CN105342943A - Gel containing Chinese herbal medicine extract and preparation method of gel - Google Patents
Gel containing Chinese herbal medicine extract and preparation method of gel Download PDFInfo
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- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a gel containing a Chinese herbal medicine extract and a preparation method of the gel, and aims at providing a gel which is moist in skin touch, safe, mild, and good in moisture effect, and is thawed once touched. According to the technical main points, the gel contains the following components in percentage by mass: 0.4%-0.6% of polyglycerylmetharylate and propylene glycol, 0.22%-0.34% of carbomer, 0.22%-0.34% of triethanolamine, 0.64%-0.96% of beta-glucan, 0.024%-0.5% of sodium hyaluronate, 1.2%-1.8% of 2-hydroxyethylurea, 0.32%-0.48% of jojoba wax PEG-120 esters, 0.08%-0.12% of disodium ethylene diamine tetraacetate, 1.2%-1.8% of glyceryl polyether-26, 0.16%-0.24% of methylparaben, 0.0048%-0.0072% of essence, 0.024%-0.036% of PEG-40 hydrogenated castor oil, 8%-12% of Alpine glacier water, 0.008%-0.012% of a wetting regulator, 0.01%-3% of a selaginella tamariscina extracting solution, 0.01%-3% of a chamomile extract and the balance of water.
Description
Technical field
The invention discloses a kind of condensation, specifically, be a kind of condensation containing Chinese herbal medicine extract, the invention still further relates to the preparation method of this condensation; Belong to technical field of skin care.
Background technology
Along with the raising of people's living standard, the maintenance of women to self is also more and more paid attention to.Liking to be beautiful is the nature of each woman, everyone thinks perpetual youth, forever have skin at an early age, and along with modern industry is to the pollution of living environment, earth environment pollutes day by day serious, also more and more serious to the injury of human skin, add the development of modern science and technology, computer, mobile phone are almost the instruments of everyone indispensability, human skin is all among various radiation and pollution all day, skin of face allergy, pruritus, dry situation get more and more, and skin aging accelerates, and people have to seek various skin-protection product and carry out delaying skin aging.At present, market there is various moisture retention water, moisturizer, moisturiser, effect is different, the people of different skin quality needs the product selecting corresponding effect according to the skin quality of oneself, and along with the arriving of autumn and winter season, the skin of majority is all subject to seasonal effect and becomes very dry, and miscellaneous water conservation water, Ruzhong composition is different, most of cosmetics are all be made up of pure chemistry composition, feel after fresh out of that skin water moistens, after more than one hour, due to volatilization or the stimulation of chemical composition, skin all can become dry usually, and the human body skin that seems is aged simple and unadorned, life-time service, also can cause skin hydropenia, irreversible damage is produced to skin.
Existing condensation kind is a lot of on the market at present, and the skin moistening mainly tending to basis does not focus on safety and skinfeel when using, and moistening effect is undesirable.
Summary of the invention
For the problems referred to above, the object of this invention is to provide a kind of skinfeel water profit, one touches and namely changes, and safety is gentle, the condensation containing Chinese herbal medicine extract that moistening effect is good, the invention still further relates to the preparation method of this condensation.
For solving the problems of the technologies described above, first technical scheme provided by the invention is such:
Containing the condensation of Chinese herbal medicine extract, calculate by gross mass 100%, each component and mass percentage content as follows:
Preferably, above-mentioned a kind of condensation containing Chinese herbal medicine extract, calculates by gross mass 100%, each component and mass percentage content as follows:
More have choosing, above-mentioned a kind of condensation containing Chinese herbal medicine extract, described wet adjusting agent is one of them or combination in any of Xylitol-based glucoside or anhydro xylitol or xylitol.
