CN105596262A - Anti-wrinkle firming eye cream and preparation method thereof - Google Patents
Anti-wrinkle firming eye cream and preparation method thereof Download PDFInfo
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Abstract
The invention relates to the field of cosmetics, and particularly relates to an anti-wrinkle firming eye cream and a preparation method thereof. The anti-wrinkle firming eye cream is prepared from the following raw materials: a phase A including glycerinum, hexylene glycol, hyaluronic acid, oat bran extract, PVM/MA decadiene crosslinked polymer and water, a phase B including shea butter, polydimethylsiloxane and caprylic/capric triglyceride, a phase C including sodium hydroxide and water, a phase D including sodium polyacrylate, vitamin E acetate, vitamin A palmitate and coenzyme Q10, a phase E including D-pantothenyl alcohol and nicotinamide, and a phase F including gingko extract, tetrandrine and phenoxyethanol. The anti-wrinkle firming eye cream is prepared from raw materials which are synergized and enhanced, and can effectively infiltrate into the corium layer of skin to repair the impaired collagen structure, nourish impaired cells, deeply improve skin problems and restore elasticity of periocular skin, so that the periocular skin is white, tender, smooth and elastic; and the anti-wrinkle firming eye cream has strong permeable feeling, so that the remarkable effects of removing wrinkles and firming the periocular skin can be achieved.
Description
Technical field
The present invention relates to cosmetic field, in particular to a kind of anti-wrinkle compact eye cream andIts preparation method.
Background technology
Along with the raising of living standards of the people and the demand to self health, various beauty and make-upsProduct more and more come into one's own. The problem that perplexs the most women is, as time goes by, and eyeAlso there is wrinkle and sagging etc. a series of skin problems of pouch, canthus in portion's cutis laxa.
Compact effect of eye cream of existing anti-wrinkle is still difficult to reach people's requirement.
In view of this, special proposition the present invention.
Summary of the invention
The first object of the present invention is to provide a kind of anti-wrinkle eye cream that compacts, and described wrinkle is compactedEye cream can effectively infiltrate skin skin corium, repairs impaired collagen structure, nourishes damaged cell,The degree of depth is improved skin problem, recovers skin elasticity near the eyes, reaches obvious anti-wrinkle and the eye that compactsThe effect of portion's skin.
The preparation side that the second object of the present invention is to provide a kind of described anti-wrinkle to compact eye creamMethod, the method is well miscible in each raw material together, and each feed distribution homogeneous, obtainsThe anti-wrinkle eye cream good penetrability of compacting, easily absorbs, and clearly and not glutinous greasy after use, safety is without secondaryEffect.
In order to realize above-mentioned purpose of the present invention, spy by the following technical solutions:
A kind of anti-wrinkle eye cream that compacts, is prepared from by the raw material of following parts by weight:
A phase: glycerine 3.5-4.5 part, hexylene glycol 0.5-0.7 part, hyaluronic acid 0.05-0.15Part, oat bran extract 4.5-5.5 part, PVM/MA decadiene crosslinked polymer 0.4-0.6Part, water 55-65 part;
B phase: shea butter 3.5-4.5 part, dimethyl silicone polymer 0.5-1.5 part, sadTriglyceride DDD 3.5-4.5 part;
C phase: NaOH 0.10-0.15 part, water 0.8-1.5 part;
D phase: Sodium Polyacrylate 0.4-0.6 part, vitamin e acetate 0.3-0.5 part, dimensionRaw plain A palmitate 0.05-0.15 part, Co-Q10 0.1-0.3 part;
E phase: D-pantothenyl aleohol 0.2-0.4 part, niacinamide 0.5-1.5 part;
F phase: ginkgo biloba extract 5-10 part, hanfangchin A 0.25-0.35 part, Phenoxyethanol0.2-0.4 part.
Each raw material is carried out to following explanation:
1. deionized water: as solvent, water is to make the most basic raw material in cosmetics,Can be distilled water or deionized water;
2. glycerine: conventional NMF, uses as solvent and NMF at this formula;
3. hexylene glycol: the NMF raw material that newly puts goods on the market and use, has auxiliary anticorrosionEffect, safety;
4. hyaluronic acid: one of the most frequently used NMF, moistening effect is good, does not stimulate;
5. oat bran extract: from oat bran, extract, have moisturizing, anti-ageing,Anti-quick effect, can reduce the stimulation of cosmetic material to skin, and this raw material can be by commercially availableBuy;
6.PVM/MA decadiene crosslinked polymer: thickener/emulsifier, safe and non-stimulating;
7. shea butter: the grease of natural origin, owing to containing the anti-quick one-tenth of multiple sterolsPoint, be used in the cosmetics of super quality more, there are moisturizing, anti-quick, anti-inflammatory texts;
8. dimethyl silicone polymer: commonly use grease, improve the use sense of lotion;
9. caprylic/capric triglyceride: one of the most frequently used grease, safety, moisturizing is effective;
10. NaOH: inorganic base is acidity-basicity regulator, and purity is high, can not bring intoOther dangerous material;
11. Sodium Polyacrylates: thickener/emulsifier, makes cream frost fine and smooth, bright;
12. vitamin e acetates: extraordinary antioxidant, make skin moisten, moisturizing,Whitening, anti-ageing prevents that other vegetable fat from becoming sour simultaneously;
13. Retinol Palmitates: after vitamin A is absorbed by the skin, can promote skinThe generation of top layer collagen, makes skin full, flexible, to reducing changing of tiny wrinkleKind respond well;
14. Co-Q10s: extraordinary antioxidant, have whitening, anti-ageing, go the merits such as wrinkleEffect;
15.D-panthenol: claim again dexpanthenol, the nursing role on skin shows as deeplyThe NMF that enters infiltration, stimulates epithelial growth, promotes wound healing, plays anti-inflammatory and doesWith;
16. niacinamide: vitamin B3, water soluble vitamin, Sage Extract, can allow skinWhitening, have inhibitory action to black;
17. ginkgo biloba extracts: the polysaccharide extracting from ginkgo nut and small-molecular peptides, have moisturizing,The effects such as anti-ageing, whitening, anti-quick, Sage Extract;
18. hanfangchin As:; The effects such as that this raw material has is anti-ageing, whitening, anti-quick anti-inflammatory,Use in cosmetics as novel cosmetic additive, evident in efficacy;
19. Phenoxyethanols: conventional anticorrisive agent in cosmetics is European Union, Japan, ChinaThe anticorrisive agent of the safety of accreditation.
