CN104338052A - 治疗脑血栓的中药配方 - Google Patents

治疗脑血栓的中药配方 Download PDF

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CN104338052A
CN104338052A CN201410515540.3A CN201410515540A CN104338052A CN 104338052 A CN104338052 A CN 104338052A CN 201410515540 A CN201410515540 A CN 201410515540A CN 104338052 A CN104338052 A CN 104338052A
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赵霞
刘维宏
邱正奭
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赵霞
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Abstract

本发明公开了一种治疗脑血栓的中药配方,由以下重量份数的中药原料配制而成:石菖蒲8-11份、天麻8-10份、山萸肉7-9份、川芎9-11份、丹参10-12份、鸡内金8-10份、槐花8-11份、麦冬10-12份、白芍10-12份、牛膝10-12份、防风7-9份、白术7-12份、红花8-12份、马鞭草8-12份、活血珠8-11份、枸杞子6-9份、麦芽7-9份、胆南星7-10份、龟板6-8份、乌梢蛇5-7份和全蝎5-7份,本发明的中药配方,补气祛邪,滋养肝肾,破血逐瘀,活血通络,疏通脑脉,治疗脑血栓具有较好的效果。

Description

治疗脑血栓的中药配方
技术领域
[0001] 本发明属于中医中药技术领域,特别涉及一种治疗脑血栓的中药配方。
背景技术
[0002] 脑血栓形成是脑梗死最常见的类型。是脑动脉主干或皮质支动脉粥样硬化导致血管增厚、管腔狭窄闭塞和血栓形成,引起脑局部血流减少或供血中断,脑组织缺血缺氧导致软化坏死出现局灶性神经系统症状。
[0003] 其病变范围一般为2-20毫米,其中以2-4毫米者最为多见。临床上患者多无明显症状,约有3/4的患者无病灶性神经损害症状,或仅有轻度注意力不集中、记忆力下降、轻度头痛头昏、眩晕、反应迟钝等症状。该病的诊断主要为CT或MRI检查。而轻度脑血栓如果成为多发性的,则可影响脑功能,导致智力进行性衰退,最后导致脑血管性痴呆。脑血栓形成多在安静或睡眠中发病,部分病例有短暂性脑缺血发作(TIA)前驱症状如肢体麻木无力等,突然出现偏侧上下肢麻木无力、口眼歪斜、言语不清等症状。
[0004] 脑血栓的治疗主要有中、西医两种治疗方法,西医治疗主要有扩张血管剂、降压药和抗血小板凝聚剂等药物,这些药副作用较大,长期使用会给人体器官带来不同程度的伤害。中医溶栓疗法能活血化瘀、疏通脑脉,从根本上解决脑血栓的问题,毒副作用小,治后不易复发,被大多数的患者所接受。
发明内容
[0005] 本发明提供一种治疗脑血栓的中药配方,通过中药调理,补气祛邪,滋养肝肾,破血逐瘀,活血通络,疏通脑脉,治疗脑血栓具有较好的效果。
[0006] 本发明的治疗脑血栓的中药配方,其特征在于由以下重量份数的中药原料配制而成:石菖蒲8-11份、天麻8-10份、山萸肉7-9份、川弯9-11份、丹参10-12份、鸡内金8-10份、槐花8-11份、麦冬10-12份、白芍10-12份、牛膝10-12份、防风7-9份、白术7_12份、红花8-12份、马鞭草8-12份、活血珠8-11份、枸杞子6_9份、麦芽7_9份、胆南星7_10份、龟板6-8份、乌梢蛇5-7份和全蝎5-7份。
[0007] 作为优选,按如下重量份数配制:石菖蒲9份、天麻9份、山萸肉8份、川芎9份、丹参12份、鸡内金9份、槐花10份、麦冬11份、白芍11份、牛膝11份、防风8份、白术9份、红花12份、马鞭草10份、活血珠9份、枸杞子8份、麦芽8份、胆南星9份、龟板7份、乌梢蛇6份和全蝎6份。
