CN105617286A - Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions - Google Patents

Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions Download PDF

Info

Publication number
CN105617286A
CN105617286A CN201610147657.XA CN201610147657A CN105617286A CN 105617286 A CN105617286 A CN 105617286A CN 201610147657 A CN201610147657 A CN 201610147657A CN 105617286 A CN105617286 A CN 105617286A
Authority
CN
China
Prior art keywords
parts
pharmaceutical composition
tarragon
blood stasis
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610147657.XA
Other languages
Chinese (zh)
Inventor
刘学键
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yantai Huawen Xinxin Pharmaceutical Co Ltd
Original Assignee
Yantai Huawen Xinxin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yantai Huawen Xinxin Pharmaceutical Co Ltd filed Critical Yantai Huawen Xinxin Pharmaceutical Co Ltd
Priority to CN201610147657.XA priority Critical patent/CN105617286A/en
Priority to CN201610193551.3A priority patent/CN105617290A/en
Publication of CN105617286A publication Critical patent/CN105617286A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/32—Manganese; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/902—Sparganiaceae (Bur-reed family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Inorganic Chemistry (AREA)

Abstract

The invention discloses a medicine composition which contains Chinese mugwort leaves and has the blood circulation promoting and blood stasis removing functions and belongs to the technical field of traditional Chinese medicine. The medicine composition is prepared from Chinese mugwort leaves, radix saliva, radix angelica sinensis, red peony roots, ligusticum wallichii, rhizoma corydalis, radix curcumae, rhizoma curcumae longae, mastix, myrrh, faeces trogopterori, rhizoma curcumae, rhizoma sparganii, cattail pollen and licorice roots. The medicine composition has the effects of warming and activating meridians, dispelling cold, removing blood stasis, removing pain, eliminating stasis, regulating menstruation and relieving pain in the aspects of promoting blood circulation and removing blood stasis, and the medicine composition further has the advantages of being simple in preparation technology, good in curative effect, low in side effect, convenient to take, easy to apply and popularize and the like.