The anti-wrinkle provided by the invention eye cream that compacts is by different ratios by out of phase each raw materialExample is mixed with and forms, and between each raw material, coordinated strengthens, and effectively infiltrates skin skin corium,Repair impaired collagen structure, nourish damaged cell, the degree of depth is improved skin problem, recovers near the eyesSkin elasticity, makes that skin and muscles are fair near the eyes tender, moist high resilience, and penetrating sense strengthens, and reachesTo the effect of obvious anti-wrinkle and the eye skin that compacts.
In order further to strengthen the collaborative enhancing effect between each raw material, preferably, byThe raw material of following parts by weight is prepared from:
A phase: glycerine 3.8-4.2 part, hexylene glycol 0.55-0.65 part, hyaluronic acid 0.08-0.12Part, oat bran extract 4.8-5.2 part, PVM/MA decadiene crosslinked polymer0.45-0.55 part, water 58-62 part;
B phase: shea butter 3.8-4.2 part, dimethyl silicone polymer 0.8-1.2 part, sadTriglyceride DDD 3.8-4.2 part;
C phase: NaOH 0.12-0.13 part, water 0.9-1.1 part;
D phase: Sodium Polyacrylate 0.48-0.50 part, vitamin e acetate 0.38-0.42 part,Retinol Palmitate 0.08-0.12 part, Co-Q10 0.15-0.25 part;
E phase: D-pantothenyl aleohol 0.25-0.35 part, niacinamide 0.8-1.2 part;
F phase: ginkgo biloba extract 6-8 part, hanfangchin A 0.30-0.32 part, Phenoxyethanol0.28-0.30 part.
More preferably, be prepared from by the raw material of following parts by weight:
A phase: glycerine 3.9-4.0 part, hexylene glycol 0.58-0.60 part, hyaluronic acid 0.09-0.10Part, oat bran extract 5.0-5.1 part, PVM/MA decadiene crosslinked polymer0.58-0.50 part, water 59-60 part;
B phase: shea butter 3.9-4.1 part, dimethyl silicone polymer 0.9-1.0 part, sadTriglyceride DDD 3.9-4.0 part;
C phase: NaOH 0.12-0.13 part, water 0.9-1.1 part;
D phase: Sodium Polyacrylate 0.49-0.50 part, vitamin e acetate 0.39-0.41 part,Retinol Palmitate 0.09-0.11 part, Co-Q10 0.18-0.22 part;
E phase: D-pantothenyl aleohol 0.28-0.32 part, niacinamide 0.9-1.1 part;
F phase: ginkgo biloba extract 7-8 part, hanfangchin A 0.30-0.32 part, Phenoxyethanol0.29-0.30 part.
Further, described ginkgo biloba extract is prepared by the following method:
(a), more than ginkgo nut pulverizes 50 orders, the water that adds ginkgo nut 3-8 doubly to measure, in58-65 DEG C of lixiviate 55-65min, obtains mixture;
(b), add the alpha-amylase of the 1%-3% of described mixture weight, temperature raisesTo 75-83 DEG C, enzymolysis 55-65min;
(c), be cooled to 28-35 DEG C, adopt diatomite filtration, to obtain final product.
Ginkgo nut adds flooding after pulverizing, and water used is generally distilled water, by oneLixiviate a period of time under fixed temperature, ginkgo nut cell is fully swelling; Then add appropriate heightTemperature amylase, selects enzymolysis a period of time under 75-83 DEG C of condition, alpha-amylase usedPeak enzymolysis-ability temperature is more than 90 DEG C, and maximum temperature reaches more than 100 degree Celsius, but experiment is sent outExisting, hydrolysis temperature exceedes 85 DEG C, after ginkgo nut enzymolysis, and the extract muddiness finally obtaining;And between 75-83 DEG C, the extract finally obtaining is limpid, and effective active component contentHigh.
Wherein, alpha-amylase generally uses high temperature resistant AMS, buys by commercially availableArrive.
Preferably, in step (a), the granularity that described ginkgo nut is pulverized is 100-200 order.It is high that the ginkgo nut of this granularity extracts the effective active component content obtaining, and the solution obtaining is clearClear.
Preferably, in step (a), the weight ratio of water and ginkgo nut is 4-6:1.
In enzymolysis product, contain organic principle and the pigments such as a lot of greases, be difficult to remove,The present invention is through test of many times, and the specific atlapulgite of selecting, adsorbs coloring matter wherein and haveMachine material, for the filtration of next step diatom provides good basis. Preferably, at step (c)In, before described diatomite filtration, also comprise the step that adopts atlapulgite to filter.
Diatomite pH value is neutral, and nontoxic, suspendability is good, and absorption property is strong, can have1 micron of even particulate or microorganism of 0.1 micron in effect treat liquid.