[0008] 本发明的中药,按下述步骤制备:
[0009] (I)按上述重量份称取石菖蒲、天麻、山萸肉、川弯、丹参、鸡内金、槐花、麦冬、白芍、牛膝、防风、白术、红花、马鞭草、活血珠、枸杞子、麦芽和胆南星放入砂锅里,然后加入饮用水,液面超出药材6-8倍量的蒸馏水,武火煮开后,改用文火煎煮2-3小时后,提取;再加入5-6倍量的蒸馏水,武火煮开后,文火煎煮2-2.5小时后,提取;最后加入3-4倍量的蒸馏水,武火煮开后,文火煎煮1.5-2小时后,提取;合并三次提取液,过滤,浓缩成40°C下相对密度为1.10-1.13的膏状;
[0010] (2)按上述重量份称取龟板、乌蛸蛇和全蝎,研末,过180目筛,备用;
[0011] (3)将步骤(1)-(2)制得的稠膏、细粉混合,制成6g蜜丸。
[0012] 上述方法制备的蜜丸,每日三次、每次一粒,饭后服用。
[0013] 药理分析:
[0014] 石菖蒲:化湿开胃,开窍豁痰,醒神益智。用于脘痞不饥,噤口下痢,神昏癫痫,健忘耳聋。理气,活血,散风,去湿。治癫痫,痰厥,热病神昏,健忘,气闭耳聋,心胸烦闷,胃痛,腹痛,风寒湿痹,痈疽肿毒,跌打损伤。
[0015] 天麻:甘,平;入肝经;息风,定惊。治眩晕眼黑,头风头痛,肢体麻木,半身不遂,语言蹇涩,小儿惊痫动风。
[0016] 山萸肉:别称山茱萸、山芋肉、山于肉等,补益肝肾;收敛固脱。主治头晕目眩;耳聋耳鸣;腰膝酸软;跹精滑精;小便频数;虚汗不止;妇女崩漏;内热消渴;温肝补肾,除一切风,止月经过多,治老人尿频。
[0017] 川芎:味辛,性温,归肝、胆、心经,气香升散,具有活血行气,祛风止痛的功效。
[0018] 丹参:根入药,含丹参酮,为强壮性通经剂,有祛瘀、生新、活血、调经等效用,为妇科要药,主治子宫出血,月经不调,血瘀,腹痛,经痛,经闭,庙痛。对治疗冠心病有良好效果。此外亦治神经性衰弱失眠,关节痛,贫血,乳腺炎,淋巴腺炎,关节炎,疮疖痛肿,丹毒,急慢性肝炎,肾孟肾炎,跌打损伤,晚期血吸虫病肝脾肿大,癫癎。外用又可洗漆疮。
[0019] 鸡内金:甘,平。归脾、胃、小肠、膀胱经;功效:消食健胃助消化,涩精止遗。可以促进胃液分泌,提高胃酸度及消化力,使胃运动功能明显增强,胃排空加快。涩精止遗。
[0020] 槐花:味苦、性微寒,归肝、大肠经;入血敛降,体轻微散;具有凉血止血,清肝泻火的功效;主治肠风便血,痔血,血痢,尿血,血淋,崩漏,吐血,衄血,肝火头痛,目赤肿痛,喉痹,失音,痈疽疮疡。
[0021] 麦冬:甘,微苦,微寒。归心、肺、胃经;养阴生津,润肺清心。用于肺燥干咳,阴虚痨嗽,喉痹咽痛,津伤口渴,内热消渴,心烦失眠,肠燥便秘。
[0022] 白芍:性凉,味苦酸,微寒,具有补血养血、平抑肝阳、柔肝止痛。敛阴止汗等功效,适用于阴虚发热、月经不调、胸腹胁肋疼痛、四肢挛急,泻痢腹痛、自汗盗汗、崩漏、带下等症。芍药甙有抗菌、解热、抗炎、增加冠状动脉流量、改善心肌营养血流、扩张血管、对抗急性心肌缺血、抑制血小板聚集、镇静、镇痛、解痉、抗溃疡、调节血糖的作用。白芍煎剂能抑制痢疾杆菌、肺炎链球菌、大肠杆菌、伤寒杆菌、溶血性链球菌、绿脓杆菌等。
[0023] 牛膝:苦;酸;性平,入肝、肾经;祛风,活血祛瘀。
[0024] 防风:味辛;甘;性微温。归经:膀胱经;肺经;脾经;肝经;功效:祛风解表、胜湿止痛、解痉、止痒。主治:外感风寒;头痛身痛;风湿痹痛;骨节酸痛;腹痛泄泻;肠风下血;破伤风;风疹瘙痒;疮疡初起。
[0025] 白术:白术具有健脾益气,燥湿利水,止汗,安胎的功效,用于脾虚食少,腹胀泄泻,痰饮眩悸,水肿,自汗,胎动不安。《医学启源》记载:“除湿益燥,和中益气,温中,去脾胃中湿,除胃热,强脾胃,进饮食,安胎。”
[0026] 红花:活血通经,散瘀止痛,有助于治经闭、痛经、恶露不行、胸痹心痛、瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛疗效。有活血化瘀,散湿去肿的功效。
[0027]马鞭草:性凉,味微葳,有凉血、散瘀、通经、清热、解毒、止痒、驱虫、消胀的功效。
[0028] 活血珠:该药具有清热解毒、消肿散结、舒筋活血的功效。用于痈肿疗毒、淋巴结核、跌打损伤、蛇虫咬伤等。
[0029] 枸杞:药理作用:对免疫功能有影响作用。性味:枸杞:甘,平。枸杞叶:苦、甘;性凉。功能:枸杞子:养肝,滋肾,润肺。枸杞叶:补虚益精,清热明目。
[0030] 麦芽:行气消食,健脾开胃,退乳消胀。食积不消,脘腹胀痛,脾虚食少,乳汗郁积,乳房胀痛,妇女断乳。
[0031] 胆南星:清火化痰,镇惊定痼。治中风痰迷,惊风癫痫,痰火喘嗽,头风眩晕。
[0032] 龟板:滋阴,潜阳,补肾,健骨;主治:治肾阴不足,骨蒸劳热,吐血,衄血,久咳,遗精,崩漏,带下,腰痛,骨痿,阴虚风动,久痢,久疟,痔疮,小儿因门不合。
[0033] 乌梢蛇:味甘,性平;归肝、脾经;善行走窜;具有祛风湿,通经络,熄风止痉,止痒解毒的功效;主治风湿顽痹,麻木拘挛,中风口眼歪斜,半身不遂,小儿惊风,抽搐痉挛,破伤风,麻风疥癣,瘰疬恶疮。
[0034] 全蝎:主要药用成分为蝎毒素,据《本草纲目》和《中国药典》载,全蝎具有“熄风镇痉、消炎攻毒、通络止痛”功能;主治“小儿惊风、抽搐痉挛、皮肤病、心脑血管病、炎症、乙肝、肿瘤”等病。
[0035] 本发明的中药配方,选用山萸肉、白术、防风、龟板、枸杞,补气祛邪、补益肝肾,配伍丹参、川芎、乌蛸蛇、全蝎,通经络、活血化瘀;胆南星、活血珠、天麻,清热解毒、安神定惊,治疗脑血栓,标本兼治,具有更好的治疗效果。
[0036] 疗效判断:
[0037] 脑血栓的主要临床症状有:偏侧上下肢麻木无力、口眼歪斜、言语不清。
[0038] 痊愈:肢体肌力恢复,行动正常,语言表达流利,无障碍。
[0039] 好转:上下肢麻木无力改善,口眼歪斜改善。
[0040] 无效:诸症无改善。
[0041] 治疗结果:脑血栓患者342例,服用本发明的药物,痊愈293例,占85.7%,好转25例,占7.3%,有效率为93%。
[0042] 附几例病例作进一步说明:
[0043] 病例1:郑X X,女,68岁,右上下肢瘫痪,伴眩晕、呕吐、小便失禁三天。住院查体BP180/11OmmHg,神志清,头颅CT检查,脑血管堵塞,静脉注射的同时,服用本发明药剂,每次一粒,每日三次,治疗14天后,病人头痛、眩晕、呕吐消除,又治疗14天后,病人肌力恢复正常,复查BP150/90mmHg,头颅CT、心电图、血常规、肝肾功能、血脂血糖、血流变均恢复正常,痊愈出院,半年后回访无复发。
[0044] 病例2:黄XX,男,65岁,晨起时感觉上下肢活动不灵,伴饮水呛咳。来院检查,查体BP170/100mmHg,心肺腹无异常,头颅CT示右脑梗塞,心电图示慢冠,血常规、肝肾功能正常,空腹血糖8.3mmol/L,胆固醇6.5mmol/L,甘油三酯2.9mmol/L。住院后在静脉输液的基础上同时服用本发明药剂,每日三次,每次I粒,治疗14天后病人饮水饮食无呛咳,四肢活动正常,继续治疗14天,复查头颅CT、心电图、血常规、肝肾功能、血脂血糖均恢复正常,痊愈出院。一年无复发。
具体实施方式
[0045] 实施例1
[0046] 石菖蒲9份、天麻9份、山萸肉8份、川弯9份、丹参12份、鸡内金9份、槐花10份、麦冬11份、白芍11份、牛膝11份、防风8份、白术9份、红花12份、马鞭草10份、活血珠9份、枸杞子8份、麦芽8份、胆南星9份、龟板7份、乌梢蛇6份和全蝎6份。
[0047] 本发明的中药,按下述步骤制备:
[0048] (I)按上述重量份称取石菖蒲、天麻、山萸肉、川弯、丹参、鸡内金、槐花、麦冬、白芍、牛膝、防风、白术、红花、马鞭草、活血珠、枸杞子、麦芽和胆南星放入砂锅里,然后加入饮用水,液面超出药材6-8倍量的蒸馏水,武火煮开后,改用文火煎煮2-3小时后,提取;再加入5-6倍量的蒸馏水,武火煮开后,文火煎煮2-2.5小时后,提取;最后加入3-4倍量的蒸馏水,武火煮开后,文火煎煮1.5-2小时后,提取;合并三次提取液,过滤,浓缩成40°C下相对密度为1.10-1.13的膏状;
[0049] (2)按上述重量份称取龟板、乌蛸蛇和全蝎,研末,过180目筛,备用;
[0050] (3)将步骤(1)-(2)制得的稠膏、细粉混合,制成6g蜜丸。
[0051] 上述方法制备的蜜丸,每日三次、每次一粒,饭后服用。

Claims (2)

1.一种治疗脑血栓的中药配方,其特征在于由以下重量份数的中药原料配制而成:石菖蒲8-11份、天麻8-10份、山萸肉7-9份、川弯9-11份、丹参10-12份、鸡内金8-10份、槐花8-11份、麦冬10-12份、白芍10-12份、牛膝10-12份、防风7-9份、白术7_12份、红花8-12份、马鞭草8-12份、活血珠8-11份、枸杞子6_9份、麦芽7-9份、胆南星7_10份、龟板6-8份、乌梢蛇5-7份和全蝎5-7份。
2.根据权利要求1所述的治疗脑血栓的中药配方,其特征在于由以下重量份数的中药原料配制而成:石菖蒲9份、天麻9份、山萸肉8份、川芎9份、丹参12份、鸡内金9份、槐花10份、麦冬11份、白芍11份、牛膝11份、防风8份、白术9份、红花12份、马鞭草10份、活血珠9份、枸杞子8份、麦芽8份、胆南星9份、龟板7份、乌梢蛇6份和全蝎6份。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169288A (zh) * 2015-10-27 2015-12-23 张先雷 一种治疗痰湿阻络型脑梗死患者言语含糊不清的中药汤剂
CN105194407A (zh) * 2015-10-28 2015-12-30 张先雷 一种治疗痰湿阻络型脑梗死患者言语含糊不清的中药胶囊剂及其制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612324A (zh) * 2009-07-09 2009-12-30 蒋保珍 治疗脑血栓的药物
CN104013836A (zh) * 2014-06-26 2014-09-03 王芬 一种治疗脑中风后遗症的中药组合物
CN104043054A (zh) * 2014-06-26 2014-09-17 袁国防 一种治疗中风后遗症的药物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101612324A (zh) * 2009-07-09 2009-12-30 蒋保珍 治疗脑血栓的药物
CN104013836A (zh) * 2014-06-26 2014-09-03 王芬 一种治疗脑中风后遗症的中药组合物
CN104043054A (zh) * 2014-06-26 2014-09-17 袁国防 一种治疗中风后遗症的药物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105169288A (zh) * 2015-10-27 2015-12-23 张先雷 一种治疗痰湿阻络型脑梗死患者言语含糊不清的中药汤剂
CN105194407A (zh) * 2015-10-28 2015-12-30 张先雷 一种治疗痰湿阻络型脑梗死患者言语含糊不清的中药胶囊剂及其制备方法

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