CN105412338A - Blood-sugar-lowering medicinal liquor - Google Patents

Blood-sugar-lowering medicinal liquor Download PDF

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CN105412338A
CN105412338A CN201510838707.4A CN201510838707A CN105412338A CN 105412338 A CN105412338 A CN 105412338A CN 201510838707 A CN201510838707 A CN 201510838707A CN 105412338 A CN105412338 A CN 105412338A
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parasitic
wine
blood
medicated
viscum
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梁苑春
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Abstract

The invention relates to a blood-sugar-lowering medicinal liquor. The medicinal liquor is prepared from the following traditional Chinese medicinal materials including viscum averrhoa carambola, a Zanthoxyli radix, viscum emblic leafflower trees, viscum bombaxceiba, Japan bogorchid, viscum sand pear trees, viscum Cratoxylum cochinchinense, silkworm excrement, white paeony roots, dried rehmannia roots and viscum calamander. The blood-sugar-lowering medicinal liquor can treat both symptoms and root causes, performs comprehensive treatment, has the effects of clearing heat, quenching thirst, nourishing yin, tonifying spleen, clearing damp and calming the nerves, the medicinal materials are compatible so that dysphoria with smothery sensation is thoroughly eliminated, qi and blood can be nourished, and consumptive thirst caused by qi deficiency type secretion decrease, lung and kidney yin deficiency, kidney deficiency and stomach dryness evil can be treated, and the blood-sugar-lowering medicinal liquor is remarkable in treating effect on qi and yin deficiency type diabetes.

Description

A kind of hypoglycemic medicated wine
Technical field
The present invention relates to Chinese medicinal liquor field, be specifically related to a kind of hypoglycemic medicated wine and preparation method thereof.
Background technology
Diabetes are a kind of take hyperglycemia as the metabolic disease of feature caused by defect of insulin secretion and/or insulin action obstacle.Persistent high blood sugar and long-term metabolic are disorderly etc. can cause body tissue's organ, particularly eye, kidney, cardiovascular and neural infringement and dysfunction thereof and exhaustion.Severe patient can cause dehydration, the acute complications such as electrolyte disturbance and acid base imbalance ketoacidosis and Hyperosmotic coma.Diabetes are called " diabetes " by the traditional Chinese medical science." diabetes " this name of disease is just described in China's medical book Plain Questions of Huangdi's Internal Classic the earliest and Miraculous Pivot.The one-tenth Anttdisease Mechanism mainly ferritic deficiency of YIN of diabetes, the five internal organs are weak, multiple because of eating and drinking without temperance, surfeit delicious food, disorder of emotion, and labor for excessively, and causes deficiency of kidney-YIN, lung dryness of the stomach heat; Pathogenesis emphasis is that the deficiency of YIN is scorching, and is this with the deficiency of YIN, and scorching is mark; With the passing of time disease prolongs, deficiency of YIN affecting YANG, deficiency in both YIN and YANG; The deficiency of YIN is scorching, and consumption Tianjin liquid that burns makes blood viscous, and blood is not smooth forms the stasis of blood; Deficiency of YIN affecting YANG, yang deficiency cold coagulation, also can cause sun in blood stasis.
Blood sugar lowering and the sugared main means of control have two, and one is insulin injection, and two is drug administrations.Concerning type 1 diabetes, because self cannot excreting insulin, so to have no other way except insulin injection.Concerning type 2 diabetes mellitus, because self more or less can also excreting insulin, so there is simple medication to stimulate it secrete, there is an insulin injection, also have both to use with.Diabetes treatment by western medicine onset is rapid, but temporarily can only control the rising of blood glucose, cure the symptoms, not the disease, and the toxic and side effects brought is very large.As the infringement of liver function and renal function, what have even causes hepatic coma, and uremia is until threat to life.And although insulin injection reduces the generation of side effect and complication, can not eradicate, and it is high to there is cost, uses inconvenient shortcoming.This concept that Traditional Chinese Medicine does not have " blood glucose ", is one of presentation of diabetes (diabetes) at traditional Chinese medical science blood glucose height, is referred to as " mark ", and its reason is the result of dirty of each internal organs disorder imbalance, and this calls it " basis ".Chinese medicine has the advantage of oneself uniqueness in treatment diabetes: adopt Diabetes Mellitus Treated With Traditional Chinese Medicine to be not merely blood sugar lowering, focus on the comprehensive function of conditioning human body, overall recovery blood vessel elasticity, increase the histotrophic nutrition blood flow, particularly Chinese medicine such as the heart, liver, kidney, retina can overcome the hypoglycemic side effect that simultaneously produces of chemical synthetic drug or bring out the complication increased the weight of.Modern study shows, the mechanism of Diabetes Mellitus Treated With Traditional Chinese Medicine mainly contains the inhibitory action of alpha-glucosidase, the effect of para-insulin sample, helps to increase insulin secretion etc.
