CN105748378A - Hand protective cream containing ceramide - Google Patents
Hand protective cream containing ceramide Download PDFInfo
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- CN105748378A CN105748378A CN201610288772.9A CN201610288772A CN105748378A CN 105748378 A CN105748378 A CN 105748378A CN 201610288772 A CN201610288772 A CN 201610288772A CN 105748378 A CN105748378 A CN 105748378A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention provides a hand protective cream containing ceramide. The hand protective cream is prepared from the following raw materials in parts by weight: 2-8 parts of an emulsifying agent, 0.2-2 parts of a co-emulsifier, 5-35 parts of propylene glycol dicaprate, 0.2-2 parts of a skin absorption accelerant, 5-25.5 parts of a hydrating agent, 0.05-0.5 part of a thickening agent, 0.1-0.8 part of a PH regulating agent, 2-8 parts of vegetable oil, 0.2-1.5 parts of a preservative, 2-11 parts of plant extracts, 1-7 parts of ceramide and 0.1-78 parts of deionized water, wherein the vegetable oil is a mixture of tamanu oil, and shea butter; the plant extracts are a mixture of a rhizoma drynariae extract and a camomile extract. The hand protective cream disclosed by the invention is mild and non-irritating, has notable efficacies of preventing and treating agnail, moisturizing and locking water, and can solve the problems that due to finger agnail caused by damaged sebum, living of people is distracted, and the application of the tamanu oil in cosmetics is limited.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of hand cream containing ceramide.
Background technology
At present, the aesthetic function of hands, just quietly rise and be day by day accepted and attention.The fine and slim hands that a pair of is slender, fine and smooth, ruddy, not only give health, soft and slender, dexterous sense, more add woman charm.In the winter time; the both hands of many people are easily chapped, agnail, dry, chilblain; the both hands of especially many housewifves often to contact the articless for washing such as liquid detergent, detergent, handwashing liquid; owing to articles for washing dirt-removing power is strong; easily washing the sebum on skin off, cause that skin lacks protection, moisture evaporates; not only can play agnail, be also easy to eczema.Agnail is medically called agnail, refers to the near-end from nail fold or lateral margin cracking and the fritter Yangtze River Delta shape epidermis that tilts, time have pain.If agnail is ignored, impact is life usually, if pulling out, not only aching, finger sometimes also can be made bloodstained, and serious also results in skin infection, and little barbule brings many worries to the life of people.But the product being specifically designed for the nursing of finger agnail at present on the market is very few.
Fine jade precipice Caulis et folium euphorbiae milii oil is also referred to as Yi Nuofeilun (Tamanu) oil, and famous with its repairing and protection effect, it can speed up the growth of skin histology, and his-and-hers watches leatherware has excellent repair.But, fine jade precipice Caulis et folium euphorbiae milii oil, because having special overpowering odor and close to ater, adds that its price is higher, therefore its application in cosmetics is restricted.
Ceramide, also known as sphingolipid, is present in a kind of lipid of skin, is a kind of water-soluble grease metallic substance, nature moisturizing factor, for oiliness skin-active composition important in horny layer, can set up and maintain the barrier of skin lipids, fill up excessive the caused cutin loss gap of cleaning.
Summary of the invention
In order to overcome the deficiencies in the prior art, the present invention provides a kind of hand cream containing ceramide, this hand cream gentleness does not stimulate, the effect making to improve on consumption basis its reparation sebum film of its effective ingredient fine jade precipice Caulis et folium euphorbiae milii oil can reduced, solve the finger agnail that causes because sebum film is impaired, cause people to live the problem of puzzlement and limitation problem applied by fine jade precipice Caulis et folium euphorbiae milii oil in cosmetics.
The present invention is achieved through the following technical solutions:
The invention discloses a kind of hand cream containing ceramide, described hand cream includes the raw material of following weight portion: emulsifying agent 2～8 parts, co-emulsifier 0.2～2 part, skin emollient 5～35 parts, skin absorption promoter 0.2～2 part, wetting agent 5～25.5 parts, thickening agent 0.05～0.5 part, acid-base modifier 0.1～0.8 part, vegetable oil 2～8 parts, preservative 0.2～1.5 part, plant extract 2～11 parts, Cer EOS～7 part, deionized water 0.1～78 part；Described vegetable oil is the mixture of fine jade precipice Caulis et folium euphorbiae milii oil, shea butter, and described plant extract is the mixture of Rhizoma Drynariae extract, camomile extract.
