CN105456599A - Xianglian stagnation removing pills and preparing method thereof - Google Patents

Xianglian stagnation removing pills and preparing method thereof Download PDF

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CN105456599A
CN105456599A CN201510890596.1A CN201510890596A CN105456599A CN 105456599 A CN105456599 A CN 105456599A CN 201510890596 A CN201510890596 A CN 201510890596A CN 105456599 A CN105456599 A CN 105456599A
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stir
pericarpium citri
citri reticulatae
powder
fry
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不公告发明人
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Heilongjiang Jiangheng Pharmaceutical Co Ltd
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Heilongjiang Jiangheng Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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    • A61K2236/50—Methods involving additional extraction steps
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

The invention discloses xianglian stagnation removing pills and a preparing method thereof. The preparing method is characterized in that 68 g of herba artemisiae capillariae, 136 g of schisandra chinensis, 6.8 g of herba elsholtziae, 68 g of scutellaria baicalensis, 68 g of fructus aurantii immaturus (stir-fried with bran), 68 g of pericarpium citri reticulatae, 68 g of pericarpium citri reticulatae viride (stir-fried with vinegar), 68g of mangnolia officinalis (stir-fried with ginger), 55 g of areca nuts (stir-fried), 55 g of talc, 204 g of radix paeoniae alba (stir-fried) and 136 g of radix angelica sinensis are taken and smashed into coarse powder, the coarse powder is placed into a circular ultrasonic extractor, water, germanium powder and Tween 60 are added, nano extract powder is obtained through ultrasonic extraction and jet flow spray drying, honey is refined to form pills, and the xianglian stagnation removing pills are prepared. The xianglian stagnation removing pills are used for treating tenesmus and stomachache diarrhea caused by pathogenic warm, and have a good effect, and the treatment effect is better than that of xianglian stagnation removing pills sold in the market.

Description

Stagnant ball of a kind of fragrant fluidization and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to stagnant ball of a kind of fragrant fluidization and preparation method thereof.
Background technology
The stagnant ball clearing away heat-damp and promoting diuresis of fragrant fluidization, promoting the circulation of bloodization is stagnant.For the warm tenesmus caused that stagnates, stomachache dysentery.The stagnant ball of commercially available fragrant fluidization is due to prescription and technological reason, and curative effect is not satisfactory, and preparation adopts traditional handicraft preparation, there is the shortcoming that curative effect is low.
Summary of the invention
The present invention for overcoming above-mentioned deficiency, stagnant ball of fragrant fluidization providing a kind of curative effect high and preparation method thereof.
Invention embodiment is as follows:
Get Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 6 ~ 8g germanium powder, 6 ~ 8g polysorbate60, select supersonic frequency 50 ~ 60KHz, pressure 0.4 ~ 0.6Mpa extracts 30 minutes, use 80 mesh screen, obtain extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 38 ~ 48 DEG C, pressure 0.02 ~ 0.04Mpa, 400 ~ 600 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 20-30g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
The raw material standards that above-mentioned embodiment is mentioned is as follows:
Herba Artemisiae Scopariae: China's coastal port one ministerial standard.This product is the dry aerial parts of feverfew Artemisia scoparia Waldst. et Kit. ArtemisiascopariaWaldst.etKit. or Herba Artemisiae Scopariae ArtemisiacapillarisThunb..Gather during seedling height 6-10cm in spring or autumn, alabastrum grew up to time tap, removing impurity and old stem, dries.The habit of gathering spring claims " capillary wormwood ", the title " Herba Artemisiae Scopariae " tapped autumn.This product is On Polyporaceae Poria Poriacocos(Schw.) dry sclerotia of Wolf.Excavate more than the 7-9 month, dig out rear removing silt, bank up after " diaphoresis ", spread out and dry in the air to dry tack free, then " diaphoresis ", after extremely now scatter and disappear in wrinkle, the large portion of internal moisture for several times repeatedly, dry in the shade, be called " Poria "; Or fresh Poria is pressed different parts cutting, cloudy in, be called " Cortex Sclerotii Poriae " and " Poria block ".
Fructus Schisandrae Chinensis: China's coastal port one ministerial standard.This product is magnoliaceae schisandra Schisandrachfnensis(Turcz.) dry mature fruit of Baill., practise and claim " Radix Schisandrae Bicoloris ".Pluck during fruit maturation in autumn, dry or dry after steaming, removing carpopodium and impurity.
Herba Moslae: China's coastal port one ministerial standard.This product is the ten dry aerial partss of labiate Mosla chinensis Maxim. MislachinensisMaxim. or Mosla chinensis Maxim.cv.Jiangxiangru Moslachinensis ' Jiangxiangru '.The former practises title " Chinese mosla ", and the latter practises title " Mosla chinensis Maxim.cv.Jiangxiangru ".Luxuriant, the colored flower of stem and leaf in summer is selected fine day and is tapped, and removing impurity, dries in the shade.
Radix Scutellariae: China's coastal port one ministerial standard.This product is the dry root of labiate Radix Scutellariae ScutellariabaicalensisGeorgi.Spring, Qiu Erji excavate, and removing fibrous root and silt, hit rough bark after solarization, dry.
Fructus Aurantii Immaturus: China's coastal port one ministerial standard.This product is the dry young fruit of rutaceae Citrus aurantium Linn. CitrusaurantiumL. and variety or Fructus Citri sinensis CitrussinensisOsbeck.Collect the fruit from falling the 5-6 month, removing impurity, be two halves from middle part crosscut, dry or cold drying, smaller directly dries or cold drying.
Pericarpium Citri Reticulatae: China's coastal port one ministerial standard.This product is the dry mature skin of rutaceae orange CitrusreticulataBlanco and variety thereof.Medical material is divided into " Pericarpium Citri Reticulatae " and " Pericarpium citri reticuatae chachiensis ".Harvesting ripe fruit, strips peel, dries or cold drying.
Pericarpium Citri Reticulatae Viride: China's coastal port one ministerial standard.This product is the dry young fruit of rutaceae orange CitrusreticulataBlanco and variety thereof or the peel of immature fruit.Collecting the young fruit from falling the 5-6 month, drying, practise and claim " FTUCTUS CITRI IMMATURI "; Gather the 7-8 month green fruit, on peel, vertical profile becomes pintongs to base portion, eliminates flesh lobe, dries, and practises and claims " Sihuaqingpi ".
Cortex Magnoliae Officinalis: China's coastal port one ministerial standard.This product is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis MignoliaofficinalisRehd.etWils. or magnolia officinalis rehd.et wils.var.biloba rehd.et wils. MignoliaofficinalisRehd.etWils.var.bilobaRehdetWils., root bark and branch skin.The 4-6 month strips, root bark and branch skin Directly Dried in Shadow; In skin put in boiling water micro-boil after, dark and damp place of banking up, when " diaphoresis " is to inner surface purpling brown or sepia, steams soft, takes out, is rolled into tubular, dry.
Semen Arecae: China's coastal port one ministerial standard.This product is the dry mature seed of babassu Semen Arecae ArecacatechuL..Gather at the beginning of spring Mo to autumn mature fruit, after decocting in water, dry, removing peel, takes out seed, dry.
Talcum: China's coastal port one ministerial standard.This product is silicates mineral talc race Talcum. main containing hydrous magnesium silicate (Mg3(Si4O10) (OH) 2) excavate after, removing silt and assorted stone.
The Radix Paeoniae Alba: China's coastal port one ministerial standard.This product is the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Summer, Qiu Erji dig, clean, removing end to end and radicula, put in boiling water boil rear removing crust or go should after boil again, dry.
Radix Angelicae Sinensis: China's coastal port one ministerial standard.This product is umbelliferae angelica Angelicasinensis(Oliv.) dry root of Diels.Autumn end excavates, and removing fibrous root and silt, after moisture slightly evaporates, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd.
Germanium powder: germanium dioxide: No. CAS: 1310-53-8: industry standard: lark prestige Science and Technology Ltd.;
Polysorbate60: Chinese Pharmacopoeia version two ministerial standard in 2010;
All can buy from pharmaceuticals with the raw material used by the stagnant ball of fluidization of going to temple to pray and obtain, be not limited to typical production producer, all can be used to implement the present invention program as long as meet quality standard.
The key equipment that foregoing invention embodiment is mentioned is as follows:
Circulating ultrasonic machine: supersonic frequency 20 ~ 100KHz,
(typical production producer: Beijing Hongxianglong Biotechnology Development Co., Ltd)
Jet spray dryer: inlet temperature scope 30 ~ 70 DEG C, 300 ~ 900 meters per second of effluxvelocity scope;
(typical production producer: Nai Nuo bio tech ltd, Beijing)
All can buy from pharmaceuticals with the raw material used by the stagnant ball of fluidization of going to temple to pray and obtain, all can be used to implement the present invention program as long as meet national standard.
In foregoing invention scheme, term used is pharmacy proprietary term, as " decompression ", " Rhizoma Zingiberis Recens is processed " etc. all defer to Chinese Pharmacopoeia regulation and pharmaceutical practice of being correlated with.
Unit g in the present invention also can be other weight portion, does not affect the enforcement of the present invention program.
Equipment Market described in the present invention program all has sale, is not limited to typical production producer, as long as technical specification can reach requirement, all can be used to realize the present invention.
Detailed description of the invention
Specific embodiments of the invention 1
Get Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 6g germanium powder, 6g polysorbate60, selects supersonic frequency 50KHz, pressure 0.4Mpa extracts 30 minutes, uses 80 mesh screen, obtains extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 38 DEG C, pressure 0.02Mpa, 400 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 20g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
Specific embodiments of the invention 2
Get Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 8g germanium powder, 8g polysorbate60, selects supersonic frequency 60KHz, pressure 0.6Mpa extracts 30 minutes, uses 80 mesh screen, obtains extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 48 DEG C, pressure 0.04Mpa, 600 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 30g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
Specific embodiments of the invention 3
Get Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 7g germanium powder, 7g polysorbate60, selects supersonic frequency 55KHz, pressure 0.5Mpa extracts 30 minutes, uses 80 mesh screen, obtains extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 43 DEG C, pressure 0.03Mpa, 500 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 25g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
Above embodiment illustrates, adopts the extreme condition of embodiment of the present invention and optimal conditions all can make the stagnant ball of fragrant fluidization.Actual effect of the present invention is investigated below with the stagnant ball of fragrant fluidization that embodiment 3 is obtained:
(1) the stagnant ball of the fragrant fluidization of embodiment 3 and the warm tenesmus caused that stagnates of the stagnant pill for curing of commercially available fragrant fluidization, stomachache dysentery clinical observation on the therapeutic effect
1 case scenario
Statistics outpatient service and inpatient, observe the warm tenesmus caused that stagnates altogether, stomachache dysentery case 102 example, 38 years old mean age.Patient is divided into two groups, test group takes the stagnant ball of the fragrant fluidization of embodiment 3, and matched group takes the stagnant ball of traditional fragrant fluidization.
2 efficacy assessment standards
According to new Chinese medicine guideline of clinical investigations tcm syndrome curative effect determinate standard:
Cure: tcm clinical practice symptom, sign disappear or substantially disappear, syndrome integral reduces >=95%.
Effective: tcm clinical practice symptom, sign are obviously improved, syndrome integral reduces >=70%.
Effective: tcm clinical practice symptom, sign all take a favorable turn, syndrome integral reduces >=30%.
Invalid: tcm clinical practice symptom, sign are all not improved or increase the weight of, syndrome integral reduces < 30%.
Computing formula: [before (before treatment the rear integration of integration-treatment) ÷ treatment integration] × 100%.
3 clinical observation result
The stagnant ball of the fragrant fluidization of table 1 embodiment 3 and the stagnant ball clinical efficacy contrast of commercially available fragrant fluidization
Above-mentioned clinical observation on the therapeutic effect result shows, the stagnant ball of fragrant fluidization prepared by the present invention is at the warm tenesmus caused that stagnates for the treatment of, during stomachache dysentery, evident in efficacy higher than the stagnant ball of commercially available fragrant fluidization, p < 0.05.

Claims (3)

1. treat the warm tenesmus caused that stagnates for one kind, the Chinese medicine of stomachache dysentery, it is characterized in that getting Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 6 ~ 8g germanium powder, 6 ~ 8g polysorbate60, select supersonic frequency 50 ~ 60KHz, pressure 0.4 ~ 0.6Mpa extracts 30 minutes, use 80 mesh screen, obtain extracting solution, getting extracting solution puts in jet spray dryer, and control inlet temperature 38 ~ 48 DEG C, pressure 0.02 ~ 0.04Mpa, 400 ~ 600 meters per second of flow velocity, obtains nanometer extract powder, every 100g nanometer extract powder refined honey 20-30g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
2. the preparation method of Chinese medicine according to claim 1, is characterized in that getting Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 6 ~ 8g germanium powder, 6 ~ 8g polysorbate60, select supersonic frequency 50 ~ 60KHz, pressure 0.4 ~ 0.6Mpa extracts 30 minutes, uses 80 mesh screen, obtains extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 38 ~ 48 DEG C, pressure 0.02 ~ 0.04Mpa, 400 ~ 600 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 20-30g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
3. the preparation method of Chinese medicine according to claim 1, is characterized in that getting Herba Artemisiae Scopariae 68g, Fructus Schisandrae Chinensis 136g, Herba Moslae 6.8g, Radix Scutellariae 68g, Fructus Aurantii Immaturus (parched with bran) 68g, Pericarpium Citri Reticulatae 68g, Pericarpium Citri Reticulatae Viride (process with vinegar) 68g, Cortex Magnoliae Officinalis (Rhizoma Zingiberis Recens is processed) 68g, Semen Arecae (stir-fry) 55g, Talcum 55g, the Radix Paeoniae Alba (stir-fry) 204g, Radix Angelicae Sinensis 136g, be ground into 40 order coarse powder, put in circulating ultrasonic extractor, add 9908g water, 7g germanium powder, 7g polysorbate60, select supersonic frequency 55KHz, pressure 0.5Mpa extracts 30 minutes, uses 80 mesh screen, obtains extracting solution; Getting extracting solution puts in jet spray dryer, and control inlet temperature 43 DEG C, pressure 0.03Mpa, 500 meters per second of flow velocity, obtains nanometer extract powder; Every 100g nanometer extract powder refined honey 25g adds appropriate water pill, dry, makes water-honeyed pill, the obtained stagnant ball of fragrant fluidization.
CN201510890596.1A 2015-12-08 2015-12-08 Xianglian stagnation removing pills and preparing method thereof Pending CN105456599A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236721A (en) * 2016-08-31 2016-12-21 太极集团浙江东方制药有限公司 A kind of preparation method of Guishaoliujun Pill

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106236721A (en) * 2016-08-31 2016-12-21 太极集团浙江东方制药有限公司 A kind of preparation method of Guishaoliujun Pill

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