CN105560166A - Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel - Google Patents
Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel Download PDFInfo
- Publication number
- CN105560166A CN105560166A CN201510839986.6A CN201510839986A CN105560166A CN 105560166 A CN105560166 A CN 105560166A CN 201510839986 A CN201510839986 A CN 201510839986A CN 105560166 A CN105560166 A CN 105560166A
- Authority
- CN
- China
- Prior art keywords
- gel
- silver ion
- purified water
- antibacterial gel
- gynecological external
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to the field of technologies for preparing medicines, in particular to gynecological external antibacterial gel with silver ions and a method for preparing the gynecological external antibacterial gel. The gynecological external antibacterial gel comprises 0.6-1 g of efficient active silver ion solution, 5-6 g of 940-type carbomer, 1.6-2 g of edible sodium hydroxide, 100-120 g of glycerin, 15-20 g of menthol, 1-2 g of ethylparaben, an appropriate quantity of ethyl alcohol and 1000 g of purified water. The gynecological external antibacterial gel and the method have the advantages that gynecological external antibacterial gel products prepared by the aid of the method are uniform; appearance characteristics, a pH (potential of hydrogen) value and silver contents of the gynecological external antibacterial gel prepared by the aid of the method do not change obviously under high-temperature, low-temperature and intense-light conditions, and accordingly the quality of gel preparations are stable and controllable.
Description
Technical field
The present invention relates to medicine preparing technical field, be specifically related to a kind of silver ion gynaecological externally used antimicrobial gel and preparation method thereof.
Background technology
Silver is just used to accelerating wound healing since ancient times, treatment is infected, purified waste water and preserve beverage, the infection that science application silvery agent anti Bacillus pyocyaneu Flugge and staphylococcus aureus cause resulted from for 19th century, until people just really find that silver is a kind of broad-spectrum antiseptic material after 20th century.Silver ion disinfectant is a kind of nontoxic, tasteless, non-stimulated, free of contamination " green bactericide product ", is a kind of non-antibiotic class broad-spectrum antiseptic material.In recent years, silver-ion antibiotic material pref is because of its excellent anti-bacteriostasis property and safety non-toxic, the characteristic not producing drug resistance, and the application in sterilization and infection more and more comes into one's own, and demonstrates wide application prospect.At present, ratify containing the listing of silver products as medical device product acquisition U.S. FDA for external existing tens kinds, domestic existing more than 70 silver-ion antibiotic product obtains the approval registration of relevant provincial food Drug Administration as two class medical apparatus and instruments, comprises silver ion gel, silver-colored dressing etc.
Summary of the invention
The present invention is intended to propose a kind of silver ion gynaecological externally used antimicrobial gel and preparation method thereof.
Technical program of the present invention lies in:
Silver ion gynaecological externally used antimicrobial gel and preparation method thereof, consists of the following composition: high-efficiency activated silver ion solution 0.6-1g, Acritamer 940 type 5-6g, edible sodium hydroxide 1.6-2g, glycerol 100-120g, Mentholum 15-20g, ethyl hydroxybenzoate 1-2g, appropriate amount of ethanol, purified water 1000g.
The preparation method of silver ion gynaecological externally used antimicrobial gel, comprises the following steps:
(1) 5g Acritamer 940 is evenly sprinkling upon in 1000g purified water, soaks, place 12h and make it fully swelling and stir;
(2) 1.6-2g being eaten sodium hydroxide is dissolved in purified water, stirring and emulsifying, and adjust ph is ph=8, obtains carbomer gel substrate;
(3) dilute high-efficiency activated silver ion solution by purified water, and add in gel-type vehicle, limit edged stirs;
(4) add glycerol, Mentholum, limit edged stirs, and makes mix homogeneously;
(5) add after ethyl hydroxybenzoate dissolve with ethanol, and add purified water mix homogeneously;
(6) by the fill of silver ion gynaecological externally used antimicrobial gel at disposable vaginal in gel device.
Stir in described (1) and use automatic vacuum homogenizer to carry out emulsifying stirring.
Technique effect of the present invention is:
The silver ion gynaecological externally used antimicrobial gel products prepared by method provided by the invention is even; Under high temperature, low temperature, intense light conditions, gel appearance character, pH value, silver content without significant change, gel preparation stable and controllable for quality.
Detailed description of the invention
Silver ion gynaecological externally used antimicrobial gel and preparation method thereof, consists of the following composition: high-efficiency activated silver ion solution 0.6-1g, Acritamer 940 type 5-6g, edible sodium hydroxide 1.6-2g, glycerol 100-120g, Mentholum 15-20g, ethyl hydroxybenzoate 1-2g, appropriate amount of ethanol, purified water 1000g.
The preparation method of silver ion gynaecological externally used antimicrobial gel, comprises the following steps:
(1) 5g Acritamer 940 is evenly sprinkling upon in 1000g purified water, soaks, place 12h and make it fully swelling and stir;
(2) 1.6-2g being eaten sodium hydroxide is dissolved in purified water, stirring and emulsifying, and adjust ph is ph=8, obtains carbomer gel substrate;
(3) dilute high-efficiency activated silver ion solution by purified water, and add in gel-type vehicle, limit edged stirs;
(4) add glycerol, Mentholum, limit edged stirs, and makes mix homogeneously;
(5) add after ethyl hydroxybenzoate dissolve with ethanol, and add purified water mix homogeneously;
(6) by the fill of silver ion gynaecological externally used antimicrobial gel at disposable vaginal in gel device.
Stir in described (1) and use automatic vacuum homogenizer to carry out emulsifying stirring.