Through test, appropriate diatomite and atlapulgite can reach better filter effect.
Preferably, in step (c), the addition of described atlapulgite is water and ginkgo nutThe 25%-30% of gross weight;
Described diatomaceous addition is the 15%-20% of water and ginkgo nut gross weight.
Atlapulgite filters and diatom is filtered preferably employing filter plate negative pressure of vacuum filtration, to reachBetter filter effect, and filter efficient quick.
Biological activated carbon has good suction-operated, removes particulate or impurity, sends out through testExisting, after diatomite filtration, increase the filtration step of biological activated carbon, further remove impurity,And increase the electrical conductance of solution. Preferably, in step (c), described diatomiteAfter filtering, also comprise the step that adopts biologic active carbon filtration;
The addition of described biological activated carbon is the 7%-10% of water and ginkgo nut gross weight.
Before and after biologic active carbon filtration, the electrical conductivity of solution is become from 150-200 μ S/cm785-790μS/cm。
Ginkgo biloba extract provided by the invention, takes from ginkgo Embryonic germ cells, and nutritional labeling is richRichness, detects through refractometry, and solubility solid content is at 4.7%-5.3%; Measure silver-colored with HPLCApricot fruit polyoses content is at 2.5%-2.8%, and micromolecule polypeptide content is at 0.12%-0.15%, galaSugar content is at 0.67%-0.7%, and glucose content is at 0.08%-0.10%, and Xylose Content exists0.13%-0.15%, flavonoid of ginkgo biloba is at 0.05%-0.08%; And other a small amount of material is:Ginkgo tartaric acid < 1ppm, ginkgolides 0.03%-0.05%, hydroginkgoic acid < 1ppm etc.; WarpMeasure, electrical conductivity is 785-790 μ S/cm.
The anti-wrinkle provided by the invention eye cream ginkgo biloba extract used that compacts can adopt commercially available silverApricot leaf extract, also can adopt ginkgo nut extract provided by the invention. Employing the present invention carryThe ginkgo nut extract of confession, the anti-wrinkle successful that compacts is better than commercially available ginkgo biloba p.e.
The preparation method that the present invention also provides described anti-wrinkle to compact eye cream, comprises following stepRapid:
By A heat phase, to 84-86 DEG C, insulation 28-35 minute, is then cooled to 48-52 DEG C,Add C phase, stir, obtain the mixture of A phase and C phase;
B heat phase, to 58-62 DEG C, is incubated to 8-15 minute;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 8-15 minute;
Vacuum homogeneous 3-5 minute, then stir cooling in 8-15 minute, when temperature is 44-46 DEG C,Add E phase, vacuumize and stir 8-15 minute;
Be cooled to 38-42 DEG C, add F phase, vacuumize slow stirring 8-15 minute.
The compact preparation method of eye cream of anti-wrinkle provided by the invention, by progressively by out of phaseEach raw material mixes, and each raw material is better miscible in together, quality controllable, makesThe anti-wrinkle each component distributing homogeneous of eye cream that compacts, be rich in gloss, exquisiteness, ductility good, makeWith rear, good penetrability, easily absorbs, and clearly and not glutinous greasy, safety has no side effect.
For better that raw material is miscible, preferably, the rotating speed of stirring is 30-50r/min.
Preferably, the rotating speed of described slow stirring is 10-20r/min.
Compared with prior art, beneficial effect of the present invention is:
(1) the anti-wrinkle provided by the invention eye cream that compacts, between each raw material, coordinated strengthens,Effectively infiltrate skin skin corium, repair impaired collagen structure, nourish damaged cell, the degree of depth changesKind skin problem, recovers skin elasticity near the eyes, makes that skin and muscles are fair near the eyes tender, moist richElasticity, penetrating sense strengthens, and reaches obvious anti-wrinkle and the effect of the eye skin that compacts.
(2) the present invention has also further optimized the proportioning between each raw material, with furtherIncrease the collaborative enhancing effect between each raw material.
(3) the present invention also provides the preparation method of ginkgo biloba extract, and this ginkgo nut extractsThing is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, and has stronger electrical conductance,Greatly increased the compact performance of eye cream of anti-wrinkle.
(4) the present invention also provides the preparation method that anti-wrinkle is compacted eye cream, by progressivelyOut of phase each raw material mixes, and each raw material is better miscible in together, and quality canControl, the anti-wrinkle the making each component distributing homogeneous of eye cream that compacts, is rich in gloss, exquisiteness, extensionProperty good, after use, good penetrability, easily absorbs, clearly and not glutinous greasy, safety has no side effect.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but thisThose skilled in the art will be understood that, the following example is only for the present invention is described, and should not lookFor limiting the scope of the invention. Unreceipted actual conditions person in embodiment, according to normal conditionOr the condition of manufacturer's suggestion is carried out. The unreceipted person of production firm of agents useful for same or instrument, allFor can be by the conventional products of commercially available acquisition.
