CN105377289A - 用于下调Bcl-xL和/或Bcl-w的活性和/或量的试剂 - Google Patents

用于下调Bcl-xL和/或Bcl-w的活性和/或量的试剂 Download PDF

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Publication number
CN105377289A
CN105377289A CN201480035042.7A CN201480035042A CN105377289A CN 105377289 A CN105377289 A CN 105377289A CN 201480035042 A CN201480035042 A CN 201480035042A CN 105377289 A CN105377289 A CN 105377289A
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bcl
reagent
disease
activity
amount
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Chinese (zh)
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V.克里扎诺夫斯基
N.皮佩
R.约塞夫
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Yeda Research and Development Co Ltd
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Yeda Research and Development Co Ltd
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CN201480035042.7A 2013-04-21 2014-04-13 用于下调Bcl-xL和/或Bcl-w的活性和/或量的试剂 Pending CN105377289A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361814286P 2013-04-21 2013-04-21
US61/814286 2013-04-21
PCT/IL2014/050358 WO2014174511A1 (en) 2013-04-21 2014-04-13 Agents for downregulation of the activity and/or amount of bcl-xl and/or bcl-w

Publications (1)

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CN105377289A true CN105377289A (zh) 2016-03-02

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US (1) US20160122758A1 (enExample)
EP (1) EP2988767A1 (enExample)
JP (1) JP2016516808A (enExample)
CN (1) CN105377289A (enExample)
BR (1) BR112015026702A2 (enExample)
CA (1) CA2909380A1 (enExample)
MX (1) MX2015014582A (enExample)
RU (1) RU2015149680A (enExample)
WO (1) WO2014174511A1 (enExample)

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CN109387493A (zh) * 2018-09-21 2019-02-26 山东大学 一种pH响应型自辅因子DNAzyme ZnO纳米探针及其制备方法与应用
CN112294962A (zh) * 2020-11-13 2021-02-02 上海长海医院 Bcl-2及bcl-xl抑制剂在瘢痕治疗中的应用
CN113038956A (zh) * 2018-12-05 2021-06-25 日东电工株式会社 癌处置用RNAi分子
WO2022027953A1 (zh) * 2020-08-03 2022-02-10 天津医科大学 C188-9、Venetoclax、Bumetanide在纤维化疾病药物中的应用
WO2023024664A1 (zh) * 2021-08-26 2023-03-02 山东第一医科大学附属眼科研究所(山东省眼科研究所、山东第一医科大学附属青岛眼科医院) Abt-263在制备抑制角膜移植免疫排斥反应的药物中的应用

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US9901080B2 (en) 2012-08-23 2018-02-27 Buck Institute For Research On Aging Transgenic mouse having a transgene that converts a prodrug into a cytotoxic compound in senescent cells
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KR102447884B1 (ko) 2016-04-21 2022-09-27 바이오벤처스, 엘엘씨 항-세포자멸적 bcl-2 계열 단백질의 열화를 유도하는 화합물 및 이의 용도
KR102011105B1 (ko) * 2017-02-22 2019-08-14 국립암센터 고시폴 및 펜포르민을 유효성분으로 포함하는 췌장암 예방 및 치료용 약학적 조성물
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CN117866015A (zh) 2018-04-30 2024-04-12 联合生物科技公司 一种临床管理中使用的化合物及其用途
CA3056878C (en) 2018-04-30 2021-03-30 Unity Biotechnology Phospholidines that are bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
US12084423B2 (en) 2018-05-18 2024-09-10 Bioventures, Llc Piperlongumine analogues and uses thereof
US10717722B2 (en) 2018-06-13 2020-07-21 Unity Biotechnology, Inc. Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
IL275186A (en) 2020-06-07 2022-01-01 Yeda Res & Dev Human antibodies against grp94 and uses
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WO2023064937A1 (en) * 2021-10-14 2023-04-20 Arizona Board Of Regents On Behalf Of Arizona State University Programmable delivery platforms for rna structures
WO2023096448A1 (ko) * 2021-11-29 2023-06-01 에스케이케미칼 주식회사 오바토클락스 대사성 질환 및 섬유화 질환 치료 용도

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