CN104338043B - A kind of medicine for improving immunity and preparation method thereof - Google Patents

A kind of medicine for improving immunity and preparation method thereof Download PDF

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Publication number
CN104338043B
CN104338043B CN201410628720.2A CN201410628720A CN104338043B CN 104338043 B CN104338043 B CN 104338043B CN 201410628720 A CN201410628720 A CN 201410628720A CN 104338043 B CN104338043 B CN 104338043B
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parts
fruit
volatile oil
medicine
preparation
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CN104338043A (en
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刘尚义
唐东昕
杨柱
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Guizhou University of Traditional Chinese Medicine
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Guiyang College of Traditional Chinese Medicine
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of pharmaceutical composition for improving immunity, the medicine is by the Radix Astragali, the bighead atractylodes rhizome, it is windproof, suncured white ginseng root, Yun Ling, Chinese yam, sealwort, mulberries, Radix Angelicae Sinensis, gynostemma pentaphylla, Nan Buzheng, cynanchum wilfordii, the fruit of glossy privet, Eclipta prostrata, the dried rhizome of rehmannia, cultivated land, Semen Cuscutae, saline cistanche, matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw jujube kernel, ripe jujube kernel, grass-leaved sweetflag, polygala, light wheat, deer horn glue, tortoise-shell glue, donkey-hide gelatin, golden cypress, the wind-weed, charred FRUCTUS CRATAEGI, notopterygium root, levisticum, Ligusticum wallichii prescription, with consolidating superficial resistance and supplementing qi, tonifying vital QI, Tianjing Busuiye medicinal, the effect of strengthening vital QI to eliminate pathogenic factors, energy strengthen immunity, strengthen physical function;Suitable for frequent sick, recurrent exerbation, the patient of hypoimmunity, manufactured curative effect of medication is notable, has no toxic side effect.

Description

A kind of medicine for improving immunity and preparation method thereof
Technical field
The present invention relates to a kind of medicine for improving immunity(Also known as cream is built admittedly)And preparation method thereof, belong to medicine technology Field.
Background technology
Modern industrial society, environment, food, air, domestic water is all different degrees of to be contaminated, and we live in soon In the environment of rhythm, in life all the time test our health, the crowd of particularly present city white collar's inferior health More and more, the middle pressure that usually works is big, and overtime work is more, and free time is fewer and fewer, and many city white collars do not have time motion, warp Normal overtime work of staying up late.Work hours sitting, it is long-term against computer.Usually diet does not have rule, and not timing is had a meal, partial eclipse, and excessive drinks Coffee.These can make our immunity degradations so as to cause us to have a delicate constitution, malnutritive, One's spirits are drooping, fatigue and weak, The common diseases such as appetite reduction, sleep-disorder.Therefore the health for improving immunity to us is critically important.
Immunity is the defense mechanism of human body itself, is human bioequivalence and any foreign matter of the external intrusion of elimination(It is viral, thin Bacterium etc.), processing aging, damage, death, the own cells of denaturation and identification and processing vivo mutations cell and virus are infected thin The ability of born of the same parents.Want it is few sick in usually living, it is energetic during work, it is necessary to which that the immunity resistance for improving itself is extraneous Invasion.Improve immunity in conventional pharmacy is all that health care is mainly vitamin, and albumen powder class, these health products all can only office The solution inferior health problem in portion, for hypoimmunity caused by single aspect.Many times we do not know about oneself immunity The reason for low, it is able to eat and states health products and can not suit the remedy to the case at all, a kind of extensive medicine for hypoimmunity is just very urgent It is essential and wants, this medicine can adjusts each function of our bodies well, comprehensively nurse one's health our body.Promote ours Immunity is improved.
The content of the invention
It is an object of the invention to provide a kind of medicine for improving immunity(Also known as cream is built admittedly)And preparation method thereof.It is described Medicine has the effect of consolidating superficial resistance and supplementing qi, tonifying vital QI, Tianjing Busuiye medicinal, strengthening vital QI to eliminate pathogenic factors.Supported suitable for losing inadequate natural endowment, the day after tomorrow, long Disease it is not multiple and show easy to catch cold, food intake reduction, loose stool abdominal distension, fatigue in both spirit and physical strength, aversion to cold and cold limbs, soreness and weakness of waist and knees, impotence and premature ejaculation, The diseases such as woman is infertile with, enuresis nocturna frequency.Suitable for frequent sick, recurrent exerbation, the patient of hypoimmunity.Apply also for Asia Healthy population, city white collar, clerk, there is precancerous lesion symptom.
To solve above technical problem, the present invention is realized using following technical scheme:
A kind of medicine for improving immunity, is calculated according to composition by weight, by Radix Astragali 20-80 parts, bighead atractylodes rhizome 20-70 parts, windproof 10-50 parts, suncured white ginseng root 50-200 parts, Yun Ling 20-80 parts, Chinese yam 20-80 parts, sealwort 20-80 parts, mulberries 20-80 parts, Radix Angelicae Sinensis 20-70 parts, gynostemma pentaphylla 20-70 parts, the positive 20-70 parts of southern cloth, cynanchum wilfordii 10-50 parts, fruit of glossy privet 20-70 parts, Eclipta prostrata 20-70 Part, dried rhizome of rehmannia 20-80 parts, cultivated land 20-80 parts, Semen Cuscutae 20-80 parts, saline cistanche 20-80 parts, matrimony vine 20-70 parts, RADIX POLYGONI MULTIFLORI PREPARATA 20- 80 parts, it is HERBA EPIMEDII 20-70 parts, thizoma curculiginis 20-70 parts, fruit of Chinese magnoliavine 20-70 parts, Polygonum multiflower knotweed 10-50 parts, raw jujube kernel 10-50 parts, ripe Jujube kernel 10-50 parts, grass-leaved sweetflag 10-50 parts, polygala 5-30 parts, light wheat 20-80 parts, deer horn glue 10-40 parts, tortoise-shell glue 10-40 Part, donkey-hide gelatin 10-40 parts, golden cypress 10-40 parts, wind-weed 10-40 parts, charred FRUCTUS CRATAEGI 10-50 parts, notopterygium root 5-30 parts, levisticum 5-30 parts, river Rhizome of chuanxiong 5-30 parts and auxiliary material are prepared.
