CN105722831B - 哒嗪酮化合物及其用途 - Google Patents
哒嗪酮化合物及其用途 Download PDFInfo
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- CN105722831B CN105722831B CN201480061772.4A CN201480061772A CN105722831B CN 105722831 B CN105722831 B CN 105722831B CN 201480061772 A CN201480061772 A CN 201480061772A CN 105722831 B CN105722831 B CN 105722831B
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
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- A61K31/50—Pyridazines; Hydrogenated pyridazines
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361877171P | 2013-09-12 | 2013-09-12 | |
| US61/877,171 | 2013-09-12 | ||
| PCT/US2014/055018 WO2015038660A1 (en) | 2013-09-12 | 2014-09-10 | Pyridazinone compounds and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105722831A CN105722831A (zh) | 2016-06-29 |
| CN105722831B true CN105722831B (zh) | 2019-08-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| PE20151433A1 (es) | 2012-12-21 | 2015-10-16 | Alios Biopharma Inc | Nucleosidos sustituidos, nucleotidos y analogos de los mismos |
| EA037949B1 (ru) * | 2013-09-12 | 2021-06-10 | Янссен Байофарма, Инк. | Азапиридоновые соединения и их применение |
| EP3268368A4 (en) | 2015-03-11 | 2018-11-14 | Alios Biopharma, Inc. | Aza-pyridone compounds and uses thereof |
| RU2712275C9 (ru) | 2015-04-28 | 2020-03-19 | Сионоги Энд Ко., Лтд. | Замещенные полициклические производные пиридона и их пролекарства |
| BR112018011103A2 (pt) | 2015-12-15 | 2018-11-21 | Shionogi & Co., Ltd. | medicamento para tratar a gripe caracterizada por combinação de inibidor de endonuclease dependente de cap e de fármaco antigripe |
| JP6918819B2 (ja) | 2016-03-08 | 2021-08-11 | ノバルティス アーゲー | オルトミクソウイルス感染の処置に有用な三環式化合物 |
| US10183945B2 (en) | 2016-03-10 | 2019-01-22 | Alios Biopharma, Inc. | Method of preparing AZA-pyridone compounds |
| AU2017310774B2 (en) | 2016-08-10 | 2023-01-19 | Shionogi & Co., Ltd. | Substituted polycyclic pyridone derivative and pharmaceutical composition containing prodrug thereof |
| JOP20170169A1 (ar) | 2016-08-29 | 2019-01-30 | Novartis Ag | مركبات بيريدازين ثلاثية الحلقة مندمجة تفيد في علاج العدوى بفيروس أورثوميكسو |
| AU2019227250B2 (en) | 2018-02-28 | 2021-11-04 | Novartis Ag | 10-(di(phenyl)methyl)-4-hydroxy-8,9,9a,10-tetrahydro-7H-pyrrolo[1 ',2':4,5]pyrazino[1,2-b]pyridazine-3,5-dione derivatives and related compounds as inhibitors of the orthomyxovirus replication for treating influenza |
| MX2021004182A (es) | 2018-10-10 | 2021-09-08 | Janssen Biopharma Inc | Inhibidores macrocíclicos de endonucleasa de la gripe. |
| US11718612B2 (en) | 2019-09-06 | 2023-08-08 | Board Of Regents, The University Of Texas System | Inhibitors of receptor interacting protein kinase I for the treatment of disease |
| IL291665B2 (en) | 2019-09-27 | 2025-07-01 | Univ Texas | Inhibitors of receptor interacting protein kinase i for the treatment of disease |
| WO2021108198A1 (en) * | 2019-11-26 | 2021-06-03 | Board Of Regents, The University Of Texas System | Inhibitors of receptor interacting protein kinase i for the treatment of disease |
| WO2025244119A1 (ja) * | 2024-05-24 | 2025-11-27 | 住友化学株式会社 | ピリダジン誘導体及びそれを含有する組成物 |
| CN118546389B (zh) * | 2024-07-29 | 2024-10-15 | 陕西理工大学 | 哒嗪氢键骨架荧光传感材料及其制备方法和应用 |
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- 2014-09-10 JP JP2016542074A patent/JP6360176B2/ja not_active Expired - Fee Related
- 2014-09-10 CA CA2922943A patent/CA2922943A1/en not_active Abandoned
- 2014-09-10 AU AU2014318837A patent/AU2014318837B2/en not_active Ceased
- 2014-09-10 HK HK16113675.7A patent/HK1225382A1/zh unknown
- 2014-09-10 HR HRP20190822TT patent/HRP20190822T1/hr unknown
- 2014-09-10 DK DK14843298.2T patent/DK3030549T3/da active
- 2014-09-10 US US15/021,073 patent/US10364226B2/en active Active
- 2014-09-10 EP EP14843298.2A patent/EP3030549B8/en active Active
- 2014-09-10 ES ES14843298T patent/ES2724581T3/es active Active
- 2014-09-10 LT LTEP14843298.2T patent/LT3030549T/lt unknown
- 2014-09-10 SI SI201431180T patent/SI3030549T1/sl unknown
- 2014-09-10 KR KR1020167008927A patent/KR102286860B1/ko not_active Expired - Fee Related
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- 2014-09-10 CN CN201480061772.4A patent/CN105722831B/zh not_active Expired - Fee Related
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| KR102286860B1 (ko) | 2021-08-05 |
| EP3030549A4 (en) | 2017-03-15 |
| CN105722831A (zh) | 2016-06-29 |
| EA201690371A1 (ru) | 2016-08-31 |
| SI3030549T1 (sl) | 2019-08-30 |
| AU2014318837A1 (en) | 2016-03-24 |
| HK1225382A1 (zh) | 2017-09-08 |
| EA034868B1 (ru) | 2020-03-31 |
| HRP20190822T1 (hr) | 2019-08-23 |
| MX2016003135A (es) | 2017-07-11 |
| NZ717586A (en) | 2021-09-24 |
| IL244434A0 (en) | 2016-04-21 |
| LT3030549T (lt) | 2019-06-25 |
| DK3030549T3 (da) | 2019-05-13 |
| KR20160052683A (ko) | 2016-05-12 |
| IL244434B (en) | 2020-09-30 |
| PH12016500492B1 (en) | 2016-05-16 |
| EP3030549A1 (en) | 2016-06-15 |
| EP3030549B8 (en) | 2019-04-10 |
| JP2016530315A (ja) | 2016-09-29 |
| AU2014318837B2 (en) | 2019-05-30 |
| HUE043349T2 (hu) | 2019-08-28 |
| EP3030549B1 (en) | 2019-02-20 |
| US20160221963A1 (en) | 2016-08-04 |
| MX370085B (es) | 2019-11-29 |
| US10364226B2 (en) | 2019-07-30 |
| CA2922943A1 (en) | 2015-03-19 |
| WO2015038660A1 (en) | 2015-03-19 |
| PH12016500492A1 (en) | 2016-05-16 |
| ES2724581T3 (es) | 2019-09-12 |
| JP6360176B2 (ja) | 2018-07-18 |
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