CN105534818B - 一种儿茶素漱口水及其制备方法 - Google Patents

一种儿茶素漱口水及其制备方法 Download PDF

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CN105534818B
CN105534818B CN201610040345.9A CN201610040345A CN105534818B CN 105534818 B CN105534818 B CN 105534818B CN 201610040345 A CN201610040345 A CN 201610040345A CN 105534818 B CN105534818 B CN 105534818B
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童华荣
岳翠男
王治会
毛世红
陆昌琪
褚飞扬
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Southwest University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • A61K8/21Fluorides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives

Abstract

本发明公开了一种儿茶素漱口水及其制备方法,漱口水的原料包括儿茶素,金盏菊,玫瑰茄,胎菊,薄荷,乙醇,氨基酸,表面活化剂,氟化钠,防腐剂和水。制备步骤为:将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为80‑90℃,冲泡时间3‑5min,出汤后冷却,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、氟化钠和防腐剂,用水加至100%,混匀即可。本发明通过对儿茶素、金盏菊、玫瑰茄、胎菊、薄荷、乙醇、氨基酸进行有机组合,并确定各组分的最佳用量搭配,不仅起到清新口腔的作用,还能够从根本上去除口臭,对口腔起到保健功效,并且本发明所述漱口水成分天然,不含香精,对人体没有副作用。

Description

一种儿茶素漱口水及其制备方法
技术领域
本发明涉及一种漱口水,尤其涉及一种儿茶素漱口水及其制备方法。
背景技术
目前国内外有很多漱口水出现,这些漱口水的主要原料一般是各种物质的浓缩汁,或添加了中药。另外,国外的很多漱口水里面还添加了大量的化学合成物质,对人类的身体有很大影响,甚至会引发人的身体过敏症状。更为重要的是,漱口水使用过后没有对各种口腔问题起到明显改善的作用,仅仅是使口腔残留漱口水的香味而已,口腔内部的细菌、口臭等问题并没有得到解决。
发明内容
有鉴于此,本发明的目的在于提供一种儿茶素漱口水及其制备方法,根据本发明所述配方获得的漱口水具有更好的除口臭作用,能有效改善口腔问题。
本发明采取的技术方案如下:
1、一种儿茶素漱口水的制备方法,原料按重量百分比计,由以下组分组成:儿茶素0.3-0.8%,金盏菊2-5%,玫瑰茄2-4%,胎菊5-8%,薄荷2-5%,乙醇0.5-1.5%,氨基酸0.05-0.1%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水;具体步骤为:将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为80-90℃,冲泡时间3-5min,出汤后冷却,过滤,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、氟化钠和防腐剂,用水加至100%,混匀即可。
优选的,原料按重量百分比计,由以下组分组成:儿茶素0.5%,金盏菊3%,玫瑰茄3%,胎菊5%,薄荷4%,乙醇0.5%,氨基酸0.1%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。
优选的,原料按重量百分比计,由以下组分组成:儿茶素0.3%,金盏菊4%,玫瑰茄2%,胎菊8%,薄荷2%,乙醇0.5%,氨基酸0.05%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。
优选的,原料按重量百分比计,由以下组分组成:儿茶素0.8%,金盏菊5%,玫瑰茄2%,胎菊8%,薄荷5%,乙醇1.5%,氨基酸0.06%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。
优选的,所述表面活性剂为吐温-20。
2、上述制备方法获得的儿茶素漱口水。
本发明的有益效果在于:儿茶素可以预防蛀牙、缓解牙周病与牙菌斑,对甲硫醇等物质引发的口臭具有明显清除作用,尤其对经常抽烟的人群具有更有益的效果,另外儿茶素的抗菌、杀菌功效非常显著。金盏菊同样具有消炎抗菌、清热降火的作用,玫瑰茄、胎菊清凉解毒,薄荷疏风散热。乙醇作为溶剂能够提高漱口水中有效物质的溶解度和含量,提高漱口水的通透性,还具有防冻、收敛、杀菌的作用。虽然现有漱口水中也添加有乙醇,但由于其乙醇量添加过多,致使口腔中的菌落发生改变,不利于人体健康,因此,本发明通过实验设计有效降低了漱口水中乙醇的用量,使口腔的微生态环境保持平衡。而氨基酸作为一种具有鲜爽味的物质可替代香精,有助于补充口腔肌肉活力、并且对解除口腔毒素有很大的贡献。本发明通过对儿茶素、金盏菊、玫瑰茄、胎菊、薄荷、乙醇、氨基酸进行有机组合,并确定各组分的最佳用量搭配,不仅起到清新口腔的作用,还能够从根本上去除口臭,对口腔起到保健功效,并且本发明所述漱口水成分天然,不含香精,对人体没有副作用。
具体实施方式
下面对本发明的优选实施例进行详细的描述。实施例中未注明具体条件的实验方法,通常按照常规条件或按照制造厂商所建议的条件。
实施例1
一种儿茶素漱口水的制备方法,原料按重量百分比计,由以下组分组成:儿茶素0.5%,金盏菊3%,玫瑰茄3%,胎菊5%,薄荷4%,乙醇0.5%,氨基酸0.1%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为80℃,冲泡时间5min,出汤后冷却,过滤,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、氟化钠和防腐剂,用水加至100%,边调和边震荡,之后静止半个小时即可。
实施例2
一种儿茶素漱口水的制备方法,原料按重量百分比计,由以下组分组成:儿茶素0.3%,金盏菊4%,玫瑰茄2%,胎菊8%,薄荷2%,乙醇0.5%,氨基酸0.05%,吐温-200.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为90℃,冲泡时间4min,出汤后冷却,过滤,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、氟化钠和防腐剂,用水加至100%,边调和边震荡,之后静止半个小时即可。
实施例3
一种儿茶素漱口水的制备方法,原料按重量百分比计,由以下组分组成:儿茶素0.8%,金盏菊5%,玫瑰茄2%,胎菊8%,薄荷5%,乙醇1.5%,氨基酸0.06%,吐温-200.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为88℃,冲泡时间4min,出汤后冷却,过滤,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、氟化钠和防腐剂,用水加至100%,边调和边震荡,之后静止半个小时即可。
实施例4-10与实施例1-3类似,不同的是儿茶素、金盏菊、玫瑰茄、胎菊、薄荷、乙醇以及氨基酸的用量,其具体用量见表1。
表1各实施例配方的漱口水消费者的接受度评价表
接受度的评价方式如下:
将接受性尺度依次划分为:“5 4 3 2 1 0 -1 -2 -3 -4 -5”11个等级,5为极喜欢,-5为极不喜欢,从5到-5接受性逐渐降低。
通过实验对比,最终确定儿茶素漱口水的优选配方按重量百分比计,为儿茶素0.3-0.8%,金盏菊2-5%,玫瑰茄2-4%,胎菊5-8%,薄荷2-5%,乙醇0.5-1.5%,氨基酸0.05-0.1%,表面活化剂0.05%,氟化钠(牙膏级)0.05%,防腐剂0.01%,余量为水。
将实施例1-3这三个优选配方进行进一步感官评价,结果见表2。
表2优选的三个实施例的强度评价数据
表2是100个消费者评价的综合评分,用0-15的强度尺度表达感觉到的强度,从0到15强度依次递增,0为感觉不到,15为极强。根据消费者们感受到的漱口水的滋味、香气与效果强度,然后结合消费者们的接受性强度,获得效果最佳的三个漱口水配方。结果显示,消费者对于实施例1-3所述优选配方的接受度均较好,本发明所述儿茶素漱口水具有一定的市场前景。
最后说明的是,以上优选实施例仅用以说明本发明的技术方案而非限制,尽管通过上述优选实施例已经对本发明进行了详细的描述,但本领域技术人员应当理解,可以在形式上和细节上对其作出各种各样的改变,而不偏离本发明权利要求书所限定的范围。

