CN105535053A - Preparation method of radix ginseng rubra paste - Google Patents

Preparation method of radix ginseng rubra paste Download PDF

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CN105535053A
CN105535053A CN201610020789.6A CN201610020789A CN105535053A CN 105535053 A CN105535053 A CN 105535053A CN 201610020789 A CN201610020789 A CN 201610020789A CN 105535053 A CN105535053 A CN 105535053A
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alcohol
radix ginseng
extraction
steam
extract
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CN105535053B (en
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窦建鹏
梁清
张劲松
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Changchun Xinye Biotechnology Co.,Ltd.
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Jilin University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention provides a preparation method of a radix ginseng rubra paste. The radix ginseng rubra paste is directly prepared from fresh ginseng or sun-dried ginseng, the step of preparing radix ginseng rubra first is avoided, the process is simple, cost is low, the energy consumption is low, the production period is shortened by 50% or above, and the preparation method is suitable for large-scale production. The heating time in the preparation process is short, the Maillard browning degree is low, and the product is good in color and luster, strong in flavor and good in water solubility. Extract extracted with alcohol is steamed, ginsenoside can be sufficiently converted, and water-soluble components in the extract are dissolved out and added to aqueous extract of ginseng. On the dry basis, the total saponin content of the radix ginseng rubra paste prepared from sun-dried ginseng is 3.2-3.4%, the total saponin content of the radix ginseng rubra paste prepared from fresh ginseng is 3.5-3.9%, and the total saponin content of an existing radix ginseng rubra paste is lower than 2.5%. The total saponin content of the radix ginseng rubra paste prepared from sun-dried ginseng is increased by 28-36%, and the total saponin content of the radix ginseng rubra paste prepared from fresh ginseng is increased by 40-56%. The content of ginsenoside monomer Rh1 is 0.17-0.45 mg/g, the content of Rh2 is 0.01-0.09 mg/g, the content of Rg3 is 0.56-1.60 mg/g, and the content of Rg5 is 0.41-0.95 mg/g.

