CN105451771B - 可咀嚼配制物 - Google Patents

可咀嚼配制物 Download PDF

Info

Publication number
CN105451771B
CN105451771B CN201480027827.XA CN201480027827A CN105451771B CN 105451771 B CN105451771 B CN 105451771B CN 201480027827 A CN201480027827 A CN 201480027827A CN 105451771 B CN105451771 B CN 105451771B
Authority
CN
China
Prior art keywords
chewable
chewable formulation
formulation
agent
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480027827.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN105451771A (zh
Inventor
道格拉斯·罗伯特·克莱维利
大卫·安东尼·吉尔
凯琳·戴维斯
普里岩卡·阿加瓦
苏·温
戈皮纳特·戴瓦拉吉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Argentina Innovation Co Ltd
Original Assignee
Argentina Innovation Co ltd
Argenta Manufacturing Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51535990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN105451771(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Argentina Innovation Co ltd, Argenta Manufacturing Ltd filed Critical Argentina Innovation Co ltd
Priority to CN202010331694.2A priority Critical patent/CN111803465B/zh
Publication of CN105451771A publication Critical patent/CN105451771A/zh
Application granted granted Critical
Publication of CN105451771B publication Critical patent/CN105451771B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/168—Steroids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/184—Hormones
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/20—Shaping or working-up of animal feeding-stuffs by moulding, e.g. making cakes or briquettes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/25—Shaping or working-up of animal feeding-stuffs by extrusion
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A23K50/42—Dry feed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/148—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201480027827.XA 2013-03-15 2014-03-17 可咀嚼配制物 Active CN105451771B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010331694.2A CN111803465B (zh) 2013-03-15 2014-03-17 可咀嚼配制物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361793676P 2013-03-15 2013-03-15
US61/793,676 2013-03-15
PCT/IB2014/059911 WO2014141223A1 (en) 2013-03-15 2014-03-17 Chewable formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202010331694.2A Division CN111803465B (zh) 2013-03-15 2014-03-17 可咀嚼配制物

Publications (2)

Publication Number Publication Date
CN105451771A CN105451771A (zh) 2016-03-30
CN105451771B true CN105451771B (zh) 2020-05-19

Family

ID=51535990

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480027827.XA Active CN105451771B (zh) 2013-03-15 2014-03-17 可咀嚼配制物
CN202010331694.2A Active CN111803465B (zh) 2013-03-15 2014-03-17 可咀嚼配制物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202010331694.2A Active CN111803465B (zh) 2013-03-15 2014-03-17 可咀嚼配制物

Country Status (8)

Country Link
US (2) US9314478B2 (enExample)
EP (1) EP2968569A4 (enExample)
JP (2) JP6378702B2 (enExample)
CN (2) CN105451771B (enExample)
AU (5) AU2014229179C1 (enExample)
BR (1) BR112015023435B1 (enExample)
CA (1) CA2906295C (enExample)
WO (1) WO2014141223A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2968569A4 (en) * 2013-03-15 2016-11-02 Argenta Mfg Ltd COUGAR FORMULATION
DE202014006415U1 (de) * 2014-08-12 2015-11-13 Boehringer Ingelheim International Gmbh Wasserlösliches Granulat zur Herstellung einer Trinklösung
MX2017005721A (es) * 2014-11-03 2017-07-28 Zoetis Services Llc Composicion veterinaria masticable agradable al paladar.
US9808010B2 (en) 2015-07-06 2017-11-07 Virbac Corporation Chewable composition
EP3308773A1 (en) * 2016-10-11 2018-04-18 Recordati Industria Chimica E Farmaceutica SPA Formulations of cysteamine and cysteamine derivatives
US12115135B2 (en) * 2018-04-11 2024-10-15 Richard Postrel Anti-aging therapy for canines and other domesticated animals
CA3049952A1 (en) 2017-07-26 2019-01-31 Tgx Soft Chew, Llc Starch-free soft chew for veterinary applications
IL275144B2 (en) * 2017-12-08 2024-12-01 Hoffmann La Roche Pharmaceutical formulation
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
US20200146318A1 (en) * 2019-09-27 2020-05-14 Société des Produits Nestlé S.A. Edible chew for a human child and methods of making and using the edible chew
EP3878436A1 (en) 2020-03-09 2021-09-15 Bayer Animal Health GmbH Soft chewable formed body for the administration to animals
JP7403001B2 (ja) * 2020-05-06 2023-12-21 マース インコーポレーテッド 医薬品の投与のための嗜好性支持体組成物
WO2022069922A1 (es) * 2020-09-30 2022-04-07 Procaps S.A. Formulación de ivermectina en cápsulas blandas de gelatina
JP2024514002A (ja) * 2021-04-15 2024-03-27 ジボダン エス エー 味改変剤
NL2028708B1 (en) * 2021-07-13 2023-01-18 Stabican B V Process for preparing cannabinoid-containing particles
FR3138315A1 (fr) 2022-07-27 2024-02-02 Virbac Produit à usage vétérinaire et procédé pour sa fabrication
WO2025029582A2 (en) * 2023-08-01 2025-02-06 Rubicon Scientific, Llc Maintaining diethylcarbamazine in an extruded daily ration animal feed product
WO2025111456A1 (en) * 2023-11-21 2025-05-30 Bimini, Llc Compositions for inducing saliva and release of calcium chelators and antimicrobials in oral cavity