Description

A kind of pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon
Technical field
The invention belongs to technical field of traditional Chinese medicines, it relates to a kind of pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon.
Background technology
Promoting blood circulation and removing blood stasis refer to by the method that there is dissipation role maybe can attack the pharmacological agent hemostasis disease by hemostasis in body. The visceral dysfunction that various different reason causes or because external force makes local blood vessels obstructed, all can cause hematogenous blockage in a certain position of human body or tissue, thus cause pain even to form the structural changes such as swollen block.
Chinese medicine is promoting blood circulation and removing blood stasis is a kind of comprehensively regulating effect, adjustable function, dredging blood vessel, and eliminate pain makes diseased region recover normal. Promoting blood circulation and removing blood stasis have that unobstructed blood vessels, the dissipation stasis of blood are stagnant, the effect of menstruction regulating and pain relieving, applied widely, if stasis blocking is in uncomfortable in chest pained, the cyanotic lips caused by the heart; Stasis blocking is in the pectoralgia hemoptysis caused by lung; Stasis blocking is in the hypochondriac pain lump in the abdomen caused by liver; Stasis blocking is ached in the underbelly caused by uterus, menoxenia, dysmenorrhoea etc.; Stasis blocking is livid purple in the partial gall caused by limbs; Stasis blocking is in the hemiplegia etc. caused by train of thought. The medicine composition prescriptions such as conventional Ligusticum wallichii, peach kernel, safflower, the radix paeoniae rubrathe, the red sage root, cattail pollen, frankincense, myrrh, represent prescription and have peach kernel CHENGQI TANG, decoction for removing blood stasis, post-equalization blood activating decoction and decoction for warming channels etc., normal same tonifying Qi promoting blood circulation and removing blood stasis, nourish blood, warming channel and expelling cold, heat-clearing, promoting the circulation of qi and capture etc. therapy with the use of.
Chinese patent application 200910145012.2 discloses a kind of Chinese medicine promoting blood circulation and removing blood stasis, and this Chinese medicine is made up of following raw material: Radix Astragali 25-35g; Radix Angelicae Sinensis 25-35g; Tree Peony Bark 25-35g; Cassia twig 25-35g; Radix paeoniae rubrathe 25-35g; White tuckahoe 25-35g; Rhizoma Sparganii 25-35g; Curcuma zedoary 25-35g; Raw peach kernel 25-35g; Safflower 25-35g; Unprocessed leech 45-55g and Concha Ostreae 45-55g. This Chinese medicine has function promoting blood circulation and removing blood stasis, promoting QI to circulate and dispersing the agglomeration of the pathogens, evident in efficacy in treatment hysteromyoma and ovarian cysts, but the action period is long, cures the symptoms, not the disease, and can not alleviate patient painful in the short period of time.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon, this pharmaceutical composition is in promoting blood circulation and removing blood stasis, pointed advantage strong, rapid-action, evident in efficacy, meanwhile, the present invention also provides the preparation method of a kind of described pharmaceutical composition.
The pharmaceutical composition that the present invention has function promoting blood circulation and removing blood stasis is prepared from by the raw material of following weight part: tarragon 5-25 part, red sage root 9-15 part, Radix Angelicae Sinensis 6-15 part, radix paeoniae rubrathe 6-12 part, Ligusticum wallichii 6-12 part, Yanhusuo 3-9 part, root tuber of aromatic turmeric 3-9 part, turmeric 3-9 part, frankincense 3-9 part, myrrh 3-9 part, Trogopterus Dung 6-12 part, curcuma zedoary 6-12 part, Rhizoma Sparganii 3-9 part, cattail pollen 3-9 part and Radix Glycyrrhizae 1-10 part.
Further, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
Further, pharmaceutical composition of the present invention is prepared from by the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
Correspondingly, the present invention also provides the preparation method of described pharmaceutical composition, comprises following processing step: takes above-mentioned Chinese medicinal materials and is broken into meal, the ethanolic soln that volumetric concentration is 40%-95% is doubly added according to the 4-9 of meal gross weight, refluxing extraction 2-3 time, return time is 2-5h, filters, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80-100 order sieve, obtain pharmaceutical composition of the present invention.
Further, in Chinese medicine material medicine fine powder, add suitable auxiliary material, make clinical required formulation with modern Chinese herbal medicine preparation common process, such as capsule, tablet, powder, granule, oral liquid or pill.
Source, the nature and flavor of each component of pharmaceutical composition of the present invention, return through and effect:
Tarragon: this product is the dry leave of feverfew Chinese mugwort; Taste is pungent, bitter, warm in nature; Return liver, spleen, kidney channel; Dispersing cold for relieving pain, warming the meridian for stopping bleeding.
The red sage root: this product is the dry root and rhizome of the labiate red sage root; Bitter, cold nature; The thoughts of returning home, Liver Channel; Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.
Radix Angelicae Sinensis: this product is the dry root of umbelliferae angelica; Taste is sweet, pungent, warm in nature; Return liver, the heart, the spleen channel; Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, relax bowel.
The radix paeoniae rubrathe: this product is ranunculaceae plant Chinese herbaceous peony or the dry root of the river radix paeoniae rubrathe; Bitter, cold nature; Return Liver Channel; Clearing heat and cooling blood, blood stasis removing analgesic.
