with point leaf little plumage moss, Herba Violae, Radix Cucumidis sativi, Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Herba Ipomoeae Pes-Capraes, Radix Paeoniae Rubra, Folium Citri tangerinae, Radix Polygoni Multiflori, Rhizoma Polygonati Odorati is primary raw material, and wherein point leaf little plumage moss, Herba Violae, Radix Cucumidis sativi, Radix Platycodonis have the detumescence of heat-clearing and toxic substances removing, removing heat from blood, evacuation of pus of eliminating the phlegm Etc. effect；Lotus, Rhizoma Fagopyri Dibotryis, Herba Ipomoeae Pes-Capraes, Radix Paeoniae Rubra can be invigorated blood circulation eliminating carbuncle, removing obstruction for relieving pain, expelling wind and removing dampness；Folium Citri tangerinae, Radix Polygoni Multiflori can Soothing the liver reduce phlegm, circulation of qi promoting is nourished blood；Rhizoma Polygonati Odorati can be nourshing Yin and drynsessmoistening prescription.The most all medicine compatibilities, bring out the best in each other, and play heat-clearing and toxic substances removing altogether, invigorating blood circulation disappears Carbuncle, liver-smoothing, qi-regulating, nourshing Yin and drynsessmoistening prescription effect, can fundamentally treat dominance of heat in the interior type mastitis, evident in efficacy, after healing not Easily recurrence, the property of medicine is gentle, and has no side effect, safe and reliable.
[detailed description of the invention]
The following examples can help those skilled in the art to be more completely understood by the present invention, but cannot limit by any way The present invention processed.
Embodiment 1
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 10 parts, Herba Violae 15 parts, Radix Cucumidis sativi 8 parts, Radix Platycodonis 3 parts, lotus 8 parts, Rhizoma Fagopyri Dibotryis 13 parts, Herba Ipomoeae Pes-Capraes 16 parts, Radix Paeoniae Rubra 4 parts, Folium Citri tangerinae 6 Part, Radix Polygoni Multiflori 10 parts, Rhizoma Polygonati Odorati 6 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 40min of raw material gross weight 5 times, Intense fire turns slow fire boiling 30min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 3 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder or granule etc. Dosage form.
Embodiment 2
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 12 parts, Herba Violae 17 parts, Radix Cucumidis sativi 10 parts, Radix Platycodonis 5 parts, lotus 10 parts, Rhizoma Fagopyri Dibotryis 14 parts, Herba Ipomoeae Pes-Capraes 18 parts, Radix Paeoniae Rubra 5 parts, Folium Citri tangerinae 9 parts, Radix Polygoni Multiflori 13 parts, Rhizoma Polygonati Odorati 8 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 50min of raw material gross weight 6 times, Intense fire turns slow fire boiling 35min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 4 times in residue medicinal residues, intense fire boils and turns slow fire boiling 25min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, tablet or ball The dosage forms such as agent.
Embodiment 3
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 13 parts, Herba Violae 18 parts, Radix Cucumidis sativi 12 parts, Radix Platycodonis 6 parts, lotus 11 parts, Rhizoma Fagopyri Dibotryis 15 parts, Herba Ipomoeae Pes-Capraes 19 parts, Radix Paeoniae Rubra 6 parts, Folium Citri tangerinae 10 parts, Radix Polygoni Multiflori 15 parts, Rhizoma Polygonati Odorati 10 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 45min of raw material gross weight 7 times, Intense fire turns slow fire boiling 35min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 25min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make granule, pill or Capsule.
Embodiment 4
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 14 parts, Herba Violae 19 parts, Radix Cucumidis sativi 14 parts, Radix Platycodonis 7 parts, lotus 12 parts, Rhizoma Fagopyri Dibotryis 16 parts, Herba Ipomoeae Pes-Capraes 22 parts, Radix Paeoniae Rubra 7 parts, Folium Citri tangerinae 13 parts, Radix Polygoni Multiflori 16 parts, Rhizoma Polygonati Odorati 13 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 55min of raw material gross weight 7 times, Intense fire turns slow fire boiling 30min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 30min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make the agent such as tablet or pill Type.
