CN105497517A - 一种治疗气血两虚型产后腹痛的中药组合物及其制备方法 - Google Patents
一种治疗气血两虚型产后腹痛的中药组合物及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗气血两虚型产后腹痛的中药组合物及其制备方法,其特征在于,由下列重量配比的药材制成:波罗蜜核中仁80-120份、翅果藤20-40份、冬葵4-16份、金橘根4-12份、大枣4-16份、雪山芪4-16份、龙眼肉9-21份、豹皮菇9-21份、玉竹4-16份、蕨麻10-30份、东当归10-30份、乌药4-16份、地笋1-9份、甘草2-10份。本发明的中药组合物,用于治疗气血两虚型产后腹痛,有效率高,疗效可靠。
Description
技术领域
本发明涉及一种治疗气血两虚型产后腹痛的中药组合物及其制备方法。
背景技术
产后腹痛是指以新产后出现小腹阵阵作痛难忍为主要表现的产后疾病。产后腹痛多因产后气血运行不畅,子宫收缩所致。多发于产后3~4天,下腹部阵发性疼痛,或隐隐作痛多日不缓解,无寒热现象,恶露可有异常变化,腹痛可因哺乳而加重。中医根据不同原因引起的产后腹痛,结合临床实际进行辨证治疗,将本病分为:气血两虚型、瘀滞子宫型。目前,西医治疗该病多采取服用止痛的方式,治标不治本,而且影响母乳的质量。而中医治疗不仅治愈速度快,愈后不再复发,能够达到标本兼治的效果,无任何副作用,对身体健康还有补血养血的调理作用。目前,治疗产后腹痛的中药有很多种,但是针对于气血两虚型产后腹痛的中药并不多见,而且大多数还存在治愈缓慢等缺陷。
发明内容
为解决上述现有的缺点,本发明的主要目的在于提供一种实用的治疗气血两虚型产后腹痛的中药组合物及其制备方法,通过选择合适的药材及其配比,达到安全有效治愈气血两虚型产后腹痛的目的。
为达成以上所述的目的,本发明的一种治疗气血两虚型产后腹痛的中药组合物及其制备方法采取如下技术方案:
一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁80-120份、翅果藤20-40份、冬葵4-16份、金橘根4-12份、大枣4-16份、雪山芪4-16份、龙眼肉9-21份、豹皮菇9-21份、玉竹4-16份、蕨麻10-30份、东当归10-30份、乌药4-16份、地笋1-9份、甘草2-10份。
本发明优选的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁90-110份、翅果藤25-35份、冬葵7-13份、金橘根6-10份、大枣7-13份、雪山芪7-13份、龙眼肉12-18份、豹皮菇12-18份、玉竹7-13份、蕨麻15-25份、东当归15-25份、乌药7-13份、地笋3-7份、甘草4-8份。
本发明最佳的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁100份、翅果藤30份、冬葵10份、金橘根8份、大枣10份、雪山芪10份、龙眼肉15份、豹皮菇15份、玉竹10份、蕨麻20份、东当归20份、乌药10份、地笋5份、甘草6份。
本发明的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,采用下述方法制备:
A:称取重量配比的波罗蜜核中仁、翅果藤、冬葵、金橘根、大枣、雪山芪、龙眼肉、豹皮菇、玉竹、蕨麻、东当归、乌药、地笋和甘草备用;
B:将上述十四味药材倒入器皿内,加8倍量水,煎煮1.5小时,过滤;
C:滤渣加6倍量水,煎煮1小时,过滤;
D:合并滤液,浓缩,干燥,装入胶囊壳即可。
配方中所涉及到的药材的来源及功能主治如下:
波罗蜜核中仁【来源】药材基源:为桑科植物木波罗的种仁。【性味】甘;微酸;性平【功能主治】益气;通乳。主产后脾虚气弱;乳少或乳汁不行。
翅果藤【来源】萝藦科翅果藤Myriopteronextensam(Wight)K.Schum.,以根入药。【性味】甘、苦,辛。【功能主治】补中益气,止咳,调经。主治感冒,咳嗽,月经过多,子宫脱垂,脱肛。
冬葵【来源】为锦葵科植物冬葵MalvaverticillataL.以根、茎、叶及子(冬葵果)入药。夏秋采挖带根全草,洗净切碎晒干。【性味】甘,温。【功能主治】补中益气;用于气虚乏力,腰膝酸软,体虚自汗,脱肛,子宫脱垂,慢性肾炎,糖尿病。
金橘根【来源】药材基源:为芸香科植物金橘Fortunellamargarita(Lour.)Swingle、金弹FortunellacrassifoliaSwingle、金柑Fortunellajaponica(Thunb.)Swingle的根。【性味】味酸;苦;性温【归经】脾;胃;肝经【功能主治】行气止痛;化痰散结。主胃脘胀痛;疝气;产后腹痛;子宫下垂;瘰疬初起。
大枣【来源】药材基源:为鼠李科植物枣的果实。【性味】甘;温【归经】脾;胃经【功能主治】补脾胃;益气血;安心神;调营卫;和药性。主脾胃虚弱;气血不足;食少便溏;倦怠乏力;心悸失眠;妇人脏躁;营卫不和。