Claims (6)

1.一种儿茶素漱口水的制备方法,其特征在于,原料按重量百分比计,由以下组分组成:儿茶素0.3-0.8%,金盏菊2-5%,玫瑰茄2-4%,胎菊5-8%,薄荷2-5%,乙醇0.5-1.5%,氨基酸0.05-0.1%,表面活性剂0.05%,牙膏级氟化钠0.05%,防腐剂0.01%,余量为水;具体步骤为:将配比量的金盏菊、玫瑰茄、胎菊、薄荷分别用水进行冲泡,水温为80-90℃,冲泡时间3-5min,出汤后冷却,过滤,获得茶汤;将茶汤混合,加入配比量的儿茶素、乙醇、氨基酸、表面活性剂、牙膏级氟化钠和防腐剂,用水加至100%,混匀即可。
2.根据权利要求1所述的一种儿茶素漱口水的制备方法,其特征在于,原料按重量百分比计,由以下组分组成:儿茶素0.5%,金盏菊3%,玫瑰茄3%,胎菊5%,薄荷4%,乙醇0.5%,氨基酸0.1%,表面活性剂0.05%,牙膏级氟化钠0.05%,防腐剂0.01%,余量为水。
3.根据权利要求1所述的一种儿茶素漱口水的制备方法,其特征在于,原料按重量百分比计,由以下组分组成:儿茶素0.3%,金盏菊4%,玫瑰茄2%,胎菊8%,薄荷2%,乙醇0.5%,氨基酸0.05%,表面活性剂0.05%,牙膏级氟化钠0.05%,防腐剂0.01%,余量为水。
4.根据权利要求1所述的一种儿茶素漱口水的制备方法,其特征在于,原料按重量百分比计,由以下组分组成:儿茶素0.8%,金盏菊5%,玫瑰茄2%,胎菊8%,薄荷5%,乙醇1.5%,氨基酸0.06%,表面活性剂0.05%,牙膏级氟化钠0.05%,防腐剂0.01%,余量为水。
5.根据权利要求1~4任一项所述的一种儿茶素漱口水的制备方法,其特征在于,所述表面活性剂为吐温-20。
6.权利要求1~5任一项所述制备方法获得的儿茶素漱口水。
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