CN105407968B - 用于对缺血性中风的超声处置的设备 - Google Patents

用于对缺血性中风的超声处置的设备 Download PDF

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Publication number
CN105407968B
CN105407968B CN201480038085.0A CN201480038085A CN105407968B CN 105407968 B CN105407968 B CN 105407968B CN 201480038085 A CN201480038085 A CN 201480038085A CN 105407968 B CN105407968 B CN 105407968B
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CN
China
Prior art keywords
ultrasound
site
apoplexy
disposal system
transducer
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Active
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CN201480038085.0A
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English (en)
Chinese (zh)
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CN105407968A (zh
Inventor
J·E·鲍尔斯
R·塞普
W·T·史
F·特兰夸尔特
Y·博伦
E·J-M·高德
E·比赫尔
F·严
M·阿迪蒂
J-M·P·R·许韦林
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Bracco Suisse SA
Koninklijke Philips NV
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Bracco Suisse SA
Koninklijke Philips Electronics NV
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Clinical applications
    • A61B8/0833Clinical applications involving detecting or locating foreign bodies or organic structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005Effects, e.g. on tissue
    • A61B2017/22007Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005Effects, e.g. on tissue
    • A61B2017/22007Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/483Diagnostic techniques involving the acquisition of a 3D volume of data
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5246Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from the same or different imaging techniques, e.g. color Doppler and B-mode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0039Ultrasound therapy using microbubbles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0052Ultrasound therapy using the same transducer for therapy and imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0078Ultrasound therapy with multiple treatment transducers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0086Beam steering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Surgical Instruments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Percussion Or Vibration Massage (AREA)
CN201480038085.0A 2013-07-03 2014-07-02 用于对缺血性中风的超声处置的设备 Active CN105407968B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361842402P 2013-07-03 2013-07-03
US201361842404P 2013-07-03 2013-07-03
US61/842,402 2013-07-03
US61/842,404 2013-07-03
EP13182062.3 2013-08-28
EP13182062 2013-08-28
PCT/EP2014/064052 WO2015000953A1 (en) 2013-07-03 2014-07-02 Devices and methods for the ultrasound treatment of ischemic stroke

Publications (2)

Publication Number Publication Date
CN105407968A CN105407968A (zh) 2016-03-16
CN105407968B true CN105407968B (zh) 2019-09-03

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CN201480038085.0A Active CN105407968B (zh) 2013-07-03 2014-07-02 用于对缺血性中风的超声处置的设备

Country Status (7)

Country Link
US (1) US10926112B2 (https=)
EP (1) EP3016713B1 (https=)
JP (1) JP6568057B2 (https=)
CN (1) CN105407968B (https=)
BR (1) BR112015032732B1 (https=)
CA (1) CA2917095C (https=)
WO (1) WO2015000953A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101500650B (zh) * 2006-08-11 2012-08-08 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统
EP2903688A4 (en) 2012-10-05 2016-06-15 Univ Michigan BLADE-INDUCED COLOR DOPPLER FEEDBACK DURING A HISTOTRIPSIA
WO2015003154A1 (en) 2013-07-03 2015-01-08 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
BR112015032926B1 (pt) 2013-07-03 2022-04-05 Histosonics, Inc. Sistema de terapia de ultrassom
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
US11141179B2 (en) 2014-12-11 2021-10-12 Koninklijke Philips N.V. Setting of sonothromobolysis ultrasound output power
WO2016210133A1 (en) * 2015-06-24 2016-12-29 The Regents Of The Universtiy Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
JP7534839B2 (ja) * 2015-12-09 2024-08-15 コーニンクレッカ フィリップス エヌ ヴェ 超音波血栓溶解用及び血管音響共振器を介した他の治療用のインターリーブビームパターン
US10589129B2 (en) * 2016-09-14 2020-03-17 Insightec, Ltd. Therapeutic ultrasound with reduced interference from microbubbles
EP3554382B1 (en) 2016-12-16 2021-03-10 Koninklijke Philips N.V. Adaptive pulsing for sonothrombolysis treatment
US11369810B2 (en) * 2016-12-19 2022-06-28 Michalakis Averkiou Method and apparatus for ultrasonic mediation of drug delivery using microbubbles
WO2020039082A1 (en) * 2018-08-24 2020-02-27 Neuravi Limited Apparatus for managing acute ischemic events
EP4477245A3 (en) 2018-08-24 2025-02-19 Neuravi Limited Apparatus for managing acute ischemic events
JP2022510654A (ja) 2018-11-28 2022-01-27 ヒストソニックス,インコーポレーテッド 組織破砕システムおよび方法
EP3669802A1 (en) * 2018-12-19 2020-06-24 Neuravi Limited Apparatus for managing acute ischemic events
CA3169465A1 (en) 2020-01-28 2021-08-05 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
BR112022025722A2 (pt) 2020-06-18 2023-03-07 Histosonics Inc Sistemas e métodos de acoplamento acústico e paciente de histotripsia
US12551222B2 (en) 2020-08-11 2026-02-17 Quantanosis Ai, Inc. Operator-independent histotripsy device
CA3190517A1 (en) 2020-08-27 2022-03-03 Timothy Lewis HALL Ultrasound transducer with transmit-receive capability for histotripsy
EP3970653B8 (en) * 2020-09-21 2024-01-10 Servicio Andaluz De Salud Device for non-invasive preventive cleaning of cerebrospinal fluid shunt systems
IL308943A (en) 2021-06-07 2024-01-01 Univ Michigan Regents All-inclusive ultrasound systems and methods that include histotripsy
WO2022260746A1 (en) 2021-06-07 2022-12-15 The Regents Of The University Of Michigan Minimally invasive histotripsy systems and methods
CN113974765B (zh) * 2021-10-22 2022-09-06 北京荷清和创医疗科技有限公司 介入式除栓装置及促溶栓模块
CN115105123A (zh) * 2022-05-31 2022-09-27 深圳迈瑞生物医疗电子股份有限公司 一种超声成像系统和方法
EP4608504A1 (en) 2022-10-28 2025-09-03 Histosonics, Inc. Histotripsy systems and methods
USD1037522S1 (en) 2022-11-30 2024-07-30 Eaton Intelligent Power Limited Floodlight
KR20260003742A (ko) 2023-04-20 2026-01-07 히스토소닉스, 인크. 치료 계획 및 요법을 위한 사용자 인터페이스들 및 작업 흐름들을 포함하는 히스토트립시 시스템들 및 연관된 방법들

