CN105641663A - 一种用于治疗痞满的内服药物及其制备方法 - Google Patents

一种用于治疗痞满的内服药物及其制备方法 Download PDF

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CN105641663A
CN105641663A CN201610129348.XA CN201610129348A CN105641663A CN 105641663 A CN105641663 A CN 105641663A CN 201610129348 A CN201610129348 A CN 201610129348A CN 105641663 A CN105641663 A CN 105641663A
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任云翠
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Chengdu Fuhaosi Biotechnology Co Ltd
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Abstract

本发明属于中医药技术领域,目的是根据中医对痞满的认识机理而提供的一种用于治疗痞满的内服药物,所述药物的各个组分及其质量份比如下所示:生姜3~12g、甘草3~18g、泽泻6~10g、旋复花3~12g、厚朴3~10g、枳实(炒)7.5~15g、神曲10~17g、枳壳5~15g、瓜萎子15~20g、白术7.5~16g、延胡索7.5~16g、佛手柑15~26g、太子参10~16g、九香虫3~10g、吴茱萸3~9g、桂枝3~9g、郁李仁5~16g、香橼3~7g、细辛3~6g、透骨草9~16g、鸡内金6~16g、枇杷叶7.5~15g、砂仁5~10g、乌梅4~8g、陈皮3~11g、半枝莲15~30g、炒草果仁3~6g、山楂3~12g、丁香2~5g;本发明提供的药物是一个标本兼治的中药配方。

Description

一种用于治疗痞满的内服药物及其制备方法
技术领域
本发明涉及中医药技术领域,具体涉及一种用于治疗痞满的内服药物,特别是供痞满患者使用的内服药物及其制备方法的领域。
背景技术
痞满是由表邪内陷,饮食不节,痰湿阻滞,情志失调,脾胃虚弱等导致脾胃功能失调,升降失司,胃气壅塞而成的,以胸脘痞塞满闷不舒,按之柔软,压之不痛,视之无胀大之形为主要临床特征的一种脾胃病证。由于目前西药无法有效治疗痞满,因此人们对快速有效治疗痞满的中药药物存在极大的需求。
那么,就如何找到一种可有效治疗痞满的药物,是我们目前急需要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗痞满上,人们逐渐意识到了中医治疗上述疾病的优点,且在治疗过程中毒副作用小、费用低等优势,针对现有西医治疗痞满的现状,本发明的目的是在于提供一种用于治疗痞满的内服药物,以解决痞满患者早日恢复健康的问题。该药物是以常见的中药为原料,具有见效快、疗效显著等特点,并可有效治疗痞满一症。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种用于治疗痞满的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
生姜3~12g、甘草3~18g、泽泻6~10g、旋复花3~12g、厚朴3~10g、枳实(炒)7.5~15g、神曲10~17g、枳壳5~15g、瓜萎子15~20g、白术7.5~16g、延胡索7.5~16g、佛手柑15~26g、太子参10~16g、九香虫3~10g、吴茱萸3~9g、桂枝3~9g、郁李仁5~16g、香橼3~7g、细辛3~6g、透骨草9~16g、鸡内金6~16g、枇杷叶7.5~15g、砂仁5~10g、乌梅4~8g、陈皮3~11g、半枝莲15~30g、炒草果仁3~6g、山楂3~12g、丁香2~5g。
一种用于治疗痞满的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
生姜8~11g、甘草10~16g、泽泻7~9g、旋复花8~11g、厚朴6~9g、枳实(炒)10~13g、神曲11~15g、枳壳8~13g、瓜萎子15~17g、白术8~14g、延胡索8~14g、佛手柑18~23g、太子参11~14g、九香虫6~9g、吴茱萸6~8g、桂枝5~8g、郁李仁8~14g、香橼4~6g、细辛4~5.5g、透骨草10~14g、鸡内金8~14g、枇杷叶8~13g、砂仁6~9g、乌梅5~7g、陈皮6~10g、半枝莲20~26g、炒草果仁4~5.5g、山楂6~11g、丁香3~4.5g。
一种用于治疗痞满的内服药物及其制备方法,其特征在于,所述“最佳方案”的药物的各个组分及其质量份比如下所示
生姜10g、甘草14g、泽泻8g、旋复花10g、厚朴8g、枳实(炒)12g、神曲13g、枳壳12g、瓜萎子15g、白术13g、延胡索13g、佛手柑20g、太子参13g、九香虫8g、吴茱萸7g、桂枝7g、郁李仁13g、香橼5g、细辛5g、透骨草13g、鸡内金13g、枇杷叶12g、砂仁8g、乌梅6g、陈皮9g、半枝莲23g、炒草果仁5g、山楂10g、丁香4g。
一种用于治疗痞满的内服药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、首先将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、(1)将包好的原料中药放入冷开水中浸泡半小时,然后再将浸泡好的药物物和浸泡药物的澄清液一并放入煎药机煎煮两次,第一次加入过药36mm的冷开水,先武火煎煮10分钟后,再用文火煎煮28分钟,过滤即得第一次煎煮液;(2)将第一次过滤后的药渣再加入过药30mm的冷开水,先武火煎煮沸,再用文火煎煮25分钟,过滤得第二次煎煮液;(3)二次合并煎煮液,武火煮沸,再用文火煎煮8分钟,混合浓缩成50%的中药液2160毫升,袋装密封后,入冰箱保鲜备用。
一种用于治疗痞满的内服药物及其制备方法,其特征在于,所述服用方法为:将制备好的中药液分四天服用,早中晚各服一次,给药量180毫升/次,饭前服。服药7~21天,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
生姜,性味:辛、微温,具有解表散寒、温中止呕、温肺止咳、化痰止咳、解毒之功效,用于治疗外感风寒及胃寒呕逆等症;
甘草,性味:甘、平,具有补脾益气、清热解毒、祛痰止咳、缓急止痛、调和诸药之功效,用于治疗脾胃虚弱、倦怠乏力、心悸气短、咳嗽痰多、脘腹、四肢挛急疼痛、痈肿疮毒、缓解药物毒性、烈性等症;
泽泻,性味:甘、寒,具有利小便、清湿热之功效,用于治疗小便不利、水肿胀满、泄泻尿少、痰饮眩晕、热淋涩痛,高血脂;
旋复花,性味:味苦、辛、咸、微温,具有消痰行水、降气止呕之功效,用于治疗咳喘痰粘、哆嗦噫气、胸痞胁痛;
厚朴,性味:苦、辛、温,具有燥湿消痰、下气除满之功效,用于治疗湿阻中焦、脘腹胀满、食积气滞、腹胀便秘、痰饮喘咳,此外,七情郁结、痰气互阻、咽中如有物阻、咽之不下、吐之不出的梅核气证,亦可取本品燥湿消痰,下气宽中之效;
枳实(炒),性味:苦、寒,具有破气、散痞、泻痰、消积之功效,用于治疗胸腹胀满、胸痹、痞痛、痰癖、水肿、食积、便秘、胃下垂、子宫下垂、脱肛等症;
神曲,性味:苦、温,具有健脾消食、理气化湿、解表之功效,用于治疗伤食胸痞、腹痛吐泻、痢疾、感冒头痛、小儿伤饥失饱;
枳壳,性味:味苦、酸、性微寒,具有破气、行痰、消积之功效,用于治疗胸膈痰滞、胸痞、胁胀、食积、噫气、呕逆、下痢后重、脱肛、子宫脱垂;