The above-mentioned condensation preparation method containing Chinese herbal medicine extract provided by the invention
1) each component is taken;
2) will take essence is dissolved in Cremophor RH40, obtains prefabrication 1;
3) deionized water will be added agitated kettle, carbomer under agitation, add ethoxy urea, reed fragrant plant oil, hyaluronate sodium, Jojoba wax PEG-120 esters, EDETATE SODIUM, glycerin polyether-26, methyl hydroxybenzoate again, at the uniform velocity stir and be warming up to 80-85 DEG C, insulated and stirred 10-15min, prefabrication 2;
4) prefabrication 2 is cooled to 65-70 DEG C, adds beta glucan and triethanolamine, insulated and stirred 10-15min; Continue to be cooled to 40-45 DEG C, add prefabrication 1, Alps glacial water, moistening adjusting agent, Herba Selaginellae extracting solution and camomile extract, insulated and stirred 10-15min, detect qualified rear discharging
Compared with prior art, each component scientific compatibility provided by the invention, reasonable formula, sense of touch is fine, and skinfeel is soft, and one brush can change water, with the moisturizing of rear water profit, safe and non-stimulating non-stimulated.
In prescription, each component effect is as follows:
Reed fragrant plant oil: water miscible viscous liquid, pH value is close to the acidity of human body skin, and multi-functional skin moisturizer, can improve skinfeel and lubricity.
Carbomer: the water-soluble thickener of high-quality, has extremely short rheological characteristic, high transparency, high endurance of cutting, fabulous high-temperature stability, the salubrious water profit of skinfeel, the primary raw material of providing water.
Triethanolamine: splendid gentle nertralizer.
Beta glucan: skinfeel is splendid is the active component of multi-functional moisturizing, reparation.
Hyaluronate sodium: internationally recognized nature moisturizing factor, give product water and moisten soft skinfeel, compact skin, permanent moisturizing, prevents dehydration, and histiocyte regenerates.
Ethoxy urea: splendid wetting agent, can provide efficient moisture-retention effect simultaneously again without sticky feel to skin care item.
Jojoba wax PEG-120 esters: wetting agent, keeps continuous skin moistening.
EDETATE SODIUM: a kind of excellent chelating agen.
Glycerin polyether-26: can form double-deck moisture film, effectively pin moisture, be skin emolliency, lubricant, has superior sense of touch, without greasy feeling after using.
Methyl hydroxybenzoate: broad-spectrum antibacterial agent, is easy to various compound compatibility.
Cremophor RH40: efficient solubilizing agents, compatibilization ability is strong, and consumption is low, and low-temperature transparent degree is good.
Alps glacial water: from alpine glacial water, there is moisture-keeping function.
Xylitol-based glucoside (with) anhydro xylitol (with) xylitol: the moisturizing ingredient of natural botanical source, improves the moisture of epidermis, strengthens skin barrier effect, reduce water loss.
Herba Selaginellae (Herba Selaginellae) extracting solution: natural component, gentle non-stimulated, water suction efficiently and lock water function, supplement the normal moisture of skin tender to reach the permanent water of skin.
Camomile extract: natural component, gentle non-stimulated, calm Beauty promise effect.
Nonanedioyl Diglycocol potassium, suppresses the injury of radical pair skin, suppresses the irregular growth of horn cell in hair follicle, improves moisture-retaining capacity, suppresses the activity of TYR enzyme, effectively blocks melanic formation;
Radix Paeoniae Alba extract, analgesia whitening;
Folium Aloe extracting solution, forming the smooth hygroscopic mem-brane of one deck at skin surface, promoting beautiful feeling and the flexibility of formula when not increasing viscosity, because being rich in polysaccharide and the effect of releiving.
Detailed description of the invention
Below in conjunction with detailed description of the invention; claim of the present invention is described in further detail; but do not form any limitation of the invention, the amendment of anyone limited number of time made in the claims in the present invention protection domain, still within claims of the present invention.
Embodiment 1
A kind of condensation containing Chinese herbal medicine extract provided by the invention, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.6g, carbomer 0.22g, triethanolamine 0.34g, beta glucan 0.64g, hyaluronate sodium 0.5g, ethoxy urea 1.2g Jojoba wax PEG-120 esters 0.48g, EDETATE SODIUM 0.08g, glycerin polyether-261.8g, methyl hydroxybenzoate 0.16g, essence 0.0072g, Cremophor RH40 0.024g, Alps glacial water 12g, xylitol 0.008g, Herba Selaginellae extracting solution 3g, camomile extract 0.01g, surplus is water.
