CN105451743B - 用于在活体中递送RNAi触发子至肿瘤细胞的聚偶联物 - Google Patents

用于在活体中递送RNAi触发子至肿瘤细胞的聚偶联物 Download PDF

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CN105451743B
CN105451743B CN201480044362.9A CN201480044362A CN105451743B CN 105451743 B CN105451743 B CN 105451743B CN 201480044362 A CN201480044362 A CN 201480044362A CN 105451743 B CN105451743 B CN 105451743B
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CN105451743A (zh
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承为军
S·黄
A·M·埃尔米达
D·B·罗泽玛
A·V·布罗金
J·C·卡尔森
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Arrowhead Pharmaceuticals Inc
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CN201480044362.9A 2013-08-07 2014-08-06 用于在活体中递送RNAi触发子至肿瘤细胞的聚偶联物 Active CN105451743B (zh)

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US201361863056P 2013-08-07 2013-08-07
US61/863,056 2013-08-07
PCT/US2014/049851 WO2015021092A1 (en) 2013-08-07 2014-08-06 Polyconjugates for delivery of rnai triggers to tumor cells in vivo

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US (3) US9487556B2 (https=)
EP (1) EP3030244B1 (https=)
JP (1) JP6433001B2 (https=)
KR (1) KR20160035081A (https=)
CN (1) CN105451743B (https=)
AU (1) AU2014306021B2 (https=)
CA (1) CA2919088A1 (https=)
EA (1) EA201690051A1 (https=)
IL (1) IL243941B (https=)
MX (1) MX2016001006A (https=)
SG (1) SG11201600379TA (https=)
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AR104754A1 (es) 2015-05-29 2017-08-09 Arrowhead Pharmaceuticals Inc Agentes de unión de tetrapéptido escindibles biológicamente
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SG11201600379TA (en) 2016-02-26
EP3030244B1 (en) 2021-04-21
EP3030244A1 (en) 2016-06-15
KR20160035081A (ko) 2016-03-30
AU2014306021A1 (en) 2016-01-28
US20190062748A1 (en) 2019-02-28
AU2014306021B2 (en) 2018-12-13
JP6433001B2 (ja) 2018-12-05
WO2015021092A1 (en) 2015-02-12
US20170022497A1 (en) 2017-01-26
US20150045573A1 (en) 2015-02-12
IL243941A0 (en) 2016-04-21
AU2014306021A2 (en) 2016-11-24
US9487556B2 (en) 2016-11-08
HK1220397A1 (zh) 2017-05-05
EP3030244A4 (en) 2017-06-28
TWI685347B (zh) 2020-02-21
TW201601742A (zh) 2016-01-16
IL243941B (en) 2019-06-30
EA201690051A1 (ru) 2016-06-30
CN105451743A (zh) 2016-03-30
JP2016535058A (ja) 2016-11-10
CA2919088A1 (en) 2015-02-12
MX2016001006A (es) 2016-04-19

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