雪山芪【来源】豆科雪山芪AstragalusbalfourianusSimpson,以根入药。【性味】甘,温。【功能主治】补中益气,壮阳益肾。治体虚,贫血,产后虚弱,子宫脱垂,脱肛,自汗。
龙眼肉【来源】药材基源:为无患子科植物龙眼的假种皮。【性味】甘;温【归经】心;肾;肝;脾经【功能主治】补心脾;益气血;安心神。主心脾两虚;气血不足所致的惊悸;怔忡;失眠;健忘;血虚萎黄;有经不调;崩漏。
豹皮菇【来源】药材基源:为白蘑科真菌洁丽香菇的子实体。【性味】甘;平【归经】心;脾经【功能主治】补气血;益心肝。主气血不足;心脾两虚;疲乏无力;失眠心悸。
玉竹【来源】药材基源:为百合科植物玉竹的根茎。【性味】甘;平【归经】肺;胃经【功能主治】滋阴润肺;养胃生津。主燥咳;劳嗽;热病阴液耗伤之咽干口渴;内热消渴;阴虚外感;头昏眩晕;筋脉挛痛。
蕨麻【来源】药材基源:为蔷薇科植物蕨麻的块根。【性味】甘;苦;寒【归经】脾;胃经【功能主治】补气血;健脾胃;生津止渴。主脾虚泄泻;病后贫血;营养不良;水肿;风湿痹痛。
东当归【来源】药材基源:为伞形科植物东当归的根。【性味】味辛;甘;性温【功能主治】活血;调经止痛;润燥滑肠。主血虚证;月经不调;痛经;经闭;产后腹痛;肠燥便秘。
乌药【来源】药材基源:为樟科植物乌药的根。【性味】辛;温【归经】脾;胃、肝、肾、膀胱【功能主治】行气止痛;温肾散寒。主胸胁满闷;脘腹胀痛;头痛;寒疝疼痛;痛经及产后腹痛;尿频;遗尿。
地笋【来源】药材基源:为唇形科植物地笋和毛叶地笋的根茎。【性味】味甘;辛;性平【功能主治】化瘀止血;益气利水。主衄血;吐血;产后腹痛;黄疸;带下;气虚乏力。
甘草【来源】本品为豆科植物甘草GlycyrrhizauralensisFisch.、胀果甘草GlycyrrhizainflataBat.或光果甘草GlycyrrhizaglabraL.的干燥根。【性味】甘,平。【归经】归心、肺、脾、胃经。【功能主治】补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药。用于脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性。
气血两虚型产后腹痛临床表现为产后小腹隐隐作痛数日不止,喜按喜揉,恶露量少,色淡红,质稀无块;面色苍白,头晕眼花,心悸怔仲,大便干结;舌质淡,苔薄白,脉细弱。本发明采用适宜的药材和配比,各药物之间相互配合,协同作用,能有效治疗气血两虚型产后腹痛,三年来,通过对52例患者的使用表明,总有效率达96%。
下面结合临床实验数据说明本发明的有益效果:
1、一般资料
发明人2011年4月-2014年5月间共收集了52例气血两虚型产后腹痛的门诊患者,年龄22-38岁,随机分为:治疗组52例,对照组46例。两组年龄等资料无显著性差异,具有可比性。
2、试验方法
2.1对照组口服益母草膏,按照说明书服用。疗程2周。
2.2治疗组口服本发明按照具体实施例1制得的胶囊,早、中、晚各一次。疗程2周。
3、疗效标准及治疗结果
3.1疗效标准:
痊愈:气血两虚型产后腹痛的临床症状、体征消失。无效:气血两虚型产后腹痛的临床症状、体征均无明显改善或加重。
3.2治疗统计结果见表1。
表1两组疗效比较
组别 | n | 痊愈 | 无效 | 总有效率(%) |
治疗组 | 52 | 50 | 2 | 96% |
对照组 | 46 | 39 | 7 | 84.7% |
下面举出三个典型病例进一步说明本发明的效果:
1、王某,女,24岁,产后数日面色苍白,小腹隐隐作痛,恶露质稀五块,我处诊断为气血两虚型产后腹痛。服用本药方3天后,症状有所缓解,3天后症状全消,痊愈。
2、徐某,女,32岁,产后小腹疼痛,按揉后痛减,时常头晕眼花,心悸怔仲,在我处诊断为气血两虚型产后腹痛。服用本药方2天后,症状缓解,后又连续服用7天,症状全消,痊愈。
3、鹿某,女,35岁,产后腹痛,恶露量少,色淡红但无块,大便干燥,舌质淡,苔薄白,脉细弱,在我处诊断为气血两虚型产后腹痛。服用本药方4天后,症状即基本消失,后又服用4天进行了巩固治疗,痊愈。
具体实施方式
为了更好地理解与实施本发明,下面结合具体实施的例子对本发明做进一步详细的描述。
实施例1
称取波罗蜜核中仁100克、翅果藤30克、冬葵10克、金橘根8克、大枣10克、雪山芪10克、龙眼肉15克、豹皮菇15克、玉竹10克、蕨麻20克、东当归20克、乌药10克、地笋5克、甘草6克,加8倍量水,煎煮1.5小时,过滤;滤渣加6倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,装入胶囊壳,即得符合正常成人1天用量的胶囊剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例2
称取波罗蜜核中仁100克、翅果藤30克、冬葵10克、金橘根8克、大枣10克、雪山芪10克、龙眼肉15克、豹皮菇15克、玉竹10克、蕨麻20克、东当归20克、乌药10克、地笋5克、甘草6克,加10倍量水,煎煮2小时,过滤;滤渣加8倍量水,煎煮1.5小时,过滤;合并滤液,浓缩,干燥,包装,即得符合正常成人1天用量的散剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例3