Description

A kind of preparation method of Radix Ginseng Rubra cream
Technical field
The present invention relates to a kind of preparation method of Radix Ginseng Rubra cream, belong to Radix Ginseng Rubra cream processing technique field.
Background technology
Radix Ginseng belongs to the plant of Araliaceae (Araliaceae) Panax.Radix Ginseng Rubra refers to fresh ginseng to be raw material, through the Ginseng Products scrubbed, steam, drying prepares, wherein to steam and drying is the important step of red ginseng processing, steam and have decisive influence with temperature and time time dry to Radix Ginseng Rubra quality, can be there is chemical conversion and the Maillaid braun reaction of ginsenoside in Radix Ginseng Rubra, thus produce the rare ginsenoside Rg do not had in fresh ginseng in the course of processing 3, Rg 5, Rh 1, Rh 2deng composition and complicated brown stain product.After fresh ginseng is processed into Radix Ginseng Rubra, is more suitable for elderly and infirm and takes, Radix Ginseng Rubra is insufficiency of vital energy and blood and the tonification good merchantable brand of partially yang deficiency person, can health invigorating, improves immunity of organisms.
Radix Ginseng Rubra cream refers to have good water solublity by the Radix Ginseng Rubra extractum that Radix Ginseng Rubra is made after by water extraction, filtration, the technique such as concentrated.Existing Radix Ginseng Rubra cream is all adopt this kind of method to process.The process-cycle of Radix Ginseng Rubra is longer, generally needs 5-7 days, steaming and the dry energy needing consumption more of Radix Ginseng Rubra, and then red ginseng processing is become Radix Ginseng Rubra cream, and also want further consumes energy, energy consumption is high, and production cost is just high.Because Radix Ginseng Rubra cream is in the course of processing, through being repeatedly subject to thermal work steps for a long time, not only easily destroy the structure of ginsenoside, cause the principle active component total Ginsenosides Content of Radix Ginseng Rubra cream lower, and Radix Ginseng Rubra cream color and luster can be caused to turn black, have penetrating odor, reduce the organoleptic indicator of product.
Summary of the invention
Object of the present invention is exactly that to provide a kind of for above-mentioned deficiency be raw material with fresh ginseng, directly prepares the method for Radix Ginseng Rubra cream.
The preparation method of a kind of Radix Ginseng Rubra cream provided by the invention, its step and condition as follows:
One, the raw material Radix Ginseng used is as follows: fresh ginseng or Radix Ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction:
Ginseng raw material pulverized, put into extraction pot and extract, 80-95% alcohol heat reflux extracts 0.5-2h, and alcohol adding amount is 3-8 times of fresh ginseng gross mass, or alcohol adding amount is 5-10 times of Radix Ginseng gross mass, extraction time 1-3 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam:
Alcohol-extracted extract being placed in steaming ginseng cabinet utilizes high-temperature steam to steam, and keeps 110-130 DEG C and steams 0.5-4h, be cooled to room temperature after steaming;
(3) dissolve:
By the alcohol-extracted extract 10-50 times water dissolution steamed in (2), filter to get filtrate;
(4) water extraction:
By the Radix Ginseng residue after alcohol extraction in (1), put into extraction pot and extract, circumfluence distillation 1-3h, amount of water be the 5-10 of Radix Ginseng gross mass doubly, extraction time 1-3 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure:
(3) the filtrate and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
Beneficial effect: the preparation method of a kind of Radix Ginseng Rubra cream provided by the invention, because adopt fresh ginseng or Radix Ginseng directly to prepare Radix Ginseng Rubra cream, avoids the step first preparing Radix Ginseng Rubra, technique is simple, and cost is low, and energy consumption is low, production cycle shortens more than 50%, is applicable to large-scale production.In preparation process, heat time heating time is short, and Mei Lade browning degree is light, and product color is good, strong flavor, good water solubility.Alcohol-extracted extract is carried out steaming processing, can make ginsenoside that sufficient conversion occurs, wherein water soluble ingredient is dissolved out joins in the water extract of Radix Ginseng, with the amount of giving money as a gift note, add total saponin content in obtained Radix Ginseng Rubra cream product.Wherein, the Radix Ginseng Rubra cream total saponin content that Radix Ginseng obtains is 3.2-3.4%, remember with the amount of giving money as a gift, the Radix Ginseng Rubra cream total saponin content that fresh ginseng obtains is 3.5-3.9%, with the amount of giving money as a gift note, the total saponin content testing result of Radix Ginseng Rubra cream product is sold lower than 2.5% in existing market, remembers with the amount of giving money as a gift, the Radix Ginseng Rubra cream total saponin content that the present invention's Radix Ginseng obtains exceeds 28-36%, and the Radix Ginseng Rubra cream total saponin content that fresh ginseng obtains exceeds 40-56%.Ginsenoside monomer Rh in Radix Ginseng Rubra cream prepared by the present invention 1content be 0.17-0.45mg/g, Rh 2content be 0.01-0.09mg/g, Rg 3content be 0.56-1.60mg/g, Rg 5content be 0.41-0.95mg/g.
Detailed description of the invention
Embodiment 1
One, the raw material Radix Ginseng used is as follows: fresh ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 80% alcohol heat reflux extracts 2h, and alcohol adding amount is 8 times of fresh ginseng gross mass, extraction time 1 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 110 DEG C and steam 4h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 10 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 3h, amount of water is 10 times of Radix Ginseng gross mass, extraction time 1 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure:
(3) the filtrate and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
The Radix Ginseng Rubra cream utilizing this technique to prepare is vivid bronzing, and abnormal smells from the patient is natural, strong, and with the amount of giving money as a gift note, total saponin content is 3.5%.Ginsenoside monomer content is in table 1.
Embodiment 2
One, the raw material Radix Ginseng used is as follows: fresh ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 90% alcohol heat reflux extracts 1h, and alcohol adding amount is 6 times of fresh ginseng gross mass, extraction time 2 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 120 DEG C and steam 1h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 30 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 2h, amount of water is 8 times of Radix Ginseng gross mass, extraction time 2 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
The Radix Ginseng Rubra cream utilizing this technique to prepare is vivid bronzing, and abnormal smells from the patient is natural, strong, and with the amount of giving money as a gift note, total saponin content is 3.6%.Ginsenoside monomer content is in table 1.
Embodiment 3
One, the raw material Radix Ginseng used is as follows: fresh ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 95% alcohol heat reflux extracts 0.5h, and alcohol adding amount is 3 times of fresh ginseng gross mass, extraction time 3 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 130 DEG C and steam 0.5h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 50 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 1h, amount of water is 5 times of Radix Ginseng gross mass, extraction time 3 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
The Radix Ginseng Rubra cream utilizing this technique to prepare is vivid bronzing, and abnormal smells from the patient is natural, strong, and with the amount of giving money as a gift note, total saponin content is 3.9%.Ginsenoside monomer content is in table 1.
Embodiment 4
One, the raw material Radix Ginseng used is as follows: Radix Ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction: Radix Ginseng is pulverized, puts into extraction pot and extract, 80% alcohol heat reflux extracts 2h, and alcohol adding amount is 10 times of Radix Ginseng gross mass, extraction time 1 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 110 DEG C and steam 4h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 10 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 3h, amount of water is 10 times of Radix Ginseng gross mass, extraction time 1 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure:
(3) the filtrate and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
The Radix Ginseng Rubra cream utilizing this technique to prepare is vivid bronzing, and abnormal smells from the patient is natural, strong, and with the amount of giving money as a gift note, total saponin content is 3.2%.Ginsenoside monomer content is in table 1.
Embodiment 5
One, the raw material Radix Ginseng used is as follows: Radix Ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction: Radix Ginseng is pulverized, puts into extraction pot and extract, 95% alcohol heat reflux extracts 0.5h, and alcohol adding amount is 5 times of Radix Ginseng gross mass, extraction time 3 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 130 DEG C and steam 0.5h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 50 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 1h, amount of water is 5 times of Radix Ginseng gross mass, extraction time 3 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
The Radix Ginseng Rubra cream utilizing this technique to prepare is vivid bronzing, and abnormal smells from the patient is natural, strong, and with the amount of giving money as a gift note, total saponin content is 3.4%.Ginsenoside monomer content is in table 1.
In the Radix Ginseng Rubra cream that table 1 is prepared for the present invention, ginsenoside monomer is containing scale.As can be seen from Table 1, ginsenoside monomer Rh in the Radix Ginseng Rubra cream prepared of the present invention 1content be 0.17-0.45mg/g, Rh 2content be 0.01-0.09mg/g, Rg 3content be 0.56-1.60mg/g, Rg 5content be 0.41-0.95mg/g.