The sebum that hand sebaceous gland is secreted naturally defines one layer of adipose membrane, and it is the second barrier of protection skin, it is possible to reduce horny layer moisture evaporates, it is ensured that its suitable water content.Sebum film is once suffer that destruction can make the immunity degradation of skin and lock water function weaken and form the dry and sensitive of skin.Skin edge part this with regard to especially easy season cracking, small crackle is rubbed increase, then occurs as soon as agnail.Contained by hand cream of the present invention, epidermal tissue is had good promotion regeneration by effective ingredient fine jade precipice Caulis et folium euphorbiae milii oil, it is obvious to the repair of sebum film, especially with ceramide with the use of time, ceramide can promote and improve this repair of fine jade precipice Caulis et folium euphorbiae milii oil, both Synergistics, both the repair of sebum film was strengthened, also further enhanced the moistening effect of skin；Shea butter strengthens cell regeneration and skin moisturizing lock water effect, moreover it is possible to promote finger blood vessel microcirculation, simultaneously works as reduction fine jade precipice Caulis et folium euphorbiae milii oil viscosity, promotes the absorption of other effective ingredient；Rhizoma Drynariae extract and camomile extract can promote finger blood vessel microcirculation, accelerate the absorption of effective ingredient, suppress the intrusion of extraneous harmful substance, it is suppressed that skin allergy simultaneously.
Further, described hand cream also includes 0.5～5 part of cetearyl alcohol.This hand cream adds appropriate cetearyl alcohol, formula emulsification can be made better, strengthen the stability of formula.
Further, emulsifying agent described in hand cream of the present invention is one or both in sorbitan stearate, polysorbate-60.
Further, co-emulsifier described in hand cream of the present invention is glyceryl stearate, PEG-100 stearate.
Further, skin emollient described in hand cream of the present invention is one or more in lanoline, vaseline, polydimethylsiloxane, isopropyl myristate.
Further, skin absorption promoter described in hand cream of the present invention is laurocapram.
Further, wetting agent described in hand cream of the present invention is one or more in hyaluronate sodium, glycerol, propylene glycol.
Further, thickening agent described in hand cream of the present invention is the mixture of carbomer, xanthan gum, and the weight part ratio of the two is 0.1～0.25:0.1～0.25, and described acid-base modifier is triethanolamine.
Further, fine jade precipice Caulis et folium euphorbiae milii described in hand cream of the present invention is oily, the weight part ratio of shea butter is 0.1～1:2～5, shea butter mixes with fine jade precipice Caulis et folium euphorbiae milii oil can reduce fine jade precipice Caulis et folium euphorbiae milii oil viscosity, so as to be easier to be less readily available for absorption by the skin, both are ideal with this proportioning effect.
Further, Rhizoma Drynariae extract described in hand cream of the present invention, camomile extract weight part ratio be 2～7:2～4.
A kind of hand cream containing ceramide of the present invention, has following beneficial effect:
1, hand cream of the present invention can not affect its to the basis of the repair of sebum film on be substantially reduced fine jade precipice Caulis et folium euphorbiae milii oil make consumption, reduce the impact on cosmetics of its abnormal smells from the patient and color, reduce cost simultaneously；
2, contained by hand cream of the present invention effective ingredient fine jade precipice Caulis et folium euphorbiae milii oil with ceramide with the use of time, can Synergistic, both the repair of sebum film was strengthened, also further enhanced the moistening effect of skin；
3, hand cream of the present invention has a significant preventive and therapeutic action to because of sebum film is impaired, skin allergy causes finger agnail, and skin has good moisturizing, lock water effect；
4, hand cream gentleness of the present invention does not stimulate, it is easy to skin absorption, has good stability, and is also applicable to the nursing of toe agnail.
Detailed description of the invention
In order to make those skilled in the art be more fully understood that technical scheme, below in conjunction with embodiment, technical scheme is described in further detail.
In following embodiment, described raw material is commercially available prod.
Components Name used in following example is international cosmetic raw material name (InternationalNomenclatureCosmeticIngredient, INCI) title of defined, such as " glyceryl stearate, PEG-100 stearate ", referring to glyceryl stearate and the mixture of PEG-100 stearate, " Bis(hydroxymethyl)imidazolidinyl urea, iodine propilolic alcohol butyl mephenesin Carbamate " refers to Bis(hydroxymethyl)imidazolidinyl urea and the mixture of iodine propilolic alcohol butyl mephenesin Carbamate.
