CN105213271A - A kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization - Google Patents
A kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization Download PDFInfo
- Publication number
- CN105213271A CN105213271A CN201510735753.1A CN201510735753A CN105213271A CN 105213271 A CN105213271 A CN 105213271A CN 201510735753 A CN201510735753 A CN 201510735753A CN 105213271 A CN105213271 A CN 105213271A
- Authority
- CN
- China
- Prior art keywords
- parts
- sunscreen cream
- microcapsule
- repair function
- phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
Abstract
The present invention discloses a kind of preparation method of sunscreen cream containing repair function microcapsule after shining, first with maltodextrin, arabic gum, hydroxyethyl-cellulose, Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract, Cys and sorbester p17 for raw material preparation shine after repair function microcapsule; Again by described microcapsule and Oleum Cocois, lanoline, ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789,2-cyano group-3; 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester, vitamin E, deionized water, xanthan gum as raw material, prepare described sunscreen cream together with span 20.The present invention gets up to be added in sunscreen cream by repairing composition embedding after solarization by microcapsule technology, makes sunscreen cream play sun-proof and repair double effects after shining, and effectively avoids both to coexist and the bad interactive competition phenomenon that causes.
Description
Technical field
The invention belongs to sun-proof technical field, be specifically related to a kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization.
Background technology
UVA and UVB in sunlight can penetrate skin corium, and make skin produce sunburn, peel, tanned etc. shines rear phenomenon, and then makes skin old and feeble in advance, causes some irremediable injuries, if for a long time by the impact of UVA and UVB, also likely cause skin carcinoma to skin.
In order to prevent skin by tanned and sunburn, the sunscreen cream product that with the addition of sun-prevention component arises at the historic moment.Even if but use sunscreen cream to carry out how tight protection, also the injury that ultraviolet brings can not very be isolated, repairing after shining is reclamation activities important after long-time Exposure to Sunlight, but carry out repairing in short time only after solarization and just can play useful effect, if Exposure to Sunlight is repaired after a whole day again, good repairing effect will do not reached.
Current sunscreen cream function is comparatively single, only has sun-proof function, and not having sunscreen cream that is sun-proof and reparation double effects after shining concurrently commercially has sale, has certain gaps in market.But, existing sun-prevention component and rear the reparation between composition of solarization have certain reciprocal effect relation, namely when both coexist in a kind of product, certain negative function may be had, the sun-proof function of sunscreen cream is weakened, and make the system of sunscreen cream become unstable, be not easy evenly to be coated on skin.
Summary of the invention
For prior art above shortcomings, technical problem to be solved by this invention is: how to provide a kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization, in order to weaken sun-prevention component and to repair the bad reciprocal action relation between composition after shining, make the sunscreen cream containing the rear repair function microcapsule of solarization obtained have concurrently sun-proof and repair double effects after shining, and the problem of system instability can not be produced.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme: a kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization, comprises the steps:
1) microencapsulation material of following weight portion is taken: 20 ~ 30 portions of maltodextrins, 15 ~ 25 parts of arabic gums, 10 ~ 15 parts of hydroxyethyl-celluloses, 20 ~ 25 portions of Oleum Cocois, 5 ~ 15 parts of Oleum Hippophaes, 5 ~ 10 parts of Jojoba waxes, 3 ~ 5 parts of squalanes, 3 ~ 5 parts of vitamin Es, 2 ~ 4 parts of Radix Hamamelidis Mollis ethanol extract, 2 ~ 4 parts of Herba Portulacae ethanol extract, 1 ~ 5 part of peoniflorin, 2 ~ 6 parts of green tea ethanol extract, 1 ~ 3 part of Cys and 1 ~ 3 part of sorbester p17;
2) add in deionized water by the maltodextrin taken and arabic gum, heating for dissolving at 75 ~ 85 DEG C, is mixed with mixed solution A; Wherein, the volume of the deionized water added is 25 ~ 36 times of maltodextrin and arabic gum gross mass;