瓜萎子,性味:甘、寒,具有润肺、化痰、滑肠之功效,用于治疗痰热咳嗽、燥结便秘、痈肿、乳少;
白术,性味:味苦、甘、性温,具有健脾益气、燥湿利水、止汗、安胎之功效,用于治疗脾气虚弱、神疲乏力、食少少腹胀、大便溏薄、水饮内停、小便不利、水肿、痰饮眩晕、温痹酸痛、气虚自汗、胎动不安等症;
延胡索,性味:辛、苦、温,具有活血、散瘀、理气、止痛之功效,用于治疗心腹腰膝诸痛、月经不调、症瘕、崩中、产后血晕、恶露不尽、跌打损伤,还用于胸胁、脘腹疼痛、经闭痛经、产后瘀阻、跌扑肿痛;
佛手柑,性味:味苦辛、性平,具有理气、化痰之功效,用于治疗胃痛、胁胀、呕吐、噎膈、痰饮咳喘、并能解酒;
太子参,性味:甘、微苦、性微寒,具有补益脾肺、益气生津之功效,用于治疗脾胃虚弱、食欲不振、倦怠无力、气阴两伤、干咳痰少、自汗气短、以及温病后期气虚津伤、内热口渴、或神经衰弱、心悸失眠、头昏健忘、小儿夏季热;
九香虫,性味:味咸、性温,具有行气止痛、温肾壮阳之功效,用于治疗肝胃不和或寒郁中焦所致的胸历胁胃脘胀痛,以及坚阳不足之腰痛、阳痿等症;
吴茱萸,性味:辛、苦、大热、有小毒,具有疏肝下气、温中散寒、燥湿助阳之功效,用于治疗劂阴头痛、胸腹胀满、呕吐吞酸、阳虚泄泻、吐泻转筋、寒疝脚气,外治口舌生疮;
桂枝,性味:辛、甘、温,具有发汗解肌、温通经脉、助阳化气、平冲降气之功效,用于治疗风寒感冒、脘腹冷痛、血寒经闭、关节痹痛、痰饮、水肿、心悸、奔豚;
郁李仁,性味:辛、苦甘、平,无毒,具有润燥滑肠、下气利水之功效,用于治疗大肠气滞、燥涩不通、小便不利、大腹水肿、四肢浮肿、脚气等症;
香橼,性味:辛、苦、酸、温,具有理气降逆、宽胸化痰之功效,用于治疗胸腹满闷、胁肋胀痛、咳嗽痰多;
细辛,性味:辛、温,具有祛风、散寒、行水、开窍之功效,用于治疗风冷头痛、鼻渊、齿痛、痰饮咳逆、风湿痹痛;
透骨草,性味:辛;性温,具有祛风除湿、舒筋活血、散瘀消肿、解毒目痛之功效,用于治疗风湿痹痛、筋骨挛缩、寒湿脚气、腰部扭伤、瘫痪、闭经、阴囊湿疹、疮疖肿毒;
鸡内金,性味:甘、平,具有消积滞、健脾胃之功效,用于治疗食积胀满、呕吐反胃、泻痢、疳积、消渴、遗溺、喉痹乳蛾、牙疳口疮等病症;
枇杷叶,性味:苦,凉,具有清肺和胃,降气化痰之功效,用于治疗肺热痰嗽、咳血、衄血、胃热呕哕;
砂仁,性味:味辛、性温,具有化湿开胃、行气宽中温脾止泻安胎之功效,用于治疗湿阻气滞、脘腹胀满、不思饮食、恶心呕吐、腹痛泄泻妊娠恶阻、胎动不安等症;
乌梅,性味:味酸、性平,具有敛肺止咳、涩肠止泻、止血、生津、安蛔之功效,用于治疗久咳、虚热烦渴、久疟、久泻、痢疾、便血、尿血、血崩、蛔厥腹痛、呕吐、钩虫病;
陈皮,性味:苦、辛、温,具有理气健脾、调中、燥湿、化痰之功效,用于治疗脾胃气滞之脘腹胀满或疼痛、消化不良、湿浊阻中之胸闷腹胀、纳呆便溏、痰湿壅肺之咳嗽气喘、食少吐泻、咳嗽痰多等症;
半枝莲,性味:味辛、苦、性寒,具有清热解毒、散瘀止血、利尿消肿之功效,用于治疗热毒痈肿、咽喉疼痛、肺痈、肠痈、瘰疬、毒蛇咬伤、跌打损伤、吐血、衄血、血淋、水肿、腹水及癌症;
炒草果仁,性味:味辛、性温,具有燥湿温中、除痰截疟之功效,用于治疗寒湿内阻、脘腹胀满、痞满呕吐、疟疾寒热;
山楂,性味:酸甘、微温,具有消食积、化滞瘀之功效,用于治疗饮食积滞、脘腹胀痛、泄泻痢疾、血瘀痛经、闭经、产后腹痛、恶露不尽;
丁香,性味:味辛、性温,具有温中降逆、温肾助阳之功效,用于治疗呃逆、脘腹冷痛、食少叶泻、肾虚阳痿、腰膝酸冷、阴疽。
本发明药物是基于中医治疗痞满的辨病与辨证相结合的原则,从药理作用及作用机制认为:就痞满一症,本发明所提供的中药组合物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述痞满的治疗而提出的一种中药配方,采用该配方制备的中药组合物,药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种用于治疗痞满的内服药物,所述药物的各个组分及其质量份比如下所示:
生姜10g、甘草14g、泽泻8g、旋复花10g、厚朴8g、枳实(炒)12g、神曲13g、枳壳12g、瓜萎子15g、白术13g、延胡索13g、佛手柑20g、太子参13g、九香虫8g、吴茱萸7g、桂枝7g、郁李仁13g、香橼5g、细辛5g、透骨草13g、鸡内金13g、枇杷叶12g、砂仁8g、乌梅6g、陈皮9g、半枝莲23g、炒草果仁5g、山楂10g、丁香4g。
实施例2:
一种用于治疗痞满的内服药物,所述药物的各个组分及其质量份比如下所示:
生姜11g、甘草16g、泽泻9g、旋复花11g、厚朴9g、枳实(炒)13g、神曲15g、枳壳13g、瓜萎子17g、白术14g、延胡索14g、佛手柑23g、太子参14g、九香虫9g、吴茱萸8g、桂枝8g、郁李仁14g、香橼6g、细辛5.5g、透骨草14g、鸡内金14g、枇杷叶13g、砂仁9g、乌梅7g、陈皮10g、半枝莲26g、炒草果仁5.5g、山楂11g、丁香4.5g。
实施例3:
一种用于治疗痞满的内服药物,所述药物的各个组分及其质量份比如下所示:
生姜12g、甘草18g、泽泻10g、旋复花12g、厚朴10g、枳实(炒)15g、神曲17g、枳壳15g、瓜萎子20g、白术16g、延胡索16g、佛手柑26g、太子参16g、九香虫10g、吴茱萸9g、桂枝9g、郁李仁16g、香橼7g、细辛6g、透骨草16g、鸡内金16g、枇杷叶15g、砂仁10g、乌梅8g、陈皮11g、半枝莲30g、炒草果仁6g、山楂12g、丁香5g。
典型病例:
经临床诊断治疗痞满患者共100例,年龄为39以上的63例,只有37例为39岁以下。100例患者痊愈的87例,显效的13例,总有效率达100%。经治疗后,病获痊愈。

