CN105367465A - 一种医药中间体羰基取代芳基硫醚化合物的合成方法 - Google Patents
一种医药中间体羰基取代芳基硫醚化合物的合成方法 Download PDFInfo
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- CN105367465A CN105367465A CN201510646571.7A CN201510646571A CN105367465A CN 105367465 A CN105367465 A CN 105367465A CN 201510646571 A CN201510646571 A CN 201510646571A CN 105367465 A CN105367465 A CN 105367465A
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- 0 C*C(C(C(O)=O)N)=* Chemical compound C*C(C(C(O)=O)N)=* 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
- B01J31/24—Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
- B01J31/2404—Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B45/00—Formation or introduction of functional groups containing sulfur
- C07B45/06—Formation or introduction of functional groups containing sulfur of mercapto or sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2231/00—Catalytic reactions performed with catalysts classified in B01J31/00
- B01J2231/40—Substitution reactions at carbon centres, e.g. C-C or C-X, i.e. carbon-hetero atom, cross-coupling, C-H activation or ring-opening reactions
- B01J2231/42—Catalytic cross-coupling, i.e. connection of previously not connected C-atoms or C- and X-atoms without rearrangement
- B01J2231/4277—C-X Cross-coupling, e.g. nucleophilic aromatic amination, alkoxylation or analogues
- B01J2231/4294—C-X Cross-coupling, e.g. nucleophilic aromatic amination, alkoxylation or analogues using S nucleophiles, e.g. thiols
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
- B01J2531/0213—Complexes without C-metal linkages
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/02—Compositional aspects of complexes used, e.g. polynuclearity
- B01J2531/0238—Complexes comprising multidentate ligands, i.e. more than 2 ionic or coordinative bonds from the central metal to the ligand, the latter having at least two donor atoms, e.g. N, O, S, P
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/10—Complexes comprising metals of Group I (IA or IB) as the central metal
- B01J2531/16—Copper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2531/00—Additional information regarding catalytic systems classified in B01J31/00
- B01J2531/80—Complexes comprising metals of Group VIII as the central metal
- B01J2531/84—Metals of the iron group
- B01J2531/847—Nickel
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Description
Claims (10)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710215227.1A CN107098837A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215205.5A CN107098835A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201510646571.7A CN105367465B (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215208.9A CN107011222A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215221.4A CN106986799A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215209.3A CN106928107A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215228.6A CN106977435A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215215.9A CN107011223A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215212.5A CN107098836A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510646571.7A CN105367465B (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
Related Child Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710215215.9A Division CN107011223A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215227.1A Division CN107098837A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215208.9A Division CN107011222A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215221.4A Division CN106986799A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215209.3A Division CN106928107A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215212.5A Division CN107098836A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215228.6A Division CN106977435A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215205.5A Division CN107098835A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105367465A true CN105367465A (zh) | 2016-03-02 |
CN105367465B CN105367465B (zh) | 2017-04-12 |
Family
ID=55370158
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710215227.1A Withdrawn CN107098837A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215212.5A Withdrawn CN107098836A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215209.3A Withdrawn CN106928107A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215215.9A Withdrawn CN107011223A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215208.9A Withdrawn CN107011222A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215205.5A Withdrawn CN107098835A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215228.6A Withdrawn CN106977435A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215221.4A Withdrawn CN106986799A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201510646571.7A Expired - Fee Related CN105367465B (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