Embodiment 5
A kind of Chinese medicine treating dominance of heat in the interior type mastitis, it includes the raw material of following weight portion: point leaf little plumage moss 15 parts, Herba Violae 20 parts, Radix Cucumidis sativi 16 parts, Radix Platycodonis 10 parts, lotus 14 parts, Rhizoma Fagopyri Dibotryis 17 parts, Herba Ipomoeae Pes-Capraes 24 parts, Radix Paeoniae Rubra 10 parts, Fructus Citri tangerinae 15 parts of leaf, Radix Polygoni Multiflori 20 parts, Rhizoma Polygonati Odorati 12 parts.Concrete preparation method comprises the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking 60min of raw material gross weight 8 times, Intense fire turns slow fire boiling 40min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 4 times in residue medicinal residues, intense fire boils and turns slow fire boiling 30min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make granule or capsule Etc. dosage form.
Clinical observation statistics
1, the object of observation:
Selecting dominance of heat in the interior type mastitis patient 200 example made a definite diagnosis to carry out clinical observation, cardinal symptom has: distending pain of the breast, heating, Local skin is red and swollen, streak, sheet block tophus block, touches a tender spot substantially, and nipple is inaccessible or flows out yellow and purulent secretion, Or with ipsilateral axillary lymphadenectasis etc..It is randomly divided into treatment group and matched group, treatment group 100 example, age 20-41 year, 27.5 years old mean age, the shortest person of the course of disease 2 months, elder 2 years；Matched group 100 example, age 21-42 year, average year 27.8 years old age, 1 first quarter moon of the shortest person of the course of disease, elder 2 years.Treatment group and matched group two groups of case ages, the course of disease, symptoms Light and heavy degree is basically identical, without significant difference, has comparability.
2, Therapeutic Method
Treatment group: medicine of the present invention for oral administration, three times a day, each takes the medicine that effective dose is 1-2g, early, middle and late meal Half an hour after warm water takes, and within 10 days, is a course for the treatment of, observes after taking 1-3 the course for the treatment of, and period of taking medicine withdraws other drug, And avoid eating anything raw or cold, pungent, stimulate food.
Matched group: the medicine of the oral treatment dominance of heat in the interior type mastitis bought on the market (as nodules of the breast relaxes sheet, breast Kang Ling etc.), Taking according to taking explanation, carry out Synchronous with treatment group, period of taking medicine withdraws other drug, and avoid eating anything raw or cold, pungent, The food stimulated.
4, treatment standard
Curing: General Symptoms disappears, lump dissipates, and physical recovery is normal, and body index recovers normal on inspection；Effective: complete Body symptom disappears substantially, and local pain substantially alleviates, and body index recovers normal substantially on inspection；Effective: General Symptoms is basic Disappearing, local pain has alleviated, on inspection body index part；Invalid: after medication, the symptom of patient has no improvement.
5, therapeutic outcome
Treatment group and matched group clinical treatment outcome are as shown in table 1:
Table 1 treatment group and matched group clinical treatment outcome
n Recovery from illness Effective Effectively Invalid Total effective rate (%)
Treatment group 100 37 23 29 11 89
Matched group 100 22 16 33 29 71
By the clinical treatment outcome of upper table 1 treatment group and matched group it can be seen that treatment group 100 example, take the present invention and treat heat In poison after 1-3 the course for the treatment of of Chinese medicine of Sheng type mastitis, curing 37 examples (accounting for sum 37%), effective 23 examples (account for total 23%), Effective 29 examples (account for sum 29%), and invalid 11 examples, total effective rate is 89%；Matched group 100 example, takes presently commercially available controlling Treat dominance of heat in the interior type mastitis medicament, synchronization carry out observing with treatment group, cure 22 examples (accounting for sum 22%), effective 16 Example (accounts for sum 16%), and effective 33 examples (account for sum 33%), and invalid 29 examples, total effective rate is 71%；Visible, the present invention Chinese medicine is used for treating dominance of heat in the interior type mastitis effect and is substantially better than matched group marketed drugs, and cure rate is high.

