CN105407896B - 缓释的地塞米松在白内障手术后的炎症中的应用 - Google Patents

缓释的地塞米松在白内障手术后的炎症中的应用 Download PDF

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Publication number
CN105407896B
CN105407896B CN201480041856.1A CN201480041856A CN105407896B CN 105407896 B CN105407896 B CN 105407896B CN 201480041856 A CN201480041856 A CN 201480041856A CN 105407896 B CN105407896 B CN 105407896B
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Prior art keywords
dexamethasone
dosage form
single unit
unit dosage
days
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English (en)
Chinese (zh)
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CN105407896A (zh
Inventor
弗农·G·王
威廉·S·怀特
美·W·胡
格伦·T·黄
法伊纳·卡拉桑娜
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Icon Bioscience Inc
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Icon Bioscience Inc
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Priority to CN201910639315.3A priority Critical patent/CN110339153A/zh
Publication of CN105407896A publication Critical patent/CN105407896A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201480041856.1A 2013-05-24 2014-05-23 缓释的地塞米松在白内障手术后的炎症中的应用 Active CN105407896B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910639315.3A CN110339153A (zh) 2013-05-24 2014-05-23 地塞米松单位剂型、试剂盒及白内障手术后炎症中的应用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361827091P 2013-05-24 2013-05-24
US61/827,091 2013-05-24
PCT/US2014/039319 WO2014190248A1 (en) 2013-05-24 2014-05-23 Use of sustained release dexamethasone in post-cataract surgery inflammation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910639315.3A Division CN110339153A (zh) 2013-05-24 2014-05-23 地塞米松单位剂型、试剂盒及白内障手术后炎症中的应用

Publications (2)

Publication Number Publication Date
CN105407896A CN105407896A (zh) 2016-03-16
CN105407896B true CN105407896B (zh) 2019-08-27

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480041856.1A Active CN105407896B (zh) 2013-05-24 2014-05-23 缓释的地塞米松在白内障手术后的炎症中的应用
CN201910639315.3A Pending CN110339153A (zh) 2013-05-24 2014-05-23 地塞米松单位剂型、试剂盒及白内障手术后炎症中的应用

Family Applications After (1)

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CN201910639315.3A Pending CN110339153A (zh) 2013-05-24 2014-05-23 地塞米松单位剂型、试剂盒及白内障手术后炎症中的应用

Country Status (9)

Country Link
US (4) US10028965B2 (enExample)
EP (2) EP3003318B1 (enExample)
JP (1) JP6530744B2 (enExample)
KR (1) KR102245354B1 (enExample)
CN (2) CN105407896B (enExample)
AU (1) AU2014268434B2 (enExample)
CA (1) CA2913336C (enExample)
ES (1) ES2902951T3 (enExample)
WO (1) WO2014190248A1 (enExample)

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LT2701773T (lt) 2011-04-25 2019-07-10 Icon Bioscience, Inc. Injekcinio švirkšto dozės kreiptuvai
EP3302382A4 (en) 2015-05-29 2019-02-20 Allergan, Inc. IMPLANT FOR THE TREATMENT OF OCULAR DISEASE
US10682340B2 (en) 2016-06-30 2020-06-16 Durect Corporation Depot formulations
BR112018077259A2 (pt) 2016-06-30 2019-06-18 Durect Corporation formulações depot
JP2020059652A (ja) * 2016-12-26 2020-04-16 参天製薬株式会社 タフルプロストとクエン酸エステルとを含有するデポ剤
IL276048B2 (en) 2018-02-09 2024-11-01 Icon Bioscience Inc Systems, kits and methods for loading and delivering a small volume dose from a syringe
WO2020168106A1 (en) 2019-02-13 2020-08-20 Notable Labs, Inc. Combinations of agonists of protein kinase c with steroids or retinoic acids for the treatment of cancer
IT201900003529A1 (it) * 2019-03-11 2020-09-11 Ntc S R L Riduzione della posologia antibiotica in composizioni antibiotico/antinfiammatorio in associazione tra loro per uso oftalmico
US11911499B2 (en) 2019-11-07 2024-02-27 Resurge Therapeutics, Inc. System and method for prostate treatment
US11957654B2 (en) 2022-01-29 2024-04-16 Resurge Therapeutics, Inc. Treating benign prostatic hyperplasia
US11974979B2 (en) 2022-01-29 2024-05-07 Resurge Therapeutics, Inc. Treatments for benign prostatic hyperplasia

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DE3500103C2 (de) 1985-01-04 1987-01-22 R.P. Scherer GmbH, 6930 Eberbach Pharmazeutische Zubereitung mit einem in Wasser und Verdauungssäften schwer löslichen Wirkstoff
US4889845A (en) 1986-06-09 1989-12-26 American Cyanamid Company Vehicle for topical application of pharmaceuticals
AU5178193A (en) 1992-11-09 1994-06-08 Quest International B.V. Solubilizing agents
US5747058A (en) 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
US20040024006A1 (en) 1996-05-06 2004-02-05 Simon David Lew Opioid pharmaceutical compositions
US20030216303A1 (en) 1998-03-06 2003-11-20 Michael Ambuhl Emulsion preconcentrates containing cyclosporin or a macrolide
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US6726918B1 (en) * 2000-07-05 2004-04-27 Oculex Pharmaceuticals, Inc. Methods for treating inflammation-mediated conditions of the eye
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US20040253293A1 (en) * 2003-06-16 2004-12-16 Afshin Shafiee Rate controlled release of a pharmaceutical agent in a biodegradable device
ITMI20032087A1 (it) 2003-10-27 2005-04-28 Pharmafilm S R L Film autosupportanti per uso farmaceutico ed alimentare.
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Also Published As

Publication number Publication date
CA2913336C (en) 2020-12-15
EP3003318B1 (en) 2021-12-22
KR20160040471A (ko) 2016-04-14
WO2014190248A1 (en) 2014-11-27
EP3003318A4 (en) 2017-01-04
CA2913336A1 (en) 2014-11-27
US10028965B2 (en) 2018-07-24
US20230078906A1 (en) 2023-03-16
ES2902951T3 (es) 2022-03-30
US20190105330A1 (en) 2019-04-11
US10159683B2 (en) 2018-12-25
JP6530744B2 (ja) 2019-06-12
US20180303851A1 (en) 2018-10-25
CN105407896A (zh) 2016-03-16
AU2014268434A1 (en) 2015-12-10
EP3003318A1 (en) 2016-04-13
CN110339153A (zh) 2019-10-18
US20160120879A1 (en) 2016-05-05
JP2016526039A (ja) 2016-09-01
EP4082525A1 (en) 2022-11-02
AU2014268434B2 (en) 2018-11-22
KR102245354B1 (ko) 2021-04-30

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Application publication date: 20160316

Assignee: Okonvision biomedical (Shanghai) Co.,Ltd.

Assignor: Ou Kangweishishengwu

Contract record no.: X2020990000546

Denomination of invention: Application of sustained release dexamethasone in inflammation after cataract surgery

Granted publication date: 20190827

License type: Exclusive License

Record date: 20201019