Alcoholic strength temperature and acrid in the mouth, Wen Zheneng cold relieving, Xin Zheneng disperses, so wine energy dredging the meridian, circulation of qi promoting and blood, exempt from numbness eliminating stagnation, warming YANG to expel cold, can dispersing the stagnated live-QI to relieve the stagnation of QI, a surname's feelings freely anticipate.Again because wine is the elite that corn is brewageed, therefore can also tonification the intestines and stomach." natural science will " carries: Wang Su, Zhang Heng, equal three people of horse emit mist row in morning.One people drinks, a human diet, and a people on an empty stomach.Empty stomach person is dead, and full trencherman is sick, and alcohol user is good for.This shows, and " wine gesture wards off evil, is better than effect that work eats also." combination of wine and medicine is the much progress of health preserving of drinking.Medicated wine is almost had to control the record of disease body-building bar none in the successive dynasties medicine works of China.Although the initial drinking behavior of the mankind can't be referred to as health preserving of drinking, there is close contacting with health care.Initial wine is that the wild fruit that the mankind gather obtains suitable condition natural fermentation remaining time; because many wild fruits inherently have medical value; so initial wine can deserve to be called natural " health promoting wine ", it has certain protection and facilitation to health.Today, along with the progress of science and technology, has developed into modernization meanses such as utilizing extraction, lixiviate and biological engineering from the basis of the traditional handicraft of Traditional Chinese medicinal wine, and the functional medicinal-liquor of high-load is made in the active ingredient of extracting in Chinese medicine.
Summary of the invention
The object of this invention is to provide a kind of hypoglycemic medicated wine.
The object of the invention is by following technical scheme realize:
Hypoglycemic medicated wine of the present invention is prepared from by the raw material comprising following weight portion:
Fructus Averrhoae Carambolae sets parasitic 10-30 part, brave 10-30 part of going up a hill, Radix Phytolaccae 5-20 part, the parasitic 10-30 part of phyllanthus emblica wood, the parasitic 30-50 part of silk cotton tree, Herba Rubi blinii 5-20 part, Nashi Pear set parasitic 30-50 part, the parasitic 10-30 part of cattle wood, Bombyx mori L. 5-20 part, Radix Paeoniae Alba 10-30 part, Radix Rehmanniae 5-20 part, the parasitic 10-30 part of kaki, 60-80% wine base 400-600 part.
Preferably, be prepared from by the raw material of following weight portion:
Fructus Averrhoae Carambolae sets parasitic 15-25 part, brave 15-25 part of going up a hill, Radix Phytolaccae 8-15 part, the parasitic 15-25 part of phyllanthus emblica wood, the parasitic 35-45 part of silk cotton tree, Herba Rubi blinii 8-15 part, Nashi Pear set parasitic 35-45 part, the parasitic 15-25 part of cattle wood, Bombyx mori L. 8-15 part, Radix Paeoniae Alba 15-25 part, Radix Rehmanniae 8-15 part, the parasitic 15-25 part of kaki, 70% wine base 500-550 part.
Below the crude drug source of the hypoglycemic medicated wine of the present invention:
Fructus Averrhoae Carambolae tree is parasitic, is the band stem branch and leaf of parasitic TaxillusChinensis (DC.) Danser of the parasitic platymiscium willow of the blunt fruit of Loranthaceae, parasitizes on Oxalidaceae plant carambola tree.Sour in the mouth, sweet, puckery, property is put down.Enter lung, stomach, large intestine channel.Clearing heat and expelling damp, reducing swelling and alleviating pain, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst, relieving dyspepsia.Control anemopyretic cold, and joint swells and ache, puerperal edema, xeropulmonary cough, acute gastroenteritis, carbuncle subcutaneous ulcer, toxic swelling and treating swelling and pain by traumatic injury.
