CN105267657A - Traditional Chinese medicine preparation for treating female endocrine disorders - Google Patents
Traditional Chinese medicine preparation for treating female endocrine disorders Download PDFInfo
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- CN105267657A CN105267657A CN201510676071.8A CN201510676071A CN105267657A CN 105267657 A CN105267657 A CN 105267657A CN 201510676071 A CN201510676071 A CN 201510676071A CN 105267657 A CN105267657 A CN 105267657A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating female endocrine disorders. The traditional Chinese medicine preparation is used for treating various clinical frequently-incurring diseases due to endocrine disorders for women. The traditional Chinese medicine preparation comprises prepared radix rehmanniae, herba leonuri, folium artemisiae argyi, Szechwan chinaberry fruits, rhizoma cyperi, parched white peony roots, Chinese thorowax roots, rhizoma corydalis, angelica sinensis, achyranthes bidentata, semen cuscutae, licorice, nacre mother of pearl and polygonatum. The traditional Chinese medicine preparation has the advantages that effects of soothing livers, regulating qi, activating and replenishing blood and regulating endocrine can be realized, and as shown by clinical application, unique treatment effects can be realized by the traditional Chinese medicine preparation which is a traditional Chinese medicine composition for irregular menstruation and proliferation of mammary glands due to various endocrine disorders of pre-menopausal women, insomnia, amnesia, dysphoria, irritability, headache, dizziness and the like due to vegetative nervous disorder, chloasma and acne.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine preparation for the treatment of female endocrinic disorders and preparation method thereof, specifically, relate to insomnia forgetfulness that a kind of menoxenia, cyclomastopathy and autonomic nervous dysfunction caused the various endocrine regulations of perimenopausal cause, irritable, headache dizzy etc., all have and there is unique therapeutic effect, and Chinese medicine preparation having moistening face concurrently and preparation method thereof.
Background technology
Endocrine is one of two large control system being responsible for various physiological function normal operation in regulation and control animal body, is made up of the duct free body of gland (endocrine gland) of secreting hormone (hormone).The hormonal system of human body, secretes metabolism and physiological function that various hormone regulates human body together with nervous system.Female endocrinic disorders is that nerve because a variety of causes causes-hormone secretion regulates feedback mechanism not normal, particularly not normal the and a series of morbid states that cause of the adjustment feedback function of " hypothalamic-pituitary-ovarian axis (HPOA) ".In the modern life, because competitive pressure strengthens, tempo increase, and the change of dietary habit and living environment, endocrine regulation is one of commonly encountered diseases becoming women.The clinical manifestation of female endocrinic disorders is menoxenia, hypo-ovaria, amenorrhea, dysmenorrhea, emotional lability, soreness of the waist and knees, palpitation and insomnia, tinnitus night sweat, libido is indifferent, sterility and infertility, chaeta are abnormal.The inherence slight illness that endocrine regulation causes and the change of appearance, bring huge inconvenience and inexhaustible misery to the live and work of modern female.
Endocrine regulation can be divided into from etiology and pathogenesis: sex hormones secretion is not enough or certain single hormone secretion is too much, nervus centralis dysregulation, target organ feedback mechanism are malfunctioning or hypofunction.For the treatment of endocrine regulation, the guideline of doctor trained in Western medicine is direct endocrine regulation, makes it again to reach to balance.To the hyperfunctioning that hormone secretion too much causes, to suppress, to cut down for principle; And very few to hormone secretion, supplement its deficiency, although quick result, easily cause the long-term dependence to this kind of medicine, cure the symptoms, not the disease, and have the danger bringing out mastopathy and gynecological tumor.And from the traditional Chinese medical science, endocrine regulation is the performance of the deficiency of YIN, be retarded by silt by QI and blood caused.Congestion is detained in body, venation is obstructed, outer poison invasion human body, lochiostasis etc. all may cause that QI and blood is retarded by silt.Therefore, treat these diseases, QI and blood be made unobstructed, make essence and blood nourish whole body, blood circulation promoting, comprehensive conditioning from inside to outside, therefore Chinese medicine has original curative effect to adjustment female incretion.