Embodiment 1
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 3.5 parts of glycerine, 0.5 part of hexylene glycol, 0.05 part of hyaluronic acid, oat bran4.5 parts of bark extracts, 0.4 part of PVM/MA decadiene crosslinked polymer, 55 parts, water;
B phase: 3.5 parts of shea butters, 0.5 part of dimethyl silicone polymer, sad capric acid glycerineThree 3.5 parts of esters;
C phase: 0.10 part, NaOH, 0.8 part, water;
D phase: 0.4 part of Sodium Polyacrylate, 0.3 part of vitamin e acetate, vitamin A0.05 part of palmitate, 0.1 part of Co-Q10;
E phase: 0.2 part of D-pantothenyl aleohol, 0.5 part of niacinamide;
F phase: 5 parts of ginkgo biloba extracts, 0.25 part of hanfangchin A, 0.2 part of Phenoxyethanol;
By A heat phase to 84 DEG C, be incubated 35 minutes, be then cooled to 48 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 58 DEG C, be incubated 15 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 8 minutes;
Vacuum homogeneous 3 minutes, then stir cooling in 8 minutes, when temperature is 44 DEG C, add EPhase, vacuumizes and stirs 15 minutes;
Be cooled to 38 DEG C, add F phase, vacuumize slow stirring 15 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 50 orders, adds water, water and ginkgo nutWeight ratio be 8:1, in 65 DEG C of lixiviate 55min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo3% of fruit gross weight, temperature is increased to 75 DEG C, enzymolysis 65min;
(c), be cooled to 28 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 30% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 15% of water and ginkgo nut gross weight, and the addition of biological activated carbon is7% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo biloba extract of transparency liquid.
This ginkgo biloba extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractometryDetect, solubility solid content is 5.3%; Measure ginkgo nut polyoses content 2.5% with HPLC,Micromolecule polypeptide content is 0.12%, and galactose content is 0.67%, and glucose content exists0.10%, Xylose Content is 0.13%, and flavonoid of ginkgo biloba is 0.07%; And other is a small amount ofMaterial is: ginkgo tartaric acid < 1ppm, ginkgolides 0.03%, hydroginkgoic acid < 1ppm etc.;After measured, electrical conductivity is 785 μ S/cm.
Embodiment 2
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 3.8 parts of glycerine, 0.55 part of hexylene glycol, 0.08 part of hyaluronic acid, oat bran4.8 parts of bark extracts, 0.45 part of PVM/MA decadiene crosslinked polymer, 58 parts, water;
B phase: 3.8 parts of shea butters, 0.8 part of dimethyl silicone polymer, sad capric acid glycerineThree 3.8 parts of esters;
C phase: 0.12 part, NaOH, 0.9 part, water;
D phase: 0.48 part of Sodium Polyacrylate, 0.38 part of vitamin e acetate, vitamin A0.08 part of palmitate, 0.15 part of Co-Q10;
E phase: 0.25 part of D-pantothenyl aleohol, 0.8 part of niacinamide;
F phase: 6 parts of ginkgo biloba extracts, 0.30 part of hanfangchin A, 0.28 part of Phenoxyethanol;
By A heat phase to 85 DEG C, be incubated 30 minutes, be then cooled to 50 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 60 DEG C, be incubated 10 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 10 minutes;
Vacuum homogeneous 4 minutes, then stir cooling in 10 minutes, when temperature is 45 DEG C, add EPhase, vacuumizes and stirs 10 minutes;
Be cooled to 40 DEG C, add F phase, vacuumize slow stirring 10 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 100 orders, adds water, water and ginkgoThe weight ratio of fruit is 5:1, in 60 DEG C of lixiviate 60min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo2% of fruit gross weight, temperature is increased to 80 DEG C, enzymolysis 60min;
(c), be cooled to 30 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 28% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 18% of water and ginkgo nut gross weight, and the addition of biological activated carbon is8% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo biloba extract of transparency liquid.
This ginkgo biloba extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractometryDetect, solubility solid content is 5.0%; Measure ginkgo nut polyoses content 2.8% with HPLC,Micromolecule polypeptide content is 0.14%, and galactose content is 0.68%, and glucose content exists0.08%, Xylose Content is 0.15%, and flavonoid of ginkgo biloba is 0.08%; And other is a small amount ofMaterial is: ginkgo tartaric acid < 1ppm, ginkgolides 0.05%, hydroginkgoic acid < 1ppm etc.;After measured, electrical conductivity is 788 μ S/cm.
Embodiment 3
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 3.9 parts of glycerine, 0.58 part of hexylene glycol, 0.09 part of hyaluronic acid, oat bran5.0 parts of bark extracts, 0.58 part of PVM/MA decadiene crosslinked polymer, 59 parts, water;
B phase: 3.9 parts of shea butters, 0.9 part of dimethyl silicone polymer, sad capric acid glycerineThree 3.9 parts of esters;
C phase: 0.12 part, NaOH, 0.9 part, water;
D phase: 0.49 part of Sodium Polyacrylate, 0.39 part of vitamin e acetate, vitamin A0.09 part of palmitate, 0.18 part of Co-Q10;
E phase: 0.28 part of D-pantothenyl aleohol, 0.9 part of niacinamide;
F phase: 7 parts of ginkgo biloba extracts, 0.30 part of hanfangchin A, 0.29 part of Phenoxyethanol;
By A heat phase to 86 DEG C, be incubated 28 minutes, be then cooled to 52 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 62 DEG C, be incubated 8 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 10 minutes;
Vacuum homogeneous 5 minutes, then stir cooling in 8 minutes, when temperature is 46 DEG C, add EPhase, vacuumizes and stirs 8 minutes;
Be cooled to 42 DEG C, add F phase, vacuumize slow stirring 8 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 200 orders, adds water, water and ginkgoThe weight ratio of fruit is 3:1, in 58 DEG C of lixiviate 65min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo1% of fruit gross weight, temperature is increased to 83 DEG C, enzymolysis 55min;
(c), be cooled to 35 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 25% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 20% of water and ginkgo nut gross weight, and the addition of biological activated carbon is10% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo biloba extract of transparency liquid.
