CN105412319A - Traditional Chinese medicine preparation for treating chronic kidney failure and preparation method and application thereof - Google Patents
Traditional Chinese medicine preparation for treating chronic kidney failure and preparation method and application thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating chronic kidney failure and a preparation method and application thereof. The traditional Chinese medicine preparation is prepared from, by mass, 15-26 parts of milkvetch roots, 8-15 parts of rhodotypos scandens and 2-5 parts of pepper; the preparation method comprises the steps that the pepper is taken and stir-fried to brown, the fried pepper is ground into fine powder and sieved, and pepper powder is obtained; the rhodotypos scandens is taken, vinegar liquid and water are added to be mixed to be uniform, braising is conducted for a while, frying is conducted with mild fire to be not sticky, the processed rhodotypos scandens is taken out for drying, ground into fine powder and sieved, and rhodotypos scandens powder is obtained; the milkvetch roots are immersed in rice wine for a period of time and then taken out for drying, the dried milkvetch roots are stir-fried with the mild fire, ground into fine powder and sieved, and milkvetch root powder is obtained; the pepper powder, the rhodotypos scandens powder and the milkvetch root powder are mixed, and pills are prepared. According to the traditional Chinese medicine preparation for treating the chronic kidney failure, the compatibility is scientific, the effects of invigorating Qi for strengthening superficies, supporting body resistance, invigorating Qi to nourish the blood, warming the kidney, enhancing Yang, tonifying the spleen and dissolving the turbidity are achieved, and the traditional Chinese medicine preparation has the advantages of being significant in effect, exact in drug efficacy and quick in effect for the symptoms, caused by the chronic kidney failure, of metabolite retention, imbalance of water, electrolyte and acid-base equilibrium, involvement of all systems of a whole body and the like.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically a kind of Chinese medicine preparation for the treatment of chronic renal failure and preparation method thereof and application.
Background technology
Chronic renal failure is also known as chronic renal insufficiency, refer to the chronic progressive external Renal lesion that a variety of causes causes, cause the obvious atrophy of kidney, its basic function can not be maintained, clinical appearance is with metabolite retention, water, electrolyte, acid base imbalance, each system involvement of whole body is the clinical syndrome of main manifestations, also referred to as uremia.From protopathy onset to renal insufficiency, can be the several years interval time to more than ten years.Chronic renal failure is the severe stage of renal insufficiency.
The cause of disease of chronic renal failure accounts for first place with various constitutional and secondary glomerulonephritis, secondly be congenital urinary system malformation, common with renal arteriolosclerosis, hypertension, connective tissue disease etc. in general systemic disease, in recent years, the protopathy of chronic renal failure changes to some extent, renal interstitial tubule damages the chronic renal failure caused and is also subject to people's attention gradually, and the chronic renal failure that diabetic nephropathy, autoimmunity and connective tissue disease renal damage cause is also on the rise.
Chronic renal failure has influence on each organs and systems, can cause diversified clinical manifestation.Chronic renal failure mainly causes water late period, electrolyte, acid base imbalance, sugar, fat, protein, disorder of amino acid catabolism and the clinical pathological changes of each system dysfunction.
The Therapeutic Method of chronic renal failure comprises medical treatment, dialysis therapy and renal transplantation.Dialysis therapy and renal transplantation are undoubtedly end-stage renal failure patient optimal treatment and select, but because these therapies are expensive and supply kidney derived limited often not by most of patient is accepted.Some Patients With Kidney Diseases, before advancing to end-stage renal failure, by rational herbal treatment, can delay the progress of its course advancement, much can reverse completely, therefore, should pay attention to the treatment by Chinese herbs of chronic renal failure.
Pericarpium Zanthoxyli, call fragrant green pepper, large Pericarpium Zanthoxyli, Semen zanthoxyli, for the dry mature skin (Pericarpium Zanthoxyli) of rutaceae Capsicum annuum L. (fragrant green pepper, Zanthoxylum schinifolium, Pericarpium Zanthoxyli, Canis familiaris L. green pepper) or Pericarpium Zanthoxyli (another name for Sichuan Province green pepper, Fructus Zanthoxyli, Capsicum tetragonum, pericarpium zanthoxyli bungeani, Radix Campylotropis Hirtella (Herba Myrsines Africanae)) and seed (Semen zanthoxyli) are used as medicine.Warm in nature, acrid in the mouth, returns spleen, stomach, kidney channel, has effect of warming middle-JIAO to relieve pain, killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.
