CN105247067A - 融合蛋白酶 - Google Patents
融合蛋白酶 Download PDFInfo
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- CN105247067A CN105247067A CN201480029964.7A CN201480029964A CN105247067A CN 105247067 A CN105247067 A CN 105247067A CN 201480029964 A CN201480029964 A CN 201480029964A CN 105247067 A CN105247067 A CN 105247067A
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- protease
- fusion
- protein
- bifunctional fusion
- fusion protease
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/485—Exopeptidases (3.4.11-3.4.19)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
- C12Y304/14011—Xaa-Pro dipeptidyl-peptidase (3.4.14.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- C12Y304/22—Cysteine endopeptidases (3.4.22)
- C12Y304/22028—Picornain 3C (3.4.22.28)
Landscapes
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
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- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13169173 | 2013-05-24 | ||
| EP13169173.5 | 2013-05-24 | ||
| EP13171191 | 2013-06-10 | ||
| EP13171191.3 | 2013-06-10 | ||
| US201361834100P | 2013-06-12 | 2013-06-12 | |
| US61/834100 | 2013-06-12 | ||
| EP13194053 | 2013-11-22 | ||
| EP13194053.8 | 2013-11-22 | ||
| US201361909412P | 2013-11-27 | 2013-11-27 | |
| US61/909412 | 2013-11-27 | ||
| PCT/EP2014/060696 WO2014187974A1 (en) | 2013-05-24 | 2014-05-23 | Fusion protease |
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|---|---|
| CN105247067A true CN105247067A (zh) | 2016-01-13 |
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| CN201480029964.7A Withdrawn CN105247067A (zh) | 2013-05-24 | 2014-05-23 | 融合蛋白酶 |
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| US (1) | US20160122793A1 (enExample) |
| EP (1) | EP3004369A1 (enExample) |
| JP (1) | JP2016518855A (enExample) |
| CN (1) | CN105247067A (enExample) |
| WO (2) | WO2014187974A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110128540A (zh) * | 2019-04-18 | 2019-08-16 | 江南大学 | 一种基于便携式血糖仪的广谱二抗 |
| CN112011497A (zh) * | 2020-08-28 | 2020-12-01 | 上海交通大学 | 分泌表达猪源性抗产肠毒素大肠杆菌k88菌毛单链抗体的重组乳酸乳球菌及其制备方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160060312A1 (en) | 2014-08-27 | 2016-03-03 | Cellivery Therapeutics, Inc. | Development of Protein-Based Biotherapeutics That Penetrates Cell-Membrane and Induces Anti-Pancreatic Cancer Effect - Improved Cell-Permeable Suppressor of Cytokine Signaling (iCP-SOCS3) Proteins, Polynucleotides Encoding the Same, and Anti-Pancreatic Cancer Compositions Comprising the Same |
| CN110592057B (zh) * | 2019-09-27 | 2022-01-28 | 昆明理工大学 | 嵌合裂解酶ILTphg和编码此酶的多核苷酸 |
| US20250122489A1 (en) * | 2023-10-16 | 2025-04-17 | Zhenyu Zhu | Protein Thermostability Reduction by Tag Fusion and Its Usage |
Family Cites Families (3)
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|---|---|---|---|---|
| CA1200773A (en) * | 1980-02-29 | 1986-02-18 | William J. Rutter | Expression linkers |
| US4769326A (en) * | 1980-02-29 | 1988-09-06 | The Regents Of The University Of California | Expression linkers |
| NZ236819A (en) * | 1990-02-03 | 1993-07-27 | Max Planck Gesellschaft | Enzymatic cleavage of fusion proteins; fusion proteins; recombinant dna and pharmaceutical compositions |
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2014
- 2014-05-23 WO PCT/EP2014/060696 patent/WO2014187974A1/en not_active Ceased
- 2014-05-23 US US14/889,993 patent/US20160122793A1/en not_active Abandoned
- 2014-05-23 EP EP14726158.0A patent/EP3004369A1/en not_active Withdrawn
- 2014-05-23 CN CN201480029964.7A patent/CN105247067A/zh not_active Withdrawn
- 2014-05-23 WO PCT/EP2014/060669 patent/WO2014187960A1/en not_active Ceased
- 2014-05-23 JP JP2016514440A patent/JP2016518855A/ja not_active Withdrawn
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110128540A (zh) * | 2019-04-18 | 2019-08-16 | 江南大学 | 一种基于便携式血糖仪的广谱二抗 |
| CN110128540B (zh) * | 2019-04-18 | 2021-12-14 | 江南大学 | 一种基于便携式血糖仪的二抗 |
| CN112011497A (zh) * | 2020-08-28 | 2020-12-01 | 上海交通大学 | 分泌表达猪源性抗产肠毒素大肠杆菌k88菌毛单链抗体的重组乳酸乳球菌及其制备方法 |
| CN112011497B (zh) * | 2020-08-28 | 2022-06-07 | 上海交通大学 | 分泌表达猪源性抗产肠毒素大肠杆菌k88菌毛单链抗体的重组乳酸乳球菌及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016518855A (ja) | 2016-06-30 |
| US20160122793A1 (en) | 2016-05-05 |
| WO2014187960A1 (en) | 2014-11-27 |
| WO2014187974A1 (en) | 2014-11-27 |
| EP3004369A1 (en) | 2016-04-13 |
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