CN104623368A - Decoction medicine for treating chronic glomerulonephritis and preparation method thereof - Google Patents

Abstract

The invention provides a decoction medicine for treating chronic glomerulonephritis and a preparation method thereof. The medicine is prepared from the following components in parts by weight: 1-3 parts of codonopsis pilosula, 1-3 parts of cassia twig, 1-3 parts of astragalus membranaceus, 1-3 parts of licorice root, 1-3 parts of angelica sinensis, 1-3 parts of raw Chinese yam, 1-3 parts of eucommia ulmoides, 1-3 parts of pericarpium citri reticulatae, 1-3 parts of poria cocos, 1-3 parts of corn stigma and 1-3 parts of fructus rosae laevigatae. The preparation method comprises the following steps: selecting high-quality clean first-grade codonopsis pilosula, cassia twig, astragalus membranaceus, licorice root, angelica sinensis, raw Chinese yam, eucommia ulmoides, pericarpium citri reticulatae, poria cocos, corn stigma and fructus rosae laevigatae according to the mass ratio, respectively picking out impurities and dust for later use; putting the medicinal materials into a cloth bag, binding the opening, soaking in clean water for about 30 minutes until the medicinal material tissues are permeated, and putting the soaked medicinal materials into a decoction machine, injecting cold boiled water which is 45mm over the medicinal materials to decoct for 30 minutes for the first time, filtering the decoction, injecting slightly warm boiled water to decoct for the second time for 25 minutes, combining and concentrating to obtain 1620ml of 50% decoction, filling bags and sealing.

Description

A kind of decoction medicine for the treatment of chronic glomerulonephritis and preparation method thereof

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of decoction medicine for the treatment of chronic glomerulonephritis, particularly for the field of the decoction medicine and preparation method thereof of human chronic's Patients with Glomerulonephritis.

Background technology

Chronic glomerulonephritis is called for short chronic nephritis, mean that albuminuria, hematuria, hypertension and edema are basic clinical, mode of onset is had nothing in common with each other, protracted inflammation; pathological changes is slowly in progress; can have renal hypofunction in various degree, has renal function exacerbation tendency and the one group of glomerulopathy developing into chronic renal failure the most at last.Due to histological type and the stadium difference of this group disease, main clinical manifestation can be different, and disease indicia is in variation.

So, just how finding a kind of medicine effectively can treating above-mentioned chronic glomerulonephritis, is our current problem in urgent need to solve.

Summary of the invention

The object of this invention is to provide a kind of decoction medicine for the treatment of chronic glomerulonephritis and preparation method thereof, to solve chronic glomerulonephritis patients restorative problem early.This medicine is that have advantages of perfect compatibility, the efficacy of a drug is powerful with common Chinese herbal medicine for raw material, and hit pathogenesis, has fully demonstrated tonifying speen and tonifying kidney and diuretic turbid Therapeutic Principle.

For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of decoction medicine for the treatment of chronic glomerulonephritis and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Codonopsis 1-3 part;

Ramulus Cinnamomi 1-3 part;

Radix Astragali 1-3 part;

Radix Glycyrrhizae 1-3 part;

Radix Angelicae Sinensis 1-3 part;

Rhizoma Dioscoreae 1-3 part;

Cortex Eucommiae 1-3 part;

Pericarpium Citri Reticulatae 1-3 part;

Poria 1-3 part;

Stigma Maydis 1-3 part;

Fructus Rosae Laevigatae 1-3 part.

According to the decoction medicine for the treatment of chronic glomerulonephritis provided by the present invention, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Codonopsis 1 part;

Ramulus Cinnamomi 1 part;

Radix Astragali 1 part;

1 part, Radix Glycyrrhizae;

Radix Angelicae Sinensis 1 part;

Rhizoma Dioscoreae 1 part;

The Cortex Eucommiae 1 part;

Pericarpium Citri Reticulatae 1 part;

1 part, Poria;

Stigma Maydis 1 part;

Fructus Rosae Laevigatae 1 part.

A kind of decoction medicine for the treatment of chronic glomerulonephritis and preparation method thereof, is characterized in that, described method comprises the steps:

A, the one-level Radix Codonopsis 1 part selecting high-quality clean, Ramulus Cinnamomi 1 part, Radix Astragali 1 part, 1 part, Radix Glycyrrhizae, Radix Angelicae Sinensis 1 part, Rhizoma Dioscoreae 1 part, the Cortex Eucommiae 1 part, Pericarpium Citri Reticulatae 1 part, 1 part, Poria, Stigma Maydis 1 part, Fructus Rosae Laevigatae 1 part, for subsequent use after picking decontamination and dust respectively;

B, said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.