Summary of the invention
The object of the present invention is to provide that a kind of Be very effective, drug effect are definite, the Chinese medicine preparation of the treatment chronic renal failure of quick result and preparation method thereof and application.
For achieving the above object, the invention provides following technical scheme:
Treat a Chinese medicine preparation for chronic renal failure, be made up of the raw material of following mass parts: the Radix Astragali 15 ~ 26 parts, Fructus Rhodotyporis scandentis 8 ~ 15 parts, 2 ~ 5 parts, Pericarpium Zanthoxyli.
As the further scheme of the present invention: be made up of the raw material of following mass parts: the Radix Astragali 18 ~ 22 parts, Fructus Rhodotyporis scandentis 10 ~ 14 parts, 3 ~ 5 parts, Pericarpium Zanthoxyli.
As the further scheme of the present invention: be made up of the raw material of following mass parts: the Radix Astragali 20 parts, Fructus Rhodotyporis scandentis 12 parts, 4 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 ~ 250 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 3 ~ 4 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
The using method of the Chinese medicine preparation of described treatment chronic renal failure is: every day 3 times, early, middle and late each 1 time, each taking dose is equivalent to the dosage of 12g crude drug amount, warm water delivery service in half an hour after meal, it within 10 days, is 1 course for the treatment of, take 3 ~ 4 courses for the treatment of continuously can fully recover, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
The application of described Chinese medicine preparation in the medicine of preparation treatment chronic renal failure.
Compared with prior art, the invention has the beneficial effects as follows: Chinese medicine preparation compatibility science of the present invention, with invigorating QI to consolidate the body surface resistance, the Radix Astragali of diuresis poison holding is principal agent, with the Fructus Rhodotyporis scandentis of Buxue Yishen and warming middle-JIAO to relieve pain, the Pericarpium Zanthoxyli of killing parasites for relieving itching is accessory drugs, three taste medical materials play invigorating QI to consolidate the body surface resistance jointly, the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, warming the kidney to activate YANG, the effect that spleen invigoratingization is turbid, for the metabolite retention caused by chronic renal failure, water, electrolyte, acid base imbalance, the symptoms such as each system involvement of whole body have Be very effective, drug effect is definite, the advantage of quick result, the clinical treatment of chronic renal failure can be widely used in.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of Chinese medicine preparation for the treatment of chronic renal failure, is made up of the raw material of following mass parts: the Radix Astragali 26 parts, Fructus Rhodotyporis scandentis 8 parts, 2 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 3 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
Embodiment 2
In the embodiment of the present invention, a kind of Chinese medicine preparation for the treatment of chronic renal failure, is made up of the raw material of following mass parts: the Radix Astragali 15 parts, Fructus Rhodotyporis scandentis 15 parts, 5 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 3 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
Embodiment 3
In the embodiment of the present invention, a kind of Chinese medicine preparation for the treatment of chronic renal failure, is made up of the raw material of following mass parts: the Radix Astragali 22 parts, Fructus Rhodotyporis scandentis 10 parts, 3 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 4 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
Embodiment 4
In the embodiment of the present invention, a kind of Chinese medicine preparation for the treatment of chronic renal failure, is made up of the raw material of following mass parts: the Radix Astragali 18 parts, Fructus Rhodotyporis scandentis 14 parts, 5 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 4 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
Embodiment 5
In the embodiment of the present invention, a kind of Chinese medicine preparation for the treatment of chronic renal failure, is made up of the raw material of following mass parts: the Radix Astragali 20 parts, Fructus Rhodotyporis scandentis 12 parts, 4 parts, Pericarpium Zanthoxyli.
The preparation method of the Chinese medicine preparation of described treatment chronic renal failure, comprises the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 250 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 4 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
Chinese medicine preparation compatibility science of the present invention, there is the effect that invigorating QI to consolidate the body surface resistance, the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, warming the kidney to activate YANG, spleen invigoratingization are turbid, for the metabolite retention caused by chronic renal failure, water, electrolyte, acid base imbalance, the symptoms such as each system involvement of whole body have that Be very effective, drug effect are definite, the advantage of quick result, can be widely used in the clinical treatment of chronic renal failure.
