CN105616679A - Traditional Chinese medicine preparation with effects of nourishing blood and tranquilization and preparation method therefor - Google Patents
Traditional Chinese medicine preparation with effects of nourishing blood and tranquilization and preparation method therefor Download PDFInfo
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- CN105616679A CN105616679A CN201410601187.0A CN201410601187A CN105616679A CN 105616679 A CN105616679 A CN 105616679A CN 201410601187 A CN201410601187 A CN 201410601187A CN 105616679 A CN105616679 A CN 105616679A
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Abstract
The invention discloses a traditional Chinese medicine preparation with effects of nourishing blood and tranquilization and a preparation method therefor. The medicinal preparation is characterized by comprising the following ingredients based on weight percentage: 10-29% of herba agrimoniae, and 10-15% of herba ecliptae, 10-15% of caulis spatholobi, 10-15% of radix rehmanniae, 10-15% of radix rehmaniae recens, 10-15% of cortex albiziae and 10-15% of caulis polygoni multiflori. The traditional Chinese medicine preparation has reasonable matching, synergistic effects of the ingredients, and the effects of nourishing blood and tranquilization, boosting immunity and fatigue resistance; and in addition, the preparation process is simple and the preparation is convenient to carry, so that the traditional Chinese medicine preparation has bright market prospects.
Description
Technical field
The invention belongs to field of pharmaceutical preparations, be specifically related to a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof.
Background technology
Generally aged women, often there will be insomnia and dreamful sleep, skin dark yellow etc., and this is all the situation wanting nourishing blood to tranquillize the mind. The nourishing blood to tranquillize the mind preparation listed at present mainly has pill, syrup, powder. These preparations, the dosage of its Chinese medicine is big, and proportioning is coarse, the therapeutic effect that cost height does not but reach. The present invention is on the basis of traditional handicraft, by reasonably combined prescription, coordinates good process to prepare the Chinese medicine preparation of a kind of nourishing blood to tranquillize the mind, shortens the treatment cycle of Chinese patent medicine, and patient drug's compliance is good.
Summary of the invention
It is desirable to provide a kind for the treatment of cycle is short, eutherapeutic nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof.
For achieving the above object, one nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, its specific embodiments is:
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that this pharmaceutical preparation prescription percentage by weight is calculated as: Herba Agrimoniae 10-29%, Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae, each 10-15% of Caulis Polygoni Multiflori.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that this Chinese medicine preparation preparation method particularly as follows:
(1) Caulis Polygoni Multiflori taking recipe quantity 1/3 is ground into fine powder;
(2) Herba Agrimoniae Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae and remaining 2/3 Caulis Polygoni Multiflori are added 4-12 times of soak by water 1-3 time, each 2-5 hour, collecting decoction, filter;
(3) filtrate is concentrated into relative density is 1.2-1.3, is spray dried to fine powder, adds Caulis Polygoni Multiflori fine powder and adjuvant, and ethanol is granulated, dry, preparation.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that step (2) optimum process: decocting time 2.5-3.5h, multiple 4-8 times that adds water, decoction number of times 2-3 time.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that step (3) preferably 80% ethanol is granulated.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that the described filtrate concentration relative density of step (3) preferably 1.25.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that step (3) described adjuvant is the filler of pharmaceutic adjuvant, binding agent and lubricant.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that this pharmaceutical preparation includes granule, capsule, tablet.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that described filler is one or more in starch, lactose, mannitol, dextrin, microcrystalline Cellulose.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that described wetting agent is one or more in micropowder silica gel, polyethylene glycol 6000, Pulvis Talci.
A kind of nourishing blood to tranquillize the mind Chinese medicine preparation of the present invention and preparation method thereof, it is characterised in that described binding agent is one or more in starch slurry, hydroxypropyl cellulose, sodium carboxymethyl cellulose, polyvinylpyrrolidone, methylcellulose, ethyl cellulose.
Prescription analysis of the present invention:
Herba Agrimoniae: another name Herba silenes fortunei, melon Rhizoma et radix valerianae, old tendon Bovis seu Bubali, wolf wheatgrass. Property flat, bitter in the mouth, puckery. Astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.
Herba Ecliptae: sweet in the mouth acid, cool in nature, enter Liver and kidney two warp, nontoxic. Nourishing the liver and kidney, cooling blood for hemostasis.