Go up a hill tiger, root, stem, the leaf of Pittosporaceae plant sea gold PittosporumillicioidesMakino.Bitter in the mouth, pungent, warm in nature.Eliminating stasis to stop pain, promoting blood circulation and hemostasis, removing toxic substances and promoting subsidence of swelling.Dispelling the wind and dampness pathogens and rheumatoid arthritis, arthralgia pain, poliomyelitis sequela, puerperal paralysis, sciatica, toothache, stomachache, hypertension, asthma, traumatic injury, fracture, venom, furuncle, allergic dermatitis.
Radix Phytolaccae is the Herb of Gesneriaceae thing Guangxi awns hair lettuce tongue.Cough-relieving; Pain relieving.Main cough; Sciatica; Arthritis.
Phyllanthus emblica wood is parasitic, is the band stem branch and leaf of Loranthaceae Loranthus plant oil tea LoranthusSmnpsoniiHance, to parasitize more than euphorbia plant on mandarin orange tree.Sweet, micro-puckery, cool in nature.Enter lung, liver, kidney channel.Relieving sore-throat by clearing away heat, moistening the lung and resolving phlegm.Diuresis, blood pressure lowering.Treating acute and chronic pharyngolaryngitis, lung-heat chronic cough, hypertension, uterus rub rotten, cervical cancer.
Silk cotton tree is parasitic, is the band stem branch and leaf of Loranthaceae Loranthus plant five lobe Herba Taxilli LoranthuspentapetalusRoxb..Parasitize in Bombacaceae Gossampinus plant silk cotton tree.Another name: heroic tree is parasitic, parasitic through cotton, speckle branch spends parasitism, Flos Bombacis Malabarici parasitism, Flos Bombacis Malabarici is parasitic.Sweet, light, cool.Enter lung, spleen, large intestine channel.Heat-clearing and toxic substances removing, damp eliminating is subsided a swelling, and the lung that disappears reduces phlegm, bowel relieving dysentery relieving, hemostasis, antitumor.Control pulmonary tuberculosis.
Herba Rubi blinii, the root of moraceae plants ficus simplicissima FicussimplicissimaLour..Sweet in the mouth, slightly warm in nature.Invigorating the spleen for eliminating dampness, promoting the circulation of QI to relieve pain, relaxing muscles and tendons and activating QI and blood in the collateral, preventing phlegm from forming and stopping coughing, tonifying the lung lactogenesis.
Nashi Pear tree is parasitic, is the dry stem and branch with leaf of Loranthaceae Loranthus plant Herba Taxilli Loranthusparasiticus (L.) Merr..Parasitize on rosaceous plant Nashi Pear tree.Puckery, cool.Enter lung, stomach, Liver Channel.Promoting the production of body fluid to quench thirst, removing heat-phlegm, nourishing the lung to arrest cough, lowering the adverse-rising QI to subdue asthma.Control dryness of the lung heat cough, asthma, metrorrhagia, cough expectorant holds blood under the arm.
Cattle wood is parasitic, is the band stem branch and leaf of parasitic TaxillusSuichuensis (Lecomte) Danser in the parasitic platymiscium Sichuan of the blunt fruit of Loranthaceae, parasitizes on Hypericaceae plant cattle wood.Sweet in the mouth, light, micro-hardship, cool in nature.Enter lung, spleen, Liver Channel.Clearing away summer-heat, reducing swelling and alleviating pain, evil-wind expelling and dampness removing, dysentery relieving antidiarrheal.Cure cold, heatstroke, beriberoid pyretic arthralgia, damp-heat dysentery, jaundice, cough due to lung-heat, traumatic injury.
Bombyx mori L. is the dry feces of Bombycidae animal bombyx mori larva.Sweet in the mouth; Pungent; Warm in nature.Liver; Spleen; Stomach warp.Expelling wind and removing dampness; Regulating the function of the stomach to resolve the turbidity; Promoting blood circulation to restore menstrual flow.Main air pain of dampness syndrome; Limbs are unsuccessful; Rubella pruritus; Vomit and diarrhoea and have a cramp; Amenorrhea; Metrorrhagia
The Radix Paeoniae Alba is the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Bitter, sour, be slightly cold.Return liver, spleen channel.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
The Radix Rehmanniae is the fresh of scrophulariaceae rehmannia glutinosa plant RehmanniaglutinosaLibosch. or dried root, is slowly cured by Radix Rehmanniae to about most probably dry.Sweet, cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.
