CN105617290A - Application of medicinal composition in preparing medicine for promoting circulation and removing stasis - Google Patents

Application of medicinal composition in preparing medicine for promoting circulation and removing stasis Download PDF

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Publication number
CN105617290A
CN105617290A CN201610193551.3A CN201610193551A CN105617290A CN 105617290 A CN105617290 A CN 105617290A CN 201610193551 A CN201610193551 A CN 201610193551A CN 105617290 A CN105617290 A CN 105617290A
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parts
pharmaceutical composition
turmeric
prepared
radix
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刘学键
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Yantai Huawen Xinxin Pharmaceutical Co Ltd
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Yantai Huawen Xinxin Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
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    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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Abstract

The invention discloses application of a medicinal composition in preparing a medicine for promoting circulation and removing stasis, and belongs to the technical field of traditional Chinese medicines. The medicinal composition is prepared from the following traditional Chinese medicines: folium artemisiae argyi, salvia miltiorrhiza, angelica sinensis, paeonia lactiflora, ligusticum wallichii, corydalis tuber, curcuma aromatic, turmeric, frankincense, myrrh, trogopterus dung, curcuma zedoary, rhizoma sparganii, cattail pollen and liquorice. The medicinal composition disclosed by the invention has effects of warming and activating meridian, dispelling cold and removing stasis, relieving pain, dissipating stasis, and regulating menstruation and relieving pain in the aspect of circulation promotion and stasis movement, and has advantages of simple preparation process, good treatment effect, low side effect, convenience in taking, easiness in popularization and application, and the like.