Table 1 below is the composition of the formula material of hand cream embodiment of the present invention and comparative example and percentage by weight thereof:
Table 1
Embodiment 5 moistening effect evaluation
Test philosophy
Difference according to cosmetic composition moisture absorption, performance of keeping humidity, different wetting agent molecules is different to the active force of hydrone, absorbs moisture different with the ability keeping moisture.Moisture is had sealing process by oil content, can prevent scattering and disappearing of moisture.Hygroscopic effect power is big, and water molecules power is strong, absorbs and the amount of maintenance moisture is also relatively larger, and closure is good, also lacking of moisture loss.Utilize adhesive tape to imitate the biomaterial of horny layer, epidermis etc., adhesive tape is coated with cosmetics, simulates the application feature of actual cosmetics.When constant temperature and humidity after certain time, weigh sample and place the of poor quality of front and back, obtain the loss of sample size, it is possible to calculate the effect of moisturizing ingredient moisturizing.
Moisturizing rate computing formula:
Moisturizing rate=(M2 M0)/(M1 M0) × 100%
In formula:
M0: hollow plate quality/g
M1: glass sheet quality/g after application of sample
M2: quality/g after placing in exsiccator some hours
Test its moisturizing rate in 4h and 8h when relative humidity is 60%.
Test result is table 2 below such as:
Table 2 hand cream is in the moisturizing rate of RH60%
Can be seen that from above table, hand skin is all had certain moistening effect by embodiment 1～3 hand cream and comparative example 1～2 hand cream, but the moistening effect of hand skin is substantially better than comparative example 1 (containing only there being fine jade precipice Caulis et folium euphorbiae milii oil by embodiment 1～3 hand cream, shea butter, Rhizoma Drynariae extract) and comparative example 2 (containing only there being ceramide, camomile extract) moistening effect of hand cream, thus illustrate, the effective ingredient that hand cream of the present invention contains: fine jade precipice Caulis et folium euphorbiae milii oil, shea butter, Rhizoma Drynariae extract, ceramide, there is between camomile extract mutual synergism, hand cream of the present invention has significant moisturizing, lock water effect.
Embodiment 6 clinical efficacy evaluation
Choosing the housewife of 80 25～50 years old age brackets as experimental subject, be arbitrarily divided into 8 groups, respectively the hand cream of embodiment 1～4 on probation and comparative example 1～2, result adopts grading scheme, and every result of use total score is 5 points, and 5 are divided into effect obvious, and trier is the most satisfied；4 are divided into effect better, and trier can accept；3 points and following be that trier can not accept almost without effect, be below every average, concrete outcome is in Table 3:
Table 3 hand cream resultant effect is investigated
In use there is not anaphylaxis and other toxic reactions in trier.
Hand agnail symptom (is dried by embodiment 1～4 hand cream and comparative example 1～2 hand cream and certain commercially available moisture-keeping efficacy hand cream as can be seen from the above results, red and swollen, skin lesion) all have some improvement, but the improvement of hand agnail symptom is substantially better than comparative example 1 (containing only there being fine jade precipice Caulis et folium euphorbiae milii oil by embodiment 1～4 hand cream, shea butter, Rhizoma Drynariae extract) and comparative example 2 (containing only there being ceramide, camomile extract) the improvement effect of hand cream and certain commercially available moisture-keeping efficacy hand cream, the effective ingredient that hand cream of the present invention contains thus is described: fine jade precipice Caulis et folium euphorbiae milii oil, shea butter, Rhizoma Drynariae extract, ceramide, there is between camomile extract synergistic function, hand cream of the present invention has significant prevention and treatment finger agnail effect.
Embodiment 7 hand cream formulation stability is evaluated
According to QB/T1857 2013 " skin moistening cream " standard, embodiment 1～4 hand cream is carried out physicochemical property experiment test, and result is table 4 below such as:
Table 4 hand cream physicochemical property test result
After embodiment 1～4 hand cream continues placement 2 months, embodiment 1～3 test heat-resisting, cold-resistant is still without obvious oil-water separation phenomenon, but there is slight oil-water separation phenomenon in embodiment 4 (without cetearyl alcohol) hand cream, thus illustrate this hand cream adds appropriate cetearyl alcohol, the stability of formula can be strengthened.
Embodiment described above only have expressed the several embodiments of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that, for the person of ordinary skill of the art, without departing from the inventive concept of the premise, it is also possible to making some deformation and improvement, these broadly fall into protection scope of the present invention.
