CN104306575A - 一种治疗气滞型癥瘕病的中药 - Google Patents
一种治疗气滞型癥瘕病的中药 Download PDFInfo
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Abstract
本发明公开了一种治疗气滞型癥瘕病的中药，其特征是由下列重量配比的药材制成的：绿萼梅8份、玫瑰花8份、香橼10份、青皮12份、赤腹松鼠粉3份、青头菌12份、素馨花12份、佛手10份、番红花18份、金盏菊根30份、蓼实18份、甘草6份。配方中的各药物之间相互配合，协同作用，共凑疏肝解郁，行气散结的功效，能有效治疗气滞型癥瘕病，八年来，通过对40名患者的使用表明，有效率达95％。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗气滞型癥瘕病的中药。
背景技术
妇科症瘕涵盖了各种妇科良性肿瘤，病种较多，是妇科常见病、疑难病症。它是以女子胞中有结块、胀满、疼痛或伴有出血者为主证，按之形证可验，坚硬不移，痛有定处者为徵；聚散无常，推之游移不定，痛无定处者为瘕。多因正气虚弱、情志抑郁、气血失调所致。病机多因脏腑失调，气血阻滞，瘀血内结，气聚为瘕，血瘀为症。证候以气滞、血瘀、痰湿、湿热等四型多见。腹中结成的块，坚硬不移动，痛有定处者为″症″，聚散无常，痛无定处则为″瘕″。辨证要点是按包块的性质、大小、部位、病程的长短、兼症和月经情况辨其在气在血，属痰湿还是热毒。目前，治疗癥瘕病的方法有西医治疗、手术治疗、中医治疗等方法，中医治疗是行之有效且安全的治疗方法。目前所公开的治疗癥瘕病的中成药有几种，但针对于治疗气滞型癥瘕病的中药并不多见。
发明内容
本发明的目的旨在提供一种治疗气滞型癥瘕病的中药，通过选择合适的药材及其配比，达到安全有效治愈气滞型癥瘕病的目的。
为达到上述目的，本发明采用以下技术方案：一种治疗气滞型癥瘕病的中药，其特征是由下列重量配比的药材制成的：
绿萼梅8份、玫瑰花8份、香橼10份、青皮12份、赤腹松鼠粉3份、青头菌12份、素馨花12份、佛手10份、番红花18份、金盏菊根30份、蓼实18份、甘草6份。
配方中所述的各种药材的来源及功能主治如下：
绿萼梅【来源】蔷薇科梅属植物绿萼梅Prunus mume Sieb.et Zucc.var.viridicalyx Makino，以花入药。【性味】苦、微甘，平。【功能主治】疏肝解郁，开胃升津。用于胸闷不舒、胃纳不佳及梅核气。
玫瑰花【来源】本品为蔷薇科植物玫瑰Rosa rugosa Thunb.的干燥花蕾。【性味】甘、微苦，温。【归经】归肝、脾经。【功能主治】行气解郁，和血，止痛。用于肝胃气痛，食少呕恶，月经不调，跌扑伤痛。
香橼【来源】本品为芸香科植物枸橼Citrus medica L.或香圆(西南香圆)Citrus wilsonii Tanaka的干燥成熟果实。【性味】辛、苦、酸，温。【归经】归肝、脾、肺经。【功能主治】舒肝理气，宽中，化痰。用于肝胃气滞，胸胁胀痛，脘腹痞满，呕吐噫气，痰多咳嗽。
青皮【来源】本品为芸香科植物橘Citrus reticulata Blanco及其栽培变种的干燥幼果或未成熟果实的果皮。【性味】苦、辛，温。【归经】归肝、胆、胃经。【功能主治】疏肝破气，消积化滞。用于胸胁胀痛，疝气，乳核，乳痈，食积腹痛。
赤腹松鼠【来源】药材基源：为松鼠科动物赤腹松鼠去内脏的全体。【性味】味甘；咸；性平。【归经】肺；肝经。【功能主治】活血调经；行气止痛。主跌打伤痛；骨折；月经不调；闭经；痛经。
青头菌【来源】药材基源：为红菇科真菌绿红菇的子实体。【性味】甘；微酸；性寒。【功能主治】清肝明目，理气解郁。主治肝热目赤；目暗不明；妇女肝郁内热；胸闷不舒。
素馨花【来源】为木犀科植物素馨花的干燥花蕾。【性味】微苦；性平。【归经】肝经。【功能主治】舒肝解郁；行气止痛。主治肝郁气滞所致的胁肋脘腹作痛；下痢腹痛。
佛手【来源】本品为芸香科柑橘属植物佛手Citrus medica L. var.sarcodactylis Swingle的干燥果实。【性味】辛、苦、酸，温。【归经】归肝、脾、肺经。【功能主治】舒肝理气，和胃止痛。用于肝胃气滞，胸胁胀痛，胃脘痞满，食少呕吐。
番红花【来源】本品为鸢尾科植物番红花crocus sativus l.的柱头。【性味】性平，味甘。【功能主治】活血化瘀，凉血解毒，解郁安神。用于经闭症瘕、产后瘀阻、温毒发斑、忧郁痞闷、惊悸发狂。
金盏菊根【来源】药材基源：为菊科植物金盏菊的根。【性味】味微苦；性平。【功能主治】活血散瘀；行气止痛。主治症瘕；疝气；胃寒疼痛。
蓼实【来源】药材基源：为蓼科植物水蓼的果实。【性味】辛；性温。【归经】肺；脾；肝经。【功能主治】化湿利水；破瘀散结；解毒。主治吐泻腹痛；水肿；小便不利；症积痞胀；痈肿疮疡；瘰疬。
甘草【来源】本品为豆科植物甘草Glycyrrhiza uralensisFisch.、胀果甘草Glycyrrhiza inflata Bat.或光果甘草Glycyrrhiza glabra L.的干燥根。【性味】甘，平。【归经】归心、肺、脾、胃经。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