称取波罗蜜核中仁100克、翅果藤30克、冬葵10克、金橘根8克、大枣10克、雪山芪10克、龙眼肉15克、豹皮菇15克、玉竹10克、蕨麻20克、东当归20克、乌药10克、地笋5克、甘草6克,加8倍量水,煎煮1.5小时,过滤;滤渣加6倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥按照本领域常规工艺制粒,包装,即得符合正常成人1天用量的颗粒剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例4
称取波罗蜜核中仁90克、翅果藤25克、冬葵7克、金橘根6克、大枣7克、雪山芪7克、龙眼肉12克、豹皮菇12克、玉竹7克、蕨麻15克、东当归15克、乌药7克、地笋3克、甘草4克,加8倍量水,煎煮1.5小时,过滤;滤渣加6倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,装入胶囊壳,即得符合正常成人1天用量的胶囊剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例5
称取波罗蜜核中仁110克、翅果藤35克、冬葵13克、金橘根10克、大枣13克、雪山芪13克、龙眼肉18克、豹皮菇18克、玉竹13克、蕨麻25克、东当归25克、乌药13克、地笋7克、甘草8克,加8倍量水,煎煮1.5小时,过滤;滤渣加6倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥,装入胶囊壳,即得符合正常成人1天用量的胶囊剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例6
称取波罗蜜核中仁120克、翅果藤40克、冬葵16克、金橘根12克、大枣16克、雪山芪16克、龙眼肉21克、豹皮菇21克、玉竹16克、蕨麻30克、东当归30克、乌药16克、地笋9克、甘草10克,加10倍量水,煎煮2小时,过滤;滤渣加8倍量水,煎煮1.5小时,过滤;合并滤液,浓缩,干燥,包装,即得符合正常成人1天用量的散剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
实施例7
称取波罗蜜核中仁80克、翅果藤20克、冬葵4克、金橘根4克、大枣4克、雪山芪4克、龙眼肉9克、豹皮菇9克、玉竹4克、蕨麻10克、东当归10克、乌药4克、地笋1克、甘草2克,加8倍量水,煎煮1.5小时,过滤;滤渣加6倍量水,煎煮1小时,过滤;合并滤液,浓缩,干燥按照本领域常规工艺制粒,包装,即得符合正常成人1天用量的颗粒剂。
用于治疗气血两虚型产后腹痛。口服,每日分早、中、晚三次服用。
以上通过对所列实施方式的介绍,阐述了本发明的基本构思和基本原理。但本发明绝不限于上述所列实施方式,凡是基于本发明的技术方案所作的等同变化、改进及故意变劣等行为,均应属于本发明的保护范围。
Claims (4)
1.一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁80-120份、翅果藤20-40份、冬葵4-16份、金橘根4-12份、大枣4-16份、雪山芪4-16份、龙眼肉9-21份、豹皮菇9-21份、玉竹4-16份、蕨麻10-30份、东当归10-30份、乌药4-16份、地笋1-9份、甘草2-10份。
2.根据权利要求1所述的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁90-110份、翅果藤25-35份、冬葵7-13份、金橘根6-10份、大枣7-13份、雪山芪7-13份、龙眼肉12-18份、豹皮菇12-18份、玉竹7-13份、蕨麻15-25份、东当归15-25份、乌药7-13份、地笋3-7份、甘草4-8份。
3.根据权利要求1所述的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,由下列重量配比的药材制成:
波罗蜜核中仁100份、翅果藤30份、冬葵10份、金橘根8份、大枣10份、雪山芪10份、龙眼肉15份、豹皮菇15份、玉竹10份、蕨麻20份、东当归20份、乌药10份、地笋5份、甘草6份。
4.根据权利要求1~3任一所述的一种治疗气血两虚型产后腹痛的中药组合物,其特征在于,采用下述方法制备:
A:称取重量配比的波罗蜜核中仁、翅果藤、冬葵、金橘根、大枣、雪山芪、龙眼肉、豹皮菇、玉竹、蕨麻、东当归、乌药、地笋和甘草备用;
B:将上述十四味药材倒入器皿内,加8倍量水,煎煮1.5小时,过滤;
C:滤渣加6倍量水,煎煮1小时,过滤;
D:合并滤液,浓缩,干燥,装入胶囊壳即可。
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