Ligusticum wallichii: this product is the dry rhizome of samphire Ligusticum wallichii; Taste is pungent, warm in nature; Return liver, courage, pericardium warp; Blood-activating and qi-promoting, wind-expelling pain-stopping.
Yanhusuo: this product is the dry tuber of papaveraceae plant corydalis; Taste is pungent, bitter, warm in nature; Return liver, the spleen channel; Invigorate blood circulation, profit gas, pain relieving.
Root tuber of aromatic turmeric: this product is the dried root of zingiberaceous plant RADIX CURCUMAE, turmeric, Guangxi zedoary or zddoary; Taste is pungent, bitter, cold in nature; Return liver, the heart, lung channel; Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.
Turmeric: this product is the dry rhizome of zingiberaceous plant turmeric; Taste is pungent, bitter, warm in nature; Return spleen, Liver Channel; Broken blood gas, inducing meastruation to relieve menalgia.
Frankincense: this product is Bursera family Boswellia carterii platymiscium Boswellia carterii, medicine glue Xiang Shu and wild Boswellia carterii etc., is used as medicine with the oleo-gum-resin that its trunk skin zone wound oozes out; Taste is pungent, bitter, warm in nature; Promoting blood circulation and stopping pain.
Myrrh: Bursera family bdellium plant myrrh and belong to the oleo-gum-resin that the trunk skin zone of his kind of plant oozes out together; Bitter, property is put down; Blood stasis removing analgesic, externally used detumescence myogenic.
Trogopterus Dung: this product is flying squirrel section animal orange foot flying squirrel or the dry ight soil flying the little flying squirrel of murine; Taste is sweet, warm in nature; Promoting blood circulation to remove blood stasis, fries charcoal hemostasis.
Curcuma zedoary: this product is the dry rhizome of zingiberaceous plant zddoary, Guangxi zedoary or RADIX CURCUMAE; Taste is pungent, bitter, warm in nature; Return liver, the spleen channel; Blood is broken in promoting the circulation of qi, and disappear long-pending pain relieving.
Rhizoma Sparganii: this product is the dry tuber of the black Rhizoma Sparganii of Sparganiaceae plant; Taste is pungent, bitter, and property is put down; Return liver, the spleen channel; Broken blood gas, disappear long-pending pain relieving.
Cattail pollen: this product is the dry pollen of the cattail section turbid cattail of vegetation water, east cattail or congener; Taste is sweet, and property is put down; Return liver, pericardium warp; Hemostasis, stagnation resolvation, treating stranguria.
Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, glycyrrhiza inflate bat or glycyrrhiza glabra; Taste is sweet, and property is put down; The thoughts of returning home, lung, spleen, stomach warp; Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The compatibility analysis of pharmaceutical composition prescription of the present invention:
Pharmaceutical composition prescription of the present invention to dialectical cognition promoting blood circulation and removing blood stasis according to the traditional Chinese medical science, is followed the compatibility theory of Chinese medicine, in order to make the preparation facilitating easy-to-use and stable curative effect, is enhanced the usage quantity of medicinal material. This prescription is with tarragon, the red sage root and ought be classified as monarch's medicine, stasis-dispelling and pain-killing, promoting blood circulation and removing blood stasis; Taking curcuma zedoary, Yanhusuo, root tuber of aromatic turmeric, the radix paeoniae rubrathe and turmeric as ministerial drug, promoting blood circulation and stopping pain, blood stasis removing analgesic and detumescence myogenic; Taking Rhizoma Sparganii, frankincense, Ligusticum wallichii, Trogopterus Dung and myrrh as adjutant, regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, the broken blood of promoting the circulation of qi and the long-pending pain relieving that disappears; Taking cattail pollen and Radix Glycyrrhizae as making medicine, the coordinating the actions of various ingredients in a prescription property of medicine, all medicines coordinate, and complement each other, and synergy, has very significant curative effect in promoting blood circulation and removing blood stasis.
Compared with prior art, the present invention has following technical superiority:
1. pharmaceutical composition of the present invention has stasis-dispelling and pain-killing, promoting blood circulation and removing blood stasis and detumescence effect such as myogenic, also has that preparation technology is simple, good effect, side effect are low, easy administration and be easy to advantages such as applying;
2. compared with chemotherapeutic agent currently promoting blood circulation and removing blood stasis, pharmaceutical composition thing of the present invention is that natural pure Chinese medicinal preparation, untoward reaction and side effect significantly reduce, and pharmaceutical composition thing effect of the present invention is comprehensive, and medication effect is better;
3. pharmaceutical composition of the present invention is in the clinical experiment for the treatment of qi stagnation and blood stasis type chloasma, the efficiency that always has for the treatment of qi stagnation and blood stasis type chloasma is 96.67%, what be significantly higher than conventional medicine toxin-discharging nourishing capsule always has efficiency 66.67%, therefore medicine composite for curing qi stagnation and blood stasis type chloasma effect of the present invention is remarkable, can be used as drug use promoting blood circulation and removing blood stasis, clinical generalization value height.
Therefore, the present invention also claimed aforementioned pharmaceutical compositions in the application prepared in activating blood and removing stasis drug.