Animal acute toxicity test
Now animal acute toxicity test is carried out to Chinese medicine preparation of the present invention, get Mouse and rat half and half, be divided into five groups, respectively the oral Chinese medicine preparation/kg (more than 20 times of this dosage behaviour taking dose) being equivalent to embodiment 1 ~ 5 preparation of 20g crude drug amount, once a day, 7 days are continued.To observation post administration 2 weeks, do not have Mouse and rat dead, show that the toxicity of Chinese medicine preparation of the present invention is very micro-.Therefore, clinical trial is carried out to the patient being diagnosed as chronic renal failure.
It is below the clinical research data of Chinese medicine preparation treatment chronic renal failure of the present invention
1, case selection
Choose patients of chronic renal failure 400 example made a definite diagnosis and carry out clinical observation, wherein male 231 example, women 169 example, 21 ~ 74 years old age, 49 years old mean age, the course of disease 5 months ~ 20 years, average course of disease 6 years.This 400 routine patient is divided at random treatment 1 ~ 5 group, contrast 1 ~ 3 group totally eight groups, often organize 50 examples, the course of disease, the degrees of symptoms of the case between each group are basically identical, without significant difference, have comparability.
2, Therapeutic Method
Treat 1 ~ 5 group and take the obtained pill of the embodiment of the present invention 1 ~ 5 respectively, every day 3 times, early, middle and late each 1 time, each taking dose is equivalent to the dosage of 12g crude drug amount, warm water delivery service in half an hour after meal, within 10 days, be 1 course for the treatment of, taking 3 ~ 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Contrast 1 group to take nephritis and to relax sheet, by specification use, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Contrast 2 groups of pills taken only containing the Radix Astragali and Fructus Rhodotyporis scandentis, all the other are identical with embodiment 5.Every day 3 times, early, middle and late each 1 time, each taking dose is equivalent to the dosage of 12g crude drug amount, warm water delivery service in half an hour after meal, within 10 days, is 1 course for the treatment of, and taking 3 ~ 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Contrast 3 groups of pills taken only containing Pericarpium Zanthoxyli, all the other are identical with embodiment 5.Every day 3 times, early, middle and late each 1 time, each taking dose is equivalent to the dosage of 12g crude drug amount, warm water delivery service in half an hour after meal, within 10 days, is 1 course for the treatment of, and taking 3 ~ 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, curative effect determinate standard
(1) cure: the transference cures such as anemia, edema, oliguria, anuria, nausea,vomiting,diarrhea, body constitution strengthens, and with it energetically, health is fully recovered;
(2) effective: above-mentioned symptom is alleviated to some extent;
(3) invalid: disease is unchanged.
4, therapeutic outcome
The comparitive study that table 1 is respectively organized
Through the treatment of 3 ~ 4 courses for the treatment of, the curative effect of each group is as shown in table 1: select the cure rate of the treatment group of Chinese medicine preparation of the present invention to be 70 ~ 74%, total effective rate is 90 ~ 94%; The cure rate contrasting 1 group is 28%, and total effective rate is 58%; Contrast the cure rate of 2 ~ 3 groups and total effective rate all well below treatment 5 groups, especially the curative effect that 2 groups and the contrast cure rate of 3 groups and total effective rate sum are still significantly less than treatment 5 groups is contrasted, illustrate that Chinese medicine preparation of the present invention just has so high cure rate and total effective rate under the mutual compatibility effect of each raw material, Chinese medicine preparation of the present invention is applicable to the treatment of chronic renal failure.
5, model case
Case 1: journey, female, 42 years old, suffer from chronic glomerulonephritis 8 years, in recent years, hydrouria, night more so.On inspection, chronic renal failure is diagnosed as.After taking the embodiment of the present invention 5 obtained 3 courses for the treatment of of pill, above-mentioned symptom disappears completely, and livelihood restoration is normal, thoroughly cures.
Case 2: Feng, man, 68 years old, patient because of occur weak, breathe hard, the symptom such as two lower limbs edema goes to a doctor, there are indentation, white and thin fur in white, the pale tongue of complexion light, limit on inspection, and soft pulse is soft, and differential diagnosis in tcm is edema due to YANG-insufficiency.Have a medical check-up and be diagnosed as diabetic nephropathy, chronic renal failure.After taking the embodiment of the present invention 5 obtained 2 courses for the treatment of of pill, above-mentioned symptom all disappears, and physical recovery is normal, and recovery from illness is not recurred so far.