Kaki is parasitic, is the stem and branch with leaf of Loranthaceae plant ebonyshoot mistletoe branchlet and leaf.Bitter; Property is put down.Liver; Lung; Stomach warp.Wind-damp dispelling; Bone and muscle strengthening; Cough-relieving; Detumescence; Blood pressure lowering.Main air pain of dampness syndrome; Waist and leg ache; Cough; Spitting of blood; Stomachache; Frequent fetal movement; Furuncle; Hypertension.
Wine, warm in nature and acrid in the mouth, Wen Zheneng cold relieving, Xin Zheneng disperses, so wine energy dredging the meridian, circulation of qi promoting and blood, exempt from numbness eliminating stagnation, warming YANG to expel cold, can dispersing the stagnated live-QI to relieve the stagnation of QI, a surname's feelings freely anticipate.Again because wine is the elite that corn is brewageed, therefore can also tonification the intestines and stomach.
Another aspect of the present invention there is provided the preparation method of the hypoglycemic medicated wine of the present invention:
(1) get whole medical material, clean, sterilizing, drying, chopping;
(2) medical material after chopping adds wine base and soaks 50-70 days;
(3) gained medicated liquor will be soaked filter, obtain filtrate;
(4) filtrate add water and rice wine be deployed into 800-1500 part, wine degree is 30-50%;
(5) deployed medicated liquor filters after naturally clarifying;
(6) wine liquid after filtering stores 5-10 days, obtains described medicated wine.
The preparation method of the hypoglycemic medicated wine of the present invention is preferably as follows:
(1) get whole medical material, clean, sterilizing, drying, chopping;
(2) medical material after chopping adds crystal sugar and wine base soaks 60 days;
(3) gained medicated liquor will be soaked filter, obtain filtrate;
(4) filtrate add water and rice wine be deployed into 1000 parts, wine degree is 40-45%;
(5) deployed medicated liquor filters after naturally clarifying;
(6) wine liquid after filtering stores 7 days, obtains described medicated wine.
Diabetes, the traditional Chinese medical science is called diabetes, rises because spleen loses transporting, kidney loses Gu Na, lung loses defeated cloth.Diabetes are generally divided into intense heat due to deficiency of YIN type, type of deficiency of both QI and YIN regulating YIN and YANG deficiency by the traditional Chinese medical science.(1) intense heat due to deficiency of YIN: show as excessive thirst polydipsia, dry pharynx dryness of the tongue, polyphagia polyphagia, red constipation of urinating, red tongue with a little fluid yellow fur, slippery and rapid pulse or stringy and rapid pulse.Employing replenishing YIN and removing heat is treated.(2) deficiency of both QI and YIN: show as weak, breathe hard, spontaneous perspiration, dynamic then increase the weight of, dry mouth and tougue, polydipsia polyuria, dysphoria with feverish sensation in the chest palms and soles, constipation, soreness of the waist and knees, light red tongue or red tongue dark, indentations at the margin of the tongue, the few Tianjin of white and thin fur, or few tongue, thready and weak pulse.Adopt treatment for tonifying Qi and nourishing Yin.(3) deficiency of both YIN and YANG: show as weak spontaneous perspiration, coldness of the body with chills, soreness of the waist and knees, helix parch, polydipsia polyuria, or edema oliguria, or diarrhea before dawn, impotence and premature ejaculation, pale tongue with white fur, deep,thready and forceless pulse.Adopt the treatment of warming YANG nourishing YIN.