3) add the hydroxyethyl-cellulose weighed up in the mixed solution A prepared to step 1), after stirring, at 75 ~ 85 DEG C, supersound process 1 ~ 4min, obtains capsule wall solution B; Wherein, hyperacoustic power is 400 ~ 550W;
4) Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract and the Cys mix homogeneously that will take, under the water bath condition of 60 ~ 80 DEG C after supersound process 5 ~ 10min, with high speed dispersor dispersion 3 ~ 6min, obtain mixture C; Wherein the rotating speed of dispersion machine is 2000 ~ 2500r/min;
5) in mixture C, add span, use homogenizer homogenizing 5 ~ 15min, obtain emulsifying homogeneous liquid D; Wherein homogenization pressure is 55 ~ 60MPa;
6) by after capsule wall solution B and emulsifying homogeneous liquid D mix homogeneously, after first using high speed dispersor dispersion 2 ~ 5min, then carry out homogenizing 2 ~ 7min, obtain mixed liquor E; Wherein, the rotating speed of high speed dispersor is 1500 ~ 2000r/min, and homogenization pressure is 40 ~ 50MPa;
7) spraying dry is carried out to mixed liquor E, obtain shining rear repair function microcapsule; Wherein, controlling inlet temperature is 175 ~ 178 DEG C, and leaving air temp is 85 ~ 92 DEG C, feed rate 4.00 ~ 4.45mL/min;
8) the sunscreen cream raw material of following weight portion is taken: repair function microcapsule, 30 ~ 40 portions of Oleum Cocois, 15 ~ 20 parts of lanolines, 15 ~ 20 parts of ethanol, 3 ~ 6 parts of zinc oxide, 2 ~ 5 parts of titanium dioxide, 5 ~ 10 parts of OctMets, 4 ~ 7 parts of PAROSOL 1789s, 5 ~ 8 parts of 2-cyano group-3,3-diphenyl 2-Propenoic acid-2-ethylhexyl esters, 10 ~ 12 parts of vitamin Es, 20 ~ 30 parts of deionized waters, 8 ~ 12 parts of xanthan gum and 3 ~ 5 parts of span 20s after the solarization that 10 ~ 20 parts of step 7) are obtained;
9) Oleum Cocois, lanoline, span 20 and the vitamin E that will take, agitating heating 5 ~ 10min at 70 ~ 75 DEG C, obtains A phase; Wherein, the rotating speed of stirring is 250 ~ 350r/min;
10) ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789 and 2-cyano group-3, the 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester mix homogeneously that will take, supersound process 5 ~ 15min under room temperature, obtains B phase; Wherein, ultrasonic power is 250 ~ 400W;
11) deionized water taken and xanthan gum are heated 10 ~ 15min in 60 ~ 80 DEG C of stirred in water bath, obtain C phase; Wherein, speed of agitator is 250 ~ 300r/min;
12) under 50 ~ 60 DEG C of water bath condition, B is added in A phase and obtains mixed phase D, stir process 20 ~ 30min is carried out to mixed phase D; Wherein, speed of agitator is 350 ~ 450r/min;
13) be added to by C in the mixed phase D after step 12) process, stir 5 ~ 7min at 50 ~ 60 DEG C after, homogenizing 10 ~ 20min, obtains Emulsion Phase E; Wherein, speed of agitator is 300 ~ 400r/min, and homogenization pressure is 45 ~ 55MPa;
14) repair function microcapsule after the solarization taken is added in homogeneous phase E, stir 4 ~ 6min, obtain homogeneous phase F; Wherein, speed of agitator is 120 ~ 180r/min;
15) by homogeneous phase F through 18 ~ 20h ageing, obtain the described sunscreen cream containing repair function microcapsule after shining.
Compared to existing technology, the present invention has following beneficial effect:
1, the present invention adopts natural plant extracts to repair composition as after solarization, and found when employing 4 parts of vitamin Es, 3 parts of Radix Hamamelidis Mollis ethanol extract, 3 parts of Herba Portulacae ethanol extract, 4 parts of peoniflorins, 5 parts of green tea ethanol extract and 2 parts of Cys composite usages by research, the best of efficacy exertion is repaired after shining, effectively can alleviate the rubescent hot phenomenon that after shining, skin occurs, farthest to releive skin, the generation of the phenomenon that prevents from tanning severely.
2, the present invention will repair composition embedding by microcapsule technology after natural solarization, and the microcapsule after embedding is added in sunscreen cream, make the sunscreen cream obtained in use can play double effects that is sun-proof and that repair after shining simultaneously, just can the skin after solarization be repaired in the short time after solarization; And the sunscreen cream adopting this technology obtained, effectively prevent sun-prevention component and after shining, repair composition and coexist and the bad interactive competition phenomenon that causes, make this sunscreen cream effectively can ensure sun-proof function before use and after shining, repair effect to disappear or to decline, there is excellent performance.