Embodiment
The present invention is further described below by way of specific embodiment, the present invention is not limited only to following examples, within the scope of the invention or not departing from the content of the present invention, spirit and scope, change, combination or the replacement that the present invention is carried out, it is apparent for a person skilled in the art, and it is included within the scope of the present invention.
Embodiment 1
Embodiment 1 pharmaceutical composition is made up of the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
Preparation method is as follows: gets the above-mentioned Chinese medicinal materials of recipe quantity and is broken into meal, add, according to 4 times of meal gross weight, the ethanolic soln that volumetric concentration is 50%, refluxing extraction 3 times, return time is 3h, filter, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80 order sieves, obtain pharmaceutical composition of the present invention, Chinese medicine material medicine fine powder adds suitable capsule auxiliary material, makes capsule with modern Chinese herbal medicine preparation common process.
Embodiment 2
Embodiment 2 pharmaceutical composition is made up of the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
Preparation method is as follows: gets the above-mentioned Chinese medicinal materials of recipe quantity and is broken into meal, add, according to 5 times of meal gross weight, the ethanolic soln that volumetric concentration is 70%, refluxing extraction 3 times, return time is 3h, filter, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80 order sieves, obtain pharmaceutical composition of the present invention, Chinese medicine material medicine fine powder adds suitable capsule auxiliary material, makes capsule with modern Chinese herbal medicine preparation common process.
Embodiment 3
Embodiment 3 pharmaceutical composition is made up of the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 2.
Embodiment 4
Embodiment 4 pharmaceutical composition is made up of the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
Preparation method is with embodiment 2.
The clinical efficacy of medicine composite for curing qi stagnation and blood stasis type chloasma of the present invention
1, case data: all experimenters are the qi stagnation and blood stasis type clinical volunteer patient of chloasma women, totally 270 example, it is divided into test 1 group at random, tests 2 group and control group, often organize each 90 examples, test patient age 23-48 year in 1 group, year mean age (28.3 �� 4.1), the course of disease 8 months-9 years, average course of disease (3.7 �� 2.7) year; Test patient age 25-45 year in 2 groups, year mean age (27.5 �� 3.8), the course of disease 7 months-10 years, average course of disease (3.5 �� 3.0) year; Patient age 21-46 year in control group, year mean age (29.1 �� 4.4), the course of disease 10 months-9 years, average course of disease (3.5 �� 2.8) year. Through confirm, participate in this research all patients all meet Case definition and with following symptom: there is tawny patch in face, soreness of the waist and knees, or being irritable and getting angry easily, distending pain in the chest and hypochondrium; Dark tongue quality, white and thin fur, deep-thready pulse. Experimenter all makes a definite diagnosis as patient with chloasma, and get rid of other serious change and medicine contraindication patient, meet the primary condition of this research, the physical data no significant differences such as age of three groups of patients, the course of disease, P > 0.05, difference does not have statistical significance, can carry out good comparison and analysis between group.
2, test method:
Control group: oral toxin-discharging nourishing capsule (the accurate word Z53020685 of traditional Chinese medicines, Yunnan interwined dragon sea of clouds pharmaceutcal corporation, Ltd), one time 2, every day 2 times;
Test 1 group: the obtained capsule of the oral embodiment of the present invention 3, every day 2 times, each 3;
Test 2 groups: the obtained capsule of the oral embodiment of the present invention 4, every day 2 times, each 3;
Three groups, all taking 4 weeks as a course for the treatment of, judge curative effect after treating 1 course for the treatment of, and between medication period, many drinking waters fruit, vegetables, drink boiled water more, and fasting or few edible oil explode, pungent irritating food.
3, criterion of therapeutical effect:
The chloasma criterion of therapeutical effect of revision in 2003 is organized with reference to the Dermatology specialty council of combination of Chinese tradiational and Western medicine association of China pigment disease.
Cure: naked eyes disappear depending on color spot area and are greater than 90%, and color disappears substantially;
Effective: meat is greater than 60% with disappearing depending on color spot area, and color obviously becomes light;
Effective: naked eyes disappear depending on color spot area be greater than 30%. colors become light;
Invalid: naked eyes disappear depending on color spot area and are less than 30%, color change is not obvious.
Always there is efficiency=(healing+effective+effective)/total number of cases �� 100%
4, clinical test results is in table 1:
Table 1 takes Chinese medicine composition of the present invention and the observation of curative effect taking routine medication chloasma
The treatment test 1 group, testing 2 group always has efficiency to be respectively 96.7% and 95.6%, obviously always there is efficiency higher than control group, and test 1 group, test 2 and group untoward reaction does not all occur, show to use medicine composite for curing qi stagnation and blood stasis type chloasma curative effect of the present invention definite, safe and reliable, can be used as the effective ways for the treatment of qi stagnation and blood stasis type chloasma.