Fructus Averrhoae Carambolae of the present invention is set parasitic relieving restlessness and is quenched the thirst, clearing heat and expelling damp; To go up a hill tiger, Radix Phytolaccae promoting blood circulation to remove blood stasis, removing toxic substances pain relieving; The parasitic clearing heat and moistening lung of phyllanthus emblica wood, antihypertensive diuretic; Silk cotton tree is parasitic, Nashi Pear sets parasitic clearing heat and relieving fidgetness, promoting the production of body fluid to quench thirst; Herba Rubi blinii invigorating the spleen for eliminating dampness, circulation of qi promoting lung moistening; The parasitic reducing swelling and alleviating pain of cattle wood, evil-wind expelling and dampness removing; Bombyx mori L. regulating the function of the stomach to resolve the turbidity, expelling wind and removing dampness; The pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating; Radix Rehmanniae clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid; The parasitic Yishen Jiangya of kaki.Full side works in coordination with mutually, plays altogether and relieves heat and thirst, YIN nourishing spleen invigorating, the merit that damp eliminating is calmed the nerves, each medicine mutually 5, and dysphoria with smothery sensation is dispelled to the greatest extent, and QI and blood is given birth to and brought up, and controls gas not cloth Tianjin, deficiency of YIN of both the lung and kidney, the quenching one's thirst of dryness of the stomach of suffering from a deficiency of the kidney.Be used for the treatment of the diabetes Be very effective of deficiency of both QI and YIN.
The hypoglycemic medicated wine of one provided by the invention has the following advantages:
1, hypoglycemic medicated wine energy treating both the principal and secondary aspects of a disease provided by the invention, looks after comprehensively, has and relieve heat and thirst, YIN nourishing spleen invigorating, the merit that damp eliminating is calmed the nerves, each medicine mutually 5, and dysphoria with smothery sensation is dispelled to the greatest extent, and QI and blood is given birth to and brought up, and controls gas not cloth Tianjin, deficiency of YIN of both the lung and kidney, the quenching one's thirst of dryness of the stomach of suffering from a deficiency of the kidney.Be used for the treatment of the diabetes Be very effective of deficiency of both QI and YIN.
2, clinical observation shows, with the use of the consumption of insulin while using the present invention's treatment, compared with consumption when being used alone insulinize, there is pole significant difference (P<0.01), illustrate that Chinese medicine composition of the present invention has remarkable hypoglycemic activity to type of deficiency of both QI and YIN diabetes patient, insulin-dependent patient is had to the effect significantly reducing its insulin dosage.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.
embodiment 1
Fructus Averrhoae Carambolae sets parasitic 10g, the parasitic 10g of the brave 10g that goes up a hill, Radix Phytolaccae 5g, phyllanthus emblica wood, silk cotton tree parasitic 30g, Herba Rubi blinii 5g, Nashi Pear set parasitic 30g, cattle wood parasitic 10g, Bombyx mori L. 5g, Radix Paeoniae Alba 10g, Radix Rehmanniae 5g, the parasitic 10g of kaki.Get whole medical material, clean, sterilizing, drying, chopping, be that 60% wine base 400g soaks 50 days with alcoholic strength, soak gained medicated liquor and filter, get filtrate and to add water and rice wine is deployed into 800g, rectification degree is 30%, deployed medicated liquor squeezes into semi-finished product cylinder, and naturally filter after clarification, the wine liquid after filtration stores 5 days, obtain described medicated wine, fill after inspection.
embodiment 2
Fructus Averrhoae Carambolae sets parasitic 30g, the parasitic 30g of the brave 30g that goes up a hill, Radix Phytolaccae 20g, phyllanthus emblica wood, silk cotton tree parasitic 50g, Herba Rubi blinii 20g, Nashi Pear set parasitic 50g, cattle wood parasitic 30g, Bombyx mori L. 20g, Radix Paeoniae Alba 30g, Radix Rehmanniae 20g, the parasitic 30g of kaki.Get whole medical material, clean, sterilizing, drying, chopping, be that 80% wine base 600g soaks 70 days with alcoholic strength, soak gained medicated liquor and filter, get filtrate and to add water and rice wine is deployed into 1500g, rectification degree is 60%, deployed medicated liquor squeezes into semi-finished product cylinder, and naturally filter after clarification, the wine liquid after filtration stores 10 days, obtain described medicated wine, fill after inspection.
embodiment 3
Fructus Averrhoae Carambolae sets parasitic 25g, the parasitic 25g of the brave 25g that goes up a hill, Radix Phytolaccae 15g, phyllanthus emblica wood, silk cotton tree parasitic 45g, Herba Rubi blinii 15g, Nashi Pear set parasitic 45g, cattle wood parasitic 25g, Bombyx mori L. 15g, Radix Paeoniae Alba 25g, Radix Rehmanniae 15g, the parasitic 25g of kaki.Get whole medical material, selected, cleaning, sterilizing, drying, chopping, adding crystal sugar 40g, is that 70% wine base 500g soaks 60 days with alcoholic strength, soak gained medicated liquor to filter, get filtrate add water and rice wine be deployed into 1000g, rectification degree is 40%, and deployed medicated liquor squeezes into semi-finished product cylinder, naturally filter after clarification, wine liquid after filtration stores 7 days, obtains described medicated wine, carries out fill after inspection.