3, the present invention have shine after to repair the microcapsule embedded property of effect good, the embedding rate of microcapsule is up to 97.12%, make can not be subject to the impact that in external environment, light, heat, oxygen etc. are too much in this microcapsule storage process, effectively ensure that the activity of active substance is not destroyed, the effect extending product keeps the phase.
4, microcapsule product shape of the present invention is regular, cyst wall has uniform thickness, and has uniform intensity, can retain the perfect shape of microcapsule and not be destroyed, the problem that capsule-core is revealed can not be caused, can not be damaged during effectively ensureing product stock, transport, shelf life.
5, sunscreen cream stable system of the present invention, the problem such as there will not be water separating of oil, not easy to apply, has stable character.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, in the present embodiment if no special instructions, raw materials used be commercially available.
Described Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract and green tea ethanol extract are after the ethanol water of employing 70% carries out alcohol extraction to Radix Hamamelidis Mollis, Herba Portulacae and green tea respectively, successively the extract that obtains of decompression recycling ethanol, lyophilization.
The preparation method of embodiment 1 one kinds containing the sunscreen cream of repair function microcapsule after solarization, comprises the steps:
1) microencapsulation material of following weight portion is taken: 20 portions of maltodextrins, 15 parts of arabic gums, 10 parts of hydroxyethyl-celluloses, 20 portions of Oleum Cocois, 5 parts of Oleum Hippophaes, 5 parts of Jojoba waxes, 3 parts of squalanes, 3 parts of vitamin Es, 2 parts of Radix Hamamelidis Mollis ethanol extract, 2 parts of Herba Portulacae ethanol extract, 1 part of peoniflorin, 2 parts of green tea ethanol extract, 1 part of Cys and 1 part of sorbester p17;
2) add in deionized water by the maltodextrin taken and arabic gum, heating for dissolving at 75 DEG C, is mixed with mixed solution A; Wherein, the volume of the deionized water added is 25 times of maltodextrin and arabic gum gross mass;
3) add the hydroxyethyl-cellulose weighed up in the mixed solution A prepared to step 1), after stirring, supersound process 1min at 75 DEG C, obtains capsule wall solution B; Wherein, hyperacoustic power is 400W;
4) Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract and the Cys mix homogeneously that will take, under the water bath condition of 60 DEG C after supersound process 5min, disperse 3min with high speed dispersor, obtain mixture C; Wherein the rotating speed of dispersion machine is 2000r/min;
5) in mixture C, add span, use homogenizer homogenizing 5min, obtain emulsifying homogeneous liquid D; Wherein homogenization pressure is 55MPa;
6) by after capsule wall solution B and emulsifying homogeneous liquid D mix homogeneously, after first using high speed dispersor dispersion 2min, then carry out homogenizing 2min, obtain mixed liquor E; Wherein, the rotating speed of high speed dispersor is 1500r/min, and homogenization pressure is 40MPa;
7) spraying dry is carried out to mixed liquor E, obtain shining rear repair function microcapsule; Wherein, controlling inlet temperature is 175 DEG C, and leaving air temp is 85 DEG C, feed rate 4.00mL/min;
8) the sunscreen cream raw material of following weight portion is taken: repair function microcapsule, 30 portions of Oleum Cocois, 15 parts of lanolines, 15 parts of ethanol, 3 parts of zinc oxide, 2 parts of titanium dioxide, 5 parts of OctMets, 4 parts of PAROSOL 1789s, 5 parts of 2-cyano group-3,3-diphenyl 2-Propenoic acid-2-ethylhexyl esters, 10 parts of vitamin Es, 20 parts of deionized waters, 8 parts of xanthan gum and 3 parts of span 20s after the solarization that 10 parts of step 7) are obtained;
9) Oleum Cocois, lanoline, span 20 and the vitamin E that will take, agitating heating 5min at 70 DEG C, obtains A phase; Wherein, the rotating speed of stirring is 250r/min;
10) ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789 and 2-cyano group-3, the 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester mix homogeneously that will take, supersound process 5min under room temperature, obtains B phase; Wherein, ultrasonic power is 250W;
11) deionized water taken and xanthan gum are heated 10min in 60 DEG C of stirred in water bath, obtain C phase; Wherein, speed of agitator is 250r/min;
12) under 50 DEG C of water bath condition, B is added in A phase and obtains mixed phase D, stir process 20min is carried out to mixed phase D; Wherein, speed of agitator is 350r/min;
13) be added to by C in the mixed phase D after step 12) process, stir 5min at 50 DEG C after, homogenizing 10min, obtains Emulsion Phase E; Wherein, speed of agitator is 300r/min, and homogenization pressure is 45MPa;
14) repair function microcapsule after the solarization taken is added in homogeneous phase E, stir 4min, obtain homogeneous phase F; Wherein, speed of agitator is 120r/min;
15) by homogeneous phase F through 18h ageing, obtain the described sunscreen cream containing repair function microcapsule after shining.
