CN105801338B - 一种应用乙酰丙酮钯合成医药中间体菲类化合物的方法 - Google Patents
一种应用乙酰丙酮钯合成医药中间体菲类化合物的方法 Download PDFInfo
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- CN105801338B CN105801338B CN201610216414.7A CN201610216414A CN105801338B CN 105801338 B CN105801338 B CN 105801338B CN 201610216414 A CN201610216414 A CN 201610216414A CN 105801338 B CN105801338 B CN 105801338B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
- C07B37/10—Cyclisation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/272—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions
- C07C17/275—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by addition reactions of hydrocarbons and halogenated hydrocarbons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2/00—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms
- C07C2/02—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by addition between unsaturated hydrocarbons
- C07C2/42—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by addition between unsaturated hydrocarbons homo- or co-oligomerisation with ring formation, not being a Diels-Alder conversion
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/20—Polycyclic condensed hydrocarbons
- C07C15/27—Polycyclic condensed hydrocarbons containing three rings
- C07C15/30—Phenanthrenes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
- C07C25/18—Polycyclic aromatic halogenated hydrocarbons
- C07C25/22—Polycyclic aromatic halogenated hydrocarbons with condensed rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/127—Preparation from compounds containing pyridine rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
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Claims (6)
Priority Applications (1)
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CN201610216414.7A CN105801338B (zh) | 2015-03-06 | 2015-03-06 | 一种应用乙酰丙酮钯合成医药中间体菲类化合物的方法 |
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CN201610216414.7A CN105801338B (zh) | 2015-03-06 | 2015-03-06 | 一种应用乙酰丙酮钯合成医药中间体菲类化合物的方法 |
CN201510100568.5A CN104692986B (zh) | 2015-03-06 | 2015-03-06 | 一种医药中间体菲类化合物的合成方法 |
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CN201510100568.5A Division CN104692986B (zh) | 2015-03-06 | 2015-03-06 | 一种医药中间体菲类化合物的合成方法 |
Publications (2)
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CN105801338A CN105801338A (zh) | 2016-07-27 |
CN105801338B true CN105801338B (zh) | 2018-08-14 |
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CN201510100568.5A Active CN104692986B (zh) | 2015-03-06 | 2015-03-06 | 一种医药中间体菲类化合物的合成方法 |
CN201610216414.7A Active CN105801338B (zh) | 2015-03-06 | 2015-03-06 | 一种应用乙酰丙酮钯合成医药中间体菲类化合物的方法 |
CN201610216366.1A Withdrawn CN105801336A (zh) | 2015-03-06 | 2015-03-06 | 一种应用三氟乙酸钯合成医药中间体菲化合物的方法 |
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CN (3) | CN104692986B (zh) |
WO (22) | WO2016141829A1 (zh) |
Families Citing this family (3)
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US9996386B2 (en) | 2014-07-23 | 2018-06-12 | Intel Corporation | Mid-thread pre-emption with software assisted context switch |
CN104692986B (zh) * | 2015-03-06 | 2016-05-25 | 谭永山 | 一种医药中间体菲类化合物的合成方法 |
CN105153152B (zh) * | 2015-08-28 | 2017-06-13 | 泉州奔众空气过滤网有限公司 | 一种咪唑类稠环化合物的合成方法 |
Citations (1)
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CN102827077A (zh) * | 2012-09-07 | 2012-12-19 | 浙江大学 | 一种菲啶衍生物的制备方法 |
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CN104692986B (zh) * | 2015-03-06 | 2016-05-25 | 谭永山 | 一种医药中间体菲类化合物的合成方法 |
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2015
- 2015-03-06 CN CN201510100568.5A patent/CN104692986B/zh active Active
- 2015-03-06 CN CN201610216414.7A patent/CN105801338B/zh active Active
- 2015-03-06 CN CN201610216366.1A patent/CN105801336A/zh not_active Withdrawn
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2016
- 2016-03-03 WO PCT/CN2016/075414 patent/WO2016141829A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075413 patent/WO2016141828A1/zh active Application Filing
