CN105407968B - 用于对缺血性中风的超声处置的设备 - Google Patents

用于对缺血性中风的超声处置的设备 Download PDF

Info

Publication number
CN105407968B
CN105407968B CN201480038085.0A CN201480038085A CN105407968B CN 105407968 B CN105407968 B CN 105407968B CN 201480038085 A CN201480038085 A CN 201480038085A CN 105407968 B CN105407968 B CN 105407968B
Authority
CN
China
Prior art keywords
ultrasound
site
apoplexy
disposal system
transducer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480038085.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN105407968A (zh
Inventor
J·E·鲍尔斯
R·塞普
W·T·史
F·特兰夸尔特
Y·博伦
E·J-M·高德
E·比赫尔
F·严
M·阿迪蒂
J-M·P·R·许韦林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco Suisse SA
Koninklijke Philips NV
Original Assignee
Bracco Suisse SA
Koninklijke Philips NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Suisse SA, Koninklijke Philips NV filed Critical Bracco Suisse SA
Publication of CN105407968A publication Critical patent/CN105407968A/zh
Application granted granted Critical
Publication of CN105407968B publication Critical patent/CN105407968B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0833—Clinical applications involving detecting or locating foreign bodies or organic structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B2017/22005—Effects, e.g. on tissue
    • A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
    • A61B2017/22008—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing used or promoted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5246—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from the same or different imaging techniques, e.g. color Doppler and B-mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0039—Ultrasound therapy using microbubbles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0086—Beam steering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Surgical Instruments (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Percussion Or Vibration Massage (AREA)
CN201480038085.0A 2013-07-03 2014-07-02 用于对缺血性中风的超声处置的设备 Active CN105407968B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361842402P 2013-07-03 2013-07-03
US201361842404P 2013-07-03 2013-07-03
US61/842,404 2013-07-03
US61/842,402 2013-07-03
EP13182062 2013-08-28
EP13182062.3 2013-08-28
PCT/EP2014/064052 WO2015000953A1 (en) 2013-07-03 2014-07-02 Devices and methods for the ultrasound treatment of ischemic stroke

Publications (2)

Publication Number Publication Date
CN105407968A CN105407968A (zh) 2016-03-16
CN105407968B true CN105407968B (zh) 2019-09-03

Family

ID=49036479

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480038085.0A Active CN105407968B (zh) 2013-07-03 2014-07-02 用于对缺血性中风的超声处置的设备

Country Status (7)