Claims (10)
1. the hand cream containing ceramide, it is characterised in that described hand cream includes the raw material of following weight portion:
Emulsifying agent 2～8 parts, co-emulsifier 0.2～2 part, skin emollient 5～35 parts, skin absorption promoter 0.2～2 part, wetting agent 5～25.5 parts, thickening agent 0.05～0.5 part, acid-base modifier 0.1～0.8 part, vegetable oil 2～8 parts, preservative 0.2～1.5 part, plant extract 2～11 parts, Cer EOS～7 part, deionized water 0.1～78 part；Described vegetable oil is the mixture of fine jade precipice Caulis et folium euphorbiae milii oil, shea butter, and described plant extract is the mixture of Rhizoma Drynariae extract, camomile extract.
2. hand cream according to claim 1, it is characterised in that described hand cream also includes 0.5～5 part of cetearyl alcohol.
3. hand cream according to claim 1 and 2, it is characterised in that described emulsifying agent is one or both in sorbitan stearate, polysorbate-60.
4. hand cream according to claim 1 and 2, it is characterised in that described co-emulsifier is glyceryl stearate, PEG-100 stearate.
5. hand cream according to claim 1 and 2, it is characterised in that described skin emollient is one or more in lanoline, vaseline, polydimethylsiloxane, isopropyl myristate.
6. hand cream according to claim 1 and 2, it is characterised in that described skin absorption promoter is laurocapram.
7. hand cream according to claim 1 and 2, it is characterised in that described wetting agent is one or more in hyaluronate sodium, glycerol, propylene glycol.
8. hand cream according to claim 1 and 2, it is characterised in that described thickening agent is the mixture of carbomer, xanthan gum, and the weight part ratio of the two is 0.1～0.25:0.1～0.25, described acid-base modifier is triethanolamine.
9. hand cream according to claim 1 and 2, it is characterised in that described fine jade precipice Caulis et folium euphorbiae milii is oily, the weight part ratio of shea butter is 0.1～1:2～5.
10. hand cream according to claim 1 and 2, it is characterised in that described Rhizoma Drynariae extract, camomile extract weight part ratio be 2～7:2～4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610288772.9A CN105748378A (en) | 2016-05-04 | 2016-05-04 | Hand protective cream containing ceramide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610288772.9A CN105748378A (en) | 2016-05-04 | 2016-05-04 | Hand protective cream containing ceramide |
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| CN105748378A true CN105748378A (en) | 2016-07-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610288772.9A Withdrawn CN105748378A (en) | 2016-05-04 | 2016-05-04 | Hand protective cream containing ceramide |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107126405A (en) * | 2017-05-05 | 2017-09-05 | 小牛哞哞母婴用品(深圳)有限公司 | It is a kind of to aim at protection children sebum film, the skin care item containing milk extract |
| CN107582490A (en) * | 2017-10-10 | 2018-01-16 | 胡江宇 | A kind of hand lotion containing ginger composition |
| CN108498382A (en) * | 2018-06-28 | 2018-09-07 | 武汉百思凯瑞生物科技有限公司 | A kind of moisturizing conveys nano-composition and its preparation method and application altogether |
| CN108685807A (en) * | 2018-09-08 | 2018-10-23 | 山东卓健医疗科技有限公司 | Anti-bacterium hand cream |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908301A (en) * | 2012-11-15 | 2013-02-06 | 李欣欣 | Anti-chapping hand cream and preparation method thereof |
| CN103263371A (en) * | 2013-05-23 | 2013-08-28 | 江苏隆力奇生物科技股份有限公司 | Skin care product comprising nano tamanu oil emulsion |
-
2016
- 2016-05-04 CN CN201610288772.9A patent/CN105748378A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908301A (en) * | 2012-11-15 | 2013-02-06 | 李欣欣 | Anti-chapping hand cream and preparation method thereof |
| CN103263371A (en) * | 2013-05-23 | 2013-08-28 | 江苏隆力奇生物科技股份有限公司 | Skin care product comprising nano tamanu oil emulsion |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107126405A (en) * | 2017-05-05 | 2017-09-05 | 小牛哞哞母婴用品(深圳)有限公司 | It is a kind of to aim at protection children sebum film, the skin care item containing milk extract |
| CN107582490A (en) * | 2017-10-10 | 2018-01-16 | 胡江宇 | A kind of hand lotion containing ginger composition |
| CN108498382A (en) * | 2018-06-28 | 2018-09-07 | 武汉百思凯瑞生物科技有限公司 | A kind of moisturizing conveys nano-composition and its preparation method and application altogether |
| CN108685807A (en) * | 2018-09-08 | 2018-10-23 | 山东卓健医疗科技有限公司 | Anti-bacterium hand cream |
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Application publication date: 20160713 |