Specifically, a kind of medicine for improving immunity calculates according to composition by weight, by 50 parts of the Radix Astragali, 40 parts of the bighead atractylodes rhizome, prevents 30 parts of wind, 100 parts of suncured white ginseng root, 50 parts of Yun Ling, 50 parts of Chinese yam, 50 parts of sealwort, 50 parts of mulberries, 40 parts of Radix Angelicae Sinensis, 40 parts of gynostemma pentaphylla, south Cloth is positive 40 parts, 30 parts of cynanchum wilfordii, 40 parts of the fruit of glossy privet, 40 parts of Eclipta prostrata, 50 parts of the dried rhizome of rehmannia, 50 parts of cultivated land, 50 parts of Semen Cuscutae, saline cistanche 50 parts, 40 parts of matrimony vine, 50 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 40 parts of HERBA EPIMEDII, 40 parts of thizoma curculiginis, 40 parts of the fruit of Chinese magnoliavine, 30 parts of Polygonum multiflower knotweed, raw jujube kernel 30 Part, 30 parts of ripe jujube kernel, 30 parts of grass-leaved sweetflag, 20 parts of polygala, 50 parts of light wheat, 25 parts of deer horn glue, 25 parts of tortoise-shell glue, 25 parts of donkey-hide gelatin, 25 parts of golden cypress, 25 parts of the wind-weed, 30 parts of charred FRUCTUS CRATAEGI, 15 parts of notopterygium root, 15 parts of levisticum, 20 parts of Ligusticum wallichii and auxiliary material are prepared.
It is described improve immunity the preparation method of medicine be:Proportionally weigh the Radix Astragali, the bighead atractylodes rhizome, windproof, suncured white ginseng root, cloud Siberian cocklebur, Chinese yam, sealwort, mulberries, Radix Angelicae Sinensis, gynostemma pentaphylla, Nan Buzheng, cynanchum wilfordii, the fruit of glossy privet, Eclipta prostrata, the dried rhizome of rehmannia, cultivated land, Semen Cuscutae, meat Desert cistanche, matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw jujube kernel, ripe jujube kernel, grass-leaved sweetflag, polygala, light wheat, Acceptable pharmaceutic adjuvant in deer horn glue, tortoise-shell glue, donkey-hide gelatin, golden cypress, the wind-weed, charred FRUCTUS CRATAEGI, notopterygium root, levisticum and Ligusticum wallichii and medicine It is combined, and is processed according to the preparation method of routine, corresponding pharmaceutical preparation is made.
Specifically, the preparation method of the medicine for improving immunity is:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, river Rhizome of chuanxiong extracts 0.5-2h using steam distillation, collects condensate liquid, stratification, isolates volatile oil, standby;Extract volatile oil After the dregs of a decoction afterwards mix with remaining medicinal material, add the 6-8 times of decocting measured and boil 2-3 times, each 0.5-2h, decocting liquid filtering three times, close And medicinal extract is condensed into, above-mentioned volatile oil is added, is mixed with conventional pharmaceutical adjuvants, different medicines is made according still further to conventional method Preparation.
More specifically, it is described improve immunity medicine preparation method, take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, river Rhizome of chuanxiong extracts 1h using steam distillation, collects condensate liquid, stratification, isolates volatile oil, standby;After extracting volatile oil After the dregs of a decoction mix with remaining medicinal material, add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition, 8 times of amount decoctings Boil 1 hour, third time adds 6 times of amount decoctings and boiled 0.5 hour, collecting decoction, relative density when being condensed into 60-65 DEG C 1.10-1.15 medicinal extract, above-mentioned volatile oil is added, is mixed with conventional pharmaceutical adjuvants, different medicines is made according still further to conventional method Thing preparation.
The pharmaceutical preparation be soft extract, hard capsule, ointment, tablet, granule, pill, oral liquid, syrup, Powder, sublimed preparation, supensoid agent, solution, parenteral solution, freeze-dried powder, high-capacity injection, suppository, emplastrum, creme, spray Or patch.Specially:Soft extract, capsule, granule or oral liquid.
The soft extract is prepared:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, glossy privet Son, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are extracted using steam distillation 1h, condensate liquid is collected, stratification, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, Add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition, 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times Amount decocting boil 0.5 hour, collecting decoction, when being condensed into 60-65 DEG C the medicinal extract for the 1.10-1.15 that relative density is, addition be made The honey of amount 20%, agitating and heating, relative density is 1.2-1.25 medicinal extract when being concentrated into 60-65 DEG C, adds above-mentioned volatilization Oil mixes, and produces.
The capsule is prepared:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, glossy privet Son, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are extracted using steam distillation 1h, condensate liquid is collected, stratification, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, Add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition, 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times Amount decocting is boiled 0.5 hour, collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, is added above-mentioned Volatile oil and the dextrin of the amount of being made 10% and 0.5% magnesium stearate are well mixed, and with 65% alcohol granulation, are dried, whole grain, Capsule is loaded, is produced.
The granule is prepared:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, glossy privet Son, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are extracted using steam distillation 1h, condensate liquid is collected, stratification, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, Add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition, 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times Amount decocting is boiled 0.5 hour, collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, is added above-mentioned The dextrin and the mixing of 15% sucrose of volatile oil and the amount of being made 15% mix, and are that wetting agent makes pellet with 85% ethanol, 60 DEG C dry It is dry, after 12 mesh sieve 1 time, and fine powder is separated with 60 mesh sieves, produced.
The oral liquid is prepared:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, glossy privet Son, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are extracted using steam distillation 1h, condensate liquid is collected, stratification, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, Add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition, 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times Amount decocting boil 0.5 hour, collecting decoction, when being condensed into 60-65 DEG C the medicinal extract for the 1.10-1.15 that relative density is, addition be made The honey of amount 10%, and the sodium benzoate of the amount of being made 0.2%, boil dissolving, add above-mentioned volatile oil and mix, add pure water Full dose is settled to, is stirred evenly, filters, embedding, produces oral liquid.
Medicine of the present invention is by the Radix Astragali, the bighead atractylodes rhizome, windproof, suncured white ginseng root, Yun Ling, Chinese yam, sealwort, mulberries, Radix Angelicae Sinensis, strand Indigo plant, Nan Buzheng, cynanchum wilfordii, the fruit of glossy privet, Eclipta prostrata, the dried rhizome of rehmannia, cultivated land, Semen Cuscutae, saline cistanche, matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, HERBA EPIMEDII, celestial being Thatch, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw jujube kernel, ripe jujube kernel, grass-leaved sweetflag, polygala, light wheat, deer horn glue, tortoise-shell glue, donkey-hide gelatin, golden cypress, know Mother, charred FRUCTUS CRATAEGI, notopterygium root, levisticum, Ligusticum wallichii and auxiliary material are prepared.Wherein, the Radix Astragali is the root that the Papillionoideae Radix Astragali is dried, sweet, Tepor, return lung, spleen, liver and kidney channel, for hypertension, ischemic heart, acute glomerulonephritis, helicobacter pylori positive stomach Ulcer, psoriasis, diabetes, rhinitis chronic, matter are loose.The bighead atractylodes rhizome is the rhizome that the feverfew bighead atractylodes rhizome is dried, bitter, sweet, warm-natured, is returned Spleen, stomach, strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis is antiabortive, for spleen eating less, abdominal distention diarrhea, and phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, Fetal irritability, invigorating the spleen, and stomach, it is antiabortive.The windproof rhizome dried for umbelliferae Saposhnikovia divaricata.Pungent, sweet, tepor, return bladder warp, lung Through, the spleen channel, Liver Channel, it is windproof to expel pathogenic wind from the body surface, be expel endogenous wind to relieve convulsion, spasmolysis, antipruritic, for bodily pain of catching cold, have a headache, arthralgia pain due to rheumatism, Skeletal pain, stomachache diarrhea, discharging fresh blood stool, lockjaw, rubella itch.Suncured white ginseng root is made for the fresh whole epidermises of ginseng are scraped off into drying Into, sweet, slight bitter, temperature, mild-natured, tepor, sweet, slight bitter, returns spleen, lung channel, the heart channel of Hang-Shaoyin, tonifying Qi, prevent prolapse, promote the production of body fluid, calm the nerves, intelligence development, To be taken off for physically weak, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung is breathed with cough, injury thirst, Heat Diabetes, and prolonged illness void is thin, insomnia of palpitating with fear, Impotence Gong Leng;Heart failure, cardiogenic shock.Cloud Siberian cocklebur also known as Poria cocos, it is the dry sclerotia of Polyporaceae Poria cocos, it is sweet, light, flat, The thoughts of returning home, spleen, kidney channel, for clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative.Chinese yam is Dioscoreaceae plant Chinese yam Dioscorea Opposita Thunb. dry rhizome, sweet, flat, nontoxic, returns spleen, lung, kidney channel, for tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying Puckery essence, spleen eating less, endless diarrhea, the deficiency syndrome of the lung are breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.Sealwort is(Scientific name: Polygonatum sibiricum), it is the root that sealwort section plant sealwort is dried, for tonifying spleen, moistening lung and production of body fluid, Ligusticum wallichii(Scientific name: Ligusticum chuanxiong hort), it is the root that a kind of Chinese medicinal plant is dried, acrid flavour is warm-natured, Return liver, courage, the heart channel of Hang-Shaoyin, gas Perfume, which rises, to be dissipated, blood-activating and qi-promoting, wind-expelling pain-stopping, for irregular menstruation, dysmenorrhoea, Amenorrhea, difficult labour, placenta retension, lochia stomachache, is swollen Block, heart pain in chest and hypochondrium, traumatic injury swelling and pain, dizziness of having a headache mesh is dark, wind-cold-dampness arthralgia, extremity numbness, ulcer sores.Mulberries are mulberry The ripening fruits of section deciduous tree mulberry tree, it is sweet, sour, cold in nature, return liver and kidney channel, the dizzy mesh lost for kidney deficiency and liver and deficiency of blood essence It is dizzy, soreness of waist tinnitus, poliosis, insomnia and dreamful sleep, injury thirst, quench one's thirst, dry constipation of intestines.Dried when being classified as umbelliferae angelica Root, sweet, pungent, warm, Return liver, the heart, the spleen channel, gather for all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, abdominal mass knot, uterine bleeding, the cold of insufficiency type Stomachache, Impotence numbness, numbness, intestines are dry and shit is difficult, weight, ulcer sores, injury from falling down after dysentery characterized by blood in the stool.Gynostemma pentaphylla is cucurbitaceous plant strand The blue drying herb of stock, hardship, micro-sweet, cool, return lung, spleen, kidney channel, for physically weak weak, nephrasthenia emission, leukopenia, height Pionemia, virus hepatitis, chronic gastroenteritis, chronic bronchitis.Nan Buzheng also known as Chinese avens herb or root, it is rosaceous plant pubescence The herb of yellow avens, bitter, acrid, cold, returns spleen, kidney, Liver Channel, for dizzy, child convulsion, impotence, seminal emission, cough due to consumptive disease, the wind of swooning Arthritis with fixed pain caused by dampness pain, irregular menstruation, sore swell and ache curative, traumatic injury.Cynanchum wilfordii also known as radix cynanchi bungei, it is the drying of Asclepiadaceae plant cynanchum wilfordii Root, bitter, sweet puckery, tepor is nontoxic, returns liver and kidney channel, for control prolonged illness weakness, chronic wandering arthritis, soreness and weakness of waist and knees, anaemia, enterorrhagia, Poliosis, neurasthenia, deficiency of Yin chronic malaria, ulcer do not close up long, old people constipation.The fruit of glossy privet is Oleaceae plants glossy privet Ligustrum lucidum Ait. dry mature fruit, it is sweet, bitter, flat, return liver and kidney channel, for Light-headedness, waist and knee acid It is soft, seminal emission, tinnitus poliosis, osteopyrexia and fever.Eclipta prostrata is composite family Eclipta prostrata plant drying herb, sweet acid, cool, enters liver and kidney channel, For nourishing liver and kidney, cooling blood and hemostasis, the diseases such as various haematemesis, enterorrhagia can be controlled;Smash juice and apply eyebrow hair, hair growth can be promoted, taken orally There are black hair, dark hair effect.The dried rhizome of rehmannia is the root tuber of scrophulariaceae rehmannia glutinosa plant, sweet, cold, the thoughts of returning home, liver and kidney channel, is entered for warm heat disease heat Ying blood, high fever coma, dry tongue are deep red.Cultivated land is scrophulariaceae rehmannia glutinosa plant(Scientific name:Rehmannia glutinosa)Drying Root, this product are its processed product, sweet, tepor, return liver and kidney channel, yin-nourishing of enriching blood, life essence-filling, marrow-benefitting.Semen Cuscutae is that Convolvulaceae Semen Cuscutae does Dry herb, pungent, sweet, tepor, Return liver, kidney, the spleen channel, for pain in the back tinnitus, impotence [4] seminal emission, quench one's thirst, infertility, enuresis incontinence, Under stranguria with turbid discharge