Country Link
US (1) US10926112B2 (cg-RX-API-DMAC10.html)
EP (1) EP3016713B1 (cg-RX-API-DMAC10.html)
JP (1) JP6568057B2 (cg-RX-API-DMAC10.html)
CN (1) CN105407968B (cg-RX-API-DMAC10.html)
BR (1) BR112015032732B1 (cg-RX-API-DMAC10.html)
CA (1) CA2917095C (cg-RX-API-DMAC10.html)
WO (1) WO2015000953A1 (cg-RX-API-DMAC10.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101500650B (zh) * 2006-08-11 2012-08-08 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统
EP2903688A4 (en) 2012-10-05 2016-06-15 Univ Michigan BLADE-INDUCED COLOR DOPPLER FEEDBACK DURING A HISTOTRIPSIA
JP6600304B2 (ja) 2013-07-03 2019-10-30 ヒストソニックス，インコーポレーテッド 衝撃散乱を使用した気泡雲形成のために最適化されたヒストトリプシ励起シーケンス
WO2015003154A1 (en) 2013-07-03 2015-01-08 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
CN107106870B (zh) 2014-12-11 2020-06-05 皇家飞利浦有限公司 超声溶栓超声输出功率的设置
WO2016210133A1 (en) * 2015-06-24 2016-12-29 The Regents Of The Universtiy Of Michigan Histotripsy therapy systems and methods for the treatment of brain tissue
JP7534839B2 (ja) * 2015-12-09 2024-08-15 コーニンクレッカ フィリップス エヌ ヴェ 超音波血栓溶解用及び血管音響共振器を介した他の治療用のインターリーブビームパターン
US10589129B2 (en) * 2016-09-14 2020-03-17 Insightec, Ltd. Therapeutic ultrasound with reduced interference from microbubbles
EP3554382B1 (en) 2016-12-16 2021-03-10 Koninklijke Philips N.V. Adaptive pulsing for sonothrombolysis treatment
US11369810B2 (en) * 2016-12-19 2022-06-28 Michalakis Averkiou Method and apparatus for ultrasonic mediation of drug delivery using microbubbles
ES3009676T3 (en) 2018-08-24 2025-03-31 Neuravi Ltd Apparatus for managing acute ischemic events
WO2020039082A1 (en) * 2018-08-24 2020-02-27 Neuravi Limited Apparatus for managing acute ischemic events
US11813484B2 (en) 2018-11-28 2023-11-14 Histosonics, Inc. Histotripsy systems and methods
JP2020099688A (ja) * 2018-12-19 2020-07-02 ニューラヴィ・リミテッド 急性虚血性イベントを管理するための方法及び装置
US11813485B2 (en) 2020-01-28 2023-11-14 The Regents Of The University Of Michigan Systems and methods for histotripsy immunosensitization
CN116113376A (zh) 2020-06-18 2023-05-12 希斯托索尼克斯公司 组织摧毁声学和患者耦合系统和方法
EP4196023A4 (en) * 2020-08-11 2024-09-25 Hassan, Ameer E. OPERATOR-INDEPENDENT HISTOTRIPSY DEVICE
CA3190517A1 (en) 2020-08-27 2022-03-03 Timothy Lewis HALL Ultrasound transducer with transmit-receive capability for histotripsy
EP3970653B8 (en) * 2020-09-21 2024-01-10 Servicio Andaluz De Salud Device for non-invasive preventive cleaning of cerebrospinal fluid shunt systems
WO2022260746A1 (en) 2021-06-07 2022-12-15 The Regents Of The University Of Michigan Minimally invasive histotripsy systems and methods
WO2022260747A1 (en) 2021-06-07 2022-12-15 The Regents Of The University Of Michigan All-in-one ultrasound systems and methods including histotripsy
CN113974765B (zh) * 2021-10-22 2022-09-06 北京荷清和创医疗科技有限公司 介入式除栓装置及促溶栓模块
CN115105123A (zh) * 2022-05-31 2022-09-27 深圳迈瑞生物医疗电子股份有限公司 一种超声成像系统和方法
US20240149078A1 (en) 2022-10-28 2024-05-09 Histosonics, Inc. Histotripsy systems and methods
WO2024097771A2 (en) 2022-11-01 2024-05-10 Histosonics, Inc. Histotripsy systems and methods
USD1037522S1 (en) 2022-11-30 2024-07-30 Eaton Intelligent Power Limited Floodlight
JP2026516719A (ja) 2023-04-20 2026-05-26 ヒストソニックス，インコーポレーテッド 治療計画および治療のためのユーザインターフェースとワークフローとを含むヒストトリプシーシステムおよび関連方法
WO2025090672A1 (en) 2023-10-23 2025-05-01 Histosonics, Inc. Histotripsy systems and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1792334A (zh) * 2005-10-31 2006-06-28 西安交通大学 基于包膜微泡的灌注成像与超声控制释放的系统和方法
CN101500651A (zh) * 2006-08-11 2009-08-05 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (cg-RX-API-DMAC10.html) 1990-04-02 1993-05-01 Sint Sa
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US6333021B1 (en) 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
US5558092A (en) 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US6013032A (en) 1998-03-13 2000-01-11 Hewlett-Packard Company Beamforming methods and apparatus for three-dimensional ultrasound imaging using two-dimensional transducer array
US5997479A (en) 1998-05-28 1999-12-07 Hewlett-Packard Company Phased array acoustic systems with intra-group processors
US6530885B1 (en) 2000-03-17 2003-03-11 Atl Ultrasound, Inc. Spatially compounded three dimensional ultrasonic images
US6468216B1 (en) 2000-08-24 2002-10-22 Kininklijke Philips Electronics N.V. Ultrasonic diagnostic imaging of the coronary arteries
US6723050B2 (en) 2001-12-19 2004-04-20 Koninklijke Philips Electronics N.V. Volume rendered three dimensional ultrasonic images with polar coordinates
JP4139916B2 (ja) * 2002-07-03 2008-08-27 株式会社東京大学Ｔｌｏ 超音波照射方法及び超音波照射装置
EP1590006B1 (en) 2003-02-04 2010-09-08 Bracco Suisse SA Ultrasound contrast agents and process for the preparation thereof
US8038616B2 (en) * 2003-05-30 2011-10-18 Surf Technology As Acoustic imaging by nonlinear low frequency manipulation of high frequency scattering and propagation properties
US20050019744A1 (en) * 2003-07-25 2005-01-27 La Jolla Bioengineering Institute Ultrasound-assisted ischemic reperfusion
US20080234580A1 (en) 2004-02-05 2008-09-25 Koninklijke Philips Electronics, N.V. Ultrasonic Imaging of Perfusion and Blood Flow with Harmonic Contrast Agents
US20120016239A1 (en) * 2004-10-06 2012-01-19 Guided Therapy Systems, Llc Systems for cosmetic treatment
US20080262350A1 (en) * 2005-11-18 2008-10-23 Imarx Therapeutics, Inc. Ultrasound Apparatus and Method to Treat an Ischemic Stroke
CN101500650B (zh) 2006-08-11 2012-08-08 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统
US20080097206A1 (en) 2006-09-27 2008-04-24 Chomas James E Enhanced contrast agent augmented ultrasound thrombus treatment
US8425424B2 (en) * 2008-11-19 2013-04-23 Inightee Ltd. Closed-loop clot lysis
EP2480127A4 (en) * 2009-09-22 2015-06-24 Targeson Inc Contrast agents for optical imaging and uses thereof
US20120296241A1 (en) * 2011-05-22 2012-11-22 Mishelevich David J Ultrasound neuromodulation for treatment of autism spectrum disorder and alzheimers disease and other dementias
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
JP5541946B2 (ja) * 2010-02-26 2014-07-09 オリンパス株式会社 超音波治療装置
US20110251489A1 (en) 2010-04-07 2011-10-13 Physiosonics, Inc. Ultrasound monitoring systems, methods and components
WO2012042423A1 (en) 2010-09-30 2012-04-05 Koninklijke Philips Electronics N.V. Monitoring and control of microbubble cavitation in therapeutic ultrasound
US8603014B2 (en) 2010-10-05 2013-12-10 Cerevast Therapeutics, Inc. Hands-free operator-independent transcranial ultrasound apparatus and methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1792334A (zh) * 2005-10-31 2006-06-28 西安交通大学 基于包膜微泡的灌注成像与超声控制释放的系统和方法
CN101500651A (zh) * 2006-08-11 2009-08-05 皇家飞利浦电子股份有限公司 用于颅脑血流成像和微泡加强血块溶解的超声系统