Family Applications Before (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710215227.1A Withdrawn CN107098837A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215212.5A Withdrawn CN107098836A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215209.3A Withdrawn CN106928107A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215215.9A Withdrawn CN107011223A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体硫醚化合物的合成方法 |
CN201710215208.9A Withdrawn CN107011222A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215205.5A Withdrawn CN107098835A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体硫醚化合物的合成方法 |
CN201710215228.6A Withdrawn CN106977435A (zh) | 2015-10-08 | 2015-10-08 | 一种医药中间体羰基取代芳基硫醚化合物的合成方法 |
CN201710215221.4A Withdrawn CN106986799A (zh) | 2015-10-08 | 2015-10-08 | 医药中间体羰基取代芳基硫醚化合物的合成方法 |
Country Status (1)
Country | Link |
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CN (9) | CN107098837A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108409617A (zh) * | 2018-03-10 | 2018-08-17 | 湘潭大学 | 一种硫醚化合物的合成方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110256400B (zh) * | 2019-07-05 | 2021-08-24 | 南京林业大学 | 一种亚砜参与芳基化合成多取代环1,2-二酮的制备方法 |
Citations (4)
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JPH10237058A (ja) * | 1997-02-24 | 1998-09-08 | Sumitomo Chem Co Ltd | 2,2’− ビス(5− オキソテトラヒドロフラン−2− カルボニルアミノ)−5,5’− ジニトロジフェニルジスルフィド及びその製造方法 |
WO2002002522A1 (en) * | 2000-06-29 | 2002-01-10 | Abbott Laboratories | Aryl phenycyclopropyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents |
CN103922978A (zh) * | 2014-05-07 | 2014-07-16 | 江南大学 | 一种简单、绿色制备新型材料芳香族硫醚的方法 |
CN104744325A (zh) * | 2013-12-30 | 2015-07-01 | 中国人民大学 | 一种α-羟基硫醚及其制备方法与应用 |
-
2015
- 2015-10-08 CN CN201710215227.1A patent/CN107098837A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215212.5A patent/CN107098836A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215209.3A patent/CN106928107A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215215.9A patent/CN107011223A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215208.9A patent/CN107011222A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215205.5A patent/CN107098835A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215228.6A patent/CN106977435A/zh not_active Withdrawn
- 2015-10-08 CN CN201710215221.4A patent/CN106986799A/zh not_active Withdrawn
- 2015-10-08 CN CN201510646571.7A patent/CN105367465B/zh not_active Expired - Fee Related
Patent Citations (4)
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JPH10237058A (ja) * | 1997-02-24 | 1998-09-08 | Sumitomo Chem Co Ltd | 2,2’− ビス(5− オキソテトラヒドロフラン−2− カルボニルアミノ)−5,5’− ジニトロジフェニルジスルフィド及びその製造方法 |
WO2002002522A1 (en) * | 2000-06-29 | 2002-01-10 | Abbott Laboratories | Aryl phenycyclopropyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents |
CN104744325A (zh) * | 2013-12-30 | 2015-07-01 | 中国人民大学 | 一种α-羟基硫醚及其制备方法与应用 |
CN103922978A (zh) * | 2014-05-07 | 2014-07-16 | 江南大学 | 一种简单、绿色制备新型材料芳香族硫醚的方法 |
Non-Patent Citations (5)
Title |
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HAO CAO 等: "Iodine-catalyzed C–H/S–H oxidative coupling:from 1,3-diketones and thiophenols to bdicarbonyl thioethers", 《RSC ADVANCES》 * |
JIWEN YUAN 等: "I2-catalyzed oxidative C(sp3)–H/S–H coupling:utilizing alkanes and mercaptans as the nucleophiles", 《CHEM. COMMUN.》 * |
MUHAMMAD A. RASHID 等: "Synthesis of functionalized diaryl sulfides based on regioselective one-pot cyclizations of 1,3-bis(trimethylsilyloxy)-1,3-butadienes", 《TETRAHEDRON》 * |
PEI GUAN 等: "Efficient nickel/N-heterocyclic carbene catalyzed C-S cross-coupling", 《TETRAHEDRON LETTERS》 * |
秦元成 等: "铜催化C—S 偶联反应的研究新进展", 《有机化学》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108409617A (zh) * | 2018-03-10 | 2018-08-17 | 湘潭大学 | 一种硫醚化合物的合成方法 |
CN108409617B (zh) * | 2018-03-10 | 2019-09-27 | 湘潭大学 | 一种硫醚化合物的合成方法 |
Also Published As
Publication number | Publication date |
---|---|
CN105367465B (zh) | 2017-04-12 |
CN107098837A (zh) | 2017-08-29 |
CN106977435A (zh) | 2017-07-25 |
CN106928107A (zh) | 2017-07-07 |
CN107098836A (zh) | 2017-08-29 |
CN107098835A (zh) | 2017-08-29 |
CN107011223A (zh) | 2017-08-04 |
CN107011222A (zh) | 2017-08-04 |
CN106986799A (zh) | 2017-07-28 |
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Effective date of registration: 20170227 Address after: Shandong province Qingdao Jianmin street 266200 Jimo City No. 4 people's Hospital of Jimo City Applicant after: Zhang Daojing Address before: Room 61, No. 2, South Village, Xuhui District, Shanghai, 200237, China Applicant before: Zhang Yan |
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