气滞型癥瘕病是因七情所伤，肝气郁结，气血运行受阻，滞于冲任胞宫，结块积于小腹，成为气滞症瘕。其主要证候为小腹有包块，积块不坚，推之可移，时聚时散，或上或下，时感疼痛，痛无定处，小腹胀满，胸闷不舒，精神抑郁，月经不调，舌红，苔薄，脉沉弦。证候分析：瘕乃气聚而成，故小腹有包块，积块不坚，推之可移，时聚时散，或上或下，气滞则痛，气散则止，故时痛时止，痛无定处；肝失条达，气机不畅，故小腹胀满，胸闷不舒，精神抑郁；气滞冲任失司，则月经不调。舌红，苔薄，脉沉弦，为气滞之征。治疗法则：疏肝解郁，行气散结。本发明采用科学的配方及适合的配比，配方中所采用的绿萼梅具有疏肝解郁、开胃升津的功效；玫瑰花具有行气解郁、和血、止痛的功效；香橼具有舒肝理气、宽中的功效；青皮具有疏肝破气、消积化滞的功效；赤腹松鼠具有活血调经、行气止痛的功效；青头菌具有清肝明目、理气解郁的功效；素馨花具有舒肝解郁、行气止痛的功效；佛手具有舒肝理气、和胃止痛的功效；番红花具有活血化瘀、凉血解毒、解郁安神的功效；金盏菊根具有活血散瘀、行气止痛的功效；蓼实具有化湿利水、破瘀散结、解毒的功效；甘草具有补脾益气，清热解毒，调和诸药的功效。配方中的各药物之间相互配合，协同作用，共凑疏肝解郁，行气散结的功效，能有效治疗气滞型癥瘕病，八年来，通过对40名患者的使用表明，有效率达95％。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2005年4月-2013年9月间共收集了80例气滞型癥瘕病的门诊患者，年龄29-55岁。症状表现为小腹有包块，积块不坚，推之可移，时聚时散，或上或下，时感疼痛，痛无定处，小腹胀满，胸闷不舒，精神抑郁，月经不调，舌红，苔薄，脉沉弦。检查：妇科检查，采用B超、宫腔镜、腹腔镜、子宫输卵管造影等检查协助确诊。结合相关的肿瘤标志物检查等，排除恶性肿瘤。随机分为：治疗组40例，对照组40例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组服用香棱丸(《济生方》【处方举例】木香6g，丁香3g，小茴香5g，枳壳10g，川楝子10g，青皮8g，三棱8g，莪术8g。)，按照说明书服用。疗程为三个月经周期。
2.2治疗组口服本发明按照具体实施例1制得的胶囊，早、晚各一次。疗程为三个月经周期。
3、疗效标准及治疗结果
3.1疗效标准：
痊愈：症状全部消失，卵巢巧克力样囊肿经妇科检查，B超检查盆腔包块等局部体征基本消失。
显效：症状基本消失，卵巢巧克力样囊肿经妇科检查，B超检内膜异位囊肿三径之和缩小1/2以上，临床症状部分或全部消失。
有效：症状减轻，卵巢巧克力样囊肿经妇科检查，B超检查囊肿三径之和缩小1/3以上，临床症状部分消失或减轻。
无效：连续服药一个疗程以上，B超检查囊肿三径之和无改变或缩小不足1cm，自觉症状减轻或无改变。
3.2治疗统计结果见表1。
表1 两组疗效比较
由此可见，本发明制得的药物能够安全有效治疗气滞型癥瘕病。
具体实施方式
为了更好地理解与实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取绿萼梅8克、玫瑰花8克、香橼10克、青皮12克、青头菌12克、素馨花12克、佛手10克、番红花18克、金盏菊根30克、蓼实18克、甘草6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，与3克赤腹松鼠粉混合均匀，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗气滞证型癥瘕病，口服，每日分早、中、晚三次服用。
具体实施例2
称取绿萼梅8克、玫瑰花8克、香橼10克、青皮12克、青头菌12克、素馨花12克、佛手10克、番红花18克、金盏菊根30克、蓼实18克、甘草6克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，与3克赤腹松鼠粉混合均匀，包装，即得符合正常成人1天用量的散剂。
用于治疗气滞证型癥瘕病，口服，每日分早、中、晚三次服用。
具体实施例3
称取绿萼梅8克、玫瑰花8克、香橼10克、青皮12克、青头菌12克、素馨花12克、佛手10克、番红花18克、金盏菊根30克、蓼实18克、甘草6克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，与3克赤腹松鼠粉混合均匀，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗气滞证型癥瘕病，口服，每日分早、中、晚三次服用。
Claims (1)
1.一种治疗气滞型癥瘕病的中药，其特征是由下列重量配比的药材制成的：
绿萼梅8份、玫瑰花8份、香橼10份、青皮12份、赤腹松鼠粉3份、青头菌12份、素馨花12份、佛手10份、番红花18份、金盏菊根30份、蓼实18份、甘草6份。
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