This ginkgo biloba extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractometryDetect, solubility solid content is 4.7%; Measure ginkgo nut polyoses content 2.6% with HPLC,Micromolecule polypeptide content is 0.13%, and galactose content is 0.7%, and glucose content exists0.09%, Xylose Content is 0.14%, and flavonoid of ginkgo biloba is 0.05%; And other is a small amount ofMaterial is: ginkgo tartaric acid < 1ppm, ginkgolides 0.04%, hydroginkgoic acid < 1ppm etc.;After measured, electrical conductivity is 786 μ S/cm.
Embodiment 4
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 4.0 parts of glycerine, 0.60 part of hexylene glycol, 0.10 part of hyaluronic acid, oat bran5.1 parts of bark extracts, 0.50 part of PVM/MA decadiene crosslinked polymer, 60 parts, water;
B phase: 4.1 parts of shea butters, 1.0 parts of dimethyl silicone polymers, sad capric acid glycerineThree 4.0 parts of esters;
C phase: 0.13 part, NaOH, 1.1 parts, water;
D phase: 0.50 part of Sodium Polyacrylate, 0.41 part of vitamin e acetate, vitamin A0.11 part of palmitate, 0.22 part of Co-Q10;
E phase: 0.32 part of D-pantothenyl aleohol, 1.1 parts of niacinamide;
F phase: 8 parts of ginkgo biloba extracts, 0.32 part of hanfangchin A, 0.30 part of Phenoxyethanol;
By A heat phase to 85 DEG C, be incubated 32 minutes, be then cooled to 50 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 60 DEG C, be incubated 12 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 10 minutes;
Vacuum homogeneous 5 minutes, then stir cooling in 10 minutes, when temperature is 45 DEG C, add EPhase, vacuumizes and stirs 12 minutes;
Be cooled to 40 DEG C, add F phase, vacuumize slow stirring 12 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 150 orders, adds water, water and ginkgoThe weight ratio of fruit is 6:1, in 62 DEG C of lixiviate 60min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo2% of fruit gross weight, temperature is increased to 78 DEG C, enzymolysis 60min;
(c), be cooled to 32 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 27% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 18% of water and ginkgo nut gross weight, and the addition of biological activated carbon is10% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo biloba extract of transparency liquid.
This ginkgo biloba extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractometryDetect, solubility solid content is 5.1%; Measure ginkgo nut polyoses content 2.8% with HPLC,Micromolecule polypeptide content is 0.15%, and galactose content is 0.67%, and glucose content exists0.08%, Xylose Content is 0.13%, and flavonoid of ginkgo biloba is 0.08%; And other is a small amount ofMaterial is: ginkgo tartaric acid < 1ppm, ginkgolides 0.05%, hydroginkgoic acid < 1ppm etc.;After measured, electrical conductivity is 790 μ S/cm.
Embodiment 5
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 4.2 parts of glycerine, 0.65 part of hexylene glycol, 0.12 part of hyaluronic acid, oat bran5.2 parts of bark extracts, 0.55 part of PVM/MA decadiene crosslinked polymer, 62 parts, water;
B phase: 4.2 parts of shea butters, 1.2 parts of dimethyl silicone polymers, sad capric acid glycerineThree 4.2 parts of esters;
C phase: 0.12 part, NaOH, 1 part, water;
D phase: 0.50 part of Sodium Polyacrylate, 0.42 part of vitamin e acetate, vitamin A0.12 part of palmitate, 0.25 part of Co-Q10;
E phase: 0.35 part of D-pantothenyl aleohol, 1.2 parts of niacinamide;
F phase: 8 parts of ginkgo biloba extracts, 0.32 part of hanfangchin A, 0.30 part of Phenoxyethanol;
By A heat phase to 86 DEG C, be incubated 30 minutes, be then cooled to 50 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 60 DEG C, be incubated 10 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 10 minutes;
Vacuum homogeneous 5 minutes, then stir cooling in 10 minutes, when temperature is 45 DEG C, add EPhase, vacuumizes and stirs 10 minutes;
Be cooled to 40 DEG C, add F phase, vacuumize slow stirring 10 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 150 orders, adds water, water and ginkgoThe weight ratio of fruit is 6:1, in 62 DEG C of lixiviate 60min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo2% of fruit gross weight, temperature is increased to 78 DEG C, enzymolysis 60min;
(c), be cooled to 32 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 27% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 18% of water and ginkgo nut gross weight, and the addition of biological activated carbon is10% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo nut extract of transparency liquid.
This ginkgo nut extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractive powerMethod detects, and solubility solid content is 5.1%; Measuring ginkgo nut polyoses content with HPLC exists2.8%, micromolecule polypeptide content is 0.15%, and galactose content is 0.67%, and glucose containsAmount is 0.08%, and Xylose Content is 0.13%, and flavonoid of ginkgo biloba is 0.08%; And otherA small amount of material is: ginkgo tartaric acid < 1ppm, ginkgolides 0.05%, hydroginkgoic acid < 1ppmDeng; After measured, electrical conductivity is 790 μ S/cm.
Embodiment 6
Adopt following methods to prepare the anti-wrinkle eye cream that compacts:
First, prepare each raw material by following weight portion:
A phase: 4.5 parts of glycerine, 0.7 part of hexylene glycol, 0.15 part of hyaluronic acid, oat bran5.5 parts of bark extracts, 0.6 part of PVM/MA decadiene crosslinked polymer, 65 parts, water;
B phase: 4.5 parts of shea butters, 1.5 parts of dimethyl silicone polymers, sad capric acid glycerineThree 4.5 parts of esters;
C phase: 0.15 part, NaOH, 1.5 parts, water;
D phase: 0.6 part of Sodium Polyacrylate, 0.5 part of vitamin e acetate, vitamin A0.15 part of palmitate, 0.3 part of Co-Q10;
E phase: 0.4 part of D-pantothenyl aleohol, 1.5 parts of niacinamide;
F phase: 10 parts of ginkgo biloba extracts, 0.35 part of hanfangchin A, 0.4 part of Phenoxyethanol;
By A heat phase to 84 DEG C, be incubated 35 minutes, be then cooled to 52 DEG C, add CPhase, stirs, and obtains the mixture of A phase and C phase;
By B heat phase to 60 DEG C, be incubated 10 minutes;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 10 minutes;
Vacuum homogeneous 5 minutes, then stir cooling in 15 minutes, when temperature is 46 DEG C, add EPhase, vacuumizes and stirs 8 minutes;
Be cooled to 340 DEG C, add F phase, vacuumize slow stirring 10 minutes.