Claims (7)

1. one kind contains the pharmaceutical composition with function promoting blood circulation and removing blood stasis of tarragon, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5-25 part, red sage root 9-15 part, Radix Angelicae Sinensis 6-15 part, radix paeoniae rubrathe 6-12 part, Ligusticum wallichii 6-12 part, Yanhusuo 3-9 part, root tuber of aromatic turmeric 3-9 part, turmeric 3-9 part, frankincense 3-9 part, myrrh 3-9 part, Trogopterus Dung 6-12 part, curcuma zedoary 6-12 part, Rhizoma Sparganii 3-9 part, cattail pollen 3-9 part and Radix Glycyrrhizae 1-10 part.
2. the pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon as claimed in claim 1, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 5 parts, the red sage root 9 parts, Radix Angelicae Sinensis 6 parts, the radix paeoniae rubrathe 6 parts, Ligusticum wallichii 6 parts, Yanhusuo 3 parts, root tuber of aromatic turmeric 3 parts, 3 parts, turmeric, frankincense 3 parts, myrrh 3 parts, Trogopterus Dung 6 parts, curcuma zedoary 6 parts, Rhizoma Sparganii 3 parts, cattail pollen 3 parts and 1 part, Radix Glycyrrhizae.
3. the pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon as claimed in claim 1, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 25 parts, the red sage root 15 parts, Radix Angelicae Sinensis 15 parts, the radix paeoniae rubrathe 12 parts, Ligusticum wallichii 12 parts, Yanhusuo 9 parts, root tuber of aromatic turmeric 9 parts, 9 parts, turmeric, frankincense 9 parts, myrrh 9 parts, Trogopterus Dung 12 parts, curcuma zedoary 12 parts, Rhizoma Sparganii 9 parts, cattail pollen 9 parts and 10 parts, Radix Glycyrrhizae.
4. the pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon as claimed in claim 1, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 10 parts, the red sage root 12 parts, Radix Angelicae Sinensis 13 parts, the radix paeoniae rubrathe 10 parts, Ligusticum wallichii 8 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 5 parts, myrrh 5 parts, Trogopterus Dung 8 parts, curcuma zedoary 7 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 8 parts, Radix Glycyrrhizae.
5. the pharmaceutical composition with function promoting blood circulation and removing blood stasis containing tarragon as claimed in claim 1, it is characterized in that, described pharmaceutical composition is prepared from by the raw material of following weight part: tarragon 15 parts, the red sage root 12 parts, Radix Angelicae Sinensis 10 parts, the radix paeoniae rubrathe 9 parts, Ligusticum wallichii 9 parts, Yanhusuo 6 parts, root tuber of aromatic turmeric 6 parts, 6 parts, turmeric, frankincense 6 parts, myrrh 6 parts, Trogopterus Dung 9 parts, curcuma zedoary 9 parts, Rhizoma Sparganii 6 parts, cattail pollen 6 parts and 5 parts, Radix Glycyrrhizae.
6. as described in item as arbitrary in claim 1-5 containing the pharmaceutical composition with function promoting blood circulation and removing blood stasis of tarragon, it is characterised in that: described pharmaceutical composition is made into capsule, tablet, powder, granule, oral liquid or pill.
7. as described in item as arbitrary in claim 1-5 containing the pharmaceutical composition with function promoting blood circulation and removing blood stasis of tarragon, it is characterised in that, the preparation method of described pharmaceutical composition comprises the following steps: takes recipe quantity traditional Chinese medicinal material raw materials and is broken into meal, the ethanolic soln that volumetric concentration is 40%-95% is doubly added according to the 4-9 of meal gross weight, refluxing extraction 2-3 time, return time is 2-5h, filters, merging filtrate, filtrate recycling ethanol, dry, pulverize into fine powder, cross 80-100 order sieve, obtain pharmaceutical composition.
CN201610147657.XA 2016-03-16 2016-03-16 Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions Withdrawn CN105617286A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201610147657.XA CN105617286A (en) 2016-03-16 2016-03-16 Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions
CN201610193551.3A CN105617290A (en) 2016-03-16 2016-03-16 Application of medicinal composition in preparing medicine for promoting circulation and removing stasis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610147657.XA CN105617286A (en) 2016-03-16 2016-03-16 Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610193551.3A Division CN105617290A (en) 2016-03-16 2016-03-16 Application of medicinal composition in preparing medicine for promoting circulation and removing stasis

Publications (1)

Publication Number Publication Date
CN105617286A true CN105617286A (en) 2016-06-01

Family

ID=56032890

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201610193551.3A Withdrawn CN105617290A (en) 2016-03-16 2016-03-16 Application of medicinal composition in preparing medicine for promoting circulation and removing stasis
CN201610147657.XA Withdrawn CN105617286A (en) 2016-03-16 2016-03-16 Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201610193551.3A Withdrawn CN105617290A (en) 2016-03-16 2016-03-16 Application of medicinal composition in preparing medicine for promoting circulation and removing stasis

Country Status (1)

Country Link
CN (2) CN105617290A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620533A (en) * 2017-01-06 2017-05-10 赵阳 Traditional Chinese medicine composition for treating traumatic hematoma and preparation method
CN108434397A (en) * 2018-05-07 2018-08-24 中国医学科学院药用植物研究所 A kind of beauty medicinal moxa roll
CN110327441A (en) * 2019-06-18 2019-10-15 山东中医药大学第二附属医院 A kind of Chinese medicine line spices directly acting on body surface and preparation method
CN111329935A (en) * 2020-04-14 2020-06-26 浙江沃野神生物科技有限公司 Traditional Chinese medicine freckle-removing composition and preparation method and application thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110876788A (en) * 2019-09-26 2020-03-13 遵义红花岗刘端方医院(普通合伙) Traditional Chinese medicine for promoting blood circulation and relieving pain and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1537561A (en) * 2003-04-15 2004-10-20 蚌埠丰原医药科技发展有限公司 Application of Ruzengning and Chinese medicinal composition in preparing medicine for treating chloasma
CN105267657A (en) * 2015-10-16 2016-01-27 施君平 Traditional Chinese medicine preparation for treating female endocrine disorders