Description

A kind of pharmaceutical composition is in the application prepared in activating blood and removing stasis drug
The application is that (denomination of invention is the application for a patent for invention that proposes of the joyful Pharmaceutical Technology Co., Ltd of Chinese of applicant Yantai City: a kind of pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon, application number is: 201610147657X, and the applying date is: on March 16th, 2016) point case application.
Technical field
The invention belongs to technical field of traditional Chinese medicines, it relates to a kind of pharmaceutical composition is in the application prepared in activating blood and removing stasis drug.
Background technology
Promoting blood circulation and removing blood stasis refer to by the method that there is dissipation role maybe can attack the pharmacological agent hemostasis disease by hemostasis in body. The visceral dysfunction that various different reason causes or because external force makes local blood vessels obstructed, all can cause hematogenous blockage in a certain position of human body or tissue, thus cause pain even to form the structural changes such as swollen block.
Chinese medicine is promoting blood circulation and removing blood stasis is a kind of comprehensively regulating effect, adjustable function, dredging blood vessel, and eliminate pain makes diseased region recover normal. Promoting blood circulation and removing blood stasis have that unobstructed blood vessels, the dissipation stasis of blood are stagnant, the effect of menstruction regulating and pain relieving, applied widely, if stasis blocking is in uncomfortable in chest pained, the cyanotic lips caused by the heart; Stasis blocking is in the pectoralgia hemoptysis caused by lung; Stasis blocking is in the hypochondriac pain lump in the abdomen caused by liver; Stasis blocking is ached in the underbelly caused by uterus, menoxenia, dysmenorrhoea etc.; Stasis blocking is livid purple in the partial gall caused by limbs; Stasis blocking is in the hemiplegia etc. caused by train of thought. The medicine composition prescriptions such as conventional Ligusticum wallichii, peach kernel, safflower, the radix paeoniae rubrathe, the red sage root, cattail pollen, frankincense, myrrh, represent prescription and have peach kernel CHENGQI TANG, decoction for removing blood stasis, post-equalization blood activating decoction and decoction for warming channels etc., normal same tonifying Qi promoting blood circulation and removing blood stasis, nourish blood, warming channel and expelling cold, heat-clearing, promoting the circulation of qi and capture etc. therapy with the use of.
Chinese patent application 200910145012.2 discloses a kind of Chinese medicine promoting blood circulation and removing blood stasis, and this Chinese medicine is made up of following raw material: Radix Astragali 25-35g; Radix Angelicae Sinensis 25-35g; Tree Peony Bark 25-35g; Cassia twig 25-35g; Radix paeoniae rubrathe 25-35g; White tuckahoe 25-35g; Rhizoma Sparganii 25-35g; Curcuma zedoary 25-35g; Raw peach kernel 25-35g; Safflower 25-35g; Unprocessed leech 45-55g and Concha Ostreae 45-55g. This Chinese medicine has function promoting blood circulation and removing blood stasis, promoting QI to circulate and dispersing the agglomeration of the pathogens, evident in efficacy in treatment hysteromyoma and ovarian cysts, but the action period is long, cures the symptoms, not the disease, and can not alleviate patient painful in the short period of time.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of pharmaceutical composition in the application preparing in activating blood and removing stasis drug, described pharmaceutical composition is in promoting blood circulation and removing blood stasis, pointed advantage strong, rapid-action, evident in efficacy, meanwhile, the present invention also provides the preparation method of a kind of described pharmaceutical composition.
The pharmaceutical composition that the present invention has function promoting blood circulation and removing blood stasis is prepared from by the raw material of following weight part: tarragon 5-25 part, red sage root 9-15 part, Radix Angelicae Sinensis 6-15 part, radix paeoniae rubrathe 6-12 part, Ligusticum wallichii 6-12 part, Yanhusuo 3-9 part, root tuber of aromatic turmeric 3-9 part, turmeric 3-9 part, frankincense 3-9 part, myrrh 3-9 part, Trogopterus Dung 6-12 part, curcuma zedoary 6-12 part, Rhizoma Sparganii 3-9 part, cattail pollen 3-9 part and Radix Glycyrrhizae 1-10 part.
Further, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
Correspondingly, the present invention also provides the preparation method of described pharmaceutical composition, comprises following processing step: takes above-mentioned Chinese medicinal materials and is broken into meal, the ethanolic soln that volumetric concentration is 40%-95% is doubly added according to the 4-9 of meal gross weight, refluxing extraction 2-3 time, return time is 2-5h, filters, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80-100 order sieve, obtain pharmaceutical composition of the present invention.
Further, in Chinese medicine material medicine fine powder, add suitable auxiliary material, make clinical required formulation with modern Chinese herbal medicine preparation common process, such as capsule, tablet, powder, granule, oral liquid or pill.
Source, the nature and flavor of each component of pharmaceutical composition of the present invention, return through and effect:
Tarragon: this product is the dry leave of feverfew Chinese mugwort; Taste is pungent, bitter, warm in nature; Return liver, spleen, kidney channel; Dispersing cold for relieving pain, warming the meridian for stopping bleeding.
The red sage root: this product is the dry root and rhizome of the labiate red sage root; Bitter, cold nature; The thoughts of returning home, Liver Channel; Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.
Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica; Taste is sweet, pungent, warm in nature; Return liver, the heart, the spleen channel; Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, relax bowel.
The radix paeoniae rubrathe: this product is ranunculaceae plant Chinese herbaceous peony or the dry root of the river radix paeoniae rubrathe; Bitter, cold nature; Return Liver Channel; Clearing heat and cooling blood, blood stasis removing analgesic.
Ligusticum wallichii: this product is the dry rhizome of samphire Ligusticum wallichii; Taste is pungent, warm in nature; Return liver, courage, pericardium warp; Blood-activating and qi-promoting, wind-expelling pain-stopping.
Yanhusuo: this product is the dry tuber of papaveraceae plant corydalis; Taste is pungent, bitter, warm in nature; Return liver, the spleen channel; Invigorate blood circulation, profit gas, pain relieving.
Root tuber of aromatic turmeric: this product is the dried root of zingiberaceous plant RADIX CURCUMAE, turmeric, Guangxi zedoary or zddoary; Taste is pungent, bitter, cold in nature; Return liver, the heart, lung channel; Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.
Turmeric: this product is the dry rhizome of zingiberaceous plant turmeric; Taste is pungent, bitter, warm in nature; Return spleen, Liver Channel; Broken blood gas, inducing meastruation to relieve menalgia.
Frankincense: this product is Bursera family Boswellia carterii platymiscium Boswellia carterii, medicine glue Xiang Shu and wild Boswellia carterii etc., is used as medicine with the oleo-gum-resin that its trunk skin zone wound oozes out; Taste is pungent, bitter, warm in nature; Promoting blood circulation and stopping pain.
Myrrh: Bursera family bdellium plant myrrh and belong to the oleo-gum-resin that the trunk skin zone of his kind of plant oozes out together; Bitter, property is put down; Blood stasis removing analgesic, externally used detumescence myogenic.
Trogopterus Dung: this product is flying squirrel section animal orange foot flying squirrel or the dry ight soil flying the little flying squirrel of murine; Taste is sweet, warm in nature; Promoting blood circulation to remove blood stasis, fries charcoal hemostasis.
Curcuma zedoary: this product is the dry rhizome of zingiberaceous plant zddoary, Guangxi zedoary or RADIX CURCUMAE; Taste is pungent, bitter, warm in nature; Return liver, the spleen channel; Blood is broken in promoting the circulation of qi, and disappear long-pending pain relieving.
Rhizoma Sparganii: this product is the dry tuber of the black Rhizoma Sparganii of Sparganiaceae plant; Taste is pungent, bitter, and property is put down; Return liver, the spleen channel; Broken blood gas, disappear long-pending pain relieving.
Cattail pollen: this product is the dry pollen of the cattail section turbid cattail of vegetation water, east cattail or congener; Taste is sweet, and property is put down; Return liver, pericardium warp; Hemostasis, stagnation resolvation, treating stranguria.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, glycyrrhiza inflate bat or glycyrrhiza glabra; Taste is sweet, and property is put down; The thoughts of returning home, lung, spleen, stomach warp; Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The compatibility analysis of pharmaceutical composition prescription of the present invention:
Pharmaceutical composition prescription of the present invention to dialectical cognition promoting blood circulation and removing blood stasis according to the traditional Chinese medical science, is followed the compatibility theory of Chinese medicine, in order to make the preparation facilitating easy-to-use and stable curative effect, is enhanced the usage quantity of medicinal material. This prescription is with tarragon, the red sage root and ought be classified as monarch's medicine, stasis-dispelling and pain-killing, promoting blood circulation and removing blood stasis; Taking curcuma zedoary, Yanhusuo, root tuber of aromatic turmeric, the radix paeoniae rubrathe and turmeric as ministerial drug, promoting blood circulation and stopping pain, blood stasis removing analgesic and detumescence myogenic; Taking Rhizoma Sparganii, frankincense, Ligusticum wallichii, Trogopterus Dung and myrrh as adjutant, regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, the broken blood of promoting the circulation of qi and the long-pending pain relieving that disappears; Taking cattail pollen and Radix Glycyrrhizae as making medicine, the coordinating the actions of various ingredients in a prescription property of medicine, all medicines coordinate, and complement each other, and synergy, has very significant curative effect in promoting blood circulation and removing blood stasis.
Compared with prior art, the present invention has following technical superiority:
1. pharmaceutical composition of the present invention has stasis-dispelling and pain-killing, promoting blood circulation and removing blood stasis and detumescence effect such as myogenic, also has that preparation technology is simple, good effect, side effect are low, easy administration and be easy to advantages such as applying;
2. compared with chemotherapeutic agent currently promoting blood circulation and removing blood stasis, pharmaceutical composition thing of the present invention is that natural pure Chinese medicinal preparation, untoward reaction and side effect significantly reduce, and pharmaceutical composition thing effect of the present invention is comprehensive, and medication effect is better;
3. pharmaceutical composition of the present invention is in the clinical experiment for the treatment of qi stagnation and blood stasis type chloasma, the efficiency that always has for the treatment of qi stagnation and blood stasis type chloasma is 96.67%, what be significantly higher than conventional medicine toxin-discharging nourishing capsule always has efficiency 66.67%, therefore medicine composite for curing qi stagnation and blood stasis type chloasma effect of the present invention is remarkable, can be used as drug use promoting blood circulation and removing blood stasis, clinical generalization value height.
Embodiment
The present invention is further described below by way of specific embodiment, the present invention is not limited only to following examples, within the scope of the invention or not departing from the content of the present invention, spirit and scope, change, combination or the replacement that the present invention is carried out, it is apparent for a person skilled in the art, and it is included within the scope of the present invention.
Embodiment 1
Embodiment 1 pharmaceutical composition is made up of the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
Preparation method is as follows: gets the above-mentioned Chinese medicinal materials of recipe quantity and is broken into meal, add, according to 4 times of meal gross weight, the ethanolic soln that volumetric concentration is 50%, refluxing extraction 3 times, return time is 3h, filter, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80 order sieves, obtain pharmaceutical composition of the present invention, Chinese medicine material medicine fine powder adds suitable capsule auxiliary material, makes capsule with modern Chinese herbal medicine preparation common process.
Embodiment 2
Embodiment 2 pharmaceutical composition is made up of the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
Preparation method is as follows: gets the above-mentioned Chinese medicinal materials of recipe quantity and is broken into meal, add, according to 5 times of meal gross weight, the ethanolic soln that volumetric concentration is 70%, refluxing extraction 3 times, return time is 3h, filter, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80 order sieves, obtain pharmaceutical composition of the present invention, Chinese medicine material medicine fine powder adds suitable capsule auxiliary material, makes capsule with modern Chinese herbal medicine preparation common process.
Embodiment 3
Embodiment 3 pharmaceutical composition is made up of the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 2.
Embodiment 4
Embodiment 4 pharmaceutical composition is made up of the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 2.
The clinical efficacy of medicine composite for curing qi stagnation and blood stasis type chloasma of the present invention
1, case data: all experimenters are the qi stagnation and blood stasis type clinical volunteer patient of chloasma women, totally 270 example, it is divided into test 1 group at random, tests 2 group and control group, often organize each 90 examples, test patient age 23-48 year in 1 group, year mean age (28.3 �� 4.1), the course of disease 8 months-9 years, average course of disease (3.7 �� 2.7) year; Test patient age 25-45 year in 2 groups, year mean age (27.5 �� 3.8), the course of disease 7 months-10 years, average course of disease (3.5 �� 3.0) year; Patient age 21-46 year in control group, year mean age (29.1 �� 4.4), the course of disease 10 months-9 years, average course of disease (3.5 �� 2.8) year. Through confirm, participate in this research all patients all meet Case definition and with following symptom: there is tawny patch in face, soreness of the waist and knees, or being irritable and getting angry easily, distending pain in the chest and hypochondrium; Dark tongue quality, white and thin fur, deep-thready pulse. Experimenter all makes a definite diagnosis as patient with chloasma, and get rid of other serious change and medicine contraindication patient, meet the primary condition of this research, the physical data no significant differences such as age of three groups of patients, the course of disease, P > 0.05, difference does not have statistical significance, can carry out good comparison and analysis between group.
2, test method:
Control group: oral toxin-discharging nourishing capsule (the accurate word Z53020685 of traditional Chinese medicines, Yunnan interwined dragon sea of clouds pharmaceutcal corporation, Ltd), one time 2, every day 2 times;
Test 1 group: the obtained capsule of the oral embodiment of the present invention 3, every day 2 times, each 3;
Test 2 groups: the obtained capsule of the oral embodiment of the present invention 4, every day 2 times, each 3;
Three groups, all taking 4 weeks as a course for the treatment of, judge curative effect after treating 1 course for the treatment of, and between medication period, many drinking waters fruit, vegetables, drink boiled water more, and fasting or few edible oil explode, pungent irritating food.
3, criterion of therapeutical effect:
The chloasma criterion of therapeutical effect of revision in 2003 is organized with reference to the Dermatology specialty council of combination of Chinese tradiational and Western medicine association of China pigment disease.
Cure: naked eyes disappear depending on color spot area and are greater than 90%, and color disappears substantially;
Effective: meat is greater than 60% with disappearing depending on color spot area, and color obviously becomes light;
Effective: naked eyes disappear depending on color spot area be greater than 30%. colors become light;
Invalid: naked eyes disappear depending on color spot area and are less than 30%, color change is not obvious.
Always there is efficiency=(healing+effective+effective)/total number of cases �� 100%
4, clinical test results is in table 1:
Table 1 takes Chinese medicine composition of the present invention and the observation of curative effect taking routine medication chloasma
The treatment test 1 group, testing 2 group always has efficiency to be respectively 96.7% and 95.6%, obviously always there is efficiency higher than control group, and test 1 group, test 2 and group untoward reaction does not all occur, show to use medicine composite for curing qi stagnation and blood stasis type chloasma curative effect of the present invention definite, safe and reliable, can be used as the effective ways for the treatment of qi stagnation and blood stasis type chloasma.