Claims (4)

1. the Chinese medicine treating dominance of heat in the interior type mastitis, it is characterised in that described Chinese medicine includes the raw material of following weight portion: point Leaf little plumage moss 10-15 part, Herba Violae 15-20 part, Radix Cucumidis sativi 8-16 part, Radix Platycodonis 3-10 part, lotus 8-14 part, Rhizoma Fagopyri Dibotryis 13-17 part, Herba Ipomoeae Pes-Capraes 16-24 part, Radix Paeoniae Rubra 4-10 part, Folium Citri tangerinae 6-15 part, Radix Polygoni Multiflori 10-20 part, Rhizoma Polygonati Odorati 6-12 part.
2. the Chinese medicine treating dominance of heat in the interior type mastitis as claimed in claim 1, it is characterised in that described Chinese medicine includes following weight The raw material of amount part: point leaf little plumage moss 12-14 part, Herba Violae 17-19 part, Radix Cucumidis sativi 10-14 part, Radix Platycodonis 5-7 part, lotus 10-12 Part, Rhizoma Fagopyri Dibotryis 14-16 part, Herba Ipomoeae Pes-Capraes 18-22 part, Radix Paeoniae Rubra 5-7 part, Folium Citri tangerinae 9-13 part, Radix Polygoni Multiflori 13-16 part, Rhizoma Polygonati Odorati 8-13 part.
3. the Chinese medicine treating dominance of heat in the interior type mastitis as claimed in claim 2, it is characterised in that described Chinese medicine includes following weight The raw material of amount part: point leaf little plumage moss 13 parts, Herba Violae 18 parts, Radix Cucumidis sativi 12 parts, Radix Platycodonis 6 parts, lotus 11 parts, Rhizoma Fagopyri Dibotryis 15 parts, Herba Ipomoeae Pes-Capraes 19 parts, Radix Paeoniae Rubra 6 parts, Folium Citri tangerinae 10 parts, Radix Polygoni Multiflori 15 parts, Rhizoma Polygonati Odorati 10 parts.
4. the preparation method of the Chinese medicine of the treatment dominance of heat in the interior type mastitis as described in claim 1-3 is arbitrary, it is characterised in that institute State preparation method to comprise the following steps:
1) described raw material is picked according to above-mentioned weight portion；
2) by step 1) raw material that picked cleans and dries, then by little for point leaf plumage moss, Herba Violae, Radix Cucumidis sativi, Herba Ipomoeae Pes-Capraes, Fructus Citri tangerinae Radix Platycodonis, lotus, Rhizoma Fagopyri Dibotryis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, less than 2cm, are cut into thickness less than 0.5cm's by leaf, the disconnected length that is broken to of Rhizoma Polygonati Odorati Thin slice, the raw material mixing after then processing above, obtain mixing crude drug；
3) by step 3) the mixing crude drug of gained puts in decoction container, adds the water soaking of raw material gross weight 5-8 times 40-60min, intense fire turns slow fire boiling 30-40min after boiling, filter, taking liquid I, and residue medicinal residues retain；
4) toward step 3) filter the water adding raw material gross weight 3-5 times in residue medicinal residues, intense fire boils and turns slow fire boiling 20-30min, Filter, taking liquid II；
5) combining step 3) gained medicinal liquid I and step 4) gained medicinal liquid II, obtain merging medicinal liquid, be then spray dried to powder, Obtain water extract dry powder；
6) toward step 5) the water extract dry powder of gained adds pharmaceutically acceptable adjuvant, make powder, granule, Tablet, pill or capsule.
CN201610269039.2A 2016-04-27 2016-04-27 Traditional Chinese medicine for treating mastitis due to internal heat toxins and preparation method for traditional Chinese medicine Pending CN105770833A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361894A (en) * 2008-08-29 2009-02-11 蒋保珍 Medicine for treating mastitis
CN102018912A (en) * 2009-09-23 2011-04-20 吴云霞 Chinese herbal preparation for treating acute mastitis
CN103142733B (en) * 2013-03-05 2014-06-25 刘风荣 Chinese medicine composition for treating upper respiratory infection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101361894A (en) * 2008-08-29 2009-02-11 蒋保珍 Medicine for treating mastitis
CN102018912A (en) * 2009-09-23 2011-04-20 吴云霞 Chinese herbal preparation for treating acute mastitis
CN103142733B (en) * 2013-03-05 2014-06-25 刘风荣 Chinese medicine composition for treating upper respiratory infection

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Application publication date: 20160720