CN105362953A - 一种治疗颈椎病的药物及其制备方法 - Google Patents
一种治疗颈椎病的药物及其制备方法 Download PDFInfo
- Publication number
- CN105362953A CN105362953A CN201510941892.XA CN201510941892A CN105362953A CN 105362953 A CN105362953 A CN 105362953A CN 201510941892 A CN201510941892 A CN 201510941892A CN 105362953 A CN105362953 A CN 105362953A
- Authority
- CN
- China
- Prior art keywords
- radix
- grams
- gram
- rhizoma
- dries
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/264—Aristolochia (Dutchman's pipe)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Gastroenterology & Hepatology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗颈椎病的药物及其制备方法,其主要是由白芍、威灵仙、淫羊藿、龟甲、骨碎补、紫河车、葛根、乌梢蛇、路路通、地龙、牛膝、杜仲、鹿衔草、秦艽、钩藤、寻骨风、鸡血藤、当归、伸筋草、全蝎、天南星、天麻、僵蚕、茯神、川芎、羌活按一定重量配比制备而成。本发明药物具有祛风活络,和血舒筋,补虚益肾,祛风除湿,温经通脉的功能,用于治疗颈椎病见效快、疗效好,不复发。
Description
技术领域
本发明涉及一种治疗颈椎病的药物及其制备方法,属中药领域。
背景技术
颈椎病是颈椎骨关节炎、增生性颈椎炎、颈神经根综合征、颈椎间盘脱出症的总称,是一种以退行性病理改变为基础的疾患。中医则认为颈椎病与气血不足,外感风寒,脉络气血运行不畅,肝肾不足有关。由于西药治疗副作用大,因此人们对有效治疗颈椎病的中药药物存在极大的需求,至今为止,还没有发现关于本发明的有关报道。
发明内容
本发明人依据中医理论的研究和临床试验的反复验证,终于找到了有效治疗颈椎病的药物,从而完成了本发明。
本发明的目的就是提供一种有效治疗颈椎病的中药组合药物。
本发明的另一目的就是提供了该中药组合药物的制备方法。
本发明药物是选择白芍、威灵仙、淫羊藿、龟甲、骨碎补、紫河车、葛根、乌梢蛇、血风藤、路路通、地龙、牛膝、杜仲、鹿衔草、秦艽、钩藤、寻骨风、鸡血藤、当归、伸筋草、全蝎、天南星、天麻、僵蚕、茯神、川芎、羌活、姜黄、巴戟天、桂枝、石决明药物进行组合制备的,将这些药物组合使得各药物功效产生协同作用,从而能够有效治疗颈椎病。其中,选用白芍是因为其性味苦酸,凉,入肝、脾经,有养血柔肝,缓中止痛,敛阴收汗的功能,治胸腹胁肋疼痛,泻痢腹痛,自汗盗汗,阴虚发热,月经不调,崩漏,带下。选用威灵仙是因为其性味辛咸,温,有毒,入膀胱经,有祛风湿,通经络,消痰涎,散癖积的功能,治痛风、顽痹、腰膝冷痛,脚气,疟疾,癥瘕积聚,破伤风,扁桃体炎,诸骨鲠咽。选用淫羊藿是因为其性味辛甘,温,入肝、肾经,有补肾壮阳,祛风除湿的功能,治阳痿不举,小便淋沥,筋骨挛急,半身不遂,腰膝无力,风湿痹痛,四脚不仁。选用龟甲是因为其性味咸,平,入肝、脾经,有养阴清热,平肝熄风,软坚散结的功能,治劳热骨蒸,阴虚风动,劳疟疟母,癥瘕痃癖,经闭经漏,小儿惊癎。选用骨碎补是因为其性味苦,温,入肝、肾经,有补肾,活血,止血的功能,治肾虚久泻及腰痛,风湿痹痛,齿痛,耳鸣,跌打闪挫、骨伤,阑尾炎,斑秃,鸡眼。选用紫河车是因为其性味甘咸,温,入肺、肝、肾经,有补气,养血,益精的功能,治虚损,羸瘦,劳热骨蒸,咳喘,咯血,盗汗,遗精,阳痿,妇女血气不足,不孕或乳少。选用葛根是因为其性味甘辛,平,入脾、胃经,有升阳解肌,透疹止泻,除烦止渴的功能,治伤寒,温热,头痛,项强,烦热消喝,泄泻,痢疾,癍诊不透,高血压,心绞痛,耳聋。选用乌梢蛇是因为其性味甘,平,归肝经,有祛风活络,镇痉,治风湿痹痛,四肢麻木,抽搐痉挛,皮肤瘙痒,麻风。选用血风藤是因为其性味甘温,有补益气血、祛风活络的功能,治气血亏损,风湿疼痛,跌打损伤。选用路路通是因为其性味苦平,通行十二经,有祛风通络,利尿除湿的功能,治水肿,胀满,经闭,乳少,手足拘挛。选用地龙是因为其性味咸,寒,入肝、脾、肺经,有清热,平肝,止喘,通络的功能,治高热狂躁,惊风抽搐,风热头痛,目赤,中风半身不遂,喘息,喉痹,关节疼痛,齿衄,小便不通,瘰疬,痄腮,疮疡。选用牛膝是因为其性味甘苦酸,平,入肝、肾经,生用散瘀血,消痈肿,治淋病,尿血,经闭,癥瘕,难产,胞衣不下,产后瘀血腹痛,喉痹,痈肿,跌打损伤,熟用补肝肾,强筋骨,治腰膝骨痛,四肥拘挛,痿痹。选用杜仲是因为其性味甘微辛,温,入肝、肾经,有补肝肾,强筋骨,安胎的功能,治腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,高血压。选用鹿衔草是因为其性味甘苦,温,入肝、肾二经,有补虚,益肾,祛风除湿,活血调经的功能,治虚弱咳嗽,劳伤吐血,风湿关节痛,崩漏,白带,外伤出血。选用秦艽是因为其性味苦辛,平,入肝、胃、胆经,有祛风除湿,和血舒筋,清热利尿的功能,治风湿痹痛,筋骨拘挛,黄疸,便血,骨蒸潮热,小儿疳热,小便不利。选用钩藤是因为其性味苦,凉,入肝、心经,有清热平肝,熄风定惊的功能,治小儿惊癎瘈瘲,大人血压偏高,头晕、目眩,妇人子癎。选用寻骨风是因其性味辛,苦,平,归肝,胃经,祛风除湿,活血通络;止痛。主风湿痹痛;肢体麻木;筋骨拘挛;脘腹疼痛;跌打伤痛;外伤出血;乳痈及多种化脓性感染、腹痛,疟疾。选用鸡血藤是因为其性味苦甘,温,入心、脾二经,有活血、舒筋的功能,治腰膝酸痛,麻木瘫痪,月经不调。选用当归是因为其性味甘辛,温,入心、肝、脾经,有补血和血,调经止痛,润燥滑肠的功能,治月经不调,经闭腹痛,癥瘕结聚,崩漏,血虚头痛,眩晕,痿痹,肠燥难便,赤痢后重,痈疽疮疡,金疮,跌扑损伤。用伸筋草是因为其性味苦辛,温,入肝、胃、肾三经,有祛风散寒,除湿消肿,舒筋活血的功能,治风寒湿痹,关节酸痛,皮肤麻木,四肢软弱,水肿,跌打损伤。选用全蝎是因为其性味咸辛,平,有毒,有祛风,止痉,通络,解毒的功能,治惊风抽搐,癫癎,中风,半身不遂,口眼斜,偏头痛,风湿痹痛,破伤风,淋巴结结核,风疹疮肿。选用天南星是因为其性味苦辛,温,有毒,入肺、肝、脾经,有燥湿化痰,祛风定惊,消肿散结的功能,治中风痰瘰,口眼喎斜,半身不遂,癫癎,惊风,破伤风,风痰眩晕,喉痹,瘰疬,痈肿,跌扑损伤,蛇虫咬伤。选用天麻是因为其性味甘,平,入肝经,有息风,定惊的功能,治眩晕眼黑,头风头痛,肢体麻木,半身不遂,语言蹇涩,小儿惊癎动风。选用僵蚕是因为其性味辛、咸,平,归肝,肺经。祛风解痉,化痰散结。用于中风口眼歪斜,惊痫抽搐,头赐,喉痹,瘰疠结核,风疹丹毒。选用茯神是因为其性味甘淡,平,入心、脾经,有宁心,安神,利水的功能,治心虚惊悸,健忘,失眠,惊癎,小便不利。选用川芎是因为其性味辛,温,入肝、胆经,有行气开郁,祛风燥湿,活血止痛的功能,治风冷头痛旋晕,胁痛腹疼,寒痹筋挛,经闭,难产,产后瘀阻块痛,痈疽疮疡。选用羌活是因为其性味辛苦,温,入膀胱、肾经,有散表寒,祛风湿,利关节的功能,治感冒风寒,头痛无汗,风寒湿痹,项强筋急,骨节酸疼,风水浮肿,痈疽疮毒。选用姜黄是因为其性味辛苦,温,入脾、肝经,有破血,行气,通经,止痛的功能,治心腹痞满胀痛,臂痛,癥瘕,妇女血瘀经闭,产后瘀停腹痛,跌扑损伤,痈肿。选用巴戟天是因为其性味辛甘,温,入肝、肾经,有补肾阳,壮筋骨,祛风湿的功能,治阳痿,少腹冷痛,小便不禁,子宫虚冷,风寒湿痹,腰膝酸痛。选用桂枝是因为其性味辛甘,温,入膀胱、心、肺经,有发汗解肌,温经通脉的功能,治风寒表证,肩背肢节酸疼,胸痹痰饮,经闭癥瘕。选用石决明是因为其性味咸,平,入肝、肾经,有平肝潜阳,除热,明目的功能,治风阳上扰、头痛眩晕,惊搐,骨蒸劳热,青盲内障。