Wherein, ginkgo biloba extract is prepared by the following method:
(a), ginkgo nut pulverize, the granularity of pulverizing is 100 orders, adds water, water and ginkgoThe weight ratio of fruit is 5:1, in 60 DEG C of lixiviate 60min;
(b), then add alpha-amylase, the addition of alpha-amylase is water and ginkgo2% of fruit gross weight, temperature is increased to 80 DEG C, enzymolysis 60min;
(c), be cooled to 30 DEG C, carry out successively atlapulgite filtration, diatomite filtration, lifeThing activated carbon filtration, the addition of atlapulgite is 28% of water and ginkgo nut gross weight, siliconThe addition of algae soil is 18% of water and ginkgo nut gross weight, and the addition of biological activated carbon is8% of water and ginkgo nut gross weight;
In addition, the particle diameter of biological activated carbon is below 100 μ m, and biological activated carbon is commercially available strawStalk active carbon;
The filtered fluid obtaining is the ginkgo biloba extract of transparency liquid.
This ginkgo biloba extract is taken from ginkgo Embryonic germ cells, and nutritional labeling is abundant, through refractometryDetect, solubility solid content is 5.0%; Measure ginkgo nut polyoses content 2.8% with HPLC,Micromolecule polypeptide content is 0.14%, and galactose content is 0.68%, and glucose content exists0.08%, Xylose Content is 0.15%, and flavonoid of ginkgo biloba is 0.08%; And other is a small amount ofMaterial is: ginkgo tartaric acid < 1ppm, ginkgolides 0.05%, hydroginkgoic acid < 1ppm etc.;After measured, electrical conductivity is 788 μ S/cm.
Comparative example
Ginkgo biloba extract in embodiment 1-6 is changed to commercially available ginkgo biloba p.e, otherPart is constant, makes respectively the anti-wrinkle eye cream control group 1-6 that compacts.
Control group 7-9 removes the ginkgo biloba extract in embodiment 2-4, and all the other compositions are notBecome the eye cream of making according to identical preparation method.
Control group 10 uses the multiple dual eye essence breast that lifts of face of L'Oreal (LOREAL).
The anti-wrinkle that embodiment 1-6 and control group 1-9 make is compacted eye cream according to the rule of cosmeticsFixed detection, meets the pertinent regulations requirement of QB/T1857-2013, and organoleptic indicator is as lookPool, fragrance, structure meet industry regulation, and physical and chemical index is as pH, heat-resisting, cold-resistant and activeThing all meets industry regulation, and cosmetics are at the top of one's class. To the compact safety of eye cream of different anti-wrinkleProperty detects, and meets cosmetics health specification, illustrates and uses safety.
Experimental example 1
The eye cream of embodiment 1-6 and control group 1-10 is carried out respectively to compliance test result. Concrete asUnder: select a middle-aged person in 1600 35-50 year, be divided into 16 groups, different groups are respectivelyUse the eye cream of making separately, using method is: after clean face, get the eye of grain of rice sizeFrost smears to eye surrounding, and flicking absorbs, and every day is each use once sooner or later, adheres to makingWith 1 month. Respectively disparity items is given a mark according to change of skin, disparity items comprisesPermeability, comfort level (comprise and use salubrious property and moistness), wrinkle change (from 60 pointsShowing as wrinkle to 100 points reduces or refine to the level loseing completely), skin elasticity (from60 assign to 100 points show as skin elasticity be promoted to gradually reach skin as baby), compact(assign to 100 points from 60 shows as skin-tightening degree and is promoted to gradually and reaches flesh as baby effectSkin), each project full marks are 100 points. Statistics marking result, then averages, and obtainsWhole appraisal result. Concrete outcome is in table 1.
Table 1 appraisal result
In use find the anti-wrinkle that uses embodiment of the present invention 1-6 the to make eye that compactsFrost, not only susceptibility is better, and to the improvement of wrinkle, skin elasticity and the effect of compacting alsoObviously be better than using commercially available ginkgo biloba p.e, be more better than not adding the eye cream of ginkgo biloba extract;With respect to commercially available eye cream, effect also obviously strengthens.
In a word, anti-wrinkle provided by the invention is compacted and is worked in coordination with and strengthen between the each raw material of eye cream, can haveEffect is infiltrated skin skin corium, repairs impaired collagen structure, nourishes damaged cell, and the degree of depth is improvedSkin problem, recovers skin elasticity near the eyes, makes that skin and muscles are fair near the eyes tender, and moist be rich in bulletProperty, penetrating sense strengthens, and reaches obvious anti-wrinkle and the effect of the eye skin that compacts.
Although illustrated and described the present invention with specific embodiment, but it will be appreciated thatIn the situation that not deviating from the spirit and scope of the present invention, can make many other change andAmendment. Therefore, this means in claims and comprise and belonging in the scope of the inventionAll such changes and modifications.