People is a unified organism, and the traditional Chinese medical science thinks that the five internal organs and the five elements, the five tastes, the five colors are the relations counteracted each other.Want to balance endocrine, QI and blood first will be made unobstructed, make essence and blood nourish whole body, then nurse one's health from inside to outside comprehensively, thoroughly could balance endocrine, reach treating both the principal and secondary aspects of a disease.Human body has kidney,liver,spleen, the heart, lung the five internal organs, and what have most substantial connection with hormone secretion is liver,spleen,kidney.
Summary of the invention
The invention discloses a kind of Chinese medicine preparation for the treatment of female endocrinic disorders, said preparation takes into account treatment and conditioning, start with from adjustment liver,spleen,kidney, nutrition mediation, blood yiqi, soothing the liverization are become silted up, promote metabolism, the microcirculation of body, eliminate blockage of the vessel and make passages through which vital energy circulates unimpeded, thus endocrine regulation, eliminate the stasis of blood in body to amass, finally make the secretion level of Estrogen and progestin be tending towards equilibrium state.
The object of the invention is to be achieved through the following technical solutions:
Treat a Chinese medicine preparation for female endocrinic disorders, be made up of the raw material of following weight proportioning: Radix Rehmanniae Preparata 2-15g, Herba Leonuri 2-25g, Folium Artemisiae Argyi 2-15g, Fructus Toosendan 2-15g, Rhizoma Cyperi 2-14g, Radix Paeoniae Alba (parched) 7-20g, Radix Bupleuri 2-15g, Rhizoma Corydalis 2-15g, Radix Angelicae Sinensis 2-20g, Radix Achyranthis Bidentatae 2-20g, Semen Cuscutae 2-15g, Radix Glycyrrhizae 0-12g, Concha Margaritifera 2-25g, Rhizoma Polygonati 2-12g.
The weight proportion of described Chinese medicine preparation is preferably: Radix Rehmanniae Preparata 8-15g, Herba Leonuri 10-25g, Folium Artemisiae Argyi 8-15g, Fructus Toosendan 5-10g, Rhizoma Cyperi 6-14g, Radix Paeoniae Alba (parched) 10-20g, Radix Bupleuri 5-15g, Rhizoma Corydalis 5-15g, Radix Angelicae Sinensis 6-15g, Radix Achyranthis Bidentatae 10-20g, Semen Cuscutae 8-15g, Radix Glycyrrhizae 6-12g, Concha Margaritifera 15-25g, Rhizoma Polygonati 6-12g.
The further preferred weight proportioning of described Chinese medicine preparation is: Radix Rehmanniae Preparata 10g, Herba Leonuri 20g, Folium Artemisiae Argyi 10g, Fructus Toosendan 10g, Rhizoma Cyperi 10g, Radix Paeoniae Alba (parched) 15g, Radix Bupleuri 10g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 15g, Semen Cuscutae 10g, Radix Glycyrrhizae 10g, Concha Margaritifera 20g, Rhizoma Polygonati 10g.
Further, described medicine is peroral dosage form.
Further, described peroral dosage form is decoction, powder, tablet, pill or capsule.
Further, described decoction adopts decocting method to make.
The raw material of Chinese medicine proportioning of the preparation for the treatment of female endocrinic disorders of the present invention and other number are all with parts by weight.The Chinese medicine preparation of this treatment women's endocrine disorder can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional mouth dosage form, such as, menstruation-regulating face-beautifying Chinese medicine preparation decocting cooking method of the present invention obtains active component extract, makes various medicinal preparation for oral administration as decoction, tablet, capsule, pill, powder etc. with 1-100 part active component and 99-0 part pharmaceutic adjuvant.
The property of medicine of crude drug that the present invention adopts, pharmacology and effect are as follows:
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.To enrich blood yin nourishing, life essence-filling, marrow-benefitting.For blood deficiency and yellow complexion, dizzy, cardiopalmus, insomnia and menoxenia, metrorrhagia and metrostaxis etc.
Herba Leonuri: bitter in the mouth, pungent, cold nature.Promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
Folium Artemisiae Argyi: toil, warm in nature.Dispersing cold for relieving pain, warming the meridian for stopping bleeding.For few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile, spit blood, epistaxis, metrorrhagia through many, gestation hemorrhage; External treatment skin pruritus, decortication.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding.Hemorrhage for deficient cold type.
Fructus Toosendan: bitter in the mouth, cold in nature.Soothing the liverly to expel the heat-evil, promoting the circulation of QI to relieve pain, parasite killing.For pathogenic fire derived from stagnation of liver-QI, the breast side of body, abdominal distention, hernia pain, abdominal pain due to worm stagnation.