band, the head is dim, deficiency of food diarrhea, fetal irritability.Saline cistanche is a kind of broomrape for colonizing in desert trees sacsaoul root Section's parasitic plant dry root, it is sweet, salty, warm, return kidney, large intestine channel, kidney-replenishing, benefiting essence-blood, ease constipation road, for decline of kidney-YANG, essence The impotence of blood deficiency, seminal emission, gonorrhoea, the frequent micturition heeltap, pain in the back flaccidity of lower limbs, tinnitus mesh flower, menstruation are spread out phase, fertility, dry constipation of intestines. Matrimony vine is plant of Solanaceae lycium barbarum Lycium barbarum L. dry mature fruit, sweet, is put down, and returns liver and kidney channel, nourishes liver Kidney, benefiting shrewd head, for consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, impotence and seminal emission, Heat Diabetes, blood deficiency chlorosis, blurred vision is not The illness such as bright.RADIX POLYGONI MULTIFLORI PREPARATA is polygonum multiflorum thunb Polygonum multiflorum Thunb. dried root, and this product is Its processed product, RADIX POLYGONI MULTIFLORI PREPARATA filling liver kidney, benefiting essence-blood, black beard and hair, strengthen the bone.HERBA EPIMEDII also known as barrenwort, it is the celestial spirit of Berberidaceae plant The drying herb of spleen is pungent, sweet, warm, returns liver and kidney channel, is declined for impotence and premature ejaculation, pain in low back and legs, numb limb, hemiplegia, nerve Weak, forgetful, tinnitus is dizzy.Thizoma curculiginis be bloodwort drying herb, tonify the kidney and support yang, benefiting essence-blood, strengthening the bones and muscles, promoting circulation of blood detumescence, For impotence cold sperm, aconuresis, coldness and pain in the epigastrium, soreness of waist and knee joint, muscles and bones is soft, lower limb contraction, menopausal syndrome.The fruit of Chinese magnoliavine is Magnoliaceae schisandra Schisandra chinensis(Turcz.)Or schisandra chinensis Schisandra Baill. Sphenanthera Rehd. et Wils. dry mature fruit, astringe the lung, nourshing kidney, promote the production of body fluid, receive sweat, puckery essence, for controlling the deficiency syndrome of the lung Breath with cough, thirst, spontaneous perspiration, night sweat, the thin thin, emission of internal lesion caused by overexertion, protracted dysentery and diarrhea.Polygonum multiflower knotweed is medicine polygonaceae plant Polygonum multiflower knotweed Dry root, sweet, slight bitter, flat, the thoughts of returning home, spleen, kidney, Liver Channel, for controlling insomnia, internal lesion caused by overexertion, hidrosis, deficiency of blood bodily pain, ulcer, scrofula, Wind sore scabies tinea.Raw jujube kernel is the fruit of Rhamnaceae jujube tree, sweet, sour, mild-natured, nourishes conscience, calms the nerves, arrest sweating, for deficiency of YIN-blood, Palpitation and severe palpitation, insomnia forgetfulness, body void hidrosis.Ripe jujube kernel is the dry fruit of Rhamnaceae jujube tree, sweet, sour, mild-natured, nourishing conscience, Calm the nerves, arrest sweating, for deficiency of YIN-blood, palpitation and severe palpitation, insomnia forgetfulness, body void hidrosis.Grass-leaved sweetflag is Araeceae, Acorus dogstail Drying herb, for dampness elimination appetizing, slit phlegm of having one's ideas straightened out, inducing resuscitation intelligence development is forgetful for gastral cavity ruffian is not hungry, apnea, coma epilepsy Deafness, qi-regulating, promoting blood circulation, wind is dissipated, is dried, control epilepsy, coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, abdomen Bitterly, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury.Polygala is milk wort polygala Polygala tenuifolia Willd. Or ovum leaf polygala Polygala sibirica L. dry root, bitter, pungent, temperature, the thoughts of returning home, kidney, lung channel, tranquilize the mind and promote the intelligence, the traffic heart Kidney, eliminating the phlegm, detumescence, for insomnia and dreamful sleep caused by breakdown of the normal physiological coordination between the heart and the kidney, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, Mastosis.Light wheat is the shrivelled frivolous caryopsis of grass wheat, Gan Xian, cool, and for hectic fever due to yin labor heat, only spontaneous perspiration is stolen Sweat.Deer horn glue is that the deer horn that stag has been ossify is endured through boiling, and solid gum is made in concentration, enriches blood, strengthening the essence, for deficiency of kidney-QI, void The thin thin, pain in the back of labor, cloudy subcutaneous ulcer, impotence in male, involuntary emission, uterus void are cold, uterine bleeding, band under.Tortoise-shell glue be tortoise plastron through decocting, Solid gum made of concentration, put down, Gan Xian, play the role of nourishing and suppressing Yang, replenishing kidney and strengthening bone, and it is simultaneous tonify the blood and arrest bleeding, for the deficiency of the kidney yin Caused osteopyrexia and fever, night sweat.Donkey-hide gelatin is the stabilized animal glue after donkey hide decocting and concentrating, sweet, puts down, return lung, liver and kidney channel, enriches blood, Hemostasis, nourishing Yin and moistening dryness, for nourishing yin and supplementing blood, antiabortive, through production disease gynaecology.Golden cypress is rutaceae wampee Phellodendron chinense Schneid. dry bark, it is bitter, tremble with fear, return kidney, bladder warp, there is heat-clearing and damp-drying drug, purging intense heat Except steaming, the effect of detoxification sore treatment.The wind-weed is the dry rhizome of the monocotyledon Liliaceae wind-weed, bitter, is trembled with fear.Return lung, stomach, kidney channel, For nourishing Yin and falling fire, moisturize laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin labor heat, cough with lung heat, dry feces, difficult urination.Charred FRUCTUS CRATAEGI is The fruit that rose family charred FRUCTUS CRATAEGI is dried, sour, sweet, tepor, returns spleen, stomach, Liver Channel are not well for meat stagnation, rush down dysentery.Notopterygium root is The root of Umbelliferae, notopterygium root plant drying, acrid, bitter, warm.Return bladder, kidney channel, for impotence and seminal emission, enuresis frequent micturition, waist and knee crymodynia, Deficiency of the kidney and dyspnea, Diarrhoea, external application curing vitiligo, alopecia areata, relieving exterior syndrome and dispelling cold, expelling wind and eliminating dampness, analgesic.Levisticum is samphire The dry root of Angelica pubescens, pungent, bitter, tepor, Return liver, kidney, bladder warp, expelling wind and eliminating dampness, eliminating cold to stop pain, for wind-cold-dampness arthralgia, Lumbocrural pain, few the moon volt wind headache, dentalgia of having a headache.Ligusticum wallichii is the dry root of samphire Ligusticum wallichii, pungent, temperature, Return liver, courage, the heart Through fragrant rise of gas dissipates, blood-activating and qi-promoting, wind-expelling pain-stopping, for irregular menstruation, dysmenorrhoea, Amenorrhea, difficult labour, placenta retension, lochia abdomen Bitterly, lump, heart pain in chest and hypochondrium, traumatic injury swelling and pain, dizziness of having a headache mesh is dark, wind-cold-dampness arthralgia, extremity numbness, ulcer sores.