A kind of decoction medicine for the treatment of chronic glomerulonephritis and preparation method thereof, is characterized in that, described instructions of taking is: divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32-38 agent, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.

Herb liquid provided by the present invention is oral traditional Chinese medicine composition, and it for raw material, gives full play to the property of medicine of each component with common Chinese herbal medicine:

Radix Codonopsis, nature and flavor: property is flat, sweet in the mouth, micro-acid, there is effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, the disease such as to quench one's thirst for deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat;

Ramulus Cinnamomi, nature and flavor: nature and flavor: pungent, sweet, warm in nature, have effect of expelling cold and relieving exterior syndrome, promoting the flow of QI-blood by warming the meridian, short yang transforming qi, for exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea, mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria;

Radix Astragali, nature and flavor: sweet in the mouth, tepor, have effect of invigorating QI to consolidate the body surface resistance, holder skin ulcer granulation promoting, diuretic, for diseases such as deficient qi and blood, spontaneous perspiration, chronic diarrhea proctoptosis, uterine prolapse, nephritis edema, albuminuria, diabetes, chronic ulcers;

Radix Glycyrrhizae, nature and flavor: sweet, flat, there is effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for lack of appetite, weakness of the spleen and stomach, stomachache loose stool, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity and strong;

Radix Angelicae Sinensis, nature and flavor: warm in nature, sweet in the mouth is pungent, having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation, for blood deficiency, shallow complexion, dizzy cardiopalmus, blood deficiency or have the pain cards such as the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, coronary heart diseases and angina pectoris, rheumatic arthralgia, traumatic injury concurrently;

Rhizoma Dioscoreae, nature and flavor: property is flat, sweet in the mouth, have spleen reinforcing nourishing the stomach, effect of the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission, breath with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat quench one's thirst for insufficiency of the spleen lack of appetite, chronic diarrhea not less than, the deficiency of the lung;

The Cortex Eucommiae, nature and flavor: sweet, warm, have invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect, blood leaking in gestation, frequent fetal movement unable for lumbago due to renal deficiency, muscles and bones, hypertension;

Pericarpium Citri Reticulatae, nature and flavor: acrid in the mouth, hardship, warm in nature, there is regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, effect of diuretic relieving constipation, for incoordination between the spleen and stomach, abdominal distention, anorexia, vomiting hiccup, accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm full vexed, the vertigo, edema, dysuria, constipation, acute mastitis scabies, middle fish Eriocheir sinensis poison, alcoholism etc.;

Poria, nature and flavor: sweet in the mouth, light, property are put down, and have effect of promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, have loose bowels for edema, oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, loose stool, peaceful uneasy, the palpitation with fear insomnia of the heart;

Stigma Maydis, nature and flavor: sweet, flat, nontoxic, have diuresis, expel the heat-evil, effect of suppressing the hyperactive liver, function of gallbladder promoting, for oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis;

Fructus Rosae Laevigatae, nature and flavor: sour, sweet, puckery, flat, there is effect of controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents, for emission and spermatorrhea, the enuresis, frequent micturition, bleeding not during menses, chronic diarrhea chronic dysentery.

During use, divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32-38 agent, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.This medicine is that have advantages of perfect compatibility, the efficacy of a drug is powerful with common Chinese herbal medicine for raw material, and hit pathogenesis, has fully demonstrated tonifying speen and tonifying kidney and diuretic turbid Therapeutic Principle.

Detailed description of the invention

Below embodiments of the present invention are described in detail

Chronic glomerulonephritis is called for short chronic nephritis, mean that albuminuria, hematuria, hypertension and edema are basic clinical, mode of onset is had nothing in common with each other, protracted inflammation; pathological changes is slowly in progress; can have renal hypofunction in various degree, has renal function exacerbation tendency and the one group of glomerulopathy developing into chronic renal failure the most at last.Due to histological type and the stadium difference of this group disease, main clinical manifestation can be different, and disease indicia is in variation.

The present invention is exactly treatment for above-mentioned chronic glomerulonephritis and a kind of Chinese herbal medicine formula proposed, and adopts herb liquid prepared by this formula, good drug efficacy, instant effect, has no side effect, effectively can treat chronic glomerulonephritis.Below specific embodiment provided by the present invention is described in detail.

Embodiment 1:

The one-level Radix Codonopsis 10 grams selecting high-quality clean, Ramulus Cinnamomi 3 grams, Radix Astragali 10 grams, 6 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 6 grams, Rhizoma Dioscoreae 12 grams, the Cortex Eucommiae 10 grams, Pericarpium Citri Reticulatae 6 grams, 10 grams, Poria, Stigma Maydis 30 grams, Fructus Rosae Laevigatae 15 grams, for subsequent use after picking decontamination and dust respectively; Said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.When taking, divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32-38 agent, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.

Embodiment 2:

The one-level Radix Codonopsis 12 grams selecting high-quality clean, Ramulus Cinnamomi 3.5 grams, Radix Astragali 12 grams, 7 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 7 grams, Rhizoma Dioscoreae 15 grams, the Cortex Eucommiae 12 grams, Pericarpium Citri Reticulatae 7 grams, 12 grams, Poria, Stigma Maydis 36 grams, Fructus Rosae Laevigatae 18 grams, for subsequent use after picking decontamination and dust respectively; Said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.When taking, divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32-34 agent, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.

Embodiment 3:

The one-level Radix Codonopsis 10 grams selecting high-quality clean, Ramulus Cinnamomi 3 grams, Radix Astragali 10 grams, 6 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 6 grams, Rhizoma Dioscoreae 12 grams, the Cortex Eucommiae 10 grams, Pericarpium Citri Reticulatae 6 grams, 10 grams, Poria, Stigma Maydis 30 grams, Fructus Rosae Laevigatae 15 grams, for subsequent use after picking decontamination and dust respectively; Said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.When taking, divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32-36 agent, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.

Embodiment 4:

The one-level Radix Codonopsis 12 grams selecting high-quality clean, Ramulus Cinnamomi 3.5 grams, Radix Astragali 12 grams, 7 grams, Radix Glycyrrhizae, Radix Angelicae Sinensis 7 grams, Rhizoma Dioscoreae 15 grams, the Cortex Eucommiae 12 grams, Pericarpium Citri Reticulatae 7 grams, 12 grams, Poria, Stigma Maydis 36 grams, Fructus Rosae Laevigatae 18 grams, for subsequent use after picking decontamination and dust respectively; Said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.When taking, divided by the herb liquid prepared and take for three days, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.Continue and take 32 doses, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.

The present invention is through the treatment to nearly 100 routine patients, and therapeutic effect is remarkable, has no side effect, and part allusion quotation shape case is as follows.

1, patient: Liao XX, man, 11 years old, address: Chengdu, Sichuan Province

Illness symptom: father Dai Shu: infant because puffiness of face and edema of lower limbs live children's hospital, is examined as acute glomerulonephritis on July 13rd, 1998, through more than the Drug therapy such as penicillin January, the state of an illness has no and is clearly better, heavy time light time after leaving hospital, prolong silk floss and do not heal, in these diagnosis and treatment of in March, 2000.Symptom: Mian Se Koushi is white, edema, and lower limb slightly refer to fall into, and the tired lazyness of body is played, lassitude, diet still can, the few color of urine amount is slightly yellow.Check: cardiopulmonary are normal, and liver spleen does not touch.Body of the tongue is light red, white and thin fur and moistening, thready pulse.Urine examination: albumen (Nian), erythrocyte (ten), leukocyte (ten), epithelial cell 0-4, hyaline cast (Nian), granular cast 0-3/ high power field.

Treatment: throw top and control it, every day potion, the morning, noon and afternoon service once, and take medicine after 13 doses, urine protein (ten), erythrocyte 0-2, epithelial cell 0-1.Following the service 36 doses, all diseases disappear entirely, have rosy cheeks, and urine examination is normal.Study is recovered from the second half year in 2000.Follow up a case by regular visits to, healthy, have no edema, after check again 4 urine, discovery all without exception.

2, patient: summer XX, female, 15 years old, address: Jintang County, Sichuan Province

Illness symptom: this female carrys out this diagnosis and treatment on July 3rd, 1997.Readme checks to town commune hospital because of the edema of the face two months ago, is after diagnosing " acute glomerulonephritis ", through not subtracting by the western medicines in treatment state of an illness.Symptom: face and edema of lower limbs, wear thick clothing fear of cold, face light yellow complexion is simple and unadorned, poor appetite, abdominal distention, low voice.Check: cardiopulmonary (), liver spleen does not touch, and abdomen is soft, and kidney district kowtows pain, and thin lingual fur is grey and moisten, weak pulse.Urine examination: albumen (Nian), erythrocyte (Nian), leukocyte (+), hyaline cast 0-2/ high power field.Be diagnosed as chronic glomerulonephritis.