Caulis Spatholobi: bitter but slightly sweet taste, warm in nature, returns liver, the heart, kidney channel; There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation.
Radix Rehmanniae: sweet, bitter, cold. GUIXIN, liver, kidney channel. Radix Rehmanniae is cool in nature, sweet-bitter flavor, there are enriching yin and nourishing kidney, nourish blood enrich blood, effect of removing heat from blood.
Radix Rehmanniae: sweet, cold. GUIXIN, liver, kidney channel. Clearing away heat and cooling blood, yin nourishing, promote the production of body fluid.
Cortex Albiziae: sweet, flat. Enter the heart, Liver Channel. Resolving depression and blood, mind calming, subduing inflammation merit. There is the effect controlling irritability, melancholy, insomnia, lung abscess, carbuncle, scrofula, injured bone.
Caulis Polygoni Multiflori: sweet is flat. GUIXIN, Liver Channel. Nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral. For insomnia and dreamful sleep, blood deficiency general pain, rheumatic arthralgia.
The present invention is had nourishing YIN and benefiting blood, the compound Chinese medicinal preparation of mind tranquilizing and the heart calming effect by prepared by Caulis Polygoni Multiflori, Caulis Spatholobi, Radix Rehmanniae Preparata, Radix Rehmanniae, Cortex Albiziae, Herba Ecliptae, Herba Agrimoniae seven flavor medicine altogether. Herba Agrimoniae " astringing to arrest bleeding; preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances ", Herba Ecliptae " nourishing the liver and kidney; cooling blood for hemostasis ", Caulis Spatholobi " relaxing muscles and tendons to promote blood circulation; nourishing blood for regulating menstruation ", Radix Rehmanniae " enriching yin and nourishing kidney, nourish blood and enrich blood ", Radix Rehmanniae " clearing away heat and cooling blood, yin nourishing are promoted the production of body fluid ", Cortex Albiziae " resolving depression and blood, mind calming ", Caulis Polygoni Multiflori " nourishing blood to tranquillize the mind; dispelling wind and removing obstruction in the collateral ", all medicines are instrumental ensembled, and coordinative role is evident in efficacy.
The method have the benefit that
1. formula is reasonable, pure Chinese medicinal preparation, and good effect has no side effect.
2. preparation technology is simple, and easy to operate, production cost is low.
3. preparation convenient drug administration, patient drug's compliance is good.
Detailed description of the invention
Example below, only for further illustrating the present invention, does not limit the present invention in any form.
Embodiment 1
Prescription:Herba Agrimoniae 21 parts, Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae, each 13 parts of Caulis Polygoni Multiflori.
Method for making
(1) Caulis Polygoni Multiflori taking recipe quantity 1/3 is ground into fine powder;
(2) Herba Agrimoniae Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae and remaining 2/3 Caulis Polygoni Multiflori are added 6 times of soak by water 2 times, each 4 hours, collecting decoction, filter;
(3) filtrate is concentrated into relative density is 1.2-1.3, is spray dried to fine powder, adds Caulis Polygoni Multiflori fine powder and adjuvant, and ethanol is granulated, dry, preparation.
Embodiment 2
Prescription:Herba Agrimoniae 21 parts, Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae, each 13 parts of Caulis Polygoni Multiflori.
Method for making
(1) Caulis Polygoni Multiflori taking recipe quantity 1/3 is ground into fine powder;
(2) Herba Agrimoniae Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae and remaining 2/3 Caulis Polygoni Multiflori are added 8 times of soak by water 3 times, each 3 hours, collecting decoction, filter;
(3) filtrate is concentrated into relative density is 1.2-1.3, is spray dried to fine powder, adds Caulis Polygoni Multiflori fine powder and adjuvant, and ethanol is granulated, dry, preparation.
Clinical in 180 example insomnia patientses, 29 ~ 70 years old age, 55 years old mean age, case tcm diagnosis type and therapeutic effect: type of hyperactivity of fire caused by deficiency of YIN 120 example, 112 examples of fully recovering, effective 7 examples, effective 1 example, invalid 0 example; Deficiency of YIN insufficiency of blood type 30 example, 26 examples of fully recovering, effective 2 examples, effective 2 examples, invalid 0 example; Type of deficiency of both the heart and spleen 30 example, 23 examples of fully recovering, effective 5 examples, effective 2 examples, invalid 0 example. Nourishing blood to tranquillize the mind Chinese medicine preparation treated effect 100% of the present invention.
