CN105664017A - 球麻五窍喷雾剂系列的制备方法 - Google Patents

球麻五窍喷雾剂系列的制备方法 Download PDF

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CN105664017A
CN105664017A CN201610049737.1A CN201610049737A CN105664017A CN 105664017 A CN105664017 A CN 105664017A CN 201610049737 A CN201610049737 A CN 201610049737A CN 105664017 A CN105664017 A CN 105664017A
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刘德玉
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Abstract

本发明公开了一种球麻五窍喷雾剂系列的制备方法，涉及中医保健药品领域，该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮。该球麻五窍喷雾剂系列通过口腔黏膜快速雾化吸收的原理，达到病灶，从而治疗疾病为目的。每日3～4次，每次喷雾3～4次，安全可靠，无毒副作用。采用中医辩证施治中药治疗，取得了满意疗效，达到了既能改善症状及体征、又能控制疾病本身进展。该球麻五窍喷雾剂系列适用于真性球麻痹、假两性球麻痹，脑动脉硬化脱髓鞘。

Description

球麻五窍喷雾剂系列的制备方法
技术领域
本发明涉及中医保健药品领域，更具体地说，本发明涉及一种球麻五窍喷雾剂系列的制备方法。
背景技术
球麻痹也称延髓麻痹，是延髓的神经(舌咽神经、迷走神经、副神经、舌下神经)损害时，产生构音障碍、言语障碍、吞咽困难，严重者有后下回圈障碍。
目前的球麻痹，还没有一种科学而相对有效治疗方法，仍然是国内外治疗的难题、茫然无措；截至现在为止，也没有一种解除这种顽疾的临床治疗方法和药物。因此，真性球麻痹和假性球麻痹的治疗，是摆在我们每位临床医师面前的世界性前沿课题。
发明内容
本发明所要解决的问题是提供一种治疗球麻痹的球麻五窍喷雾剂系列的制备方法。
为了实现上述目的，本发明采取的技术方案为：一种球麻五窍喷雾剂系列的制备方法，其特征在于，该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮。
球麻五窍喷雾剂的原料及其重量比份为：石菖蒲60～120份、远志30～120份、冰片10～15份、乌梅40～80份、益智仁50～150份、6％醋酸溶液、龟板30～90份、半夏30～120份、95％酒精溶液、天麻30～90份、白芥子40～80份、木糖醇适量12份、皂荚15～75份、细辛10～30份、季节增效剂2份，球麻五窍喷雾剂的制备步骤为：(1)将上述各味名贵草药粉碎后置入容器内，酒浸及醋浸，密封3至5日；
(2)採用纳米技术提取灌入喷雾剂，雾化使用，低温保存备用。
益精填髓饮的原料及其重量比份为：熟地黄48份、益智仁50份、鹿角胶30份、枸杞子40份、石菖蒲45份、补骨脂40份、山萸肉30份、淮牛膝30份、五味子24份、淮山药30份、胡桃肉30份、当归30份、制首乌40份、黑脂麻30份、菊花30份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
荣路饮的原料及其重量比份为：生地黄90份、炮附子33份、远志45份、巴戟肉30份、石菖蒲40份、五味子37份、石斛30份、麦门冬55份、肉桂24份、山萸肉45份、当归40份、生黄芪99份、肉蓯蓉60份、淮山药45份、党参55份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
豁痰通腑汤的原料及其重量比份为：栝楼60份、葶藶子45份、车前子75份、胆南星30份、大黄33份、芒硝40份、五味子24份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，芒硝冲服，大黄后下，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
涤痰饮的原料及其重量比份为：栝楼40份、丹参90份、旋复花30份、胆南星25份、黄芩40份、百果30份、杏仁26份、石菖蒲40份、玉竹60份、天竺黄30份、郁金47份、川芎30份、枳实29份、柯子48份、桔梗片44份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
有益效果：本发明的球麻五窍喷雾剂系列通过口腔黏膜快速雾化吸收的原理，达到病灶，从而治疗疾病为目的。每日3～4次，每次喷雾3～4次，安全可靠，无毒副作用。采用中医辩证施治中药治疗，取得了满意疗效，达到了既能改善症状及体征、又能控制疾病本身进展。该球麻五窍喷雾剂系列适用于真性球麻痹、假两性球麻痹，脑动脉硬化脱髓鞘。
具体实施方式
实施例1：
该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮。
球麻五窍喷雾剂的原料及其重量比份为：石菖蒲60～120份、远志30～120份、冰片10～15份、乌梅40～80份、益智仁50～150份、6％醋酸溶液、龟板30～90份、半夏30～120份、95％酒精溶液、天麻30～90份、白芥子40～80份、木糖醇适量12份、皂荚15～75份、细辛10～30份、季节增效剂2份，球麻五窍喷雾剂的制备步骤为：(1)将上述各味名贵草药粉碎后置入容器内，酒浸及醋浸，密封3日；
(2)採用纳米技术提取灌入喷雾剂，雾化使用，低温保存备用。
益精填髓饮的原料及其重量比份为：熟地黄48份、益智仁50份、鹿角胶30份、枸杞子40份、石菖蒲45份、补骨脂40份、山萸肉30份、淮牛膝30份、五味子24份、淮山药30份、胡桃肉30份、当归30份、制首乌40份、黑脂麻30份、菊花30份，加凉水摸过水面浸泡2小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400ml，自动分装封袋100ml，低温储存备用。
荣路饮的原料及其重量比份为：生地黄90份、炮附子33份、远志45份、巴戟肉30份、石菖蒲40份、五味子37份、石斛30份、麦门冬55份、肉桂24份、山萸肉45份、当归40份、生黄芪99份、肉蓯蓉60份、淮山药45份、党参55份，加凉水摸过水面浸泡2小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400ml，自动分装封袋100ml，低温储存备用。
豁痰通腑汤的原料及其重量比份为：栝楼60份、葶藶子45份、车前子75份、胆南星30份、大黄33份、芒硝40份、五味子24份，加凉水摸过水面浸泡2小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30分钟，芒硝冲服，大黄后下，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400ml，自动分装封袋100ml，低温储存备用。
涤痰饮的原料及其重量比份为：栝楼40份、丹参90份、旋复花30份、胆南星25份、黄芩40份、百果30份、杏仁26份、石菖蒲40份、玉竹60份、天竺黄30份、郁金47份、川芎30份、枳实29份、柯子48份、桔梗片44份，加凉水摸过水面浸泡2小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400ml，自动分装封袋100ml，低温储存备用。
实施例2：
该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮。
球麻五窍喷雾剂的原料及其重量比份为：石菖蒲60～120份、远志30～120份、冰片10～15份、乌梅40～80份、益智仁50～150份、6％醋酸溶液、龟板30～90份、半夏30～120份、95％酒精溶液、天麻30～90份、白芥子40～80份、木糖醇适量12份、皂荚15～75份、细辛10～30份、季节增效剂2份，球麻五窍喷雾剂的制备步骤为：(1)将上述各味名贵草药粉碎后置入容器内，酒浸及醋浸，密封4日；
(2)採用纳米技术提取灌入喷雾剂，雾化使用，低温保存备用。
益精填髓饮的原料及其重量比份为：熟地黄48份、益智仁50份、鹿角胶30份、枸杞子40份、石菖蒲45份、补骨脂40份、山萸肉30份、淮牛膝30份、五味子24份、淮山药30份、胡桃肉30份、当归30份、制首乌40份、黑脂麻30份、菊花30份，加凉水摸过水面浸泡3小时，用砂锅或泥坛罐，焰火煮开后、改小火煮35分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至420ml，自动分装封袋120ml，低温储存备用。
荣路饮的原料及其重量比份为：生地黄90份、炮附子33份、远志45份、巴戟肉30份、石菖蒲40份、五味子37份、石斛30份、麦门冬55份、肉桂24份、山萸肉45份、当归40份、生黄芪99份、肉蓯蓉60份、淮山药45份、党参55份，加凉水摸过水面浸泡3小时，用砂锅或泥坛罐，焰火煮开后、改小火煮35分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至420ml，自动分装封袋120ml，低温储存备用。
豁痰通腑汤的原料及其重量比份为：栝楼60份、葶藶子45份、车前子75份、胆南星30份、大黄33份、芒硝40份、五味子24份，加凉水摸过水面浸泡3小时，用砂锅或泥坛罐，焰火煮开后、改小火煮35分钟，芒硝冲服，大黄后下，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至420ml，自动分装封袋120ml，低温储存备用。
涤痰饮的原料及其重量比份为：栝楼40份、丹参90份、旋复花30份、胆南星25份、黄芩40份、百果30份、杏仁26份、石菖蒲40份、玉竹60份、天竺黄30份、郁金47份、川芎30份、枳实29份、柯子48份、桔梗片44份，加凉水摸过水面浸泡3小时，用砂锅或泥坛罐，焰火煮开后、改小火煮35分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至420ml，自动分装封袋120ml，低温储存备用。
实施例3：
该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮。
球麻五窍喷雾剂的原料及其重量比份为：石菖蒲60～120份、远志30～120份、冰片10～15份、乌梅40～80份、益智仁50～150份、6％醋酸溶液、龟板30～90份、半夏30～120份、95％酒精溶液、天麻30～90份、白芥子40～80份、木糖醇适量12份、皂荚15～75份、细辛10～30份、季节增效剂2份，球麻五窍喷雾剂的制备步骤为：(1)将上述各味名贵草药粉碎后置入容器内，酒浸及醋浸，密封5日；
(2)採用纳米技术提取灌入喷雾剂，雾化使用，低温保存备用。
益精填髓饮的原料及其重量比份为：熟地黄48份、益智仁50份、鹿角胶30份、枸杞子40份、石菖蒲45份、补骨脂40份、山萸肉30份、淮牛膝30份、五味子24份、淮山药30份、胡桃肉30份、当归30份、制首乌40份、黑脂麻30份、菊花30份，加凉水摸过水面浸泡4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至450ml，自动分装封袋150ml，低温储存备用。
荣路饮的原料及其重量比份为：生地黄90份、炮附子33份、远志45份、巴戟肉30份、石菖蒲40份、五味子37份、石斛30份、麦门冬55份、肉桂24份、山萸肉45份、当归40份、生黄芪99份、肉蓯蓉60份、淮山药45份、党参55份，加凉水摸过水面浸泡4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至450ml，自动分装封袋150ml，低温储存备用。
豁痰通腑汤的原料及其重量比份为：栝楼60份、葶藶子45份、车前子75份、胆南星30份、大黄33份、芒硝40份、五味子24份，加凉水摸过水面浸泡4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮40分钟，芒硝冲服，大黄后下，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至450ml，自动分装封袋150ml，低温储存备用。
涤痰饮的原料及其重量比份为：栝楼40份、丹参90份、旋复花30份、胆南星25份、黄芩40份、百果30份、杏仁26份、石菖蒲40份、玉竹60份、天竺黄30份、郁金47份、川芎30份、枳实29份、柯子48份、桔梗片44份，加凉水摸过水面浸泡4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至450ml，自动分装封袋150ml，低温储存备用。
以上所述仅为本发明的实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书及实施方式内容所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。

Claims (5)

1.一种球麻五窍喷雾剂系列的制备方法，其特征在于，该球麻五窍喷雾剂系列包括球麻五窍喷雾剂、益精填髓饮、荣路饮、豁痰通腑汤、涤痰饮，其中球麻五窍喷雾剂的原料及其重量比份为：石菖蒲60～120份、远志30～120份、冰片10～15份、乌梅40～80份、益智仁50～150份、6％醋酸溶液、龟板30～90份、半夏30～120份、95％酒精溶液、天麻30～90份、白芥子40～80份、木糖醇适量12份、皂荚15～75份、细辛10～30份、季节增效剂2份，球麻五窍喷雾剂的制备步骤为：
(1)将上述各味名贵草药粉碎后置入容器内，酒浸及醋浸，密封3至5日；
(2)採用纳米技术提取灌入喷雾剂，雾化使用，低温保存备用。
2.按照权利要求1所述的球麻五窍喷雾剂系列的制备方法，其特征在于：所述益精填髓饮的原料及其重量比份为：熟地黄48份、益智仁50份、鹿角胶30份、枸杞子40份、石菖蒲45份、补骨脂40份、山萸肉30份、淮牛膝30份、五味子24份、淮山药30份、胡桃肉30份、当归30份、制首乌40份、黑脂麻30份、菊花30份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
3.按照权利要求1所述的球麻五窍喷雾剂系列的制备方法，其特征在于：所述荣路饮的原料及其重量比份为：生地黄90份、炮附子33份、远志45份、巴戟肉30份、石菖蒲40份、五味子37份、石斛30份、麦门冬55份、肉桂24份、山萸肉45份、当归40份、生黄芪99份、肉蓰蓉60份、淮山药45份、党参55份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
4.按照权利要求1所述的球麻五窍喷雾剂系列的制备方法，其特征在于：所述豁痰通腑汤的原料及其重量比份为：栝楼60份、葶藶子45份、车前子75份、胆南星30份、大黄33份、芒硝40份、五味子24份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，芒硝冲服，大黄后下，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
5.按照权利要求1所述的球麻五窍喷雾剂系列的制备方法，其特征在于：所述涤痰饮的原料及其重量比份为：栝楼40份、丹参90份、旋复花30份、胆南星25份、黄芩40份、百果30份、杏仁26份、石菖蒲40份、玉竹60份、天竺黄30份、郁金47份、川芎30份、枳实29份、柯子48份、桔梗片44份，加凉水摸过水面浸泡2～4小时，用砂锅或泥坛罐，焰火煮开后、改小火煮30～40分钟，虑过去渣后置入容器内、再加水煮开20分钟，两次水煎后混合浓缩至400～450ml，自动分装封袋100～150ml，低温储存备用。
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