The Fang Zhongyong Radixs Astragali, the bighead atractylodes rhizome, it is windproof be monarch, be the meaning for having Yupingfeng, refuse the six external factors which cause diseases in outer;With suncured white ginseng root, Poria cocos, mountain The day after tomorrow is mended in medicine, sealwort, mulberries, Radix Angelicae Sinensis, donkey-hide gelatin blood-enrich, training;With the fruit of glossy privet, Eclipta prostrata, raw cultivated land, Semen Cuscutae, saline cistanche, Matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, HERBA EPIMEDII, thizoma curculiginis, deer horn glue, tortoise glue Tianjing Busuiye medicinal, congenital help is all ministerial drug;With gynostemma pentaphylla, Nan Buzheng, every Mountain disappears, the hawthorn promoting flow of qi and blood circulation, and disperse accumulationsization is stagnant;With golden cypress, wind-weed heat-clearing, the flame gesture of reduction pungent-warm medicine;With light wheat, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw ripe jujube kernel, grass-leaved sweetflag, polygala mental-tranquilization, it is assistant that dormancy peace, which is covered with it,;With Qiang's levisticum, Ligusticum wallichii expelling wind drug blood medicine, band The efficacy of a drug pass through draw whole body up and down, face nine orifices, four limbs bones of the body collectively, nowhere less than with it to make.Honey is the essence of all sorts of flowers, coordinating the drug actions of a prescription, Defend tenaciously Middle Palace.All medicines play consolidating superficial resistance and supplementing qi, tonifying vital QI, Tianjing Busuiye medicinal, the work(of strengthening vital QI to eliminate pathogenic factors altogether.The solid table of we, train the day after tomorrow, mend first My god, if Yuanyang must mend, Kidney-Yin must support, body is inside and outside, solid fort, disease difficulty invades, it is sick must be cured, the feature of this side.
Contained medicinal material in prescription, the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Tu Contain volatile oil component in silk, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum and Ligusticum wallichii, if directly After decocting active ingredient volatile oil therein can vapor away, therefore the above-mentioned medicinal material of use extracts volatile oil with steam distillation, then The dregs of a decoction and remaining composition that extracted volatile oil are decocted extraction together.The effect of can ensure that medicine.
Applicant has carried out substantial amounts of research to the present invention, as follows:
Experimental example 1:Pharmacodynamic study
First, medicine of the present invention influences on spleen index and thymus index
1st, experimental animal:Kunming mouse, male and female half and half, 8 week old or so, body weight 25-30g.
2nd, Experimental agents:Medicine of the present invention(Prepared according to the method for the embodiment of the present invention 1).
3rd, test method:40 Kunming mouses (male and female half and half, 8 week old or so about 25-30g) stochastic averagina is divided into 4 groups, using gastric infusion (specific dosage and group technology are shown in Table 1), physiological saline of the control group to equivalent, administration 8 Zhou Hou, investigate influence of each group to immune organ.Inspection target is spleen index and thymus index, and both increases help to be immunized The raising of power, the results are shown in Table 1.
Note:With control group ratio, * P < 0.05, * * P < 0.001;
Conclusion:3 dosage of medicine of the present invention have difference (P < 0.05, the P < of statistical significance compared with control group 0.01).Prove that medicine of the present invention plays the role of spleen index and thymus index, and then improve immunity, body weight is influenceed little.
2nd, influence of the medicine of the present invention to mice serum hemolysin
1st, experimental animal:Mouse 50, the g of weight 18~22, male and female half and half.
2nd, trial drug:Medicine of the present invention(Prepared according to the method for the embodiment of the present invention 1), Liuwei Dihuang Wan(Beijing colleague Pharmaceutical factory of hall sci-tech development Co., Ltd.).
3rd, test method:By mouse be divided into reason saline control group, positive drug control group, medicine low dose group of the present invention, in Totally 5 groups of dosage group, high dose group (specific packet situation and dosage are shown in Table 2), every group 10.Adaptability is raised one After start to be administered.It is administered the 3rd day, the SR-BC sensitization of every mouse peritoneal injection 30%, 4 d after sensitization, last dose 1 Eyeball is plucked after h and takes blood, puts 1 h only, 3 000 r/min centrifuge 10 min, separate serum, for measure.Hemolysin is quantitatively surveyed It is fixed:The mL of serum 1.0 adds the mL of 30% SRBC 0.5, the mL of 10% complement 1.0 to enter reaction tube, put 37 after taking 100 times of dilution After DEG C water-bath is incubated 30 min, terminating reaction in ice-water bath is moved to, 2 000 r/min centrifuge 10 min, take supernatant 1 ML places 10 min, and absorbance is read at 540 nm.Experimental result is shown in Table 2.
Note:Compared with blank group, * P < 0.05, * * P < 0.001;
#P < 0.05, ##P < 0.001 compared with positive drug group.
Conclusion:3 dosage of medicine of the present invention have the difference (P < 0.05) of statistical significance compared with to blank group;Middle dose Amount and influence of the high dose to mice serum hemolysin are suitable with positive drug, and this is test result indicates that medicine of the present invention can strengthen The ability that mouse hemolysin is formed, it is prompted to improve antigen induction circulating antibody level, so as to realize the body fluid for improving body The effect of immunity.
Experimental example 2:Anxious malicious experimental study
1 experimental method
Kunming mouse, through prerun, give gavage of small white mouse medicine paste of the present invention(Method according to embodiment 1 is entered It is prepared by row)Equal 2mL/20g, does not cause death, and the concentration and administered volume for being limited to medicine can not increase, it is impossible to measure median lethal Measure (LD50), therefore carry out maximum tolerance determination experiment.
Select healthy Kunming mouse 20, weight (20 ± 2) g, gavage this in male and female half and half, with 24 hours points for 2 times Invention pharmaceutical composition paste, 2mL/ times, total amount reaches 100mL/kg, equivalent to 163 g/kg crude drugs.This dosage equivalent to 200 times of Coming-of-Age Day dosing.
2 experimental results
Mouse had no adverse reaction, whole bouncings, weight increase, no death to observation post administration 7 days.