Treatment: throw top and control it, every day potion, the morning, noon and afternoon service once, and add six bent 6g, Fructus Amomi Rotundus 6g, Radix Angelicae Sinensis 6g in top, and take medicine after 8 doses, urine volume also increases, and edema alleviates to some extent, and limbs turn temperature.Urine examination albumen (ten), erythrocyte (Nian), leukocyte is a little, cast ().Remove Radix Angelicae Sinensis in top, then enter 10 doses, edema disappears entirely, and abdomen is without swollen sense.Following the service 8 doses, without any discomfort, has had rosy cheeks.The rarely seen erythrocyte of urine examination (ten).It is advised to take LIUWEI DIHUANG WAN, each ball, every day twice.After taking 18 days, have urine examined all normal.Visit after half a year, do not recur again.

3, patient: neat XX, man, 7 years old, address: Sichuan Province's Deyang City

Illness symptom: father Dai Shu: infant, because of face, left lower extremity and the equal edema of right lower extremity, lives in certain children's hospital of city, through examining as acute glomerulonephritis, once with Drug therapy first quarter moons such as penicillins, left hospital because curative effect is not aobvious, heavy time light during the state of an illness after leaving hospital, prolong silk floss not heal, this just controlled afterwards.Symptom: Mian Se Koushi is white, edema, and lower limb slightly refer to fall into, and the tired lazyness of body is played, lassitude, diet still can, the few color of urine amount is slightly yellow.Check: cardiopulmonary are normal, and liver spleen does not touch.Body of the tongue is light red, white and thin fur and moistening, thready pulse.Urine examination: albumen (Nian), erythrocyte (ten), leukocyte (ten), epithelial cell 0-4, hyaline cast (Nian), granular cast 0-3/ high power field.

Treatment: throw top and control it, every day potion, the morning, noon and afternoon service once, and take medicine after 10 doses, urine protein (ten), erythrocyte 0-2, epithelial cell 0-1.Following the service 32 doses, all diseases are all removed and heal.Follow up a case by regular visits to 3 year, healthy, no abnormality seen.

Claims (3)

1. treat a decoction medicine for chronic glomerulonephritis, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Codonopsis 1-3 part;

Ramulus Cinnamomi 1-3 part;

Radix Astragali 1-3 part;

Radix Glycyrrhizae 1-3 part;

Radix Angelicae Sinensis 1-3 part;

Rhizoma Dioscoreae 1-3 part;

Cortex Eucommiae 1-3 part;

Pericarpium Citri Reticulatae 1-3 part;

Poria 1-3 part;

Stigma Maydis 1-3 part;

Fructus Rosae Laevigatae 1-3 part.

2. the decoction medicine for the treatment of chronic glomerulonephritis according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:

Radix Codonopsis 1 part;

Ramulus Cinnamomi 1 part;

Radix Astragali 1 part;

1 part, Radix Glycyrrhizae;

Radix Angelicae Sinensis 1 part;

Rhizoma Dioscoreae 1 part;

The Cortex Eucommiae 1 part;

Pericarpium Citri Reticulatae 1 part;

1 part, Poria;

Stigma Maydis 1 part;

Fructus Rosae Laevigatae 1 part.

3. decoction medicine of the treatment chronic glomerulonephritis described in a claim 1 or 2 and preparation method thereof, is characterized in that, described method comprises the steps:

A, according to mass parts than selecting the clean one-level Radix Codonopsis of high-quality, Ramulus Cinnamomi, Radix Astragali, Radix Glycyrrhizae, Radix Angelicae Sinensis, Rhizoma Dioscoreae, the Cortex Eucommiae, Pericarpium Citri Reticulatae, Poria, Stigma Maydis, Fructus Rosae Laevigatae, for subsequent use after picking decontamination and dust respectively;

B, said medicine to be loaded in cloth bag after tying, soak about 30 minutes in water purification, with osmotic drug degree of being organized as, then more soaked medicine is put into boiling machine, the cold boiled water injecting medicine 45mm carries out first time decoction 30 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 25 minutes, merge the herb liquid 1620 milliliters being condensed into 50%, packedly to seal.