The preparation method of embodiment 2 one kinds containing the sunscreen cream of repair function microcapsule after solarization, comprises the steps:
1) microencapsulation material of following weight portion is taken: 30 portions of maltodextrins, 25 parts of arabic gums, 15 parts of hydroxyethyl-celluloses, 25 portions of Oleum Cocois, 15 parts of Oleum Hippophaes, 10 parts of Jojoba waxes, 5 parts of squalanes, 5 parts of vitamin Es, 4 parts of Radix Hamamelidis Mollis ethanol extract, 4 parts of Herba Portulacae ethanol extract, 5 parts of peoniflorins, 6 parts of green tea ethanol extract, 3 parts of Cys and 3 parts of sorbester p17s;
2) add in deionized water by the maltodextrin taken and arabic gum, heating for dissolving at 85 DEG C, is mixed with mixed solution A; Wherein, the volume of the deionized water added is 36 times of maltodextrin and arabic gum gross mass;
3) add the hydroxyethyl-cellulose weighed up in the mixed solution A prepared to step 1), after stirring, supersound process 4min at 85 DEG C, obtains capsule wall solution B; Wherein, hyperacoustic power is 550W;
4) Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract and the Cys mix homogeneously that will take, under the water bath condition of 80 DEG C after supersound process 10min, disperse 6min with high speed dispersor, obtain mixture C; Wherein the rotating speed of dispersion machine is 2500r/min;
5) in mixture C, add span, use homogenizer homogenizing 15min, obtain emulsifying homogeneous liquid D; Wherein homogenization pressure is 60MPa;
6) by after capsule wall solution B and emulsifying homogeneous liquid D mix homogeneously, after first using high speed dispersor dispersion 5min, then carry out homogenizing 7min, obtain mixed liquor E; Wherein, the rotating speed of high speed dispersor is 2000r/min, and homogenization pressure is 50MPa;
7) spraying dry is carried out to mixed liquor E, obtain shining rear repair function microcapsule; Wherein, controlling inlet temperature is 178 DEG C, and leaving air temp is 92 DEG C, feed rate 4.45mL/min;
8) the sunscreen cream raw material of following weight portion is taken: repair function microcapsule, 40 portions of Oleum Cocois, 20 parts of lanolines, 20 parts of ethanol, 6 parts of zinc oxide, 5 parts of titanium dioxide, 10 parts of OctMets, 7 parts of PAROSOL 1789s, 8 parts of 2-cyano group-3,3-diphenyl 2-Propenoic acid-2-ethylhexyl esters, 12 parts of vitamin Es, 30 parts of deionized waters, 12 parts of xanthan gum and 5 parts of span 20s after the solarization that 20 parts of step 7) are obtained;
9) Oleum Cocois, lanoline, span 20 and the vitamin E that will take, agitating heating 10min at 75 DEG C, obtains A phase; Wherein, the rotating speed of stirring is 350r/min;
10) ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789 and 2-cyano group-3, the 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester mix homogeneously that will take, supersound process 15min under room temperature, obtains B phase; Wherein, ultrasonic power is 400W;
11) deionized water taken and xanthan gum are heated 15min in 80 DEG C of stirred in water bath, obtain C phase; Wherein, speed of agitator is 300r/min;
12) under 60 DEG C of water bath condition, B is added in A phase and obtains mixed phase D, stir process 30min is carried out to mixed phase D; Wherein, speed of agitator is 450r/min;
13) be added to by C in the mixed phase D after step 12) process, stir 7min at 60 DEG C after, homogenizing 20min, obtains Emulsion Phase E; Wherein, speed of agitator is 400r/min, and homogenization pressure is 55MPa;
14) repair function microcapsule after the solarization taken is added in homogeneous phase E, stir 6min, obtain homogeneous phase F; Wherein, speed of agitator is 180r/min;
15) by homogeneous phase F through 20h ageing, obtain the described sunscreen cream containing repair function microcapsule after shining.
The preparation method of embodiment 3 one kinds containing the sunscreen cream of repair function microcapsule after solarization, comprises the steps:
1) microencapsulation material of following weight portion is taken: 25 portions of maltodextrins, 20 parts of arabic gums, 13 parts of hydroxyethyl-celluloses, 23 portions of Oleum Cocois, 10 parts of Oleum Hippophaes, 8 parts of Jojoba waxes, 4 parts of squalanes, 4 parts of vitamin Es, 3 parts of Radix Hamamelidis Mollis ethanol extract, 3 parts of Herba Portulacae ethanol extract, 4 parts of peoniflorins, 5 parts of green tea ethanol extract, 2 parts of Cys and 2 parts of sorbester p17s;
2) add in deionized water by the maltodextrin taken and arabic gum, heating for dissolving at 80 DEG C, is mixed with mixed solution A; Wherein, the volume of the deionized water added is 30 times of maltodextrin and arabic gum gross mass;
3) add the hydroxyethyl-cellulose weighed up in the mixed solution A prepared to step 1), after stirring, supersound process 3min at 80 DEG C, obtains capsule wall solution B; Wherein, hyperacoustic power is 500W;
4) Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract and the Cys mix homogeneously that will take, under the water bath condition of 70 DEG C after supersound process 8min, disperse 5min with high speed dispersor, obtain mixture C; Wherein the rotating speed of dispersion machine is 2200r/min;
5) in mixture C, add span, use homogenizer homogenizing 10min, obtain emulsifying homogeneous liquid D; Wherein homogenization pressure is 58MPa;
6) by after capsule wall solution B and emulsifying homogeneous liquid D mix homogeneously, after first using high speed dispersor dispersion 3min, then carry out homogenizing 5min, obtain mixed liquor E; Wherein, the rotating speed of high speed dispersor is 1800r/min, and homogenization pressure is 45MPa;
7) spraying dry is carried out to mixed liquor E, obtain shining rear repair function microcapsule; Wherein, controlling inlet temperature is 175 DEG C, and leaving air temp is 90 DEG C, feed rate 4.30mL/min;
8) the sunscreen cream raw material of following weight portion is taken: repair function microcapsule, 35 portions of Oleum Cocois, 18 parts of lanolines, 18 parts of ethanol, 5 parts of zinc oxide, 4 parts of titanium dioxide, 8 parts of OctMets, 6 parts of PAROSOL 1789s, 7 parts of 2-cyano group-3,3-diphenyl 2-Propenoic acid-2-ethylhexyl esters, 11 parts of vitamin Es, 25 parts of deionized waters, 10 parts of xanthan gum and 4 parts of span 20s after the solarization that 15 parts of step 7) are obtained;
9) Oleum Cocois, lanoline, span 20 and the vitamin E that will take, agitating heating 8min at 75 DEG C, obtains A phase; Wherein, the rotating speed of stirring is 300r/min;
10) ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789 and 2-cyano group-3, the 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester mix homogeneously that will take, supersound process 10min under room temperature, obtains B phase; Wherein, ultrasonic power is 300W;
11) deionized water taken and xanthan gum are heated 13min in 60 ~ 80 DEG C of stirred in water bath, obtain C phase; Wherein, speed of agitator is 280r/min;
12) under 55 DEG C of water bath condition, B is added in A phase and obtains mixed phase D, stir process 25min is carried out to mixed phase D; Wherein, speed of agitator is 400r/min;
13) be added to by C in the mixed phase D after step 12) process, stir 6min at 55 DEG C after, homogenizing 15min, obtains Emulsion Phase E; Wherein, speed of agitator is 350r/min, and homogenization pressure is 50MPa;
14) repair function microcapsule after the solarization taken is added in homogeneous phase E, stir 5min, obtain homogeneous phase F; Wherein, speed of agitator is 150r/min;
15) by homogeneous phase F through 19h ageing, obtain the described sunscreen cream containing repair function microcapsule after shining.
The embedding rate repairing the microcapsule of effect after shining above-mentioned obtained having is investigated, the microcapsule embedded rate that the microcapsule embedded rate that the microcapsule embedded rate that result display embodiment 1 obtains is 95.76%, embodiment 2 is obtained is 96.38%, embodiment 3 is obtained is 97.12%, has good embedding effect.