Tablets is taken observation case and is enumerated: once a day, a 1-2 sheet.
Patient, female, 50 years old. Diagnosis in 2009 is type of hyperactivity of fire caused by deficiency of YIN, and dreaminess of easily waking up, every day only sleeps about 3h. Weak, cardiopalmus, dysphoria, complexion is wax yellow. Taking Tablets, sleep and namely recover normal after taking 3 days, every day can sleep 6-7h, and after taking 1 week, weak, cardiopalmus transference cure, complexion improves.
Claims (10)
1. nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof, it is characterised in that this pharmaceutical preparation prescription percentage by weight is calculated as: Herba Agrimoniae 10-29%, Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae, each 10-15% of Caulis Polygoni Multiflori.
2. nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof, it is characterised in that this Chinese medicine preparation preparation method particularly as follows:
(1) Caulis Polygoni Multiflori taking recipe quantity 1/3 is ground into fine powder;
(2) Herba Agrimoniae Herba Ecliptae, Caulis Spatholobi, Radix Rehmanniae, Radix Rehmanniae, Cortex Albiziae and remaining 2/3 Caulis Polygoni Multiflori are added 4-12 times of soak by water 1-3 time, each 2-5 hour, collecting decoction, filter;
(3) filtrate is concentrated into relative density is 1.2-1.3, is spray dried to fine powder, adds Caulis Polygoni Multiflori fine powder and adjuvant, and ethanol is granulated, dry, preparation.
3. require described in 2 a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof according to power, it is characterised in that step (2) optimum process: decocting time 2.5-3.5h, multiple 4-8 times that adds water, decoction number of times 2-3 time.
4. require a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof described in 2 according to power, it is characterised in that step (3) preferably 80% ethanol is granulated.
5. require described in 2 a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof according to power, it is characterised in that the described filtrate concentration relative density of step (3) preferably 1.25.
6. require a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof described in 2 according to power, it is characterised in that step (3) described adjuvant is the filler of pharmaceutic adjuvant, binding agent and lubricant.
7. require a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof described in 2 according to power, it is characterised in that this pharmaceutical preparation includes granule, capsule, tablet.
8. a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof according to claim 6, it is characterised in that described filler is one or more in starch, lactose, mannitol, dextrin, microcrystalline Cellulose.
9. a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof according to claim 6, it is characterised in that described wetting agent is one or more in micropowder silica gel, polyethylene glycol 6000, Pulvis Talci.
10. a kind of nourishing blood to tranquillize the mind Chinese medicine preparation and preparation method thereof according to claim 6, it is characterised in that described binding agent is one or more in starch slurry, hydroxypropyl cellulose, sodium carboxymethyl cellulose, polyvinylpyrrolidone, methylcellulose, ethyl cellulose.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410601187.0A CN105616679A (en) | 2014-11-01 | 2014-11-01 | Traditional Chinese medicine preparation with effects of nourishing blood and tranquilization and preparation method therefor |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878551A (en) * | 2016-06-02 | 2016-08-24 | 林正秋 | Medicine microfilaments with tranquilizing effect and preparation method thereof |
| CN107029125A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | A kind of calm the nerves improves granule medicament formula of sleep and preparation method thereof |
| CN107320564A (en) * | 2017-07-03 | 2017-11-07 | 广西大海阳光药业有限公司 | A kind of Chinese medicine preparation for treating vertigo and palpitation, insomnia forgetfulness and preparation method thereof |
| CN107362272A (en) * | 2017-08-31 | 2017-11-21 | 江西金顶药业有限公司 | A kind of Yangxue Anshen Syrup |
-
2014
- 2014-11-01 CN CN201410601187.0A patent/CN105616679A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878551A (en) * | 2016-06-02 | 2016-08-24 | 林正秋 | Medicine microfilaments with tranquilizing effect and preparation method thereof |
| CN107029125A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | A kind of calm the nerves improves granule medicament formula of sleep and preparation method thereof |
| CN107320564A (en) * | 2017-07-03 | 2017-11-07 | 广西大海阳光药业有限公司 | A kind of Chinese medicine preparation for treating vertigo and palpitation, insomnia forgetfulness and preparation method thereof |
| CN107362272A (en) * | 2017-08-31 | 2017-11-21 | 江西金顶药业有限公司 | A kind of Yangxue Anshen Syrup |
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