Claims (3)

1.一种用于治疗痞满的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
生姜3~12g、甘草3~18g、泽泻6~10g、旋复花3~12g、厚朴3~10g、枳实(炒)7.5~15g、神曲10~17g、枳壳5~15g、瓜萎子15~20g、白术7.5~16g、延胡索7.5~16g、佛手柑15~26g、太子参10~16g、九香虫3~10g、吴茱萸3~9g、桂枝3~9g、郁李仁5~16g、香橼3~7g、细辛3~6g、透骨草9~16g、鸡内金6~16g、枇杷叶7.5~15g、砂仁5~10g、乌梅4~8g、陈皮3~11g、半枝莲15~30g、炒草果仁3~6g、山楂3~12g、丁香2~5g。
2.根据权利要求1所述的治疗痞满的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
生姜8~11g、甘草10~16g、泽泻7~9g、旋复花8~11g、厚朴6~9g、枳实(炒)10~13g、神曲11~15g、枳壳8~13g、瓜萎子15~17g、白术8~14g、延胡索8~14g、佛手柑18~23g、太子参11~14g、九香虫6~9g、吴茱萸6~8g、桂枝5~8g、郁李仁8~14g、香橼4~6g、细辛4~5.5g、透骨草10~14g、鸡内金8~14g、枇杷叶8~13g、砂仁6~9g、乌梅5~7g、陈皮6~10g、半枝莲20~26g、炒草果仁4~5.5g、山楂6~11g、丁香3~4.5g。
3.根据权利要求1至2所述的治疗痞满的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
生姜10g、甘草14g、泽泻8g、旋复花10g、厚朴8g、枳实(炒)12g、神曲13g、枳壳12g、瓜萎子15g、白术13g、延胡索13g、佛手柑20g、太子参13g、九香虫8g、吴茱萸7g、桂枝7g、郁李仁13g、香橼5g、细辛5g、透骨草13g、鸡内金13g、枇杷叶12g、砂仁8g、乌梅6g、陈皮9g、半枝莲23g、炒草果仁5g、山楂10g、丁香4g。
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