Claims (6)

1. a pharmaceutical composition is in the application prepared in activating blood and removing stasis drug, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5-25 part, red sage root 9-15 part, Radix Angelicae Sinensis 6-15 part, radix paeoniae rubrathe 6-12 part, Ligusticum wallichii 6-12 part, Yanhusuo 3-9 part, root tuber of aromatic turmeric 3-9 part, turmeric 3-9 part, frankincense 3-9 part, myrrh 3-9 part, Trogopterus Dung 6-12 part, curcuma zedoary 6-12 part, Rhizoma Sparganii 3-9 part, cattail pollen 3-9 part and Radix Glycyrrhizae 1-10 part.
2. pharmaceutical composition as claimed in claim 1 is in the application prepared in activating blood and removing stasis drug, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
3. pharmaceutical composition as claimed in claim 1 is in the application prepared in activating blood and removing stasis drug, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
4. pharmaceutical composition as claimed in claim 1 is in the application prepared in activating blood and removing stasis drug, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
5. pharmaceutical composition as claimed in claim 1 is in the application prepared in activating blood and removing stasis drug, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
6. pharmaceutical composition as described in item as arbitrary in claim 1-5 is in the application prepared in activating blood and removing stasis drug, it is characterised in that, described pharmaceutical composition obtains by the following method: takes recipe quantity traditional Chinese medicinal material raw materials and is broken into meal, the ethanolic soln that volumetric concentration is 40%-95% is doubly added according to the 4-9 of meal gross weight, refluxing extraction 2-3 time, return time is 2-5h, filters, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80-100 order sieve, obtain pharmaceutical composition.
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CN110876788A (en) * 2019-09-26 2020-03-13 遵义红花岗刘端方医院(普通合伙) Traditional Chinese medicine for promoting blood circulation and relieving pain and preparation method thereof

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CN108434397B (en) * 2018-05-07 2021-06-11 中国医学科学院药用植物研究所 A medicated moxa stick for skin care
CN110327441A (en) * 2019-06-18 2019-10-15 山东中医药大学第二附属医院 A kind of Chinese medicine line spices directly acting on body surface and preparation method
CN111329935B (en) * 2020-04-14 2021-09-24 浙江沃野神生物科技有限公司 Traditional Chinese medicine freckle-removing composition and preparation method and application thereof

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CN110876788A (en) * 2019-09-26 2020-03-13 遵义红花岗刘端方医院(普通合伙) Traditional Chinese medicine for promoting blood circulation and relieving pain and preparation method thereof

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