Also Published As

Publication number Publication date
BR112015032732A2 (pt) 2017-07-25
EP3016713B1 (en) 2023-03-01
US20160279449A1 (en) 2016-09-29
EP3016713A1 (en) 2016-05-11
BR112015032732B1 (pt) 2022-05-17
WO2015000953A1 (en) 2015-01-08
JP2016526976A (ja) 2016-09-08
CA2917095C (en) 2021-11-02
CA2917095A1 (en) 2015-01-08
US10926112B2 (en) 2021-02-23
JP6568057B2 (ja) 2019-08-28
CN105407968A (zh) 2016-03-16

Similar Documents

Publication Publication Date Title
EP3016713B1 (en) Devices for the ultrasound treatment of ischemic stroke
US12303152B2 (en) Histotripsy for thrombolysis
EP3210540B1 (en) Ultrasound-mediated inducement, detection, and enhancement of stable cavitation
EP1711109B1 (en) Localized production of microbubbles and control of cavitational and heating effects by use of enhanced ultrasound
CN101252970B (zh) 具有治疗换能器放大器的组合成像和治疗换能器
JP2009508649A (ja) パルス・キャビテーション超音波療法
JP7534839B2 (ja) 超音波血栓溶解用及び血管音響共振器を介した他の治療用のインターリーブビームパターン
WO2009094554A2 (en) Histotripsy for thrombolysis
US20080319316A1 (en) Combination Imaging and Therapy Transducer
JP5851127B2 (ja) 超音波照射装置及び超音波照射装置の作動方法
Ashida et al. Transluminal approach with bubble-seeded histotripsy for cancer treatment with ultrasonic mechanical effects
Raiton et al. Non-invasive cavitation nuclei trap for Histotripsy

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant