CN105362510A - 一种治疗慢性前列腺炎药物 - Google Patents

一种治疗慢性前列腺炎药物 Download PDF

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CN105362510A
CN105362510A CN201510845659.1A CN201510845659A CN105362510A CN 105362510 A CN105362510 A CN 105362510A CN 201510845659 A CN201510845659 A CN 201510845659A CN 105362510 A CN105362510 A CN 105362510A
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王菊明
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Suzhou Fengling Pharmaceutical Co Ltd
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Abstract

本发明属于中药领域，具体公开了一种治疗慢性前列腺炎的药物，由如下重量份数的原料制备得到：黄皮叶20份、绿衣枳壳22份、诃子叶25份、百部还魂24份、乳白香青20份、雪里开15份、车前子20份、一枝黄花10份、金樱子15份、牛膝6份、桃仁15份、蒲公英15份、鸭跖草20份、鱼腥草13份、灯芯草10份、川楝子15份、甘草5份，能治疗慢性前列腺炎。

Description

一种治疗慢性前列腺炎药物
技术领域
本发明涉及一种中药制剂，尤其涉及一种治疗慢性前列腺炎药物。
背景技术
慢性前列腺炎是男性一大健康问题，是泌尿外科医师所面临的棘手病症之一，它是50岁以下男性最常见的泌尿外科疾患，每年约有200万门诊病人。最近，据流行病学估计，其发病率为5％～8.8％。在美国，每个泌尿外科医师平均每年发现173例新病人。目前急需一种治疗慢性前列腺炎的药物。
发明内容
发明目的：本发明的目的在于提供一种治疗慢性前列腺炎药物。
技术方案：一种治疗慢性前列腺炎药物，它由如下重量份数的原料制备得到：黄皮叶20份、绿衣枳壳22份、诃子叶25份、百部还魂24份、乳白香青20份、雪里开15份、车前子20份、一枝黄花10份、金樱子15份、牛膝6份、桃仁15份、蒲公英15份、鸭跖草20份、鱼腥草13份、灯芯草10份、川楝子15份、甘草5份。
所述治疗慢性前列腺炎药物在制备治疗慢性前列腺炎药物中的应用。
黄皮叶为芸香科植物黄皮的叶片。疏风解表，除痰行气。治温病身热，咳嗽哮喘，气胀腹痛，黄肿，疟疾，小便不利，热毒疥癞等功效。
绿衣枳壳为芸香科植物枸橼Poncirustrifoliata(L.)Raf.的果实。行气宽中，消食，化痰。用于胸腹痞满胀痛、食积不化、痰饮、胃下垂。
诃子叶为使君子科植物诃子的叶片。降气化痰，止泻痢。治疗痰咳不止；外泻；外痢。
百部还魂为三白草科植物裸蒴的全草或叶。治跌打损伤。
乳白香青为菊科植物乳白香青的干燥全草。活血散瘀，平肝潜阳，祛痰。外用止血。
雪里开为毛莨科植物单叶铁线莲的根或叶。行气活血，抗菌消炎，对头、胃、腹、肌肉及关节等疼痛均有止痛作用。亦治气管炎，疔疮肿毒，跌打损伤。其余药材为药典品种。
有益效果：前列腺炎在中医看来，其主要病因属于“精浊”的范畴，多由外感湿热毒邪、内伤酒食、纵欲无度所致，本发明黄皮叶、绿衣枳壳、诃子叶、百部还魂、乳白香青、雪里开、车前子清热解毒、分清泌浊为君药，一枝黄花、金樱子、牛膝、桃仁、蒲公英、鸭跖草、鱼腥草、灯芯草、川楝子清热燥湿、益气为臣药，土茯苓为佐使药，全方具有清热解毒、分清泌浊作用，治疗前列腺炎效果良好。
具体实施方式
以下通过实施例形式，对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
1、具体实施例1：称取黄皮叶20g、绿衣枳壳22g、诃子叶25g、百部还魂24g、乳白香青20g、雪里开15g、车前子20g、一枝黄花10g、金樱子15g、牛膝6g、桃仁15g、蒲公英15g、鸭跖草20g、鱼腥草13g、灯芯草10g、川楝子15g、甘草5g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。用于治疗慢性前列腺炎。
2、具体实施例2：称取黄皮叶20g、绿衣枳壳22g、诃子叶25g、百部还魂24g、乳白香青20g、雪里开15g、车前子20g、一枝黄花10g、金樱子15g、牛膝6g、桃仁15g、蒲公英15g、鸭跖草20g、鱼腥草13g、灯芯草10g、川楝子15g、甘草5g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，加淀粉，按常规工艺制粒，即得符合正常成人1天用量的颗粒剂。用于治疗慢性前列腺炎。
3、具体实施例3：称取黄皮叶20g、绿衣枳壳22g、诃子叶25g、百部还魂24g、乳白香青20g、雪里开15g、车前子20g、一枝黄花10g、金樱子15g、牛膝6g、桃仁15g、蒲公英15g、鸭跖草20g、鱼腥草13g、灯芯草10g、川楝子15g、甘草5g，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，加淀粉，按常规工艺制粒，压片，即可制得符合正常成人1天用量的片剂。用于治疗慢性前列腺炎。
4、本发明对前列腺炎的临床研究
病例选择：50例病人，年龄最小23岁,最大45岁；已婚22例，未婚28例；病程最短3个月，最长4年。
诊断标准：参照《中药新药临床研究指导原则》中关于“中药新药治疗慢性前列腺炎(非特异性)的临床研究指导原则”制定。1、有下尿路刺激症状及炎性反应或放射性疼痛症状。表现为不同程度的尿频、尿急、尿痛,尿道灼热和尿道滴白,会阴部坠胀疼痛,2、前列腺触诊质地饱满或软硬不均、或有炎性结节,可有局限性压痛,大小可增大、正常或缩小。3、前列腺液(ESP)镜检示WBC>10个/HP,卵磷脂小体减少或消失。凡具备1和2、3中的任何1项即可确诊。
纳入标准为符合诊断标准,年龄22～60岁。排除标准为急性前列腺炎、良性前列腺增生症、前列腺癌、神经源性膀胱、尿道畸形或狭窄及严重神经官能症患者。合并尿路感染、尿路结石等者,有严重肝肾功能不全、心功能不全等者,过敏体质者。
治疗方法：按上述实施例2颗粒剂的制备方法制备样品，口服，一次一包，一日三次，一个月为一个疗程，间隔1周再行第2个疗程。治疗2个疗程后统计疗效。治疗期间均禁食酒、辛辣燥热、肥甘厚腻之品及刺激性食品,保持大便通畅,不长途乘骑自行车,禁忌手淫,坚持有规律地性生活。
疗效标准：根据国家中医药管理局发布的<<中医病证诊断疗效标准>>中”精浊”的疗效标准制定。临床治愈:症状消失,前列腺液检查正常。显效:症状消失或明显改善,前列腺液检查明显好转。有效:症状有改善,前列腺液检查有好转。无效:症状及前列腺液检查无改善。
治疗结果：临床治愈17例,显效19例,有效10例,无效4例,总有效率92％，使用中无毒副作用。

Claims (2)

1.一种治疗慢性前列腺炎药物，其特征在于，它由如下重量份数的原料制备得到：黄皮叶20份、绿衣枳壳22份、诃子叶25份、百部还魂24份、乳白香青20份、雪里开15份、车前子20份、一枝黄花10份、金樱子15份、牛膝6份、桃仁15份、蒲公英15份、鸭跖草20份、鱼腥草13份、灯芯草10份、川楝子15份、甘草5份。
2.如权利要求1所述治疗慢性前列腺炎药物在治疗慢性前列腺炎药物中的应用。
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CN104116952A (zh) * 2014-07-16 2014-10-29 吴凤金 一种治疗慢性前列腺炎的药物组合物
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