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1188646A (zh) * 1997-01-24 1998-07-29 赫彻斯特股份公司 制备味道被掩盖的抗菌活性的喹喏酮衍生物制剂
CN1273527A (zh) * 1997-10-03 2000-11-15 Fmc公司 遮味药物组合物
US6387381B2 (en) * 1998-09-24 2002-05-14 Ez-Med Company Semi-moist oral delivery system
US20050226908A1 (en) * 2004-04-07 2005-10-13 Akzo Nobel N.V. Efficacious composition of a benzimidazole, an avermectin and praziquantel and related methods of use
CN1829448A (zh) * 2003-07-30 2006-09-06 诺瓦提斯公司 适口的可塑可咀嚼兽用组合物
WO2008134819A1 (en) * 2007-05-07 2008-11-13 Jurox Pty Ltd Improved dosage form and process
US20100104688A1 (en) * 2007-07-06 2010-04-29 Carsten Andersen Chewing Gum Granules For Compressed Chewing Gum
US20100215799A1 (en) * 2007-02-26 2010-08-26 Revolymer Limited Chewing gum composition
CN101909605A (zh) * 2007-11-14 2010-12-08 皮埃蒙特医药品有限公司 制造用于药物递送的咀嚼剂型的方法及其产品
CN102238940A (zh) * 2008-12-05 2011-11-09 拜尔动物保健有限责任公司 含针状活性物质的挤出物

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2857897B2 (ja) * 1989-12-11 1999-02-17 株式会社山海 膨化成形食品
US5380535A (en) 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
US5296209A (en) 1992-01-17 1994-03-22 Colgate Palmolive Company Pet chew product having oral care properties
JPH10501211A (ja) 1994-05-20 1998-02-03 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 飼育動物用のチュワブル・フルベンダゾール錠剤
US6672252B2 (en) 2002-01-31 2004-01-06 Sergeant's Pet Products, Inc. Pet chew
US20050271708A1 (en) 2002-03-05 2005-12-08 Thombre Avinash G Palatable controlled-release formulation for companion animals
US20040151759A1 (en) 2002-08-16 2004-08-05 Douglas Cleverly Non-animal product containing veterinary formulations
US20040037869A1 (en) 2002-08-16 2004-02-26 Douglas Cleverly Non-animal product containing veterinary formulations
ES2457078T3 (es) * 2003-01-27 2014-04-24 Nestec S.A. Utilización de constituyentes expandidos y fabricación de productos a partir de los mismos
AU2008201605B2 (en) 2003-07-30 2010-04-29 Novartis Ag Palatable ductile chewable veterinary composition
EP1523892A1 (en) 2003-10-17 2005-04-20 Paragon Products B.V. i.o. Pet's chew
EP1602285A1 (en) 2004-06-04 2005-12-07 Gaines Treats Limited A process for preparing a chewable pet food
US20110097330A1 (en) 2005-03-11 2011-04-28 Genentech, Inc. Novel Gene Disruptions, Compostitions and Methods Relating Thereto
US7348027B2 (en) 2005-04-08 2008-03-25 Bayer Healthcare Llc Taste masked veterinary formulation
US20070148282A1 (en) 2005-12-02 2007-06-28 Mars, Inc. Performance Oral Snack
US20070128251A1 (en) 2005-12-07 2007-06-07 Piedmont Pharmaceuticals, Inc. Process for manufacturing chewable dosage forms for drug delivery and products thereof
EP1800545A1 (en) 2005-12-23 2007-06-27 Nestec S.A. Pet food and processes of producing the same
ES2303446B1 (es) 2006-07-03 2009-07-28 Viscofan, S.A. Producto masticable y/o comestible para mascotas y animales.
AU2007293068C1 (en) 2006-09-07 2013-09-19 Boehringer Ingelheim Animal Health USA Inc. Soft chewable, tablet, and long-acting injectable veterinary antibiotic formulations
US8455025B2 (en) 2010-04-21 2013-06-04 Petmatrix LLC Edible pet chew made from a single initially malleable sheet
NZ579205A (en) * 2007-02-26 2012-03-30 Revolymer Ltd Chewing gum containing an amphiphilic polymer which controls the release of a drug or other biologically active material
US20080293645A1 (en) 2007-05-25 2008-11-27 Schneider Lawrence F Antiparasitic combination and method for treating domestic animals
AU2008259951B2 (en) * 2007-06-01 2011-10-06 Intercontinental Great Brands Llc Center-fill gum compositions incorporating triacetin
BRPI0809770B8 (pt) 2007-06-13 2022-12-06 Du Pont Composto e composição para controlar uma praga de invertebrados
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
JP5608653B2 (ja) 2008-09-04 2014-10-15 ファーナム・カンパニーズ・インコーポレーテッド チュアブルな徐放性製剤
EP2348891B1 (en) * 2008-09-12 2015-10-21 Solae, Llc Functional food paste
MX2012013758A (es) 2010-05-27 2013-01-24 Du Pont Forma cristalina de 4-[5-[3-cloro-5-trifluorometil)fenil]-4,5-dihi dro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoro etil)amino]etil]-1-naftalenocarboxamida.
PH12018501647A1 (en) 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
WO2013068371A1 (en) 2011-11-08 2013-05-16 Intervet International B.V. Soft chewable dosage form compositions of cannabinoid receptor type 1 (cb-1) antagonists
SG11201404595TA (en) * 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
EP2968569A4 (en) * 2013-03-15 2016-11-02 Argenta Mfg Ltd COUGAR FORMULATION

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1188646A (zh) * 1997-01-24 1998-07-29 赫彻斯特股份公司 制备味道被掩盖的抗菌活性的喹喏酮衍生物制剂
CN1273527A (zh) * 1997-10-03 2000-11-15 Fmc公司 遮味药物组合物
US6387381B2 (en) * 1998-09-24 2002-05-14 Ez-Med Company Semi-moist oral delivery system
CN1829448A (zh) * 2003-07-30 2006-09-06 诺瓦提斯公司 适口的可塑可咀嚼兽用组合物
US20050226908A1 (en) * 2004-04-07 2005-10-13 Akzo Nobel N.V. Efficacious composition of a benzimidazole, an avermectin and praziquantel and related methods of use
US20100215799A1 (en) * 2007-02-26 2010-08-26 Revolymer Limited Chewing gum composition
WO2008134819A1 (en) * 2007-05-07 2008-11-13 Jurox Pty Ltd Improved dosage form and process
US20100104688A1 (en) * 2007-07-06 2010-04-29 Carsten Andersen Chewing Gum Granules For Compressed Chewing Gum
CN101909605A (zh) * 2007-11-14 2010-12-08 皮埃蒙特医药品有限公司 制造用于药物递送的咀嚼剂型的方法及其产品
CN102238940A (zh) * 2008-12-05 2011-11-09 拜尔动物保健有限责任公司 含针状活性物质的挤出物

Also Published As

Publication number Publication date
JP2018162326A (ja) 2018-10-18
CA2906295C (en) 2019-01-22
EP2968569A1 (en) 2016-01-20
AU2023200668A1 (en) 2023-03-09
BR112015023435A8 (pt) 2019-12-03
EP2968569A4 (en) 2016-11-02
WO2014141223A1 (en) 2014-09-18
BR112015023435B1 (pt) 2022-05-03
US20150190417A1 (en) 2015-07-09
CA2906295A1 (en) 2014-09-18
AU2020277251A1 (en) 2020-12-24
CN105451771A (zh) 2016-03-30
CN111803465B (zh) 2023-05-09
JP2016512229A (ja) 2016-04-25
AU2014229179B2 (en) 2017-09-14
US20160184223A1 (en) 2016-06-30
AU2014229179A1 (en) 2015-10-08
JP6841799B2 (ja) 2021-03-10
AU2014229179C1 (en) 2018-09-27
AU2019203788A1 (en) 2019-06-20
BR112015023435A2 (pt) 2017-07-18
CN111803465A (zh) 2020-10-23
AU2017221825A1 (en) 2017-11-09
JP6378702B2 (ja) 2018-08-22
US9314478B2 (en) 2016-04-19
US9597285B2 (en) 2017-03-21

Similar Documents

Publication Publication Date Title
CN105451771B (zh) 可咀嚼配制物
US11679080B2 (en) Starch-free soft chew for veterinary applications
JP7412329B2 (ja) 経口用組成物及びその調製方法
TW202122077A (zh) 適口軟咀嚼物
CN114727622A (zh) 适口颗粒状兽用药组合物
WO2020234898A1 (en) Process for manufacturing soft chewable free flowing granules and companion animal products thereof
TW201806582A (zh) 製備用於投予動物之成形物件的方法
NZ763537A (en) Chewable formulation
NZ763537B2 (en) Chewable formulation
EP4507694A1 (en) Soft chewable veterinary dosage form
HK40079612A (en) Palatable soft-chew
HK40070267A (en) Palatable granular veterinary compositions

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20190712

Address after: Nishikiyo katsuoku

Applicant after: Argentina Innovation Co., Ltd.

Address before: Nishikiyo katsuoku

Applicant before: ARGENTA MFG LTD

Applicant before: Douglas Robert Cleverley

Applicant before: David Anthony Gill

Applicant before: Karen Davis

Applicant before: Priyanka Agava

Applicant before: Su .wen

Applicant before: Gopinat Devaragi

GR01 Patent grant
GR01 Patent grant