Claims (10)
1. the anti-wrinkle eye cream that compacts, is characterized in that, by the raw material of following parts by weightBe prepared from:
A phase: glycerine 3.5-4.5 part, hexylene glycol 0.5-0.7 part, hyaluronic acid 0.05-0.15Part, oat bran extract 4.5-5.5 part, PVM/MA decadiene crosslinked polymer 0.4-0.6Part, water 55-65 part;
B phase: shea butter 3.5-4.5 part, dimethyl silicone polymer 0.5-1.5 part, sadTriglyceride DDD 3.5-4.5 part;
C phase: NaOH 0.10-0.15 part, water 0.8-1.5 part;
D phase: Sodium Polyacrylate 0.4-0.6 part, vitamin e acetate 0.3-0.5 part, dimensionRaw plain A palmitate 0.05-0.15 part, Co-Q10 0.1-0.3 part;
E phase: D-pantothenyl aleohol 0.2-0.4 part, niacinamide 0.5-1.5 part;
F phase: ginkgo biloba extract 5-10 part, hanfangchin A 0.25-0.35 part, Phenoxyethanol0.2-0.4 part.
2. the anti-wrinkle according to claim 1 eye cream that compacts, is characterized in that, by withThe raw material of lower parts by weight is prepared from:
A phase: glycerine 3.8-4.2 part, hexylene glycol 0.55-0.65 part, hyaluronic acid 0.08-0.12Part, oat bran extract 4.8-5.2 part, PVM/MA decadiene crosslinked polymer0.45-0.55 part, water 58-62 part;
B phase: shea butter 3.8-4.2 part, dimethyl silicone polymer 0.8-1.2 part, sadTriglyceride DDD 3.8-4.2 part;
C phase: NaOH 0.12-0.13 part, water 0.9-1.1 part;
D phase: Sodium Polyacrylate 0.48-0.50 part, vitamin e acetate 0.38-0.42 part,Retinol Palmitate 0.08-0.12 part, Co-Q10 0.15-0.25 part;
E phase: D-pantothenyl aleohol 0.25-0.35 part, niacinamide 0.8-1.2 part;
F phase: ginkgo biloba extract 6-8 part, hanfangchin A 0.30-0.32 part, Phenoxyethanol0.28-0.30 part.
3. the anti-wrinkle according to claim 1 eye cream that compacts, is characterized in that, by withThe raw material of lower parts by weight is prepared from:
A phase: glycerine 3.9-4.0 part, hexylene glycol 0.58-0.60 part, hyaluronic acid 0.09-0.10Part, oat bran extract 5.0-5.1 part, PVM/MA decadiene crosslinked polymer0.58-0.50 part, water 59-60 part;
B phase: shea butter 3.9-4.1 part, dimethyl silicone polymer 0.9-1.0 part, sadTriglyceride DDD 3.9-4.0 part;
C phase: NaOH 0.12-0.13 part, water 0.9-1.1 part;
D phase: Sodium Polyacrylate 0.49-0.50 part, vitamin e acetate 0.39-0.41 part,Retinol Palmitate 0.09-0.11 part, Co-Q10 0.18-0.22 part;
E phase: D-pantothenyl aleohol 0.28-0.32 part, niacinamide 0.9-1.1 part;
F phase: ginkgo biloba extract 7-8 part, hanfangchin A 0.30-0.32 part, Phenoxyethanol0.29-0.30 part.
4. according to the eye cream that compacts of the anti-wrinkle described in claim 1-3 any one, its feature existsIn, described ginkgo biloba extract is prepared by the following method:
(a), more than ginkgo nut pulverizes 50 orders, the water that adds ginkgo nut 3-8 doubly to measure, in58-65 DEG C of lixiviate 55-65min, obtains mixture;
(b), add the alpha-amylase of the 1%-3% of described mixture weight, temperature raisesTo 75-83 DEG C, enzymolysis 55-65min;
(c), be cooled to 28-35 DEG C, adopt diatomite filtration, to obtain final product.
5. the anti-wrinkle according to claim 4 eye cream that compacts, is characterized in that, in stepSuddenly in (c), before described diatomite filtration, also comprise the step that adopts atlapulgite to filter;
The addition of described atlapulgite is the 25%-30% of water and ginkgo nut gross weight;
Described diatomaceous addition is the 15%-20% of water and ginkgo nut gross weight.
6. the anti-wrinkle according to claim 4 eye cream that compacts, is characterized in that, in stepSuddenly in (c), after described diatomite filtration, also comprise the step that adopts biologic active carbon filtration;
The addition of described biological activated carbon is the 7%-10% of water and ginkgo nut gross weight.
7. the anti-wrinkle according to claim 4 eye cream that compacts, is characterized in that, described inThe particle diameter of biological activated carbon is below 100 μ m; Described biological activated carbon is straw-stem active charcoal.
8. the preparation method of eye cream of compacting of the anti-wrinkle described in claim 1-7 any one, itsBe characterised in that, comprise the following steps:
By A heat phase, to 84-86 DEG C, insulation 28-35 minute, is then cooled to 48-52 DEG C,Add C phase, stir, obtain the mixture of A phase and C phase;
B heat phase, to 58-62 DEG C, is incubated to 8-15 minute;
B phase is mixed mutually with D, under stirring, is added in the mixture of A phase and C phase,Stir 8-15 minute;
Vacuum homogeneous 3-5 minute, then stir cooling in 8-15 minute, when temperature is 44-46 DEG C,Add E phase, vacuumize and stir 8-15 minute;
Be cooled to 38-42 DEG C, add F phase, vacuumize slow stirring 8-15 minute.
9. the anti-wrinkle according to claim 8 preparation method of eye cream of compacting, its featureBe, the rotating speed of stirring is 30-50r/min.