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- 2016-03-03 WO PCT/CN2016/075454 patent/WO2016141844A1/zh active Application Filing
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- 2016-03-03 WO PCT/CN2016/075401 patent/WO2016141824A1/zh active Application Filing
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- 2016-03-03 WO PCT/CN2016/075404 patent/WO2016141827A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075402 patent/WO2016141825A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075436 patent/WO2016141836A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075453 patent/WO2016141843A1/zh active Application Filing
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- 2016-03-03 WO PCT/CN2016/075437 patent/WO2016141837A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075435 patent/WO2016141835A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075416 patent/WO2016141831A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075403 patent/WO2016141826A1/zh active Application Filing
- 2016-03-03 WO PCT/CN2016/075418 patent/WO2016141833A1/zh active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102827077A (zh) * | 2012-09-07 | 2012-12-19 | 浙江大学 | 一种菲啶衍生物的制备方法 |
Non-Patent Citations (3)
Title |
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2,3-Dichloro-5,6-dicyano-para-benzoquinone(DDQ)/Methanesulfonic Acid(MsOH)-Mediated Intramolecular Arene-Alkene Oxidative Coupling;Ko Hoon Kim, et al.;《Advanced Synthesis & Catalysis》;20140220;第356卷(第4期);第697-704页 * |
Ligand-Free Heck Reaction: Pd(OAc)2 as an Active Catalyst Revisited;Qingwei Yao et al.;《The Journal of Organic Chemistry》;20030816;第68卷(第19期);第7528-7531页 * |
Palladium-catalyzed double cross-coupling reaction of 1,2-bis(pinacolatoboryl)alkenes and -arenes with 2,2′-dibromobiaryls: annulative approach to functionalized polycyclic aromatic hydrocarbons;Masaki Shimizu, et al.;《Tetrahedron》;20110812;第67卷(第41期);第8014-8026页 * |
Also Published As
Publication number | Publication date |
---|---|
WO2016141832A1 (zh) | 2016-09-15 |
WO2016141828A1 (zh) | 2016-09-15 |
WO2016141830A1 (zh) | 2016-09-15 |
WO2016141833A1 (zh) | 2016-09-15 |
WO2016141842A1 (zh) | 2016-09-15 |
WO2016141829A1 (zh) | 2016-09-15 |
WO2016141824A1 (zh) | 2016-09-15 |
CN105801336A (zh) | 2016-07-27 |
CN104692986B (zh) | 2016-05-25 |
WO2016141838A1 (zh) | 2016-09-15 |
WO2016141823A1 (zh) | 2016-09-15 |
WO2016141826A1 (zh) | 2016-09-15 |
WO2016141827A1 (zh) | 2016-09-15 |
WO2016141836A1 (zh) | 2016-09-15 |
WO2016141839A1 (zh) | 2016-09-15 |
WO2016141835A1 (zh) | 2016-09-15 |
WO2016141834A1 (zh) | 2016-09-15 |
WO2016141843A1 (zh) | 2016-09-15 |
WO2016141840A1 (zh) | 2016-09-15 |
CN105801338A (zh) | 2016-07-27 |
CN104692986A (zh) | 2015-06-10 |
WO2016141831A1 (zh) | 2016-09-15 |
WO2016141841A1 (zh) | 2016-09-15 |
WO2016141844A1 (zh) | 2016-09-15 |
WO2016141825A1 (zh) | 2016-09-15 |
WO2016141837A1 (zh) | 2016-09-15 |
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Effective date of registration: 20191111 Address after: Room 1602, B1 Floor, Lijinxiu Jiangnan (West District), east of Gouyun Road, north of Yinhe No. 2 Road, Suzhou City, Anhui Province Patentee after: Suzhou Huiteng Intellectual Property Consulting Co., Ltd. Address before: 810000, Xining, Qinghai Province West Victory Road Park Lane No. 1 waterfront Star District No. two building Patentee before: Hu Shuting |
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Effective date of registration: 20211103 Address after: 467400 Bai Yi Tang Cun, Shangjiu Town, Baofeng County, Pingdingshan City, Henan Province (50m south of Boxiang carbon) Patentee after: Baofeng tongxinde technology R & D Co.,Ltd. Address before: Room 1602, B1 / F, Jinxiu Jiangnan (West District), east of Qingyun Road, north of Yinhe 2nd Road, Suzhou City, Anhui Province Patentee before: Suzhou Teng Teng Intellectual Property Advisory Co.,Ltd. |