Embodiment 2
Another kind provided by the invention is containing the condensation of Chinese herbal medicine extract, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.4g, carbomer 0.34g, triethanolamine 0.22g, beta glucan 0.96g, hyaluronate sodium 0.024g, ethoxy urea 1.8g Jojoba wax PEG-120 esters 0.32g, EDETATE SODIUM 0.12g, glycerin polyether-261.2g, methyl hydroxybenzoate 0.24g, essence 0.0048g, Cremophor RH40 0.036g, Alps glacial water 8g, anhydro xylitol 0.012g, Herba Selaginellae extracting solution 0.01g, camomile extract 3g, surplus is water.
Embodiment 3
Another kind provided by the invention is containing the condensation of Chinese herbal medicine extract, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.45g, carbomer 0.30g, triethanolamine 0.26g, beta glucan 0.85g, hyaluronate sodium 0.1g, ethoxy urea 1.6g Jojoba wax PEG-120 esters 0.38g, EDETATE SODIUM 0.10g, glycerin polyether-261.45g, methyl hydroxybenzoate 0.22g, essence 0.0055g, Cremophor RH40 0.030g, Alps glacial water 9g, anhydro xylitol 0.011g, Herba Selaginellae extracting solution 0.5g, camomile extract 2g, surplus is water.
Embodiment 4
A kind of condensation containing Chinese herbal medicine extract provided by the invention, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.55g, carbomer 0.26g, triethanolamine 0.30g, beta glucan 0.75g, hyaluronate sodium 0.3g, ethoxy urea 1.4g Jojoba wax PEG-120 esters 0.40g, EDETATE SODIUM 0.09g, glycerin polyether-261.55g, methyl hydroxybenzoate 0.18g, essence 0.0065g, Cremophor RH40 0.028g, Alps glacial water 11g, Xylitol-based glucoside 0.009g, Herba Selaginellae extracting solution 2g, camomile extract 0.5g, surplus is water.
Embodiment 5
A kind of condensation containing Chinese herbal medicine extract provided by the invention, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.5g, carbomer 0.28g, triethanolamine 0.28g, beta glucan 0.8g, hyaluronate sodium 0.03g, ethoxy urea 1.5g, Jojoba wax PEG-120 esters 0.4g, EDETATE SODIUM 0.1g, glycerin polyether-261.5g, methyl hydroxybenzoate 0.2g, essence 0.006g, Cremophor RH40 0.03g, Alps glacial water 0.01g, Xylitol-based glucoside 0.008, anhydro xylitol 0.001, xylitol 0.01g, Herba Selaginellae (Herba Selaginellae) extracting solution 0.01g, camomile extract 0.01g, surplus is water.
In embodiment 1 to 5 provided by the invention, any one group of condensation preparation method containing Chinese herbal medicine extract, comprises the steps: successively
1) each component is taken by one group of mass number any in embodiment 1 to 5;
2) will take essence is dissolved in Cremophor RH40, obtains prefabrication 1;
3) deionized water will be added agitated kettle, carbomer under agitation, add ethoxy urea, reed fragrant plant oil, hyaluronate sodium, Jojoba wax PEG-120 esters, EDETATE SODIUM, glycerin polyether-26, methyl hydroxybenzoate again, at the uniform velocity stir and be warming up to 80-85 DEG C, insulated and stirred 10-15min, prefabrication 2;
4) prefabrication 2 is cooled to 65-70 DEG C, adds beta glucan and triethanolamine, insulated and stirred 10-15min; Continue to be cooled to 40-45 DEG C, add prefabrication 1, Alps glacial water profit, wet adjusting agent, Herba Selaginellae extracting solution and camomile extract, insulated and stirred 10-15min, detects qualified rear discharging.