10. the anti-wrinkle according to claim 8 preparation method of eye cream of compacting, its featureBe, the rotating speed of described slow stirring is 10-20r/min.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106580813A (en) * | 2017-02-20 | 2017-04-26 | 侯马经济开发区金葵花大健康产业有限公司 | Total effect eye essence and preparation method thereof |
| CN108158945A (en) * | 2018-03-02 | 2018-06-15 | 贵州泛特尔细胞生物技术有限公司 | A kind of smoothing wrinkle essence breast |
| CN109875933A (en) * | 2019-03-28 | 2019-06-14 | 广州市富宝日用化工有限公司 | Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof |
| CN110431154A (en) * | 2017-01-26 | 2019-11-08 | 美容系统制药有限责任公司 | With the hyaluronic acid of natural or semi-synthetic cross-linking agents |
| CN111358715A (en) * | 2019-04-18 | 2020-07-03 | 吉林省东鳌鹿业科技开发有限公司 | Deer collagen polypeptide repair eye cream and preparation method thereof |
| CN111631977A (en) * | 2020-05-14 | 2020-09-08 | 福建快美健生物科技有限公司 | Children eye cream based on quinoa peptide and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101627956A (en) * | 2008-07-14 | 2010-01-20 | 孙海 | Method for preparing eye-care cosmetic |
| CN102247306A (en) * | 2010-05-18 | 2011-11-23 | 北京工商大学 | Oat extract and preparation method and utilization thereof |
| CN103191037A (en) * | 2013-03-30 | 2013-07-10 | 杭州师范大学 | Gingko whitening anti-acne cream |
| KR101360745B1 (en) * | 2012-09-28 | 2014-02-10 | 울산대학교 산학협력단 | Preparation method of ginkgo fermented liquor using heat tolerance amylase |
| CN104546630A (en) * | 2013-10-22 | 2015-04-29 | 罗鹏程 | Wrinkle-removing moisturizing efficient eye cream and preparation method thereof |
| CN105147590A (en) * | 2015-10-19 | 2015-12-16 | 广州科玛生物科技有限公司 | Anti-wrinkle eye cream and preparation method thereof |
-
2016
- 2016-01-29 CN CN201610066986.1A patent/CN105596262A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101627956A (en) * | 2008-07-14 | 2010-01-20 | 孙海 | Method for preparing eye-care cosmetic |
| CN102247306A (en) * | 2010-05-18 | 2011-11-23 | 北京工商大学 | Oat extract and preparation method and utilization thereof |
| KR101360745B1 (en) * | 2012-09-28 | 2014-02-10 | 울산대학교 산학협력단 | Preparation method of ginkgo fermented liquor using heat tolerance amylase |
| CN104718279A (en) * | 2012-09-28 | 2015-06-17 | 蔚山大学校产学协力团 | Method for preparing fermented ginkgo biloba beverage using heat-resistant amylase |
| US20150259635A1 (en) * | 2012-09-28 | 2015-09-17 | University Of Ulsan Foundation For Industry Cooperation | Method for preparing fermented ginkgo biloba beverage using heat-resistant amylase |
| CN103191037A (en) * | 2013-03-30 | 2013-07-10 | 杭州师范大学 | Gingko whitening anti-acne cream |
| CN104546630A (en) * | 2013-10-22 | 2015-04-29 | 罗鹏程 | Wrinkle-removing moisturizing efficient eye cream and preparation method thereof |
| CN105147590A (en) * | 2015-10-19 | 2015-12-16 | 广州科玛生物科技有限公司 | Anti-wrinkle eye cream and preparation method thereof |
Non-Patent Citations (6)
| Title |
|---|
| 刘德军: "《现代中药化妆品制作工艺及配方》", 31 May 2009, 化学工业出版社 * |
| 宋丽雅等: "《化妆品植物功效添加剂的研究与开发》", 30 September 2011, 中国轻工业出版社 * |
| 王方等: "《现代离子交换与吸附技术》", 30 November 2015, 清华大学出版社 * |
| 祝钧等: "《化妆品植物学》", 31 July 2009, 中国农业大学出版社 * |
| 赵黎明等: "《食品工程原理》", 30 September 2013, 中国纺织出版社 * |
| 马世宏: "银杏在化妆品中的引用", 《中国野生植物资源》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110431154A (en) * | 2017-01-26 | 2019-11-08 | 美容系统制药有限责任公司 | With the hyaluronic acid of natural or semi-synthetic cross-linking agents |
| CN110431154B (en) * | 2017-01-26 | 2022-07-05 | 美容系统制药有限责任公司 | Hyaluronic acid cross-linked with natural or semi-synthetic cross-linking agents |
| CN106580813A (en) * | 2017-02-20 | 2017-04-26 | 侯马经济开发区金葵花大健康产业有限公司 | Total effect eye essence and preparation method thereof |
| CN108158945A (en) * | 2018-03-02 | 2018-06-15 | 贵州泛特尔细胞生物技术有限公司 | A kind of smoothing wrinkle essence breast |
| CN109875933A (en) * | 2019-03-28 | 2019-06-14 | 广州市富宝日用化工有限公司 | Compact eye cream cosmetics of a kind of U.S. pupil and preparation method thereof |
| CN111358715A (en) * | 2019-04-18 | 2020-07-03 | 吉林省东鳌鹿业科技开发有限公司 | Deer collagen polypeptide repair eye cream and preparation method thereof |
| CN111631977A (en) * | 2020-05-14 | 2020-09-08 | 福建快美健生物科技有限公司 | Children eye cream based on quinoa peptide and preparation method thereof |
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Application publication date: 20160525 |