Rhizoma Cyperi: acrid in the mouth, micro-hardship, micro-sweet, property is put down.Dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menoxenia, amenorrhea dysmenorrhea.
Radix Paeoniae Alba (parched): bitter in the mouth, acid, to be slightly cold, cool in nature.Blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating.For fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.
Radix Bupleuri: bitter in the mouth, cold nature.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.Promoting blood circulation to remove blood stasis, regulating QI to relieve pain.For whole body each portion qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.For all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down.
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down.Invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.For soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil; Laryngopharynx swelling and pain.
Semen Cuscutae: acrid in the mouth, sweet, property is put down.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.Waist knee joint muscles and bones for deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Radix Glycyrrhizae: sweet in the mouth, property is put down.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Concha Margaritifera: sweet in the mouth, salty, cold in nature.Suppressing the hyperactive liver and subsiding YANG; To calm the nerves arresting convulsion; Liver heat removing and eyesight improving.For dizziness, tinnitus, cardiopalmus, insomnia, demented, infantile convulsion, spits blood, epistaxis, metrorrhagia.
Rhizoma Polygonati: sweet in the mouth; Property is put down, spleen; Lung; Kidney channel, boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For deficiency of YIN chronic cough; Xeropulmonary cough; Insufficiency of the spleen weak; Lack of appetite xerostomia; Quench one's thirst; Deficiency of the kidney soreness of the waist and knees; Impotence and seminal emission; Tinnitus order is dark; Early whitening of beard and hair; Body void is won thin; Wind favus disease.
Find in clinical practice, medicine of the present invention has depressed liver-energy dispersing and QI regulating, blood circulation promoting and enriching, effect of endocrine regulation, the insomnia forgetfulness that the menoxenia caused for the various endocrine regulations of perimenopausal, cyclomastopathy and autonomic nervous dysfunction cause, irritable, headache are dizzy, chloasma, and acne all has and has unique therapeutic effect, conditions of patients alleviates or cures completely, and complexion blush, appearance are shone.Patient treatment add up: amount to 2114 example, minimum 17 years old of age, the maximum 54 years old, the state of an illness cure completely 1824 example, reach 86.3%, the state of an illness be clearly better 213 example, account for 10.1%, invalid 77 example, account for 3.6%, the effective percentage of Chinese medicine preparation of the present invention reaches 96.4% altogether.
Compared with prior art, Chinese medicine preparation of the present invention has following characteristics and advantage:
1. adopt natural pure Chinese medicinal preparation, do not use hormone, have no side effect, and with low cost, and curative effect is fast.
2. base oneself upon traditional Chinese medical science global theory, treating both the principal and secondary aspects of a disease, control and support combination; Nutrition mediation, blood yiqi, soothing the liverization are become silted up, and promote metabolism, the microcirculation of body, eliminate blockage of the vessel and make passages through which vital energy circulates unimpeded.
3. the present invention is in the application of Qingdao Jun Ping combination of Chinese and Western medicine out-patient department, and the continuous summary in clinical practice is perfect, has unique therapeutic effect, successfully cure thousands of routine patient to the women's endocrine disorder that a variety of causes causes.
Detailed description of the invention:
Below in conjunction with embodiment, the present invention is further illustrated, below Chinese medicine preparation of the present invention is called No. I, endocrine:
Embodiment 1
Get Radix Rehmanniae Preparata 10g, Herba Leonuri 20g, Folium Artemisiae Argyi 10g, Fructus Toosendan 10g, Rhizoma Cyperi 10g, Radix Paeoniae Alba (parched) 15g, Radix Bupleuri 10g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 15g, Semen Cuscutae 10g, Radix Glycyrrhizae 10g, Concha Margaritifera 20g, Rhizoma Polygonati 10g, mixes the raw material of Chinese medicine of above-mentioned weight proportion, puts into container, and add 1.8kg water, slow fire boiling 60 minutes, medicine decoction of the present invention can be obtained.