具体实施方式
本发明组分的药物用量也是发明人经过大量摸索总结得出的,各组分的用量在下述重量范围内都具有较好的疗效:
白芍10-20克,威灵仙10-15克,淫羊藿10-20克,龟甲10-15克,骨碎补15-25克,紫河车10-20克,葛根10-20克,乌梢蛇10-15克,血风藤10-20克,路路通8-15克,地龙7-12克,牛膝10-15克,杜仲10-15克,鹿衔草15-25克,秦艽10-15克,钩藤10-15克,寻骨风10-20克,鸡血藤15-25克,当归10-20克,伸筋草10-20克,全蝎4-8克,天南星4-8克,天麻10-20克,僵蚕5-15克,茯神7-12克,川芎5-15克,羌活5-15克,姜黄5-15克,巴戟天10-20克,桂枝7-12克,石决明10-15克。
优选为:
白芍15克,威灵仙12克,淫羊藿15克,龟甲12克,骨碎补20克,紫河车15克,葛根15克,乌梢蛇12克,血风藤15克,路路通12克,地龙9克,牛膝12克,杜仲12克,鹿衔草20克,秦艽12克,钩藤12克,寻骨风15克,鸡血藤20克,当归15克,伸筋草15克,全蝎5克,天南星5克,天麻15克,僵蚕10克,茯神9克,川芎10克,羌活10克,姜黄10克,巴戟天15克,桂枝9克,石决明12克。
本发明药物的制备方法如下
一、备料
1、白芍:拣去杂质,分开大小个,用水浸泡至八成透,捞出,晒晾,润至内外湿度均匀,切片,干燥;
2、威灵仙:拣净杂质,除去残茎,用水浸泡,捞出润透,切段,晒干;
3、淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
4、龟甲:用水浸泡,去净皮肉,洗净,晒干;
5、骨碎补:去净泥砂杂质,洗净,稍浸泡,润透,切片,晒干;
6、紫河车:用新鲜的紫河车,横直割开血管,用水反复洗漂干净;
7、葛根:拣去杂质,洗净,用水浸泡,捞出,润透,及时切片,晒干;
8、乌梢蛇:取原药材,刷去灰屑,用时去头、鳞,切段;
9、血风藤:拣净杂质,洗净切片,晒干;
10、路路通:除去杂质,洗净,晒干;
11、地龙:拣去杂质,用水漂净,及时捞出,晒干,切段;
12、牛膝:拣去杂质,洗净,润软,去芦,切段,晒干;
13、杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
14、鹿衔草:拣去杂质,筛去泥沙,洗净,稍润,切细,晒干;
15、秦艽:拣去杂质,除去芦头,稍浸,润透切片,晒干;
16、钩藤:拣去老梗、杂质,洗净,晒干;
17、寻骨风:夏秋季采收,晒干,切段,生用;
18、鸡血藤:用水润透,切片,或蒸软后乘热切片,晒干;
19、当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
20、伸筋草:筛去灰屑,拣净杂质,切成小段;
21、全蝎:清水漂去盐质,晒干,或微火焙用;
22、天南星:拣去杂质,洗净灰屑,晒干;
23、天麻:拣去杂质,大小分档,用水浸泡至七成透,捞出,稍晾,再润至内外温度均匀,切片,晒干;
24、僵蚕:取原药材,除去残丝,杂质;
25、茯神:取原药材,除去杂质,洗净,润透,切成正方形的厚生或块,阴干;
26川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
27、羌活:拣去杂质,洗净,润透,切片,晾干;
28、姜黄:拣去杂质,用水浸泡,捞起,润透后切片,晒干;
29、巴戟天:拣去杂质,用热水泡透后,趁热抽去木心,切段,晒干;
30、桂枝:用水稍浸泡,捞出,闷润至透,切片,晾干,筛去屑;
31、石决明:洗净晾干,敲成碎块。
二、制备