embodiment 4
Fructus Averrhoae Carambolae sets parasitic 15g, the parasitic 15g of the brave 15g that goes up a hill, Radix Phytolaccae 8g, phyllanthus emblica wood, silk cotton tree parasitic 35g, Herba Rubi blinii 8g, Nashi Pear set parasitic 35g, cattle wood parasitic 15g, Bombyx mori L. 8g, Radix Paeoniae Alba 15g, Radix Rehmanniae 8g, the parasitic 15g of kaki.Get whole medical material, selected, cleaning, sterilizing, drying, chopping, adding crystal sugar 60g, is that 70% wine base 550kg soaks 60 days with alcoholic strength, soak gained medicated liquor to filter, get filtrate add water and rice wine be deployed into 1000g, rectification degree is 45%, and deployed medicated liquor squeezes into semi-finished product cylinder, naturally filter after clarification, wine liquid after filtration stores 7 days, obtains described medicated wine, fill after inspection.
embodiment 5
Fructus Averrhoae Carambolae sets parasitic 20g, the parasitic 20g of the brave 20g that goes up a hill, Radix Phytolaccae 10g, phyllanthus emblica wood, silk cotton tree parasitic 40g, Herba Rubi blinii 10g, Nashi Pear set parasitic 40g, cattle wood parasitic 20g, Bombyx mori L. 10g, Radix Paeoniae Alba 20g, Radix Rehmanniae 10g, the parasitic 20g of kaki.Get whole medical material, selected, cleaning, sterilizing, drying, chopping, adding crystal sugar 50g, is that 70% wine base 450kg soaks 60 days with alcoholic strength, soak gained medicated liquor to filter, get filtrate add water and rice wine be deployed into 1000g, rectification degree is 42%, and deployed medicated liquor squeezes into semi-finished product cylinder, naturally filter after clarification, wine liquid after filtration stores 7 days, obtains described medicated wine, fill after inspection.
clinical trial
1 inclusive criteria
1.1 allly have thirsty polydipsia, rapid digestion of food easily hungry, frequent micturition and sweet, body is gradually shown in that patient of becoming thin can be diagnosed as diabetes (diabetes).
1.2 all fatigue and weakness, spontaneous sweating, lazy speech of breathing hard, thirst and liking drink, dysphoria with feverish sensation in the chest palms and soles, palpitation and insomnia, red constipation of urinating, red tongue with a little fluid, corpulent tongue are large, thin fur or flower are shelled, and stringy and thready pulse or number person, be Qi and Yin deficiency diabetes mellitus.
1.3 have diabetic symptom, any time blood glucose > 11.1mmol/L or fasting glucose > 7.0mmol/L.
1.4 are defined as type 2 diabetes mellitus, the patient of long-term taking metformin or the patient of long term injections insulin.
All patients all meet more than 1 or 1 in above-mentioned 4
2 case selections
2.1 allly meet above-mentioned doctor trained in Western medicine criteria for classification, TCM syndrome diagnostic criteria patient simultaneously;
2.2 20-66 age, persons year;
2.3 are ready acceptance 2 weeks therapists;
2.4 signatures enter clinical research Informed Consent Form person.
3 medicines and grouping
Comparative example group: insulin
Test example group: embodiment 6 granules+insulin
4 observation indexs: the situation of change of observing main clinic symptoms and sign, empty stomach and after the meal 2 hours blood glucoses detect; The reduction of insulin dosage.
5 Therapeutic Method:
Must check that mean blood glucose be fasting glucose > 7.0mmol/L for 3 times continuously before 5.1 beginning administrations, post-prandial glycemia is > 11.1mmol/L.The 60 routine clothes for patients the meeting group standard Chinese medicine and western medicine of other any blood sugar lowering of must stopping using before carrying out clinical trial.
30 routine patients of 5.2 comparative example groups continue with insulin; The routine clothes for patients embodiment 5 of test example group 30, each 15ml, every day 1 time, 30 minutes ante cibum are oral, within 1 month, are 1 course for the treatment of, and therapeutic process controls blood glucose in critical field with the use of insulin.
