CN105287249A - Hand sanitizer and preparation method thereof - Google Patents
Hand sanitizer and preparation method thereof Download PDFInfo
- Publication number
- CN105287249A CN105287249A CN201510738443.5A CN201510738443A CN105287249A CN 105287249 A CN105287249 A CN 105287249A CN 201510738443 A CN201510738443 A CN 201510738443A CN 105287249 A CN105287249 A CN 105287249A
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- China
- Prior art keywords
- parts
- handwashing liquid
- purified salt
- preparation
- deionized water
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Abstract
The invention discloses a hand sanitizer and a preparation method thereof. The hand sanitizer comprises the following components in parts by weight: 1-3 parts of refined salt, 5-11 parts of polyoxyethylene fatty alcohol sodium sulfate, 2-6 parts of cocamidopropyl betaine, 0.5-1.5 parts of cocoanut fatty acid diethanolamide and 75-87 parts of deionized water. The hand sanitizer has an effect of rinsing easily while having a certain viscosity, and also has a moisture preserving function and can relieve hand chaps and promote chap healing while achieving the effects of decontaminating, cleaning, eradicating odors and killing bacteria.
Description
Technical field
The present invention relates to articles for washing technical field, be specifically related to a kind of handwashing liquid and preparation method thereof.
Background technology
In recent years, along with the day by day raising of living standard, handwashing liquid enters huge numbers of families, the major function of handwashing liquid plays the effect of cleaning skin, also part handwashing liquid is had to have the effect of sterilization, containing a certain amount of ethanol in its handwashing liquid composition, sterilized by ethanol, but alcoholic content has certain zest to hand skin, hand moisture is taken away in the process of ethanol volatilization, make hand dry, therefore, for addressing this problem, more surfactant is separately with the addition of in most of handwashing liquid, hand is made to possess moisture, but the adding of exhibiting high surface activating agent, also cause and not easily rinse, waste water problem, therefore, existing most of handwashing liquid can not reach sterilization, moisturizing, the effect that easy flushing takes into account.
Summary of the invention
In view of this, the application provides a kind of handwashing liquid and preparation method thereof, and described handwashing liquid is while having certain viscosity, also there is the effect of easily rinsing, reaching decontamination, clean, eliminate the unusual smell, sterilize while, there is moisture-keeping functions, hand can be alleviated chap, promote to chap healing.
For solving above technical problem, technical scheme provided by the invention is a kind of handwashing liquid, described handwashing liquid is counted by weight and is comprised: purified salt 1-3 parts, polyoxyethylenated alcohol sodium sulfate 5-11 parts, cocamido propyl betaine 2-6 parts, cocoanut fatty acid diethanolamide 0.5-1.5 parts, deionized water 75-87 parts.
Preferably, purified salt 1.5-2.5 parts, polyoxyethylenated alcohol sodium sulfate 6-9 parts, cocamido propyl betaine 3-5 parts, cocoanut fatty acid diethanolamide 0.8-1.2 parts, deionized water 78-84 parts.
More preferred, purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts.
Preferably, in described purified salt, the content of sodium chloride is not less than 98.5%.
Technical scheme also provides a kind of preparation method of above-mentioned handwashing liquid, and described preparation method comprises the following steps:
(1) aseptic deionized water is added agitated kettle;
(2) added at least at twice by purified salt in the deionized water described in step (1), be heated to more than 70 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is cooled to less than 50 DEG C, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, insulated and stirred is cooling discharging after 15-30 minutes, ageing 20-30 hours, packs after the assay was approved and get final product again.
Preferably, 75 DEG C are heated in described step (1).
Preferably, in described step (3), purified salt solution is cooled to 45 DEG C.
Preferably, insulated and stirred cooling discharging after 15-25 minutes in described step (3).
More preferred, the middle insulated and stirred of described step (3) cooling discharging after 20 minutes.
Preferably, in described step (3), digestion time is 24 hours.
In technical scheme, in described purified salt, the content of sodium chloride is for being not less than 98.5%, has sterilizing function, have thickening power simultaneously in handwashing liquid, and thickening effect is good, and easy to use.
The anion surfactant of described polyoxyethylenated alcohol sodium sulfate to be a kind of abnormal smells from the patient be typical soap taste, has that performance gentleness, zest are little, the effect such as foaming abundancy, exquisiteness.