The present invention will repair composition embedding by microcapsule technology after natural solarization, and the microcapsule after embedding is added in sunscreen cream, make the sunscreen cream obtained in use can play double effects that is sun-proof and that repair after shining simultaneously, just can the skin after solarization be repaired in the short time after solarization; And the sunscreen cream adopting this technology obtained, effectively prevent sun-prevention component and after shining, repair composition and coexist and the bad interactive competition phenomenon that causes, make this sunscreen cream effectively can ensure sun-proof function before use and after shining, repair effect to disappear or to decline, there is excellent performance.
What finally illustrate is, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although applicant's reference preferred embodiment is to invention has been detailed description, those of ordinary skill in the art is to be understood that, technical scheme of the present invention is modified or equivalent replacement, and do not depart from the aim of technical solution of the present invention and scope, all should be encompassed in the middle of right of the present invention.
Claims (8)
1. the preparation method containing the sunscreen cream of repair function microcapsule after solarization, is characterized in that, comprise the steps:
1) microencapsulation material of following weight portion is taken: 20 ~ 30 portions of maltodextrins, 15 ~ 25 parts of arabic gums, 10 ~ 15 parts of hydroxyethyl-celluloses, 20 ~ 25 portions of Oleum Cocois, 5 ~ 15 parts of Oleum Hippophaes, 5 ~ 10 parts of Jojoba waxes, 3 ~ 5 parts of squalanes, 3 ~ 5 parts of vitamin Es, 2 ~ 4 parts of Radix Hamamelidis Mollis ethanol extract, 2 ~ 4 parts of Herba Portulacae ethanol extract, 1 ~ 5 part of peoniflorin, 2 ~ 6 parts of green tea ethanol extract, 1 ~ 3 part of Cys and 1 ~ 3 part of sorbester p17;
2) add in deionized water by the maltodextrin taken and arabic gum, heating for dissolving at 75 ~ 85 DEG C, is mixed with mixed solution A; Wherein, the volume of the deionized water added is 25 ~ 36 times of maltodextrin and arabic gum gross mass;
3) add the hydroxyethyl-cellulose weighed up in the mixed solution A prepared to step 1), after stirring, at 75 ~ 85 DEG C, supersound process 1 ~ 4min, obtains capsule wall solution B; Wherein, hyperacoustic power is 400 ~ 550W;
4) Oleum Cocois, Oleum Hippophae, Jojoba wax, squalane, vitamin E, Radix Hamamelidis Mollis ethanol extract, Herba Portulacae ethanol extract, peoniflorin, green tea ethanol extract and the Cys mix homogeneously that will take, under the water bath condition of 60 ~ 80 DEG C after supersound process 5 ~ 10min, with high speed dispersor dispersion 3 ~ 6min, obtain mixture C; Wherein the rotating speed of dispersion machine is 2000 ~ 2500r/min;
5) in mixture C, add span, use homogenizer homogenizing 5 ~ 15min, obtain emulsifying homogeneous liquid D; Wherein homogenization pressure is 55 ~ 60MPa;
6) by after capsule wall solution B and emulsifying homogeneous liquid D mix homogeneously, after first using high speed dispersor dispersion 2 ~ 5min, then carry out homogenizing 2 ~ 7min, obtain mixed liquor E; Wherein, the rotating speed of high speed dispersor is 1500 ~ 2000r/min, and homogenization pressure is 40 ~ 50MPa;
7) spraying dry is carried out to mixed liquor E, obtain shining rear repair function microcapsule; Wherein, controlling inlet temperature is 175 ~ 178 DEG C, and leaving air temp is 85 ~ 92 DEG C, feed rate 4.00 ~ 4.45mL/min;
8) the sunscreen cream raw material of following weight portion is taken: repair function microcapsule, 30 ~ 40 portions of Oleum Cocois, 15 ~ 20 parts of lanolines, 15 ~ 20 parts of ethanol, 3 ~ 6 parts of zinc oxide, 2 ~ 5 parts of titanium dioxide, 5 ~ 10 parts of OctMets, 4 ~ 7 parts of PAROSOL 1789s, 5 ~ 8 parts of 2-cyano group-3,3-diphenyl 2-Propenoic acid-2-ethylhexyl esters, 10 ~ 12 parts of vitamin Es, 20 ~ 30 parts of deionized waters, 8 ~ 12 parts of xanthan gum and 3 ~ 5 parts of span 20s after the solarization that 10 ~ 20 parts of step 7) are obtained;
9) Oleum Cocois, lanoline, span 20 and the vitamin E that will take, agitating heating 5 ~ 10min at 70 ~ 75 DEG C, obtains A phase; Wherein, the rotating speed of stirring is 250 ~ 350r/min;