Compared with prior art, the present invention from the Radix Astragali, the bighead atractylodes rhizome, windproof, suncured white ginseng root, Yun Ling, Chinese yam, sealwort, mulberries, when Return, gynostemma pentaphylla, Nan Buzheng, cynanchum wilfordii, the fruit of glossy privet, Eclipta prostrata, the dried rhizome of rehmannia, cultivated land, Semen Cuscutae, saline cistanche, matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, celestial being Clever spleen, thizoma curculiginis, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw jujube kernel, ripe jujube kernel, grass-leaved sweetflag, polygala, light wheat, deer horn glue, tortoise-shell glue, donkey-hide gelatin, Golden cypress, the wind-weed, charred FRUCTUS CRATAEGI, notopterygium root, levisticum, Ligusticum wallichii prescription, there is consolidating superficial resistance and supplementing qi, tonifying vital QI, Tianjing Busuiye medicinal, strengthening vital QI to eliminate pathogenic factors Effect.Supported suitable for losing inadequate natural endowment, the day after tomorrow, prolonged illness is not multiple and shows easy to catch cold, food intake reductions, loose stool abdominal distension, refreshing tired The diseases such as limb is tired, aversion to cold and cold limbs, soreness and weakness of waist and knees, impotence and premature ejaculation, infertile with, the enuresis nocturna frequency of woman.Suitable for often sick, repeatedly Breaking-out, the patient of hypoimmunity.Apply also for sub-health population, city white collar, clerk, have precancerous lesion symptom Person.Goal of the invention is reached.
The present invention is further illustrated by the following examples, but not as limitation of the present invention.
Embodiment:
Embodiment 1:
Prescription:Radix Astragali 50g, bighead atractylodes rhizome 40g, windproof 30g, suncured white ginseng root 100g, Yun Ling 50g, Chinese yam 50g, sealwort 50g, mulberries 50g, Radix Angelicae Sinensis 40g, gynostemma pentaphylla 40g, the positive 40g of southern cloth, cynanchum wilfordii 30g, fruit of glossy privet 40g, Eclipta prostrata 40g, dried rhizome of rehmannia 50g, cultivated land 50g, Semen Cuscutae 50g, saline cistanche 50g, matrimony vine 40g, RADIX POLYGONI MULTIFLORI PREPARATA 50g, HERBA EPIMEDII 40g, thizoma curculiginis 40g, fruit of Chinese magnoliavine 40g, Polygonum multiflower knotweed 30g, raw jujube kernel 30g, ripe jujube kernel 30g, grass-leaved sweetflag 30g, polygala 20g, light wheat 50g, deer horn glue 25g, tortoise-shell glue 25g, donkey-hide gelatin 25g, golden cypress 25g, wind-weed 25g, charred FRUCTUS CRATAEGI 30g, notopterygium root 15g, levisticum 15g, Ligusticum wallichii 20g, honey 100g.
Technique:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, meat desert Rong, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are quiet using steam distillation extraction 1h, collection condensate liquid Layering is put, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, 3 times are added water to cook, first 2h is boiled in secondary 8 times of amount decoctings of addition, and second of addition, 8 times of amount decoctings are boiled 1 hour, is added 6 times of amount decoctings for the third time and is boiled 0.5 hour, Collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, honey is added, agitating and heating, is concentrated into Relative density is 1.2-1.25 medicinal extract at 60-65 DEG C, adds above-mentioned volatile oil and mixes, produces soft extract.
Usage and dosage:Orally, once in the morning and once at night(Before or after meals), each 15g, it is put into hot water oral after melting; Also can directly swallow.
Embodiment 2:
Prescription:Radix Astragali 40g, bighead atractylodes rhizome 40g, windproof 30g, suncured white ginseng root 100g, Yun Ling 50g, Chinese yam 50g, sealwort 50g, mulberries 50g, Radix Angelicae Sinensis 40g, gynostemma pentaphylla 40g, the positive 40g of southern cloth, cynanchum wilfordii 30g, fruit of glossy privet 40g, Eclipta prostrata 40g, dried rhizome of rehmannia 50g, cultivated land 50g, Semen Cuscutae 60g, saline cistanche 50g, matrimony vine 40g, RADIX POLYGONI MULTIFLORI PREPARATA 50g, HERBA EPIMEDII 40g, thizoma curculiginis 40g, fruit of Chinese magnoliavine 40g, Polygonum multiflower knotweed 30g, raw jujube kernel 30g, ripe jujube kernel 30g, grass-leaved sweetflag 30g, polygala 20g, light wheat 50g, deer horn glue 25g, tortoise-shell glue 25g, donkey-hide gelatin 25g, golden cypress 25g, wind-weed 25g, charred FRUCTUS CRATAEGI 30g, notopterygium root 16g, levisticum 15g, Ligusticum wallichii 20g
Technique:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, meat desert Rong, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are quiet using steam distillation extraction 1h, collection condensate liquid Layering is put, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, 3 times are added water to cook, first 2h is boiled in secondary 8 times of amount decoctings of addition, and second of addition, 8 times of amount decoctings are boiled 1 hour, is added 6 times of amount decoctings for the third time and is boiled 0.5 hour, Collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, adds above-mentioned volatile oil and the amount of being made 10% dextrin and 0.5% magnesium stearate are well mixed, and with 65% alcohol granulation, are dried, whole grain, are loaded capsule, produce capsule Agent.
Usage and dosage:Orally, one time 3,3 times a day.
Embodiment 3:
Prescription:Radix Astragali 50g, bighead atractylodes rhizome 50g, windproof 30g, suncured white ginseng root 100g, Yun Ling 50g, Chinese yam 50g, sealwort 50g, mulberries 50g, Radix Angelicae Sinensis 40g, gynostemma pentaphylla 40g, the positive 50g of southern cloth, cynanchum wilfordii 30g, fruit of glossy privet 40g, Eclipta prostrata 40g, dried rhizome of rehmannia 50g, cultivated land 50g, Semen Cuscutae 50g, saline cistanche 50g, matrimony vine 40g, RADIX POLYGONI MULTIFLORI PREPARATA 50g, HERBA EPIMEDII 40g, thizoma curculiginis 40g, fruit of Chinese magnoliavine 40g, Polygonum multiflower knotweed 30g, raw jujube kernel 20g, ripe jujube kernel 30g, grass-leaved sweetflag 30g, polygala 20g, light wheat 50g, deer horn glue 25g, tortoise-shell glue 25g, donkey-hide gelatin 25g, golden cypress 25g, wind-weed 30g, charred FRUCTUS CRATAEGI 30g, notopterygium root 15g, levisticum 15g, Ligusticum wallichii 20g
Technique:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, meat desert Rong, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are quiet using steam distillation extraction 1h, collection condensate liquid Layering is put, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, 3 times are added water to cook, first 2h is boiled in secondary 8 times of amount decoctings of addition, and second of addition, 8 times of amount decoctings are boiled 1 hour, is added 6 times of amount decoctings for the third time and is boiled 0.5 hour, Collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, adds above-mentioned volatile oil and the amount of being made 15% dextrin and the mixing of 15% sucrose mix, and are that wetting agent makes pellet with 85% ethanol, 60 DEG C of dryings, after 12 mesh sieve 1 time, And fine powder is separated with 60 mesh sieves, produce granule.