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1537561A (en) * 2003-04-15 2004-10-20 蚌埠丰原医药科技发展有限公司 Application of Ruzengning and Chinese medicinal composition in preparing medicine for treating chloasma
CN105267657A (en) * 2015-10-16 2016-01-27 施君平 Traditional Chinese medicine preparation for treating female endocrine disorders

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620533A (en) * 2017-01-06 2017-05-10 赵阳 Traditional Chinese medicine composition for treating traumatic hematoma and preparation method
CN108434397A (en) * 2018-05-07 2018-08-24 中国医学科学院药用植物研究所 A kind of beauty medicinal moxa roll
CN108434397B (en) * 2018-05-07 2021-06-11 中国医学科学院药用植物研究所 A medicated moxa stick for skin care
CN110327441A (en) * 2019-06-18 2019-10-15 山东中医药大学第二附属医院 A kind of Chinese medicine line spices directly acting on body surface and preparation method
CN111329935A (en) * 2020-04-14 2020-06-26 浙江沃野神生物科技有限公司 Traditional Chinese medicine freckle-removing composition and preparation method and application thereof

Also Published As

Publication number Publication date
CN105617290A (en) 2016-06-01

Similar Documents

Publication Publication Date Title
CN104491759B (en) A kind of Chinese medicine composition for treating antimigraine and preparation method thereof
CN106310120A (en) Wide-spectrum traditional Chinese medicine composition water agent and preparation method thereof
CN105617286A (en) Medicine composition which contains Chinese mugwort leaves and has blood circulation promoting and blood stasis removing functions
CN106421649A (en) Traditional Chinese medicine composition for treating cerebral apoplexy and preparation method thereof
CN104940740A (en) Traditional Chinese medicine composition for treating polycystic ovarian syndrome and preparation method thereof
CN104887747A (en) Traditional Chinese medicine composition for treating cerebral thrombosis and preparation method therefor
CN104352793A (en) Traditional Chinese medicine preparation for treating gastrointestinal bleeding and preparation method thereof
CN104435686A (en) Use of traditional Chinese medicine preparation in preparation of medicine for treating skin itch and eczema papulosum
CN104127682A (en) Traditional Chinese medicine for treating alopecia areata
CN105148220A (en) Traditional Chinese medicine for treating spleen-kidney yang deficiency type dizziness and preparation method of traditional Chinese medicine
CN104225507A (en) Chinese medicine for treating limb paralysis and pain caused by cerebral hemorrhage
CN104435567A (en) Traditional Chinese medicinal composition containing gynostemma pentaphyllum for treating gout
CN104857370A (en) Traditional Chinese medicine composition for treating breast cancer
CN101549140B (en) Traditional Chinese medicine composition for treating AIDS and preparation method thereof
CN104840773A (en) Traditional Chinese medicine composition for treating vertebral artery type cervical spondylopathy and method for preparing same
CN104958677A (en) Traditional Chinese medicine preparation for treating membranous nephropathy and preparation method of traditional Chinese medicine preparation
CN104800610A (en) Traditional Chinese medicine preparation for treating Parkinson's disease and preparation method thereof
CN104645247B (en) A kind of Chinese medicine preparation for treating hepatolenticular degeneration and preparation method thereof
CN108704040B (en) Traditional Chinese medicine composition and application thereof
CN105288086A (en) Traditional Chinese medicine composition for treating cerebral thrombosis and preparing method thereof
CN105709060A (en) Application of traditional Chinese medicine preparation in preparing medicine for treating viral myocarditis
CN105194299A (en) Application of traditional Chinese medicine composition in preparation of medicines for treating cerebral thrombosis
CN105012637A (en) Medicine for treating tumors of breasts
CN105250629A (en) Traditional Chinese medicine composition for treating cerebral thrombosis and preparing method thereof
CN105288298A (en) Traditional Chinese medicine preparation for treating cerebral aneurysm sequelae and preparation method of traditional Chinese medicine preparation

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20160601