Claims (3)
1. silver ion gynaecological externally used antimicrobial gel and preparation method thereof, it is characterized in that: consist of the following composition: high-efficiency activated silver ion solution 0.6-1g, Acritamer 940 type 5-6g, edible sodium hydroxide 1.6-2g, glycerol 100-120g, Mentholum 15-20g, ethyl hydroxybenzoate 1-2g, appropriate amount of ethanol, purified water 1000g.
2. the preparation method of silver ion gynaecological externally used antimicrobial gel as claimed in claim 1, is characterized in that: comprise the following steps:
(1) 5g Acritamer 940 is evenly sprinkling upon in 1000g purified water, soaks, place 12h and make it fully swelling and stir;
(2) 1.6-2g being eaten sodium hydroxide is dissolved in purified water, stirring and emulsifying, and adjust ph is ph=8, obtains carbomer gel substrate;
(3) dilute high-efficiency activated silver ion solution by purified water, and add in gel-type vehicle, limit edged stirs;
(4) add glycerol, Mentholum, limit edged stirs, and makes mix homogeneously;
(5) add after ethyl hydroxybenzoate dissolve with ethanol, and add purified water mix homogeneously;
(6) by the fill of silver ion gynaecological externally used antimicrobial gel at disposable vaginal in gel device.
3. the preparation method of silver ion gynaecological externally used antimicrobial gel as claimed in claim 2, is characterized in that: stir in described (1) and use automatic vacuum homogenizer to carry out emulsifying stirring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510839986.6A CN105560166A (en) | 2015-11-27 | 2015-11-27 | Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510839986.6A CN105560166A (en) | 2015-11-27 | 2015-11-27 | Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105560166A true CN105560166A (en) | 2016-05-11 |
Family
ID=55871194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510839986.6A Pending CN105560166A (en) | 2015-11-27 | 2015-11-27 | Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105560166A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106833361A (en) * | 2017-02-23 | 2017-06-13 | 广州优瑞塑料有限公司 | A kind of antibacterial aqueous polyurethane coating glue of silver ion deodorizing |
| CN114224914A (en) * | 2021-11-10 | 2022-03-25 | 惠州华阳医疗器械有限公司 | Antimicrobial composition and preparation method thereof |
| CN116808223A (en) * | 2023-08-04 | 2023-09-29 | 复旦大学附属中山医院 | Application of pyruvate kinase M2 activator in preparation of medicine for treating psoriasis |
-
2015
- 2015-11-27 CN CN201510839986.6A patent/CN105560166A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106833361A (en) * | 2017-02-23 | 2017-06-13 | 广州优瑞塑料有限公司 | A kind of antibacterial aqueous polyurethane coating glue of silver ion deodorizing |
| CN114224914A (en) * | 2021-11-10 | 2022-03-25 | 惠州华阳医疗器械有限公司 | Antimicrobial composition and preparation method thereof |
| CN116808223A (en) * | 2023-08-04 | 2023-09-29 | 复旦大学附属中山医院 | Application of pyruvate kinase M2 activator in preparation of medicine for treating psoriasis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104257639B (en) | A kind of liniment for Wound treating and preparation method thereof | |
| CN105169408B (en) | A kind of sodium alginate antimicrobial spray and preparation method thereof | |
| CN110064070A (en) | Containing organic quaternary ammonium salt or with silane end organic quaternary ammonium salt anti-bacterial hydrogel and preparation method thereof | |
| CN105560166A (en) | Gynecological external antibacterial gel with silver ions and method for preparing gynecological external antibacterial gel | |
| CN108096226B (en) | Oral ulcer film containing polylysine and preparation method thereof | |
| CN112370568A (en) | Liquid dressing and preparation method thereof | |
| CN103446294B (en) | Murrayae folium ET Cacumen extract preparation method, Murrayae folium ET Cacumen extract obtained thereby and application thereof | |
| CN104740141B (en) | A kind of antimicrobial spray and preparation method thereof | |
| CN100396290C (en) | External use anti-bacteria foaming agent for gynecology | |
| CN103550254B (en) | Breathable itching-relieving antisepsis scar treating paster and preparation method thereof | |
| CN109432201B (en) | Gynecological antibacterial gel and preparation method thereof | |
| CN102526121B (en) | Wound repair composition and preparation method and application thereof | |
| CN110404009A (en) | A kind of antibacterial gel preparation and its preparation method and application | |
| CN103768089A (en) | Chitosan antibacterial lotion for gynecology and preparation method thereof | |
| CN114652767A (en) | Medicated bath agent for nipples of dairy cows and preparation method thereof | |
| CN108066278B (en) | Gynecological gel containing chitosan oligosaccharide and preparation method thereof | |
| CN104922151A (en) | Externally applied hydrogel preparation for women and preparing method thereof | |
| CN102697786A (en) | Urotropine composite skin disinfectant and preparation method thereof | |
| CN106237373A (en) | A kind of preparation method of the based composite dressing for medical use containing nanometer silver | |
| CN104910404A (en) | Chitosan-glycerol-nano silver sponge as well as preparation method and application of chitosan-glycerol-nano silver sponge | |
| CN110604755A (en) | Antibacterial and anti-inflammatory composition and preparation method and application thereof | |
| CN103948607A (en) | Germicidal and bacteriostatic chilblain cream | |
| CN102579487A (en) | Pharmaceutical composition having abirritation, anti-inflammation and antibacterium | |
| CN103860600A (en) | Chitosan iodine honey temperature-sensitive gel for treating dental ulcer and preparation method of gel | |
| CN102885850B (en) | Porous gel granules for treating vaginitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160511 |
|
| WD01 | Invention patent application deemed withdrawn after publication |