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1792334A (zh) * 2005-10-31 2006-06-28 西安交通大学 基于包膜微泡的灌注成像与超声控制释放的系统和方法
CN101500651A (zh) * 2006-08-11 2009-08-05 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (https=) 1990-04-02 1993-05-01 Sint Sa
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US6333021B1 (en) 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
US5558092A (en) 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US6013032A (en) 1998-03-13 2000-01-11 Hewlett-Packard Company Beamforming methods and apparatus for three-dimensional ultrasound imaging using two-dimensional transducer array
US5997479A (en) 1998-05-28 1999-12-07 Hewlett-Packard Company Phased array acoustic systems with intra-group processors
US6530885B1 (en) 2000-03-17 2003-03-11 Atl Ultrasound, Inc. Spatially compounded three dimensional ultrasonic images
US6468216B1 (en) 2000-08-24 2002-10-22 Kininklijke Philips Electronics N.V. Ultrasonic diagnostic imaging of the coronary arteries
US6723050B2 (en) 2001-12-19 2004-04-20 Koninklijke Philips Electronics N.V. Volume rendered three dimensional ultrasonic images with polar coordinates
JP4139916B2 (ja) 2002-07-03 2008-08-27 株式会社東京大学Tlo 超音波照射方法及び超音波照射装置
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
US8038616B2 (en) * 2003-05-30 2011-10-18 Surf Technology As Acoustic imaging by nonlinear low frequency manipulation of high frequency scattering and propagation properties
US20050019744A1 (en) 2003-07-25 2005-01-27 La Jolla Bioengineering Institute Ultrasound-assisted ischemic reperfusion
CN100466986C (zh) 2004-02-05 2009-03-11 皇家飞利浦电子股份有限公司 使用谐波造影剂的灌注和血流超声成像
US20120046547A1 (en) * 2004-10-06 2012-02-23 Guided Therapy Systems, Llc System and method for cosmetic treatment
WO2007058668A1 (en) * 2005-11-18 2007-05-24 Imarx Therapeutics, Inc. Ultrasound apparatus and method to treat an ischemic stroke
CN101500650B (zh) 2006-08-11 2012-08-08 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统
US20080097206A1 (en) 2006-09-27 2008-04-24 Chomas James E Enhanced contrast agent augmented ultrasound thrombus treatment
US8425424B2 (en) * 2008-11-19 2013-04-23 Inightee Ltd. Closed-loop clot lysis
US9011819B2 (en) * 2009-09-22 2015-04-21 Targeson, Inc. Optical imaging contrast agents and uses thereof
US20120296241A1 (en) * 2011-05-22 2012-11-22 Mishelevich David J Ultrasound neuromodulation for treatment of autism spectrum disorder and alzheimers disease and other dementias
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
JP5541946B2 (ja) * 2010-02-26 2014-07-09 オリンパス株式会社 超音波治療装置
US20110251489A1 (en) 2010-04-07 2011-10-13 Physiosonics, Inc. Ultrasound monitoring systems, methods and components
WO2012042423A1 (en) 2010-09-30 2012-04-05 Koninklijke Philips Electronics N.V. Monitoring and control of microbubble cavitation in therapeutic ultrasound
US8603014B2 (en) 2010-10-05 2013-12-10 Cerevast Therapeutics, Inc. Hands-free operator-independent transcranial ultrasound apparatus and methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1792334A (zh) * 2005-10-31 2006-06-28 西安交通大学 基于包膜微泡的灌注成像与超声控制释放的系统和方法
CN101500651A (zh) * 2006-08-11 2009-08-05 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统

Also Published As

Publication number Publication date
CA2917095C (en) 2021-11-02
BR112015032732B1 (pt) 2022-05-17
BR112015032732A2 (pt) 2017-07-25
EP3016713B1 (en) 2023-03-01
US20160279449A1 (en) 2016-09-29
JP6568057B2 (ja) 2019-08-28
CN105407968A (zh) 2016-03-16
US10926112B2 (en) 2021-02-23
WO2015000953A1 (en) 2015-01-08
JP2016526976A (ja) 2016-09-08
CA2917095A1 (en) 2015-01-08
EP3016713A1 (en) 2016-05-11

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