10) ethanol, zinc oxide, titanium dioxide, OctMet, PAROSOL 1789 and 2-cyano group-3, the 3-diphenyl 2-Propenoic acid-2-ethylhexyl ester mix homogeneously that will take, supersound process 5 ~ 15min under room temperature, obtains B phase; Wherein, ultrasonic power is 250 ~ 400W;
11) deionized water taken and xanthan gum are heated 10 ~ 15min in 60 ~ 80 DEG C of stirred in water bath, obtain C phase; Wherein, speed of agitator is 250 ~ 300r/min;
12) under 50 ~ 60 DEG C of water bath condition, B is added in A phase and obtains mixed phase D, stir process 20 ~ 30min is carried out to mixed phase D; Wherein, speed of agitator is 350 ~ 450r/min;
13) be added to by C in the mixed phase D after step 12) process, stir 5 ~ 7min at 50 ~ 60 DEG C after, homogenizing 10 ~ 20min, obtains Emulsion Phase E; Wherein, speed of agitator is 300 ~ 400r/min, and homogenization pressure is 45 ~ 55MPa;
14) repair function microcapsule after the solarization taken is added in homogeneous phase E, stir 4 ~ 6min, obtain homogeneous phase F; Wherein, speed of agitator is 120 ~ 180r/min;
15) by homogeneous phase F through 18 ~ 20h ageing, obtain the described sunscreen cream containing repair function microcapsule after shining.
2. the preparation method of sunscreen cream according to claim 1 containing repair function microcapsule after shining, is characterized in that, step 2) in the volume of deionized water that adds be maltodextrin and arabic gum gross mass 30 times.
3. the preparation method of sunscreen cream according to claim 1 containing repair function microcapsule after shining, is characterized in that, in step 3) at 80 DEG C supersound process 3min.
4. the preparation method according to claim 1 containing the sunscreen cream of repair function microcapsule after solarization, it is characterized in that, in step 4), the rotating speed of dispersion machine is 2200r/min.
5. the preparation method according to claim 1 containing the sunscreen cream of repair function microcapsule after solarization, it is characterized in that, the rotating speed of step 6) high speed dispersion machine is 1800r/min, and homogenization pressure is 45MPa.
6. the preparation method according to claim 1 containing the sunscreen cream of repair function microcapsule after solarization, it is characterized in that, controlling inlet temperature in step 7) is 175 DEG C, and leaving air temp is 90 DEG C, feed rate 4.30mL/min.
7. the preparation method of sunscreen cream according to claim 1 containing repair function microcapsule after shining, is characterized in that, in step 10) under room temperature supersound process 10min, ultrasonic power is 300W.
8. the preparation method according to claim 1 containing the sunscreen cream of repair function microcapsule after solarization, it is characterized in that, in step 13), speed of agitator is 350r/min, and homogenization pressure is 50MPa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510735753.1A CN105213271B (en) | 2015-11-03 | 2015-11-03 | A kind of preparation method of the suncream containing after-sun function microcapsules |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510735753.1A CN105213271B (en) | 2015-11-03 | 2015-11-03 | A kind of preparation method of the suncream containing after-sun function microcapsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105213271A true CN105213271A (en) | 2016-01-06 |
| CN105213271B CN105213271B (en) | 2018-06-19 |
Family
ID=54982797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510735753.1A Active CN105213271B (en) | 2015-11-03 | 2015-11-03 | A kind of preparation method of the suncream containing after-sun function microcapsules |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105213271B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832611A (en) * | 2016-05-11 | 2016-08-10 | 广东科玮生物技术股份有限公司 | Natural plant extract composition and preparation method and application thereof |
| CN107308091A (en) * | 2017-06-29 | 2017-11-03 | 青岛海之星生物科技有限公司 | A kind of pure natural sunscreen cream and preparation method thereof |
| CN107440918A (en) * | 2017-08-15 | 2017-12-08 | 成都新柯力化工科技有限公司 | One kind can conjunctiva antiallergy sunscreen skin care item and preparation method |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3089392B1 (en) * | 2018-12-07 | 2021-12-31 | Oenotropic Innovation | USE OF A POLYSACCHARIDE AND A SULFUR COMPOUND FOR THE SUSPENSION OF PARTICLES IN A LIQUID COMPOSITION |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1287877A (en) * | 1999-07-27 | 2001-03-21 | 株式会社资生堂 | Micro-capsule and its prepn. method |