Described cocamido propyl betaine is an extremely gentle amphoteric surfactant, colourless or pale yellow transparent thick liquid, and to skin, eye mucosa is non-stimulated, without anaphylactic reaction, its foam stabilization, exquisiteness, wash rear smooth moistening and do not tighten; Composite with anion surfactant, under the condition of pH5.5-6.5, can improve material body viscosity, thickening effect is obvious, is more close to the physiology acid-base value of normal skin under this pH value condition.
Described cocoanut fatty acid diethanolamide is a kind of non-ionic surface active agent, has abundant foam, surely steeps foam enhancing, and character is watery, as clear as crystal.
Described polyoxyethylenated alcohol sodium sulfate and sodium chloride combine, and can reach good thickening power in aqueous, and thickening effect is relevant with the content of sodium chloride, and in clear water, polyoxyethylenated alcohol sodium sulfate can not realize thickening.
In addition, in technical scheme, adding of purified salt, play thickening power on the one hand, on the other hand, also there is the effect of sterilizing, purified salt, polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide is adopted to carry out combining the handwashing liquid obtained, while there is certain viscosity, also there is the effect of easily rinsing, reaching decontamination, clean, eliminate the unusual smell, sterilize while, there is moisture-keeping functions, hand can be alleviated chap, promote to chap healing.
Detailed description of the invention
In order to make those skilled in the art understand technical scheme of the present invention better, below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment one
Handwashing liquid A-E described in the present embodiment:
Meter comprises by weight: purified salt 3 parts, polyoxyethylenated alcohol sodium sulfate 11 parts, cocamido propyl betaine 6 parts, cocoanut fatty acid diethanolamide 1.5 parts, deionized water 87 parts, is numbered handwashing liquid A.
Meter comprises by weight: purified salt 1 part, polyoxyethylenated alcohol sodium sulfate 5 parts, cocamido propyl betaine 2 parts, cocoanut fatty acid diethanolamide 0.5 part, deionized water 75 parts, is numbered handwashing liquid B.
Meter comprises by weight: purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts, is numbered handwashing liquid C.
Meter comprises by weight: purified salt 2.5 parts, polyoxyethylenated alcohol sodium sulfate 9 parts, cocamido propyl betaine 5 parts, cocoanut fatty acid diethanolamide 1.2 parts, deionized water 84 parts, is numbered handwashing liquid D.
Meter comprises by weight: purified salt 1.5 parts, polyoxyethylenated alcohol sodium sulfate 6 parts, cocamido propyl betaine 3 parts, cocoanut fatty acid diethanolamide 0.8 part, deionized water 78 parts, is numbered handwashing liquid E.
Wherein, in described purified salt, the content of sodium chloride is 98.5%.
Above-mentioned handwashing liquid A-E is all formed by following steps preparation:
(1) aseptic deionized water is added agitated kettle;
(2) added at twice by purified salt in the deionized water described in step (1), be heated to 75 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is cooled to 45 DEG C, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, insulated and stirred is cooling discharging after 20 minutes, ageing 24 hours, packs after the assay was approved and get final product again.
Above-mentioned handwashing liquid A-E is carried out Indexs measure, and adopt commercially available handwashing liquid as a control group, testing result is in table 1 simultaneously.
Table 1 embodiment one Indexs measure result
Wherein: after moisture preserving time refers to and uses handwashing liquid, hand moisture reduces, and retains the time for the treatment of required for its natural drying.
Embodiment two
Handwashing liquid I, II, III described in the present embodiment:
Meter comprises by weight: purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts.
Above-mentioned handwashing liquid I, II, III is formed by following steps preparation:
(1) aseptic deionized water is added agitated kettle;
(2) added at twice by purified salt in the deionized water described in step (1), be heated to 75 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is lowered the temperature, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, insulated and stirred is cooling discharging after 20 minutes, then ageing 24 hours, packs after the assay was approved and get final product.
In the preparation method of wherein handwashing liquid I, II, III, in step (3), purified salt solution is cooled to 50 DEG C, 47 DEG C, 45 DEG C respectively, and all the other preparation processes are all identical.