1、将炮制后的白芍、威灵仙、淫羊藿、龟甲、骨碎补、紫河车、葛根、乌梢蛇、血风藤、路路通、地龙、牛膝、杜仲、鹿衔草、秦艽、钩藤、寻骨风、鸡血藤、当归、伸筋草、全蝎、天南星、天麻、僵蚕、茯神、川芎、羌活、姜黄、巴戟天、桂枝、石决明放入煎药容器内,第一次加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内。
2、将过滤的药渣加6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液。、
3、将两次煎煮液混合搅拌均匀,分为4剂服用。
组方中乌梢蛇有祛风活络,镇痉,治风湿痹痛,四肢麻木,抽搐痉挛的功能为君药;鹿衔草补虚,益肾,祛风除湿,活血;羌活有散表寒,祛风湿,利关节的功能,二者为臣药,三味药共同发挥祛风除湿,舒筋活血,通经活络的作用,治疗颈椎病效力全面,且以祛风活络,舒筋活血为主可治本,桂枝有发汗解肌,温经通脉的功能为佐药,秦艽有祛风除湿,和血舒筋的功能为使药,与余下诸药是治标。
本发明药物具有祛风活络,和血舒筋,补虚益肾,祛风除湿,温经通脉的功能,用于治疗颈椎病,疗程短、见效快、治愈后不复发。
具体实施方式:
以下通过试验例来进一步阐述本发明所述药物的有益效果,这些试验例包括本发明药物的动物毒性试验报告和临床疗效观察资料。
[试验例1]本发明药物的动物毒性试验报告:
取家兔30只,雌雄兼用,体重2.0—2.5kg,分两组,每组15只,其中一组为超剂量试验组,另一组为正常量试验组。服用药液超常量组为20ml/kg,正常量为10ml/kg,给药方式为灌胃法给药,每天两次,连服7天,每天观察给药反应,结果表明二组家兔活动、饮食正常,药物无不良毒副作用。
[试验例2]本发明药物的临床疗效观察
1、一般资料
收治颈椎病门诊患者共35例。
2、诊断标准
典型症状为颈肩部疼痛和上肢麻木感、下肢乏力、行走困难、并伴有头晕、恶心、呕吐症状。
3、治疗方法
选用上述药剂,给患者服用,每次服用1剂,每天早、晚各服1次,7天为一个疗程,连续服用3个疗程。
4、疗效评定标准
显效:颈椎病症状消失,体质恢复正常,痊愈;
好转:患者颈肩疼痛,四肢无力,头晕恶心现象减轻,颈椎病症状明显好转,体质逐步恢复;
无效:达不到好转标准者。
5、治疗结果(见下表)
在上述治疗中,用本发明药物治疗颈椎病患者35例,结果显效29例,显效率为82.85%,好转5例,好转率为14.28%,无效1例,总有效率为97.14%。
Claims (3)
1.一种治疗颈椎病的药物,其特征在于:它是由下列重量范围内的原料药制成:
白芍10-20克,威灵仙10-15克,淫羊藿10-20克,龟甲10-15克,骨碎补15-25克,紫河车10-20克,葛根10-20克,乌梢蛇10-15克,血风藤10-20克,路路通8-15克,地龙7-12克,牛膝10-15克,杜仲10-15克,鹿衔草15-25克,秦艽10-15克,钩藤10-15克,寻骨风10-20克,鸡血藤15-25克,当归10-20克,伸筋草10-20克,全蝎4-8克,天南星4-8克,天麻10-20克,僵蚕5-15克,茯神7-12克,川芎5-15克,羌活5-15克,姜黄5-15克,巴戟天10-20克,桂枝7-12克,石决明10-15克。
2.根据权利要求1所述的药物,其中各原料药的用量为:
白芍15克,威灵仙12克,淫羊藿15克,龟甲12克,骨碎补20克,紫河车15克,葛根15克,乌梢蛇12克,血风藤15克,路路通12克,地龙9克,牛膝12克,杜仲12克,鹿衔草20克,秦艽12克,钩藤12克,寻骨风15克,鸡血藤20克,当归15克,伸筋草15克,全蝎5克,天南星5克,天麻15克,僵蚕10克,茯神9克,川芎10克,羌活10克,姜黄10克,巴戟天15克,桂枝9克,石决明12克。
3.根据权利要求1或2所述药物的制备方法,它包括下列步骤:
(一)备料
(1)白芍:拣去杂质,分开大小个,用水浸泡至八成透,捞出,晒晾,润至内外湿度均匀,切片,干燥;
(2)威灵仙:拣净杂质,除去残茎,用水浸泡,捞出润透,切段,晒干;
(3)淫羊藿:拣净杂质,去梗,切丝,筛去碎屑;
(4)龟甲:用水浸泡,去净皮肉,洗净,晒干;
(5)骨碎补:去净泥砂杂质,洗净,稍浸泡,润透,切片,晒干;
(6)紫河车:用新鲜的紫河车,横直割开血管,用水反复洗漂干净;
(7)葛根:拣去杂质,洗净,用水浸泡,捞出,润透,及时切片,晒干;
(8)乌梢蛇:取原药材,刷去灰屑,用时去头、鳞,切段;
(9)血风藤:拣净杂质,洗净切片,晒干;
(10)路路通:除去杂质,洗净,晒干;
(11)地龙:拣去杂质,用水漂净,及时捞出,晒干,切段;
(12)牛膝:拣去杂质,洗净,润软,去芦,切段,晒干;
(13)杜仲:除去粗皮,洗净,润透,切成方块或丝条,晒干;
(14)鹿衔草:拣去杂质,筛去泥沙,洗净,稍润,切细,晒干;
(15)秦艽:拣去杂质,除去芦头,稍浸,润透切片,晒干;
(16)钩藤:拣去老梗、杂质,洗净,晒干;
(17)寻骨风:夏秋季采收,晒干,切段,生用;
(18)鸡血藤:用水润透,切片,或蒸软后乘热切片,晒干;
(19)当归:拣去杂质,洗净,闷润,稍晾,切片晒干;
(20)伸筋草:筛去灰屑,拣净杂质,切成小段;
(21)全蝎:清水漂去盐质,晒干,或微火焙用;
(22)天南星:拣去杂质,洗净灰屑,晒干;
(23)天麻:拣去杂质,大小分档,用水浸泡至七成透,捞出,稍晾,再润至内外温度均匀,切片,晒干;
(24)僵蚕:取原药材,除去残丝,杂质;
(25)茯神:取原药材,除去杂质,洗净,润透,切成正方形的厚生或块,阴干;
(26)川芎:拣去杂质,分开大、小个,用水浸泡,晒晾,闷润后切片,干燥;
(27)羌活:拣去杂质,洗净,润透,切片,晾干;
(28)姜黄:拣去杂质,用水浸泡,捞起,润透后切片,晒干;
(29)巴戟天:拣去杂质,用热水泡透后,趁热抽去木心,切段,晒干;
(30)桂枝:用水稍浸泡,捞出,闷润至透,切片,晾干,筛去屑;
(31)石决明:洗净晾干,敲成碎块;
(二)制备
(1)将炮制后的白芍、威灵仙、淫羊藿、龟甲、骨碎补、紫河车、葛根、乌梢蛇、血风藤、路路通、地龙、牛膝、杜仲、鹿衔草、秦艽、钩藤、寻骨风、鸡血藤、当归、伸筋草、全蝎、天南星、天麻、僵蚕、茯神、川芎、羌活、姜黄、巴戟天、桂枝、石决明放入煎药容器内,加水8倍量,浸泡100分钟后,武火煎煮沸腾,再用文火煎煮20分钟,过滤得第一次煎煮液,将第一次煎煮液倒入容器内;
(2)将过滤的药渣加水6倍量,武火煮沸,再用文火煎煮20分钟,过滤得第二次煎煮液;
(3)将两次煎煮液混合搅拌均匀即得,分为4剂服用。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510941892.XA CN105362953A (zh) | 2015-12-16 | 2015-12-16 | 一种治疗颈椎病的药物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510941892.XA CN105362953A (zh) | 2015-12-16 | 2015-12-16 | 一种治疗颈椎病的药物及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105362953A true CN105362953A (zh) | 2016-03-02 |
Family
ID=55365906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510941892.XA Pending CN105362953A (zh) | 2015-12-16 | 2015-12-16 | 一种治疗颈椎病的药物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105362953A (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101040978A (zh) * | 2007-04-19 | 2007-09-26 | 徐恒雁 | 一种内服治疗颈椎病的中药组合物 |