Usage and dosage:Take after mixing it with hot water, a 10g, 3 times a day.
Embodiment 4:
Prescription:Radix Astragali 50g, bighead atractylodes rhizome 40g, windproof 30g, suncured white ginseng root 90g, Yun Ling 50g, Chinese yam 50g, sealwort 50g, mulberries 50g, Radix Angelicae Sinensis 40g, gynostemma pentaphylla 40g, the positive 40g of southern cloth, cynanchum wilfordii 30g, fruit of glossy privet 40g, Eclipta prostrata 50g, dried rhizome of rehmannia 50g, cultivated land 60g, Semen Cuscutae 50g, saline cistanche 50g, matrimony vine 40g, RADIX POLYGONI MULTIFLORI PREPARATA 50g, HERBA EPIMEDII 40g, thizoma curculiginis 40g, fruit of Chinese magnoliavine 40g, Polygonum multiflower knotweed 30g, raw jujube kernel 30g, ripe jujube kernel 30g, grass-leaved sweetflag 30g, polygala 20g, light wheat 50g, deer horn glue 25g, tortoise-shell glue 25g, donkey-hide gelatin 25g, golden cypress 25g, wind-weed 25g, charred FRUCTUS CRATAEGI 30g, notopterygium root 15g, levisticum 15g, Ligusticum wallichii 30g.
Technique:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, meat desert Rong, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are quiet using steam distillation extraction 1h, collection condensate liquid Layering is put, isolates volatile oil, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, 3 times are added water to cook, first 2h is boiled in secondary 8 times of amount decoctings of addition, and second of addition, 8 times of amount decoctings are boiled 1 hour, is added 6 times of amount decoctings for the third time and is boiled 0.5 hour, Collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, the honey of the addition amount of being made 10%, and The sodium benzoate of the amount of being made 0.2%, dissolving is boiled, add above-mentioned volatile oil and mix, add pure water to be settled to full dose, stir evenly, filter Cross, embedding, produce oral liquid.
Usage and dosage:Orally, a 15ml, 3 times a day.

Claims (10)

  1. A kind of 1. medicine for improving immunity, it is characterised in that:Calculated according to composition by weight, by Radix Astragali 20-80 parts, bighead atractylodes rhizome 20- 70 parts, windproof 10-50 parts, suncured white ginseng root 50-200 parts, Yun Ling 20-80 parts, Chinese yam 20-80 parts, sealwort 20-80 parts, mulberries 20-80 Part, Radix Angelicae Sinensis 20-70 parts, gynostemma pentaphylla 20-70 parts, the positive 20-70 parts of southern cloth, cynanchum wilfordii 10-50 parts, fruit of glossy privet 20-70 parts, Eclipta prostrata 20-70 parts, dried rhizome of rehmannia 20-80 parts, cultivated land 20-80 parts, Semen Cuscutae 20-80 parts, saline cistanche 20-80 parts, matrimony vine 20-70 parts, system are first Black 20-80 parts, HERBA EPIMEDII 20-70 parts, thizoma curculiginis 20-70 parts, fruit of Chinese magnoliavine 20-70 parts, Polygonum multiflower knotweed 10-50 parts, raw jujube kernel 10-50 Part, ripe jujube kernel 10-50 parts, grass-leaved sweetflag 10-50 parts, polygala 5-30 parts, light wheat 20-80 parts, deer horn glue 10-40 parts, tortoise-shell glue 10-40 parts, donkey-hide gelatin 10-40 parts, golden cypress 10-40 parts, wind-weed 10-40 parts, charred FRUCTUS CRATAEGI 10-50 parts, notopterygium root 5-30 parts, levisticum 5-30 Part, Ligusticum wallichii 5-30 parts and auxiliary material are prepared.
  2. 2. the medicine of immunity is improved as claimed in claim 1, it is characterised in that:Calculated according to composition by weight, by 50 parts of the Radix Astragali, 40 parts of the bighead atractylodes rhizome, windproof 30 parts, 100 parts of suncured white ginseng root, 50 parts of Yun Ling, 50 parts of Chinese yam, 50 parts of sealwort, 50 parts of mulberries, 40 parts of Radix Angelicae Sinensis, strand Stock is blue 40 parts, southern cloth is positive 40 parts, 30 parts of cynanchum wilfordii, 40 parts of the fruit of glossy privet, 40 parts of Eclipta prostrata, 50 parts of the dried rhizome of rehmannia, 50 parts of cultivated land, Semen Cuscutae 50 parts, 50 parts of saline cistanche, 40 parts of matrimony vine, 50 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 40 parts of HERBA EPIMEDII, 40 parts of thizoma curculiginis, 40 parts of the fruit of Chinese magnoliavine, Polygonum multiflower knotweed 30 Part, raw 30 parts of jujube kernel, 30 parts of ripe jujube kernel, 30 parts of grass-leaved sweetflag, 20 parts of polygala, 50 parts of light wheat, 25 parts of deer horn glue, tortoise-shell glue 25 It is prepared by part, 25 parts of donkey-hide gelatin, 25 parts of golden cypress, 25 parts of the wind-weed, 30 parts of charred FRUCTUS CRATAEGI, 15 parts of notopterygium root, 15 parts of levisticum, 20 parts of Ligusticum wallichii and auxiliary material Form.
  3. 3. prepare the method for the medicine for improving immunity of claim 1 or 2, it is characterised in that:Proportionally weigh the Radix Astragali, The bighead atractylodes rhizome, windproof, suncured white ginseng root, Yun Ling, Chinese yam, sealwort, mulberries, Radix Angelicae Sinensis, gynostemma pentaphylla, Nan Buzheng, cynanchum wilfordii, the fruit of glossy privet, Eclipta prostrata, The dried rhizome of rehmannia, cultivated land, Semen Cuscutae, saline cistanche, matrimony vine, RADIX POLYGONI MULTIFLORI PREPARATA, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, Polygonum multiflower knotweed, raw jujube kernel, ripe jujube kernel, Grass-leaved sweetflag, polygala, light wheat, deer horn glue, tortoise-shell glue, donkey-hide gelatin, golden cypress, the wind-weed, charred FRUCTUS CRATAEGI, notopterygium root, levisticum and Ligusticum wallichii and medicine Middle acceptable pharmaceutic adjuvant is combined, and is processed according to the preparation method of routine, and corresponding pharmaceutical preparation is made.