Embodiment 6
A kind of condensation containing Chinese herbal medicine extract provided by the invention, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.55g, carbomer 0.26g, triethanolamine 0.30g, beta glucan 0.75g, hyaluronate sodium 0.3g, ethoxy urea 1.4g Jojoba wax PEG-120 esters 0.40g, EDETATE SODIUM 0.09g, glycerin polyether-261.55g, methyl hydroxybenzoate 0.18g, essence 0.0065g, Cremophor RH40 0.028g, Alps glacial water 11g, Xylitol-based glucoside 0.009g, Herba Selaginellae extracting solution 2g, camomile extract 0.5g, nonanedioyl Diglycocol potassium 1.5g, Radix Paeoniae Alba extract 0.5g, Folium Aloe extracting solution 0.8g, surplus is water.
Embodiment 7
A kind of condensation containing Chinese herbal medicine extract provided by the invention, calculate by gross mass 100g, be made up of following component: reed fragrant plant oil 0.5g, carbomer 0.28g, triethanolamine 0.28g, beta glucan 0.8g, hyaluronate sodium 0.03g, ethoxy urea 1.5g, Jojoba wax PEG-120 esters 0.4g, EDETATE SODIUM 0.1g, glycerin polyether-261.5g, methyl hydroxybenzoate 0.2g, essence 0.006g, Cremophor RH40 0.03g, Alps glacial water 0.01g, Xylitol-based glucoside 0.008, anhydro xylitol 0.001, xylitol 0.01g, Herba Selaginellae (Herba Selaginellae) extracting solution 0.01g, camomile extract 0.01g, nonanedioyl Diglycocol potassium 1.5g, Radix Paeoniae Alba extract 0.5g, Folium Aloe extracting solution 0.8g, surplus is water.
In embodiment 6 to 7 provided by the invention, any one group of condensation preparation method containing Chinese herbal medicine extract, comprises the steps: successively
1) each component is taken by one group of mass number any in embodiment 1 to 5;
2) will take essence is dissolved in Cremophor RH40, obtains prefabrication 1;
3) deionized water will be added agitated kettle, carbomer under agitation, add ethoxy urea, reed fragrant plant oil, hyaluronate sodium, Jojoba wax PEG-120 esters, EDETATE SODIUM, glycerin polyether-26, methyl hydroxybenzoate again, at the uniform velocity stir and be warming up to 80-85 DEG C, insulated and stirred 10-15min, prefabrication 2;
4) prefabrication 2 is cooled to 65-70 DEG C, adds beta glucan and triethanolamine, insulated and stirred 10-15min; Continue to be cooled to 40-45 DEG C, add prefabrication 1, Alps glacial water profit, wet adjusting agent, Herba Selaginellae extracting solution and camomile extract, nonanedioyl Diglycocol potassium, Radix Paeoniae Alba extract, Folium Aloe extracting solution, insulated and stirred 10-15min, detects qualified rear discharging.
Wherein:
The extracting method of Herba Selaginellae extracting solution is as follows: get 10g Herba Selaginellae decoction pieces, be placed in flask, add 95wt% alcoholic solution 100g, after soaking 0.5h, reflux, extract, 1h under 80 DEG C of water bath condition, extraction fluid, medicinal residues continue to add 95wt% alcoholic solution 100g, reflux, extract, 1h at 80 DEG C, obtains secondary raffinate, merges two batches of extracting solution.Use buchner funnel to filter Herba Selaginellae extracting solution, obtain clear liquor (Herba Selaginellae extracting solution).
The extracting method of camomile extract is as follows: get 10g Flos Matricariae chamomillae decoction pieces, be placed in flask, add 70wt% alcoholic solution 100g, after soaking 0.5h, reflux, extract, 1h under 70 DEG C of water bath condition, extraction fluid, medicinal residues continue to add 70wt% alcoholic solution 100g, reflux, extract, 1h at 70 DEG C, obtains secondary raffinate, merges two batches of extracting solution.Use buchner funnel to filter Flos Matricariae chamomillae extracting solution, obtain clear liquor (Flos Matricariae chamomillae extracting solution).By clear liquor, be placed in vacuum drying oven, in temperature 80 DEG C, continue dry 48h under the condition of vacuum-0.05MPa, obtain desciccate, pulverize, obtain camomile extract powder.
Radix Paeoniae Alba extract: get 10g Radix Paeoniae decoction pieces, be placed in flask, add 70wt% alcoholic solution 100g, after soaking 0.5h, reflux, extract, 1h under 80 DEG C of water bath condition, extraction fluid, medicinal residues continue to add 70wt% alcoholic solution 100g, reflux, extract, 1h at 80 DEG C, obtains secondary raffinate, merges two batches of extracting solution.Use buchner funnel to filter Radix Paeoniae extracting solution, obtain clear liquor.By clear liquor, be placed in vacuum drying oven, in temperature 80 DEG C, continue dry 48h under the condition of vacuum-0.05MPa, obtain desciccate, pulverize, obtain Radix Paeoniae Alba extract powder.
Aloe extraction solution: get fresh aloe, chopping, puts in the cloth bag after cleaning-sterilizing, squeezes out aloe juice, and filters with 80 order nylon gauzes, obtains Aloe original juice, i.e. Aloe extraction solution.
In order to prove advantage of the present invention, applicant carries out the test of 3T3 cytotoxicity to condensation provided by the invention, and obtaining median lethal concentration is 36494 μ g/ml, and under 1% concentration, (the general permeability of cosmetics) cytoactive does not affect; Meanwhile, calculating LD50 by Oral toxicity and Cytotoxic prediction model is 5261.9mg/kg, classifies this product not at the row of acute oral toxicity classification, namely do not predict acute oral toxicity according to GHS; And certain famous product calculates LD50 by Oral toxicity and Cytotoxic prediction model is on the market 638.12mg/kg, be classified as the fourth stage according to GHS this product acute oral toxicity of classifying, namely swallow harmful (per os).
Claims (4)
1., containing a condensation for Chinese herbal medicine extract, it is characterized in that, calculate by gross mass 100%, comprise following each component, each constituent mass percentage ratio is as follows:
2. a kind of condensation containing Chinese herbal medicine extract according to claim 1, is characterized in that, calculate by gross mass 100%, each component and mass percentage content as follows:
3. a kind of condensation containing Chinese herbal medicine extract according to claims 1 or 2, is characterized in that, described wet adjusting agent is one of them or combination in any of Xylitol-based glucoside or anhydro xylitol or xylitol.
4. prepare a kind of condensation containing Chinese herbal medicine extract described in claims 1 or 2, it is characterized in that, comprise the steps: successively
1) each component is taken by the mass number described in claims 1 or 2;
2) will take essence is dissolved in Cremophor RH40, obtains prefabrication 1;
3) deionized water will be added agitated kettle, carbomer under agitation, add ethoxy urea, reed fragrant plant oil, hyaluronate sodium, Jojoba wax PEG-120 esters, EDETATE SODIUM, glycerin polyether-26, methyl hydroxybenzoate again, at the uniform velocity stir and be warming up to 80-85 DEG C, insulated and stirred 10-15min, prefabrication 2;
4) prefabrication 2 is cooled to 65-70 DEG C, adds beta glucan and triethanolamine, insulated and stirred 10-15min; Continue to be cooled to 40-45 DEG C, add prefabrication 1, Alps glacial water, moistening adjusting agent, Herba Selaginellae extracting solution and camomile extract, insulated and stirred 10-15min, detect qualified rear discharging.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105748354A (en) * | 2016-03-09 | 2016-07-13 | 广东芭薇生物科技股份有限公司 | Facial mask liquid and preparation method thereof |
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| CN106619304A (en) * | 2016-12-31 | 2017-05-10 | 广州品爵生物科技有限公司 | Composition for repairing skin surface lipid film and preparation method and application thereof |
| CN114081850A (en) * | 2021-12-27 | 2022-02-25 | 广州源燊创生物科技有限公司 | Efficient cosmetic humectant |
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