CN101254282A (zh) * | 2008-03-21 | 2008-09-03 | 舒财 | 一种治疗颈椎病的药物组合物 |
CN103083609A (zh) * | 2011-10-28 | 2013-05-08 | 刘亚芝 | 用于治疗颈椎病、腰椎间盘突出和强直性脊柱炎的中药 |
-
2015
- 2015-12-16 CN CN201510941892.XA patent/CN105362953A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101040978A (zh) * | 2007-04-19 | 2007-09-26 | 徐恒雁 | 一种内服治疗颈椎病的中药组合物 |
CN101254282A (zh) * | 2008-03-21 | 2008-09-03 | 舒财 | 一种治疗颈椎病的药物组合物 |
CN103083609A (zh) * | 2011-10-28 | 2013-05-08 | 刘亚芝 | 用于治疗颈椎病、腰椎间盘突出和强直性脊柱炎的中药 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103611085B (zh) | 一种治疗痛风性关节炎的药物及其制备方法 | |
CN103638386B (zh) | 一种治疗风寒湿痹的药物及其制备方法 | |
CN101642548B (zh) | 治疗腰腿疼痛的中药膏贴及其制备方法 | |
CN105535371A (zh) | 一种治疗膝关节滑膜炎的中药 | |
CN103977306A (zh) | 一种治疗乙型肝炎的药物及其制备方法 | |
CN103735934B (zh) | 一种治疗腰部疼痛的药物及其制备方法 | |
CN105381411A (zh) | 一种治疗癫痫的药物及其制备方法 | |
CN105031138A (zh) | 一种治疗腰椎间盘突出的药物及其制备方法 | |
CN105031013A (zh) | 一种治疗腰椎骨质增生的药物及其制备方法 | |
CN105012430A (zh) | 一种治疗坐骨神经病痛的药物及其制备方法 | |
CN103735920B (zh) | 一种治疗半身不遂的药物及其制备方法 | |
CN103656294B (zh) | 一种治疗小儿急性肾小球肾炎的药物及其制备方法 | |
CN105343582A (zh) | 一种治疗破伤风的药物及其制备方法 | |
CN105362953A (zh) | 一种治疗颈椎病的药物及其制备方法 | |
CN105169307A (zh) | 一种治疗类风湿性关节炎的药物及其制备方法 | |
CN105412825A (zh) | 一种治疗高脂血症的药物及其制备方法 | |
CN106177857A (zh) | 一种治疗习惯性流产的药物及其制备方法 | |
CN105213667A (zh) | 一种治疗偏瘫的药物及其制备方法 | |
CN103638466B (zh) | 一种治疗颈椎病的药物及其制备方法 | |
CN103638482B (zh) | 一种治疗慢性荨麻疹的药物及其制备方法 | |
CN103611086B (zh) | 一种治疗脂溢性皮炎的药物及其制备方法 | |
CN104056228A (zh) | 一种治疗小儿厌食症的药物及其制备方法 | |
CN102846900B (zh) | 一种治疗肩关节周围炎的药物及其制备方法 | |
CN106110185A (zh) | 一种治疗肩周炎的药物及其制备方法 | |
CN106237169A (zh) | 一种治疗白带异常的药物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160302 |