Described handwashing liquid I, II, III is carried out Indexs measure, and adopt commercially available handwashing liquid as a control group, testing result is in table 2 simultaneously.
Table 2 embodiment two Indexs measure result
Wherein: after moisture preserving time refers to and uses handwashing liquid, hand moisture reduces, and retains the time for the treatment of required for its natural drying.
Embodiment three
Handwashing liquid 1,2,3,4 described in the present embodiment:
Meter comprises by weight: purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts.
Above-mentioned handwashing liquid 1,2,3,4 is formed by following steps preparation:
(1) aseptic deionized water is added agitated kettle;
(2) added at twice by purified salt in the deionized water described in step (1), be heated to 75 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is cooled to 45 DEG C, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, cooling discharging after insulated and stirred, then ageing 24 hours, pack after the assay was approved and get final product.
In the preparation method of wherein handwashing liquid 1,2,3,4, in step (3), the time of insulated and stirred is respectively 15 minutes, 20 minutes, 25 minutes, 30 minutes, and all the other preparation processes are all identical.
Described handwashing liquid 1,2,3,4 is carried out Indexs measure, and adopt commercially available handwashing liquid as a control group, testing result is in table 3 simultaneously.
Table 3 embodiment three Indexs measure result
Wherein: after moisture preserving time refers to and uses handwashing liquid, hand moisture reduces, and retains the time for the treatment of required for its natural drying.
Embodiment four
Handwashing liquid a, b, c described in the present embodiment:
Meter comprises by weight: purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts.
Above-mentioned handwashing liquid a, b, c are formed by following steps preparation:
(1) aseptic deionized water is added agitated kettle;
(2) added at twice by purified salt in the deionized water described in step (1), be heated to 75 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is cooled to 45 DEG C, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, insulated and stirred is cooling discharging after 20 minutes, then ageing, packs after the assay was approved and get final product.
In the preparation method of wherein handwashing liquid a, b, c, in step (3), the time of ageing is respectively 20 hours, 24 hours, 30 hours, and all the other preparation processes are all identical.
Described handwashing liquid a, b, c are carried out Indexs measure, and adopt commercially available handwashing liquid as a control group, testing result is in table 4 simultaneously.
Table 4 embodiment four-index testing result
Wherein: after moisture preserving time refers to and uses handwashing liquid, hand moisture reduces, and retains the time for the treatment of required for its natural drying.
Below be only the preferred embodiment of the present invention, it should be pointed out that above-mentioned preferred implementation should not be considered as limitation of the present invention, protection scope of the present invention should be as the criterion with claim limited range.For those skilled in the art, without departing from the spirit and scope of the present invention, can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (10)
1. a handwashing liquid, it is characterized in that: described handwashing liquid is counted by weight and comprised: purified salt 1-3 parts, polyoxyethylenated alcohol sodium sulfate 5-11 parts, cocamido propyl betaine 2-6 parts, cocoanut fatty acid diethanolamide 0.5-1.5 parts, deionized water 75-87 parts.
2. a kind of handwashing liquid according to claim 1, it is characterized in that: purified salt 1.5-2.5 parts, polyoxyethylenated alcohol sodium sulfate 6-9 parts, cocamido propyl betaine 3-5 parts, cocoanut fatty acid diethanolamide 0.8-1.2 parts, deionized water 78-84 parts.
3. a kind of handwashing liquid according to claim 2, is characterized in that: purified salt 2 parts, polyoxyethylenated alcohol sodium sulfate 7 parts, cocamido propyl betaine 4 parts, cocoanut fatty acid diethanolamide 1 part, deionized water 81 parts.
4. a kind of handwashing liquid according to any one of claim 1-3, is characterized in that: in described purified salt, the content of sodium chloride is not less than 98.5%.
5. a preparation method for the handwashing liquid described in any one of claim 1-4, is characterized in that: described preparation method comprises the following steps:
(1) aseptic deionized water is added agitated kettle;
(2) added at least at twice by purified salt in the deionized water described in step (1), be heated to more than 70 DEG C, dissolve, stir to obtain purified salt solution;
(3) purified salt solution described in step (2) is cooled to less than 50 DEG C, add polyoxyethylenated alcohol sodium sulfate, cocamido propyl betaine, cocoanut fatty acid diethanolamide, insulated and stirred is cooling discharging after 15-30 minutes, ageing 20-25 hours, packs after the assay was approved and get final product again.
6. the preparation method of a kind of handwashing liquid according to claim 5, is characterized in that: described step is heated to 75 DEG C in (1).
7. the preparation method of a kind of handwashing liquid according to claim 5, is characterized in that: in described step (3), purified salt solution is cooled to 45 DEG C.
8. the preparation method of a kind of handwashing liquid according to claim 5, is characterized in that: the middle insulated and stirred of described step (3) cooling discharging after 15-25 minutes.
9. the preparation method of a kind of handwashing liquid according to claim 8, is characterized in that: the middle insulated and stirred of described step (3) cooling discharging after 20 minutes.
10. the preparation method of a kind of handwashing liquid according to claim 5, is characterized in that: in described step (3), digestion time is 24 hours.
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CN201510738443.5A CN105287249A (en) | 2015-11-04 | 2015-11-04 | Hand sanitizer and preparation method thereof |
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CN201510738443.5A CN105287249A (en) | 2015-11-04 | 2015-11-04 | Hand sanitizer and preparation method thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106109363A (en) * | 2016-08-27 | 2016-11-16 | 祝家程 | A kind of handwashing liquid |
CN106137872A (en) * | 2016-08-24 | 2016-11-23 | 祝家程 | A kind of disinfection hand cleanser |
CN106511427A (en) * | 2016-12-27 | 2017-03-22 | 四川默森药业有限公司 | Composition for skin mucous membrane disinfection and preparation method of composition |
CN107669553A (en) * | 2017-10-31 | 2018-02-09 | 腾冲高黎贡山生态食品发展有限公司 | A kind of fragrant fruit hand cleanser and preparation method thereof |
CN112972281A (en) * | 2021-03-02 | 2021-06-18 | 上海应用技术大学 | Disinfectant-grade hand sanitizer containing salicylic acid microcapsules and preparation method thereof |
CN113350226A (en) * | 2021-06-04 | 2021-09-07 | 利康医药科技江苏有限公司 | Novel antibacterial hand sanitizer and preparation method thereof |
CN113576969A (en) * | 2021-08-09 | 2021-11-02 | 利康医药科技江苏有限公司 | Traditional Chinese medicine compound antibacterial hand sanitizer and preparation method thereof |
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CN103222942A (en) * | 2013-05-17 | 2013-07-31 | 江阴中利生物技术有限公司 | Chinese herbal medicine foot bath solution added with bamboo vinegar and preparation method thereof |
CN104666171A (en) * | 2015-01-22 | 2015-06-03 | 海南师范大学 | Antibacterial hand sanitizer and preparation method thereof |
CN104922310A (en) * | 2015-05-21 | 2015-09-23 | 广东轻工职业技术学院 | Traditional Chinese medicine composition with bacteriostasis function and application of traditional Chinese medicine composition to daily necessities |
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CN101735898A (en) * | 2010-01-04 | 2010-06-16 | 江苏中聿实业有限公司 | Indigowoad root liquid soap and production method thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106137872A (en) * | 2016-08-24 | 2016-11-23 | 祝家程 | A kind of disinfection hand cleanser |
CN106109363A (en) * | 2016-08-27 | 2016-11-16 | 祝家程 | A kind of handwashing liquid |
CN106511427A (en) * | 2016-12-27 | 2017-03-22 | 四川默森药业有限公司 | Composition for skin mucous membrane disinfection and preparation method of composition |
CN107669553A (en) * | 2017-10-31 | 2018-02-09 | 腾冲高黎贡山生态食品发展有限公司 | A kind of fragrant fruit hand cleanser and preparation method thereof |
CN112972281A (en) * | 2021-03-02 | 2021-06-18 | 上海应用技术大学 | Disinfectant-grade hand sanitizer containing salicylic acid microcapsules and preparation method thereof |
CN113350226A (en) * | 2021-06-04 | 2021-09-07 | 利康医药科技江苏有限公司 | Novel antibacterial hand sanitizer and preparation method thereof |
CN113576969A (en) * | 2021-08-09 | 2021-11-02 | 利康医药科技江苏有限公司 | Traditional Chinese medicine compound antibacterial hand sanitizer and preparation method thereof |
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Application publication date: 20160203 |