Embodiment 2
Get Radix Rehmanniae Preparata 10g, Herba Leonuri 15g, Folium Artemisiae Argyi 8g, Fructus Toosendan 9g, Rhizoma Cyperi 7g, Radix Paeoniae Alba (parched) 12g, Radix Bupleuri 8g, Rhizoma Corydalis 7g, Radix Angelicae Sinensis 10g, Radix Achyranthis Bidentatae 10g, Semen Cuscutae 8g, Radix Glycyrrhizae 7g, Concha Margaritifera 15g, Rhizoma Polygonati 8g, mixes the raw material of Chinese medicine of above-mentioned weight proportion, puts into container, add 1.5kg water, slow fire boiling 60 minutes, get its decocting liquid.Such soak by water twice, collecting decoction, filters, and filtrate is concentrated, dry, adds 50g supplementary product starch, granulates, tabletting, i.e. obtained tablet of the present invention.
Embodiment 3
Get Radix Rehmanniae Preparata 10g, Herba Leonuri 12g, Folium Artemisiae Argyi 6g, Fructus Toosendan 7g, Rhizoma Cyperi 6g, Radix Paeoniae Alba (parched) 8g, Radix Bupleuri 6g, Rhizoma Corydalis 5g, Radix Angelicae Sinensis 7g, Radix Achyranthis Bidentatae 6g, Semen Cuscutae 5g, Radix Glycyrrhizae 5g, Concha Margaritifera 10g, Rhizoma Polygonati 6g, mixes the raw material of Chinese medicine of above-mentioned weight proportion, puts into container, add 1.9kg water, slow fire boiling 60 minutes, get its decocting liquid.Such soak by water twice, merging filtrate, makes capsule preparations by the conventional method of Chinese medicine preparation.
Embodiment 4
Get Radix Rehmanniae Preparata 10g, Herba Leonuri 14g, Folium Artemisiae Argyi 7g, Fructus Toosendan 8g, Rhizoma Cyperi 7g, Radix Paeoniae Alba (parched) 9g, Radix Bupleuri 8g, Rhizoma Corydalis 7g, Radix Angelicae Sinensis 8g, Radix Achyranthis Bidentatae 7g, Semen Cuscutae 6g, Radix Glycyrrhizae 7g, Concha Margaritifera 12g, Rhizoma Polygonati 8g, mix the raw material of Chinese medicine of above-mentioned weight proportion, add 1.7kg water, slow fire boiling 60 minutes, get its decocting liquid.Such soak by water twice, merging filtrate, makes powder or pill by the conventional method of Chinese medicine preparation.
Drug administration method of the present invention: the decocting decoction once in about 300ml above-described embodiment 1, point morning and evening is each once, daily potion.Within 7 days, be a course for the treatment of, take 1-2 the course for the treatment of continuously.As made pill, powder or capsule, can take with reference to " daily potion, twice on the one ".
Model case is illustrated:
Case 1
Korea Spro so-and-so, female, 38 years old
Breast outer upside pain, monthly premenstrual pain aggravation, after passing through, pain goes down or disappears, sometimes pain is radiated to armpit, and bitter taste rib is swollen, uncomfortable in chest, anorexia, menoxenia, is diagnosed as cyclomastopathy, give embodiment 1 prepare endocrine I plus-minus take 10 doses after, pain relief is obvious, and after further consultation continues to take 10 doses, symptom disappears substantially, the eumenorrhea.After March, outpatient service is with examining, and symptom is almost recovered.
Case 2
Pueraria lobota, female, 48 years old
Menoxenia, 2-3 month a line, color secretly has clot, companion's irritable, and complexion is dim, weak fatigue, red tongue with thin and yellow fur, deep and stringy pulse, is diagnosed as menoxenia, give embodiment 2 prepare endocrine No. I 20 doses after menstrual onset, rear interruption takes 20 doses, and menstrual cycle recovers normal, and color is red, without clot.Follow-up after 1 year, menstruation is normal.
Case 3
Zhao, female, 44 years old
Insomnia, irritated, xerostomia, thirsty, weak, blood glucose is unstable, night red heat, perspire in front, uncomfortable in chest, sighing frequently, time had palpitation.Be diagnosed as autonomic nervous dysfunction, No. I, endocrine plus-minus 7 pairs of symptoms of giving embodiment 3 preparation significantly alleviate, and after further consultation 21 doses, symptom disappears substantially.Follow-up after 1 year, symptom is almost recovered.