| JP2015054841A (en) * | 2013-09-12 | 2015-03-23 | 株式会社成和化成 | Oil-in-water type emulsion cosmetic |
| CN104906185A (en) * | 2015-05-26 | 2015-09-16 | 南京泽朗医药科技有限公司 | Chinese herbal medicine essential oil microcapsule and preparation method and application thereof |
-
2015
- 2015-11-03 CN CN201510735753.1A patent/CN105213271B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1287877A (en) * | 1999-07-27 | 2001-03-21 | 株式会社资生堂 | Micro-capsule and its prepn. method |
| JP2015054841A (en) * | 2013-09-12 | 2015-03-23 | 株式会社成和化成 | Oil-in-water type emulsion cosmetic |
| CN104906185A (en) * | 2015-05-26 | 2015-09-16 | 南京泽朗医药科技有限公司 | Chinese herbal medicine essential oil microcapsule and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 阎世翔: "《化妆品科学（下）》", 30 October 1998, 科学技术文献出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832611A (en) * | 2016-05-11 | 2016-08-10 | 广东科玮生物技术股份有限公司 | Natural plant extract composition and preparation method and application thereof |
| CN105832611B (en) * | 2016-05-11 | 2018-08-17 | 广东科玮生物技术股份有限公司 | A kind of natural plant extracts composition and its preparation method and application |
| CN107308091A (en) * | 2017-06-29 | 2017-11-03 | 青岛海之星生物科技有限公司 | A kind of pure natural sunscreen cream and preparation method thereof |
| CN107440918A (en) * | 2017-08-15 | 2017-12-08 | 成都新柯力化工科技有限公司 | One kind can conjunctiva antiallergy sunscreen skin care item and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105213271B (en) | 2018-06-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105213271A (en) | A kind of preparation method containing the sunscreen cream of repair function microcapsule after solarization | |
| CN101164528B (en) | Natural hair dyeing agent prepared by plant pigment catechu and hair dyeing method thereof | |
| CN104546516A (en) | Preparation process and application of compound ceramide liposome | |
| CN109674724B (en) | A kind of sleep mask and preparation method thereof containing dendrobium nobile | |
| CN107334686A (en) | Skin matrix, preparation method and applications and cosmetics and preparation method thereof | |
| CN103202788A (en) | Spot-fading cream taking persimmon leaf extract as functional raw material | |
| CN111773127A (en) | Cleansing oil based on natural vegetable oil and preparation steps thereof | |
| CN106135315A (en) | A kind of natural botanical insecticide | |
| CN106619186A (en) | Preparation for protecting activity of superoxide dismutase (SOD) and preparation method of preparation | |
| CN105213205A (en) | A kind of have the microcapsule shining rear reparation effect and the sunscreen cream containing this microcapsule | |
| CN101653409A (en) | Whitening and spot eliminating cream and preparation method thereof | |
| CN100415207C (en) | Sunscreen cream containing natural plant sunscreen component and its preparation method | |
| CN105687011A (en) | Fibroin facial cream | |
| CN103932954A (en) | Cosmetic for whitening and tendering skin and fining pores and preparation method thereof | |
| CN107362107A (en) | A kind of grass of strong skin hundred dew | |
| CN111939092A (en) | Skin refreshing and restoring emulsion for early-aged skin and preparation method and application thereof | |
| CN113730299B (en) | Preparation process of essential oil microcapsule containing essential oil | |
| CN105213203A (en) | A kind of preparation method of microcapsule-type moisturizing eye cream | |
| CN107582493B (en) | Dendrobium polysaccharide emulsion containing coconut oil and preparation method thereof | |
| CN110279598A (en) | A kind of whitening and spot eliminating cream preparation method | |
| WO2015078397A1 (en) | Chinese herbal medicine for repairing ultraviolet damage and promoting energy metabolism, and uses thereof in cosmetics | |
| CN105496852A (en) | Dendrobium nobile mask and preparation method thereof | |
| CN108815092A (en) | A kind of preparation method of the anti-acne maintenance Essence containing tea polyphenols | |
| CN104856894A (en) | Basil essential oil micro powder and preparation method therefor | |
| CN106214574A (en) | A kind of light speckle elite |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 401519 Chongqing Hechuan Industrial Park weir village two Patentee after: Chongqing Xiaowan Biotechnology Co., Ltd. Address before: 401519 Chongqing Hechuan Industrial Park weir village two Patentee before: CHONGQING XIAOWAN TRADE CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |