CN105663446A - Drug for treating kidney cancer and preparation method - Google Patents

Drug for treating kidney cancer and preparation method Download PDF

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CN105663446A
CN105663446A CN201610108684.6A CN201610108684A CN105663446A CN 105663446 A CN105663446 A CN 105663446A CN 201610108684 A CN201610108684 A CN 201610108684A CN 105663446 A CN105663446 A CN 105663446A
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herba
drug
renal carcinoma
medicine
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李仁珍
赵海梅
王永雪
李洪颜
邱华
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Abstract

The invention discloses a drug for treating kidney cancer and a preparation method and belongs to the field of traditional Chinese medicine. Effective components of the drug disclosed by the invention are the following raw materials: radix sanguisorbae, fructus akebiae, herba cardui crispi, herba scutellariae barbatae, radix salviae miltiorrhizae, herba salviae chinensis, marsdenia tenacissima, mussel, four-leaf clover, herba peperomiae dindygulensis, poria cocos, adinandra mellettii, herba galii teneri, kelp, limonium wrightii and panax japonicus. According to the drug disclosed by the invention, all the selected traditional Chinese drugs are properly matched and complement each other; the drug has the effects of cooling blood and stopping bleeding, clearing away heat and detoxifying, inducing diuresis to alleviate edema, softening hardness to dissipate stagnation, tonifying liver and kidney, benefiting life essence and blood, eliminating goiters and tumors, resisting cancers and the like; all the drugs are combined and the drug function directly reaches a diseased region; the drug has the advantages of rapid effect, high curing rate, and no toxic and side effects on symptoms including hematuresis, lumps, lumbago, weight reduction, fever, abnormal liver functions, anemia, hypertension and the like caused by renal carcinoma, and is safe and convenient, is low in price and easy to prepare, and is worthy of being widely popularized and applied clinically.

Description

A kind of medicine treating renal carcinoma and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine treating renal carcinoma and preparation method.
Background technology
Renal carcinoma is initiated by the malignant tumor of excess of the kidney matter uriniferous tubule epithelial systems, and academic noun full name is renal cell carcinoma, also known as renal adenocarcinoma, referred to as renal carcinoma. Including the various renal cell carcinoma hypotypes originating from uriniferous tubule different parts, but do not include the tumor and the tumor of renal pelvis that derive from renal interstitial.
In the last few years, the asymptomatic renal carcinoma found when most of patients with renal cell carcinoma are due to Physical Examination, these patients accounted for more than the 50%-60% of patients with renal cell carcinoma sum. In Symptomatic patients with renal cell carcinoma, modal symptom is lumbago and hematuria, and small number of patients is to come institute with abdominal mass to go to a doctor. There is secondary tumor syndrome in the patient of 10%-40%, and show as hypertension, anemia, lose weight, cachexia, heating, erythrocytosis, abnormal liver function, hypercalcemia, hyperglycemia, erythrocyte sedimentation rate speed, neuromuscular pathological changes, amyloidosis, galactorrhea disease, clotting mechanism are abnormal etc. changes. The patient of 20%-30% can the symptom such as osteodynia caused by neoplasm metastasis, fracture, cough, spitting of blood go to a doctor.
A lot of people can cause suffering from renal carcinoma because not noting daily health care, and the appearance of renal carcinoma is very fearful, and the injury of human body is very big, and patient to be also subject to certain torment in spirit. If we treat not in time, the consequence caused also is very serious.
At present, operative treatment is the essential therapeutic arsenals of renal carcinoma, specifically include that underwent transurethral resection of bladder tumor (TURBT), Bladder stone Excision of bladder tumour (HOLRBT), partial cystectomy and radical cystectomy etc., but postoperative easy recurrence, patient suffering is big. For this, we are badly in need of developing a kind of medicine to help patient to break away from the misery that renal carcinoma is brought.
Summary of the invention
The invention provides a kind of medicine treating renal carcinoma and preparation method; Selected by medicine of the present invention, medical material compatibility is suitable, bring out the best in each other, and there is cooling blood for hemostasis, heat-clearing and toxic substances removing, inducing diuresis to remove edema, hard masses softening and resolving, invigorating the liver and kidney, benefiting essence-blood, the goiter that disappears, the effect such as anticancer, all medicines are harmonious the through diseased region of drug effect, hematuria that renal carcinoma is caused, lump, lumbago, lose weight, generate heat, symptom has instant effect, cure rate is high for abnormal liver function, anemia, hypertension etc., have no side effect, the advantage of safe ready, and low price, easily preparation, wide popularization and application on clinic.
For achieving the above object, technical scheme is implemented as follows:
A kind of medicine treating renal carcinoma, make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of medicine treating renal carcinoma, comprises the following steps that:
(1) Radix Sanguisorbae, Herba Salviae Chinensis and Herba Galii Teneri are twisted juice, filter impurity, stay juice, standby;
(2) Fructus Akebiae, Herba Cardui Crispi, Herba Peperomiae Dindygulensis and ring are participated in 10 times amount volumetric concentration 70% alcoholic solution extract three times, each 3 hours, filter, merging filtrate, place overnight, reclaim ethanol and to be concentrated into the dope that 60 DEG C of relative densities are 1.12-1.151 standby;
(3) Herba Scutellariae Barbatae, Radix Salviae Miltiorrhizae, Mytilus, Herba Galii Bungei, Poria, Adinandra millettii, Thallus Laminariae (Thallus Eckloniae) and Limonium wrightii Kuntz are put in container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion first 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract standby; It is 90% alcoholic solution that dry extract adds volumetric concentration, stands, is extracted by supernatant, and the extractum precipitated is standby;
(4) by Caulis Marsdeniae Tenacissimae microwave drying, grind into powder, obtained the fine powder of 180 orders, standby;
(5) juice, dope, extractum and the fine powder mixing that step (1)-step (4) prepares, makes tablet, is the medicine of described treatment renal carcinoma.
The property of medicine of Chinese medicine used by the present invention is as follows:
Radix Sanguisorbae: bitter in the mouth, acid, cold in nature; Return liver, lung, kidney, large intestine channel. Cooling blood for hemostasis, heat-clearing and toxic substances removing, sore of subsiding a swelling. Main haematemesis, spitting of blood, epistaxis, hematuria, have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting. " not Lu " load: " only pus and blood, all flaccidity, malignant boil, disappear wine, except quenching one's thirst, mends wound absolutely, and in puerperal, plug, can make incised wound cream. Main internal hemorrhage due to trauma is more than, insufficiency of blood. "
Fructus Akebiae: mildly bitter flavor, property is put down; Return liver, stomach, bladder warp. Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis. Main stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor. " Traditional Chinese Medicine in Sichuan will " carries: " soothing the liver, receive kidney qi. Control bladder hernia, spit blood. "
Herba Cardui Crispi: mildly bitter flavor, cool in nature. Expelling wind and clearing away heat, dampness removing, cooling blood for hemostasis, promoting blood circulation and detumescence. Main cold cough, dizziness of having a headache, urinary system infection, chyluria, leucorrhea, jaundice, rheumatic arthralgia, spit blood, epistaxis, hematuria, menorrhagia, dysfunctional uterine hemorrhage, traumatic injury, furuncle furuncle and phyma, swelling and pain of hemorrhoid, burn. Soviet Union doctor " Chinese herbal medicine handbook " load: " dispel the wind, dampness removing, heat clearing away, detumescence. Control chyluria, hematuria, urinary tract infection, influenza, leukorrhagia, menorrhagia; External curing pyogenic infections from tumour or sore, swelling and pain of hemorrhoid. "
Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature; Return lung, liver, kidney channel. Heat-clearing and toxic substances removing, dissipating blood stasis stops blooding, inducing diuresis to remove edema. Main pyretic toxicity carbuncle, has sore throat, lung abscess, acute appendicitis, scrofula, venom, traumatic injury, spits blood, epistaxis, stranguria with blood, edema, ascites and cancer.Guangzhou army " conventional Chinese herbal medicine handbook " load: " heat-clearing and toxic substances removing. For cancer see the effect improving symptom; Appendicitis, hepatitis. "
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature; GUIXIN, pericardium, Liver Channel. Blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, nourishing blood to tranquillize the mind, removing heat from blood eliminating carbuncle. Main menoxenia, dysmenorrhea, amenorrhea, puerperal the stagnant stomachache of the stasis of blood, trusted subordinate's pain, lump in the abdomen, pyretic arthralgia swells and ache, traumatic injury, and heat enters nutrient blood, dysphoria, vexed insomnia, ulcerative carbuncle toxic swelling. " Japan hanako materia medica " carries: " sedate of reposing, tonneau GUAN-pulse. Controlling cold and hot labor, arthralgia, extremity are unsuccessful; Evacuation of pus pain relieving, granulation promoting is put on flesh; Broken stagnated blood, mends new hemopoietic; Peaceful tire, fall stillborn fetus; Under hemostasis metrorrhagia and leukorrhagia, adjusting married woman's passages through which vital energy circulates irregular, blood evil thought is tired of; Malignant boil scabies, wart is gone to live in the household of one's in-laws on getting married toxic swelling, erysipelas; Headache, acute conjunctivitis, heat temperature is mad vexed. "
Herba Salviae Chinensis: acrid in the mouth, hardship, cold nature; Return liver, spleen channel. Blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating. Main menoxenia, dysmenorrhea, amenorrhea, metrorrhagia, have blood in stool, jaundice due to damp-heat, hot toxic-heat and blood stasis, drench pain, leukorrhagia, rheumatic ostalgia, scrofula, skin ulcer swells, acute mastitis, herpes zoster, leprosy, and traumatic injury wound is swollen. " detailed outline " carries: " main osteodynia, strong wind, carbuncle. "
Caulis Marsdeniae Tenacissimae: bitter in the mouth, cold nature; Return lung, Liver Channel. Heat-clearing and toxic substances removing, relieving cough and asthma, tonneau wets lactogenesis, does cancer. Main laryngopharynx swelling and pain, lung-heat cough with asthma, jaundice due to damp-heat, dysuria, galactostasis, furuncle, cancerous protuberance. " choosing of Yunnan Chinese herbal medicine " carries: " antiinflammatory, cough-relieving are relievingd asthma, anticancer. Control bronchitis, bronchial asthma, various cancers, rheumatism, traumatic injury, fracture, optical fundus illness, gastropathy. "
Mytilus: sweet in the mouth, salty, warm in nature; Return liver, kidney channel. Invigorating the liver and kidney, benefiting essence-blood, disappear goiter. Main asthenia weakness and emaciation, dizziness, night sweat, sexual impotence, lumbago, spit blood, metrorrhagia, leukorrhagia, goiter. " occupying diet spectrum with breath " load: " the kidney invigorating, benefit blood replenishing essence are controlled something lost, are with, collapse, are drenched, and sexual impotence is sombre, quenches one's thirst, goiter. "
Herba Galii Bungei: sweet in the mouth, hardship, property is put down; Return liver, spleen channel. Clearing away heat and promoting diuresis, removing toxic substances and promoting subsidence of swelling. Main urinary tract infection, cancerous protuberance, leucorrhea with red and white discharge, dysentery, carbuncle, traumatic injury, hemoptysis, women's leucorrhea with red and white discharge, infantile malnutrition, carbuncle furunculosis, venom. Soviet Union doctor " Chinese herbal medicine handbook " load: " inducing diuresis to remove edema, anticancer. Control urinary tract infection, leucorrhea with red and white discharge, cervical erosion, suppurative inflammation. And control cerebrospinal meningitis, septic septicemia, carbuncle, venom, skin sore edema, cancerous protuberance. "
Herba Peperomiae Dindygulensis: acrid in the mouth, cool in nature; Return lung, spleen, liver, kidney channel. Heat-clearing and toxic substances removing, blood stasis-eliminating and stagnation-dissipating, inducing diuresis to remove edema. Main lung-heat cough with asthma, measles, sore, cancerous protuberance, burn and scald, traumatic injury, oedema due to nephritis. " choosing of Yunnan Chinese herbal medicine " load load: " eliminating stasis and resolving masses, anticancer. Control gastric cancer, esophageal carcinoma, hepatocarcinoma, breast carcinoma, pulmonary carcinoma. "
Poria: sweet in the mouth, light, property is put down; GUIXIN, spleen, lung, kidney channel. Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming. Main dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, nebulousurine of passing out semen. " not Lu " load: " only quench one's thirst, like to sleep, big abdomen, drench drop, the disease due to obstruction of QI of middle-JIAO expectorant water, edema drenches knot. Opening breast internal organs, adjust visceral-qi, cut down kidney heresy, long the moon, physical strength profiting, during guarantor god keeps. " modern medicine study confirmation, this product has antitumor action.
Adinandra millettii: bitter in the mouth, cool in nature;Return lung, Liver Channel. Cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling. Main epistaxis, hematuria, infectious hepatitis, parotitis, furuncle and phyma, snake bite and insect sting, cancerous protuberance.
Herba Galii Teneri: acrid in the mouth, micro-hardship, cold nature; Return Shao Yin, Taiyin channels. Heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, reducing swelling and alleviating pain. Main swollen ulcer drug, mastitis, appendicitis, edema, cold, fever, dysentery, urinary tract infection, hematuria, gingival hemorrhage, knife injury is hemorrhage. Jiangxi " medical herbs handbook " is carried: " heat-clearing and toxic substances removing, reducing swelling and alleviating pain. Controlling carbuncle, appendicitis, closely for for cancer. " clinical trial proves, this product has the effect for the treatment of tumor.
Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature; Return liver, stomach, kidney, spleen channel. Eliminating phlegm and softening indurated mass, diuretic detumescent. Main scrofula, goiter, dysphagic, (Epileptic is ruined) hernia beriberi edema. " beautiful Chinese catalpa medicine solution " load: " sluicing is dried, removing mass softening the hard mass. Clearing away heat and promoting diuresis, controls flatulence watery distension, scrofula goiter, and TUI hernia malignant boil, with Sargassum, the same merit of Thallus Laminariae (Thallus Eckloniae). "
Limonium wrightii Kuntz: lightly seasoned, cool in nature; Inducing diuresis to remove edema. Main edema.
Rhizoma Panacis Japonici: sweet in the mouth, micro-hardship, slightly warm in nature; Return lung, spleen, Liver Channel. Xu-tonic, eliminating phlegm and stopping cough, dissipating blood stasis stops blooding, reducing swelling and alleviating pain. Main weak after being ill, inappetence, cough due to consumptive disease, spitting of blood, spit blood, epistaxis, to have blood in stool, hematuria, vicarious menstruation, metrorrhagia, traumatic hemorrhage, lump in the abdomen, blood stasis amenorrhea, puerperal, stasis of blood the moon was suffered from abdominal pain, traumatic injury, rheumatic arthritis, carbuncle, hemorrhoid, venom.
The present invention compared with prior art, has the advantages that
Selected by medicine of the present invention, medical material compatibility is suitable, bring out the best in each other, and there is cooling blood for hemostasis, heat-clearing and toxic substances removing, inducing diuresis to remove edema, hard masses softening and resolving, invigorating the liver and kidney, benefiting essence-blood, the goiter that disappears, the effect such as anticancer, all medicines are harmonious the through diseased region of drug effect, hematuria that renal carcinoma is caused, lump, lumbago, lose weight, generate heat, symptom has instant effect, cure rate is high for abnormal liver function, anemia, hypertension etc., have no side effect, the advantage of safe ready, and low price, easily preparation, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
The processing step of process for preparing medicine of the present invention is:
(1) Radix Sanguisorbae, Herba Salviae Chinensis and Herba Galii Teneri are twisted juice, filter impurity, stay juice, standby;
(2) Fructus Akebiae, Herba Cardui Crispi, Herba Peperomiae Dindygulensis and ring are participated in 10 times amount volumetric concentration 70% alcoholic solution extract three times, each 3 hours, filter, merging filtrate, place overnight, reclaim ethanol and to be concentrated into the dope that 60 DEG C of relative densities are 1.12-1.151 standby;
(3) Herba Scutellariae Barbatae, Radix Salviae Miltiorrhizae, Mytilus, Herba Galii Bungei, Poria, Adinandra millettii, Thallus Laminariae (Thallus Eckloniae) and Limonium wrightii Kuntz are put in container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion first 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract standby; It is 90% alcoholic solution that dry extract adds volumetric concentration, stands, is extracted by supernatant, and the extractum precipitated is standby;
(4) by Caulis Marsdeniae Tenacissimae microwave drying, grind into powder, obtained the fine powder of 180 orders, standby;
(5) juice, dope, extractum and the fine powder mixing that step (1)-step (4) prepares, makes tablet, is the medicine of described treatment renal carcinoma.
Usage and dosage: oral, every day 3 times, each 3,15 days be a course for the treatment of, and 3 to 5 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage and embodiment 1 are identical.
Clinical data:
1, case selection:
As the medicine for the treatment of renal carcinoma, selecting the patients with renal cell carcinoma 336 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group 168 example, wherein male 84 example, women 84 example, age 27-70 year, 46.8 years old mean age, course of disease 1-8; Matched group 168 example, wherein male 84 example, women 84 example, age 25-70 year, 45.4 years old mean age, course of disease 1-5. The course of disease of two groups of cases, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, every day 3 times, each 3, and warm water delivery service in half an hour after meal 15 days is a course for the treatment of, takes 3 to 5 courses for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group uses Sorafenib, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: hematuria, lump, lumbago, lose weight, generate heat, the renal carcinoma transference cure such as abnormal liver function, anemia, hypertension, physical recovery is normal.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Taking in the treatment group of medicine of the present invention, cure 118 examples, effective 47 examples, invalid 3 examples, cure rate is 70.2%, total effective rate 98.2%.
Curing 50 examples, effective 48 examples, invalid 70 examples in matched group, cure rate is 29.8%, total effective rate 58.3%.
Result above shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Hu, man, 69 years old, retired worker, Sichuan Ziyang Man. There is hematuria, lump, lumbago shape without obvious inducement in patient, does not take a favorable turn in local hospital treatment. To our hospital for this, it is diagnosed as renal carcinoma on inspection. After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom is clearly better; Continuing to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom all disappears, recovery from illness, follows up a case by regular visits to, does not recur.
2, certain is thanked, man, 52 years old, it is engaged in agriculture, people from Jilin, northeast. Patient was diagnosed as renal carcinoma before 2 years, occurred that tired, xerostomia is intended to drink, discomfort uncomfortable in chest, chest pain catch cropping, coughs the symptoms such as vomiting pus expectorant, constipation with dry stool, frequent micturition, dysurea, hematuria. To our hospital, take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom is clearly better; Continuing to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, recovery from illness, follows up a case by regular visits to, does not recur.
3, certain is tried to gain, female, 44 years old, housewife, Linfen, Shanxi people. Patient suffers from renal carcinoma more than 2 years, the symptom such as hematuria, lump, lumbago occur, lose weight, and does not take an evident turn for the better after local hospital is treated. Introduce to our hospital by friend. After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom starts to take a turn for the better;After continuing to take 3 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, recovery from illness, follows up a case by regular visits to, does not recur.
4, Zhang, man, 38 years old, self-employed entrepreneurs, Baiyin people. Patient suffers from renal carcinoma more than 1 year, does not once take an evident turn for the better after multiple hospitals gives Drug therapy, introduces to our hospital by local doctor. Taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better; After continuing to take 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, recovery from illness, follows up a case by regular visits to, does not recur.
5, Zheng, man, 33 years old, supervisor, Liaoning people from Huludao City. Patient was diagnosed as renal carcinoma before 3 years, had carried out renal carcinoma ablation, after hematuria, dysurea symptom occur, check and find recurrence. For asking further diagnosis and treatment to our hospital. After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better; Continuing to take 3 courses for the treatment of of medicine of the present invention, above-mentioned symptom disappears, recovery from illness, follows up a case by regular visits to, does not recur.
6, high certain, female, 28 years old, make up artist, people from Cangzhou, Hebei. There is hematuria, dysurea, lumbago shape in patient. Then arrive local hospital to go to a doctor, be diagnosed as renal carcinoma, do not take an evident turn for the better after giving Drug therapy. For asking further diagnosis and treatment to our hospital. Taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better; Continuing to take medicine of the present invention, after 2 courses for the treatment of, above-mentioned symptom disappears, and recovery from illness is followed up a case by regular visits to, do not recurred.

Claims (5)

1. the medicine treating renal carcinoma, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
Radix Sanguisorbae 37-69 part Fructus Akebiae 33-65 part Herba Cardui Crispi 33-65 part Herba Scutellariae Barbatae 31-63 part
Radix Salviae Miltiorrhizae 29-61 part Herba Salviae Chinensis 29-61 part Caulis Marsdeniae Tenacissimae 27-51 part Mytilus 27-51 part
Herba Galii Bungei 25-49 part Herba Peperomiae Dindygulensis 25-49 part Poria 24-45 part Adinandra millettii 24-45 part
Herba Galii Teneri 23-43 part Thallus Laminariae (Thallus Eckloniae) 22-42 part Limonium wrightii Kuntz 20-40 part Rhizoma Panacis Japonici 18-30 part.
2. a kind of medicine treating renal carcinoma according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
62 parts of Fructus Akebiaes of Radix Sanguisorbae, 57 portions of Herba Scutellariae Barbataes of 57 parts of Herba Cardui Crispi 55 parts
53 parts of Herba Salviae Chinensiss of Radix Salviae Miltiorrhizae, 45 portions of Mytilus of 53 parts of Caulis Marsdeniae Tenacissimaes 45 parts
43 parts of Herba Peperomiae Dindygulensiss of Herba Galii Bungei, 40 parts of Adinandra millettii of 43 parts of Poria 40 parts
38 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Galii Teneri, 35 parts of Rhizoma Panacis Japonicis of 37 parts of Limonium wrightii Kuntz 27 parts.
3. a kind of medicine treating renal carcinoma according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
55 parts of Fructus Akebiaes of Radix Sanguisorbae, 49 portions of Herba Scutellariae Barbataes of 49 parts of Herba Cardui Crispi 47 parts
45 parts of Herba Salviae Chinensiss of Radix Salviae Miltiorrhizae, 39 portions of Mytilus of 45 parts of Caulis Marsdeniae Tenacissimaes 39 parts
37 parts of Herba Peperomiae Dindygulensiss of Herba Galii Bungei, 35 parts of Adinandra millettii of 37 parts of Poria 35 parts
33 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Galii Teneri, 30 parts of Rhizoma Panacis Japonicis of 32 parts of Limonium wrightii Kuntz 24 parts.
4. a kind of medicine treating renal carcinoma according to claim 1, it is characterised in that: make described effective ingredient raw material composition and parts by weight be:
47 parts of Fructus Akebiaes of Radix Sanguisorbae, 41 portions of Herba Scutellariae Barbataes of 41 parts of Herba Cardui Crispi 39 parts
37 parts of Herba Salviae Chinensiss of Radix Salviae Miltiorrhizae, 33 portions of Mytilus of 37 parts of Caulis Marsdeniae Tenacissimaes 33 parts
31 parts of Herba Peperomiae Dindygulensiss of Herba Galii Bungei, 30 parts of Adinandra millettii of 31 parts of Poria 30 parts
28 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Galii Teneri, 25 parts of Rhizoma Panacis Japonicis of 27 parts of Limonium wrightii Kuntz 21 parts.
5. the preparation method of the medicine of the treatment renal carcinoma as described in any one of claim 1-4, it is characterised in that: comprise the following steps that:
(1) Radix Sanguisorbae, Herba Salviae Chinensis and Herba Galii Teneri are twisted juice, filter impurity, stay juice, standby;
(2) Fructus Akebiae, Herba Cardui Crispi, Herba Peperomiae Dindygulensis and ring are participated in 10 times amount volumetric concentration 70% alcoholic solution extract three times, each 3 hours, filter, merging filtrate, place overnight, reclaim ethanol and to be concentrated into the dope that 60 DEG C of relative densities are 1.12-1.151 standby;
(3) Herba Scutellariae Barbatae, Radix Salviae Miltiorrhizae, Mytilus, Herba Galii Bungei, Poria, Adinandra millettii, Thallus Laminariae (Thallus Eckloniae) and Limonium wrightii Kuntz are put in container, add distilled water and boil extraction 3 times, add 10-15 times amount distilled water immersion first 4-5 hour, heated and boiled 3-4 hour, extract; Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extracts; Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts; Merge three extracting solution, filter, obtain filtrate, be condensed into dry extract standby; It is 90% alcoholic solution that dry extract adds volumetric concentration, stands, is extracted by supernatant, and the extractum precipitated is standby;
(4) by Caulis Marsdeniae Tenacissimae microwave drying, grind into powder, obtained the fine powder of 180 orders, standby;
(5) juice, dope, extractum and the fine powder mixing that step (1)-step (4) prepares, makes tablet, is the medicine of described treatment renal carcinoma.
CN201610108684.6A 2016-02-27 2016-02-27 Drug for treating kidney cancer and preparation method Pending CN105663446A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106074851A (en) * 2016-08-03 2016-11-09 解颖 A kind of Chinese medicine composition is used for the application treating in the medicine of renal carcinoma in preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189287A (en) * 2014-09-15 2014-12-10 秦银忠 Traditional Chinese medicine preparation for treating kidney cancer, and preparation method of traditional Chinese medicine preparation
CN104825909A (en) * 2015-06-04 2015-08-12 孙长发 TCM (traditional Chinese medicine) preparation for renal cancer and preparing method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104189287A (en) * 2014-09-15 2014-12-10 秦银忠 Traditional Chinese medicine preparation for treating kidney cancer, and preparation method of traditional Chinese medicine preparation
CN104825909A (en) * 2015-06-04 2015-08-12 孙长发 TCM (traditional Chinese medicine) preparation for renal cancer and preparing method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106074851A (en) * 2016-08-03 2016-11-09 解颖 A kind of Chinese medicine composition is used for the application treating in the medicine of renal carcinoma in preparation
CN106074851B (en) * 2016-08-03 2019-08-09 黑龙江中医药大学 A kind of Chinese medicine composition is preparing the application in the drug for treating kidney

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Application publication date: 20160615