Case 4
Wang, female, 28 years old
Suffered from facial acne before 1 year, attach most importance to cervical region and lower jaw, with irritable, menoxenia, bitter taste xerostomia.Be diagnosed as acne, after giving No. 1, the endocrine plus-minus 10 doses of embodiment 3 preparation, acne flattens, and color is light than before, and after further consultation continues to take 20 doses, acne disappears substantially, the eumenorrhea.Follow-up after March, acne does not recur.
Case 5
Cui, female, 43 years old
Face in flakes chloasma, companion's menstruation has clot, lumbago, time have mastalgia, appetite is normal, sleep can, light red tongue, white and thin fur, stringy pulse.Be diagnosed as chloasma, giving No. 1, endocrine prepared by embodiment 4, to take 10 doses of patches obviously thin out, and after 20 doses, disappear in the large portion of chloasma, and the colour of skin bleaches.Following the service 10 doses is thoroughly consolidated.Follow-up after 1 year, symptom disappears substantially.
Case 6
Honest and just certain, female, 31 years old
Menstruation delays 2 wheat harvesting periods not extremely, Hypomenorrhea, dysmenorrhea, yellowish complexion, and lack of appetite is weak, companion's lumbago, sighing frequently, forgetful insomnia, chloasma faciei.Be diagnosed as: menoxenia companion chloasma, endocrine No. 1 plus-minus giving embodiment 4 preparation takes 10 doses, menstrual onset, and normal through measuring, color is red, and dysmenorrhea alleviates, and chloasma is thin out, and further consultation following the service 10 doses, symptom disappears substantially.After March, outpatient service is with examining, and menstruation is normal.
Claims (6)
1. treat a Chinese medicine preparation for female endocrinic disorders, it is characterized in that, be made up of the raw material of following weight proportioning: Radix Rehmanniae Preparata 2-15g, Herba Leonuri 2-25g, Folium Artemisiae Argyi 2-15g, Fructus Toosendan 2-15g, Rhizoma Cyperi 2-14g, Radix Paeoniae Alba (parched) 7-20g, Radix Bupleuri 2-15g, Rhizoma Corydalis 2-15g, Radix Angelicae Sinensis 2-20g, Radix Achyranthis Bidentatae 2-20g, Semen Cuscutae 2-15g, Radix Glycyrrhizae 0-12g, Concha Margaritifera 2-25g, Rhizoma Polygonati 2-12g.
2. the Chinese medicine preparation for the treatment of female endocrinic disorders as claimed in claim 1, is characterized in that, be made up of the raw material of following weight proportioning: Radix Rehmanniae Preparata 8-15g, Herba Leonuri 10-25g, Folium Artemisiae Argyi 8-15g, Fructus Toosendan 5-10g, Rhizoma Cyperi 6-14g, Radix Paeoniae Alba (parched) 10-20g, Radix Bupleuri 5-15g, Rhizoma Corydalis 5-15g, Radix Angelicae Sinensis 6-15g, Radix Achyranthis Bidentatae 10-20g, Semen Cuscutae 8-15g, Radix Glycyrrhizae 6-12g, Concha Margaritifera 15-25g, Rhizoma Polygonati 6-12g.
3. the Chinese medicine preparation for the treatment of female endocrinic disorders as claimed in claim 2, is characterized in that, be made up of the raw material of following weight proportioning: Radix Rehmanniae Preparata 10g, Herba Leonuri 20g, Folium Artemisiae Argyi 10g, Fructus Toosendan 10g, Rhizoma Cyperi 10g, Radix Paeoniae Alba (parched) 15g, Radix Bupleuri 10g, Rhizoma Corydalis 10g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 15g, Semen Cuscutae 10g, Radix Glycyrrhizae 10g, Concha Margaritifera 20g, Rhizoma Polygonati 10g.
4. the Chinese medicine preparation of the treatment female endocrinic disorders according to any one of claim 1-3, is characterized in that, described medicine is peroral dosage form.
5. the Chinese medicine preparation for the treatment of female endocrinic disorders as claimed in claim 4, it is characterized in that, described peroral dosage form is decoction, powder, tablet, pill or capsule.
6. the Chinese medicine preparation for the treatment of female endocrinic disorders as claimed in claim 5, is characterized in that, described decoction adopts decocting method to make.
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| WO2021057089A1 (en) * | 2019-09-24 | 2021-04-01 | 江苏康仁医药科技开发有限公司 | Composition with chloasma removal function, preparation method therefor and use thereof |
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Application publication date: 20160127 |
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