5.3 therapeutic processes strictly carry out dietetic therapy.
6 results: test group patient declines gradually at about 4 weeks blood glucose of taking medicine, and insulin use amount gradually reduces, blood sugar reducing function is steady, and show the observation of safety indexes, medicine of the present invention has no adverse reaction.After clinical treatment, each group patient insulin consumption is in table 1.
Table 1: after treatment insulin dosage (`x ± s) (n=30)
Clinical grouping Insulin dosage
Test example group 22±2.5U *
Comparative example group 48±2.1U
Note: compared with comparative example group, * P<0.01.
Result shows: with the use of the consumption of insulin while using the present invention's treatment, compared with consumption when being used alone insulinize, there is pole significant difference (P<0.01), illustrate that Chinese medicine composition of the present invention has remarkable hypoglycemic activity to type of deficiency of both QI and YIN diabetes patient, insulin-dependent patient is had to the effect significantly reducing its insulin dosage.
Model case:
Case 1: Liu xx, female, 41 years old.Main cause is thirsty, polydipsia, weak more than 4 years.Spirit depressing before 4 years and feel thirsty gradually, polydipsia, weak.Go to a doctor to local hospital, look into fasting glucose 8.7mmol/L, be diagnosed as " diabetes ", give the embodiment of the present invention 3 medicated wine 15ml/ day, after 20 days, symptom alleviates gradually, and blood glucose declines.Rule takes medicated wine of the present invention always afterwards, and Morbidity control is comparatively steady.
Although above with general explanation, detailed description of the invention and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.

Claims (4)

1. a hypoglycemic medicated wine, it is characterized in that being prepared from by the raw material of following weight portion: Fructus Averrhoae Carambolae sets parasitic 10-30 part, brave 10-30 part of going up a hill, Radix Phytolaccae 5-20 part, the parasitic 10-30 part of phyllanthus emblica wood, the parasitic 30-50 part of silk cotton tree, Herba Rubi blinii 5-20 part, Nashi Pear set parasitic 30-50 part, the parasitic 10-30 part of cattle wood, Bombyx mori L. 5-20 part, Radix Paeoniae Alba 10-30 part, Radix Rehmanniae 5-20 part, the parasitic 10-30 part of kaki, 60-80% wine base 400-600 part.
2. hypoglycemic medicated wine as claimed in claim 1, it is characterized in that being prepared from by the raw material of following weight portion: Fructus Averrhoae Carambolae sets parasitic 15-25 part, brave 15-25 part of going up a hill, Radix Phytolaccae 8-15 part, the parasitic 15-25 part of phyllanthus emblica wood, the parasitic 35-45 part of silk cotton tree, Herba Rubi blinii 8-15 part, Nashi Pear set parasitic 35-45 part, the parasitic 15-25 part of cattle wood, Bombyx mori L. 8-15 part, Radix Paeoniae Alba 15-25 part, Radix Rehmanniae 8-15 part, the parasitic 15-25 part of kaki, 70% wine base 500-550 part.
3. hypoglycemic medicated wine as claimed in claim 1 or 2, is characterized in that it is prepared from by the following method:
Get whole medical material, clean, sterilizing, drying, chopping;
Medical material after chopping adds wine base and soaks 50-70 days;
Gained medicated liquor will be soaked filter, obtain filtrate;
Filtrate adds water and rice wine is deployed into 800-1500 part, and wine degree is 30-50%;
Deployed medicated liquor filters after naturally clarifying;
Wine liquid after filtration stores 5-10 days, obtains described medicated wine.
4. hypoglycemic medicated wine as claimed in claim 1 or 2, is characterized in that it is prepared from by the following method:
Get whole 9 medical materials, clean, sterilizing, drying, chopping;
Medical material after chopping adds crystal sugar and wine base soaks 60 days;
Gained medicated liquor will be soaked filter, obtain filtrate;
Filtrate adds water and rice wine is deployed into 1000 parts, and wine degree is 40-45%;
Deployed medicated liquor filters after naturally clarifying;
Wine liquid after filtration stores 7 days, obtains described medicated wine.
CN201510838707.4A 2015-11-27 2015-11-27 Blood-sugar-lowering medicinal liquor Pending CN105412338A (en)

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