  4. 4. the preparation method of the medicine of immunity is improved as claimed in claim 3, it is characterised in that:Take the Radix Astragali, the bighead atractylodes rhizome, it is windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, Qiang Work, levisticum, Ligusticum wallichii extract 0.5-2h using steam distillation, collect condensate liquid, stratification, isolate volatile oil, standby; After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, add the 6-8 times of decocting measured and boil 2-4 times, each 0.5-2h, decoct three times Liquid filters, and merges, is condensed into medicinal extract, adds above-mentioned volatile oil, mixed with conventional pharmaceutical adjuvants, is made not according still further to conventional method Same pharmaceutical preparation.
  5. 5. the preparation method of the medicine of immunity is improved as claimed in claim 4, it is characterised in that:Take the Radix Astragali, the bighead atractylodes rhizome, it is windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, Qiang Work, levisticum, Ligusticum wallichii extract 1h using steam distillation, collect condensate liquid, stratification, isolate volatile oil, standby;Extraction After the dregs of a decoction after volatile oil mix with remaining medicinal material, add water to cook 3 times, add 8 times of amount decoctings for the first time and boil 2h, second of addition 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times of amount decoctings and boiled 0.5 hour, collecting decoction, is condensed into relatively close at 60-65 DEG C The medicinal extract for the 1.10-1.15 for being is spent, above-mentioned volatile oil is added, is mixed with conventional pharmaceutical adjuvants, is made not according still further to conventional method Same pharmaceutical preparation.
  6. 6. the preparation method of the medicine of immunity is improved as claimed in claim 3, it is characterised in that:The pharmaceutical preparation is soft extracts Agent, hard capsule, tablet, granule, pill, oral liquid, syrup, powder or sublimed preparation.
  7. 7. the preparation method of the medicine of immunity is improved as claimed in claim 6, it is characterised in that:The pharmaceutical preparation is soft extracts Agent, capsule, granule or oral liquid.
  8. 8. the preparation method of the medicine of immunity is improved as claimed in claim 7, it is characterised in that:The pharmaceutical preparation is soft extracts Agent, preparation method are as follows:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, Saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii collect condensation using steam distillation extraction 1h Liquid, stratification, volatile oil is isolated, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, add water to cook 3 times, 8 times of addition for the first time measures decoctings and boils 2h, and second of addition, 8 times of amount decoctings are boiled 1 hour, and it is small that 6 times of amount decoctings of addition for the third time boil 0.5 When, collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, the honey of the addition amount of being made 20%, Agitating and heating, relative density is 1.2-1.25 medicinal extract when being concentrated into 60-65 DEG C, adds above-mentioned volatile oil and mixes, produces.
  9. 9. the preparation method of the medicine of immunity is improved as claimed in claim 7, it is characterised in that:The pharmaceutical preparation is capsule Agent, preparation method are as follows:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Semen Cuscutae, Saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii collect condensation using steam distillation extraction 1h Liquid, stratification, volatile oil is isolated, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, add water to cook 3 times, 8 times of addition for the first time measures decoctings and boils 2h, and second of addition, 8 times of amount decoctings are boiled 1 hour, and it is small that 6 times of amount decoctings of addition for the third time boil 0.5 When, collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, add above-mentioned volatile oil and be made The dextrin and 0.5% magnesium stearate of amount 10% are well mixed, and with 65% alcohol granulation, are dried, whole grain, are loaded capsule, produce.
  10. 10. the preparation method of the medicine of immunity is improved as claimed in claim 7, it is characterised in that:The pharmaceutical preparation is Granula, preparation method are as follows:Take the Radix Astragali, the bighead atractylodes rhizome, windproof, Yun Ling, sealwort, Radix Angelicae Sinensis, gynostemma pentaphylla, cynanchum wilfordii, the fruit of glossy privet, Tu silks Son, saline cistanche, HERBA EPIMEDII, thizoma curculiginis, the fruit of Chinese magnoliavine, golden cypress, notopterygium root, levisticum, Ligusticum wallichii are collected cold using steam distillation extraction 1h Lime set, stratification, volatile oil is isolated, it is standby;After the dregs of a decoction after extraction volatile oil mix with remaining medicinal material, 3 are added water to cook It is secondary, 8 times of amount decoctings are added for the first time and boil 2h, and second of addition, 8 times of amount decoctings are boiled 1 hour, and third time adds 6 times of amount decoctings and boiled 0.5 hour, collecting decoction, the medicinal extract for the 1.10-1.15 that relative density is when being condensed into 60-65 DEG C, add above-mentioned volatile oil with It is that wetting agent makes pellet with 85% ethanol and the dextrin of the amount of being made 15% and the mixing of 15% sucrose mix, 60 DEG C of dryings, after 12 Mesh sieve 1 time, and fine powder is separated with 60 mesh sieves, produce.
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CN104687198B (en) * 2015-03-23 2016-05-18 瓜州昊泰生物科技有限公司 A kind of health beverages and preparation method with invigorating qi for tranquilization effect
CN105582168A (en) * 2016-01-08 2016-05-18 王明强 Traditional Chinese medicine preparation for treating valetudinarianism, insufficiency of primordial qi and low immunity
CN105535385A (en) * 2016-02-22 2016-05-04 广西梧州制药(集团)股份有限公司 Composition for improving resistance of organism to exogenous pathogenic factors and preparing method thereof
CN105664031A (en) * 2016-02-22 2016-06-15 广西梧州制药(集团)股份有限公司 Traditional Chinese medicine composition for enhancing cell immunity and preparation method thereof
CN105709006A (en) * 2016-02-22 2016-06-29 广西梧州制药(集团)股份有限公司 Traditional Chinese medicine composition for treating body deficient decline and preparation method thereof
CN105616880A (en) * 2016-02-22 2016-06-01 广西梧州制药(集团)股份有限公司 Traditional Chinese medicine composition with immunity enhancing function and preparation method thereof

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CN1206600A (en) * 1997-07-30 1999-02-03 黄碧有 Multi-effect nutrient health care medicinal liquor prescription for old and middle-aged people and preparation process thereof
CN101406672A (en) * 2008-11-16 2009-04-15 路敦祥 Chinese medicinal liquor for treating hypertension and preparation method thereof
CN102008391A (en) * 2010-09-26 2011-04-13 江苏省中医院 Method for solidifying traditional Chinese ointment

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CN1206600A (en) * 1997-07-30 1999-02-03 黄碧有 Multi-effect nutrient health care medicinal liquor prescription for old and middle-aged people and preparation process thereof
CN101406672A (en) * 2008-11-16 2009-04-15 路敦祥 Chinese medicinal liquor for treating hypertension and preparation method thereof
CN102008391A (en) * 2010-09-26 2011-04-13 江苏省中医院 Method for solidifying traditional Chinese ointment

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