Claims (6)

1. a preparation method for Radix Ginseng Rubra cream, is characterized in that, its step and condition as follows:
One, the raw material Radix Ginseng used is as follows: fresh ginseng or Radix Ginseng;
Two, preparation step and condition as follows:
(1) alcohol extraction:
Ginseng raw material pulverized, put into extraction pot and extract, 80-95% alcohol heat reflux extracts 0.5-2h, and alcohol adding amount is 3-8 times of fresh ginseng gross mass, or alcohol adding amount is 5-10 times of Radix Ginseng gross mass, extraction time 1-3 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam:
Alcohol-extracted extract being placed in steaming ginseng cabinet utilizes high-temperature steam to steam, and keeps 110-130 DEG C and steams 0.5-4h, be cooled to room temperature after steaming;
(3) dissolve:
By the alcohol-extracted extract 10-50 times water dissolution steamed in (2), filter to get filtrate;
(4) water extraction:
By the Radix Ginseng residue after alcohol extraction in (1), put into extraction pot and extract, circumfluence distillation 1-3h, amount of water be the 5-10 of Radix Ginseng gross mass doubly, extraction time 1-3 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure:
(3) the filtrate and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
2. the preparation method of a kind of Radix Ginseng Rubra cream as claimed in claim 1, is characterized in that, its step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 80% alcohol heat reflux extracts 2h, and alcohol adding amount is 8 times of fresh ginseng gross mass, extraction time 1 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 110 DEG C and steam 4h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 10 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 3h, amount of water is 10 times of Radix Ginseng gross mass, extraction time 1 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
3. the preparation method of a kind of Radix Ginseng Rubra cream as claimed in claim 1, is characterized in that, its step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 90% alcohol heat reflux extracts 1h, and alcohol adding amount is 6 times of fresh ginseng gross mass, extraction time 2 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 120 DEG C and steam 1h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 30 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 2h, amount of water is 8 times of Radix Ginseng gross mass, extraction time 2 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
4. the preparation method of a kind of Radix Ginseng Rubra cream as claimed in claim 1, is characterized in that, its step and condition as follows:
(1) alcohol extraction: fresh ginseng is pulverized, puts into extraction pot and extract, 95% alcohol heat reflux extracts 0.5h, and alcohol adding amount is 3 times of fresh ginseng gross mass, extraction time 3 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 130 DEG C and steam 0.5h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 50 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 1h, amount of water is 5 times of Radix Ginseng gross mass, extraction time 3 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
5. the preparation method of a kind of Radix Ginseng Rubra cream as claimed in claim 1, is characterized in that, its step and condition as follows:
(1) alcohol extraction: Radix Ginseng is pulverized, puts into extraction pot and extract, 80% alcohol heat reflux extracts 2h, and alcohol adding amount is 10 times of Radix Ginseng gross mass, extraction time 1 time; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 110 DEG C and steam 4h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 10 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 3h, amount of water is 10 times of Radix Ginseng gross mass, extraction time 1 time; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure:
(3) the filtrate and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
6. the preparation method of a kind of Radix Ginseng Rubra cream as claimed in claim 1, is characterized in that, its step and condition as follows:
(1) alcohol extraction: Radix Ginseng is pulverized, puts into extraction pot and extract, 95% alcohol heat reflux extracts 0.5h, and alcohol adding amount is 5 times of Radix Ginseng gross mass, extraction time 3 times; Merged by extracting solution, filter, concentrating under reduced pressure reclaims ethanol, obtains alcohol-extracted extract;
(2) steam: alcohol-extracted extract is placed in steaming ginseng cabinet and utilizes high-temperature steam to steam, keep 130 DEG C and steam 0.5h, after steaming, be cooled to room temperature;
(3) dissolve: by the alcohol-extracted extract 50 times of water dissolutioies steamed in (2), filter to get filtrate;
(4) water extraction: incite somebody to action Radix Ginseng residue (1), put into extraction pot and extract, circumfluence distillation 1h, amount of water is 5 times of Radix Ginseng gross mass, extraction time 3 times; Extracting solution is merged, filters to get filtrate;
(5) concentrating under reduced pressure: the filtrate (3) and (4) obtained is merged, is evaporated to moisture content≤40%, is cooled to room temperature, obtain Radix Ginseng Rubra cream.
CN201610020789.6A 2016-01-14 2016-01-14 A kind of preparation method of red ginseng cream Active CN105535053B (en)

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