Case 3: tall certain, female, 38 years old, patient previously had more than 2 years of hypertension history, because occurring that dizziness, the soreness of waist, face and the symptom such as edema of pair of lower extremities, nausea and vomiting are medical, on inspection, was diagnosed as chronic renal failure.After taking the embodiment of the present invention 5 obtained 4 courses for the treatment of of pill, above-mentioned symptom disappears, and follows up a case by regular visits to recurrence, thoroughly cures.
Case 4: Zhu, man, 56 years old, patient previously had chronic glomerulonephritis medical history, because the symptoms such as weak, tachypnea are gone to a doctor, shortness of breath and low voice on inspection, pale complexion, the dark red white and thin fur of tongue, deep-thready pulse, dialectical for accumulateing in deficiency of spleen-YANG and kidneyYANG, turbid damp.The two renal atrophy of B ultrasonic display, is diagnosed as chronic renal failure.After taking the embodiment of the present invention 5 obtained 3 courses for the treatment of of pill, above-mentioned symptom thoroughly disappears, and follows up a case by regular visits to without recurrence, thoroughly cures.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (5)
1. treat a Chinese medicine preparation for chronic renal failure, it is characterized in that, be made up of the raw material of following mass parts: the Radix Astragali 15 ~ 26 parts, Fructus Rhodotyporis scandentis 8 ~ 15 parts, 2 ~ 5 parts, Pericarpium Zanthoxyli.
2. the Chinese medicine preparation for the treatment of chronic renal failure according to claim 1, is characterized in that, is made up of the raw material of following mass parts: the Radix Astragali 18 ~ 22 parts, Fructus Rhodotyporis scandentis 10 ~ 14 parts, 3 ~ 5 parts, Pericarpium Zanthoxyli.
3. the Chinese medicine preparation for the treatment of chronic renal failure according to claim 1, is characterized in that, is made up of the raw material of following mass parts: the Radix Astragali 20 parts, Fructus Rhodotyporis scandentis 12 parts, 4 parts, Pericarpium Zanthoxyli.
4., according to the preparation method of the Chinese medicine preparation of the arbitrary described treatment chronic renal failure of claims 1 to 3, it is characterized in that, comprise the following steps:
(1) get Pericarpium Zanthoxyli, use slow fire parching to brown, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains Zanthoxyli Bungeani powder, for subsequent use;
(2) get Fructus Rhodotyporis scandentis, mix thoroughly with vinegar liquid and water, slightly stewing, fry with slow fire and take out dry to tack-free for spending, grind into powder, cross 180 ~ 250 mesh sieves, obtain Fructus Rhodotyporis scandentis powder, for subsequent use;
(3) Radix Astragali is immersed yellow wine 3 ~ 4 hours, after taking-up, dry, pour in pot, slow fire parch, taking-up cools, and grinds into powder, crosses 250 mesh sieves, obtains astragalus membranaceus powder, for subsequent use;
(4) astragalus membranaceus powder of the Fructus Rhodotyporis scandentis powder of the Zanthoxyli Bungeani powder of step (1), step (2) and step (3) is mixed, make pill, be the Chinese medicine preparation of described treatment chronic renal failure.
5. the application of the Chinese medicine preparation as described in as arbitrary in claims 1 to 3 in the medicine of preparation treatment chronic renal failure.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111819444A (en) * | 2018-03-02 | 2020-10-23 | 赢创运营有限公司 | In vitro method for detecting intestinal barrier failure in animals |
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| CN101297880A (en) * | 2007-04-30 | 2008-11-05 | 常州高新技术产业开发区三维工业技术研究所有限公司 | Active extract containing phlorizin and uses thereof |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101297880A (en) * | 2007-04-30 | 2008-11-05 | 常州高新技术产业开发区三维工业技术研究所有限公司 | Active extract containing phlorizin and uses thereof |
Non-Patent Citations (1)
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| 赵旭涛: "《实用中医诊疗学》", 28 February 2006, 吉林科学出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111819444A (en) * | 2018-03-02 | 2020-10-23 | 赢创运营有限公司 | In vitro method for detecting intestinal barrier failure in animals |
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Application publication date: 20160323 |