CN105209078B - 具有增强的不透射线性的聚合物组合物 - Google Patents

具有增强的不透射线性的聚合物组合物 Download PDF

Info

Publication number
CN105209078B
CN105209078B CN201480027781.1A CN201480027781A CN105209078B CN 105209078 B CN105209078 B CN 105209078B CN 201480027781 A CN201480027781 A CN 201480027781A CN 105209078 B CN105209078 B CN 105209078B
Authority
CN
China
Prior art keywords
group
formula
polymer
monomer
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201480027781.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN105209078A (zh
Inventor
S·D·古德里奇
J·P·卡斯尔伯里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Endoshape Inc
Original Assignee
Endoshape Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endoshape Inc filed Critical Endoshape Inc
Publication of CN105209078A publication Critical patent/CN105209078A/zh
Application granted granted Critical
Publication of CN105209078B publication Critical patent/CN105209078B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/22—Esters containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0442—Polymeric X-ray contrast-enhancing agent comprising a halogenated group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/041—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/18—Materials at least partially X-ray or laser opaque
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/18—Materials at least partially X-ray or laser opaque
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/303—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and one or more carboxylic moieties in the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/105—Esters of polyhydric alcohols or polyhydric phenols of pentaalcohols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Vascular Medicine (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201480027781.1A 2013-03-15 2014-03-14 具有增强的不透射线性的聚合物组合物 Expired - Fee Related CN105209078B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361787345P 2013-03-15 2013-03-15
US61/787,345 2013-03-15
PCT/US2014/028786 WO2014200594A1 (en) 2013-03-15 2014-03-14 Polymer compositions with enhanced radiopacity

Publications (2)

Publication Number Publication Date
CN105209078A CN105209078A (zh) 2015-12-30
CN105209078B true CN105209078B (zh) 2021-11-09

Family

ID=52022646

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480027781.1A Expired - Fee Related CN105209078B (zh) 2013-03-15 2014-03-14 具有增强的不透射线性的聚合物组合物

Country Status (7)

Country Link
US (1) US10590218B2 (enExample)
EP (1) EP2968620B1 (enExample)
JP (1) JP6543831B2 (enExample)
CN (1) CN105209078B (enExample)
AU (1) AU2014278745B2 (enExample)
CA (1) CA2903060A1 (enExample)
WO (1) WO2014200594A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2899309A1 (en) 2013-02-08 2014-08-14 Endoshape, Inc. Radiopaque polymers for medical devices
WO2014200594A1 (en) 2013-03-15 2014-12-18 Endoshape, Inc. Polymer compositions with enhanced radiopacity
WO2018053314A1 (en) 2016-09-16 2018-03-22 Greg Mirigian Occlusive implants with fiber-based release structures
WO2018102714A1 (en) 2016-12-02 2018-06-07 Endoshape, Inc. Radiopaque polymers with enhanced radiopacity
WO2019089479A1 (en) * 2017-10-30 2019-05-09 The Texas A&M University System Radiopaque thermoplastic polymer
CN113286549A (zh) 2019-06-05 2021-08-20 恩多沙普公司 用于改进的阻塞和递送的系统、装置和方法
EP4025616A4 (en) * 2019-09-12 2023-11-08 Endoshape, Inc. X-RAY DENSITY POLYMERS FOR MEDICAL DEVICES
CN114555659B (zh) * 2019-10-07 2024-09-20 法国加栢 不可降解的不透射线栓塞微球
KR102202101B1 (ko) * 2019-11-28 2021-01-14 주식회사 신아티앤씨 다관능 아크릴레이트 화합물, 이를 포함하는 양자점층 형성용 조성물 및 광학 필름
CN120423985B (zh) * 2025-07-02 2025-12-16 深圳市贝特瑞新能源技术研究院有限公司 一种多官能度单体及其制备方法、固态电解质、锂离子电池和涉电设备

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068969A (en) * 1998-01-23 2000-05-30 Fuji Photo Film Co., Ltd. Silver halide color photographic light-sensitive material and method for forming an image using the same
WO2008138974A2 (en) * 2007-05-15 2008-11-20 Occlutech Gmbh Occlusion instruments comprising bioresorbable radiopaque polymeric materials, as well as related products, methods and uses
US20090023827A1 (en) * 2005-11-28 2009-01-22 Andreas Lendlein Method of preparing shape memory materials starting from standard thermoplastic polymers
WO2012019145A1 (en) * 2010-08-06 2012-02-09 Endoshape, Inc. Radiopaque shape memory polymers for medical devices

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361700A (en) 1965-04-26 1968-01-02 Sterling Drug Inc Iodinated esters and resin compositions containing same
JPS52105006A (en) 1976-02-26 1977-09-03 Toyo Ink Mfg Co Composition of resin for hardenable film and printing ink
JPS57501430A (enExample) 1980-09-24 1982-08-12
JPS617314A (ja) * 1984-06-20 1986-01-14 Kureha Chem Ind Co Ltd 高屈折率レンズ
JPS621708A (ja) * 1985-06-28 1987-01-07 Showa Denko Kk 高屈折率樹脂用組成物
US5271923A (en) 1988-07-05 1993-12-21 Manac Incorporated Solid radiographic contrast medium
US5258020A (en) 1990-09-14 1993-11-02 Michael Froix Method of using expandable polymeric stent with memory
US5163952A (en) 1990-09-14 1992-11-17 Michael Froix Expandable polymeric stent with memory and delivery apparatus and method
US6248129B1 (en) 1990-09-14 2001-06-19 Quanam Medical Corporation Expandable polymeric stent with memory and delivery apparatus and method
US5964744A (en) 1993-01-04 1999-10-12 Menlo Care, Inc. Polymeric medical device systems having shape memory
US5599291A (en) 1993-01-04 1997-02-04 Menlo Care, Inc. Softening expanding ureteral stent
US5525327A (en) 1994-04-14 1996-06-11 Sterling Winthrop Inc. Polymeric x-ray contrast compositions containing iodinated polymeric beads and microcrystaline cellulose
DE4419386C2 (de) 1994-05-30 1996-09-19 Ivoclar Ag Röntgenopake Ester und Amide iodsubstituierter Benzoesäure sowie deren Verwendung zur Herstellung von Dentalmaterialien
EP0777503B1 (en) 1994-08-19 1999-11-17 Biomat B.V. Radiopaque polymers and methods for preparation thereof
GB9422008D0 (en) 1994-11-01 1994-12-21 London Hospital Med Coll High refractive index and/or radio-opaque resins systems
US5679710A (en) 1994-11-01 1997-10-21 London Hospital Medical College High refractive index and/or radio-opaque resins systems
CA2213403C (en) 1995-02-22 2007-01-16 Menlo Care, Inc. Covered expanding mesh stent
US5674242A (en) 1995-06-06 1997-10-07 Quanam Medical Corporation Endoprosthetic device with therapeutic compound
US6174330B1 (en) 1997-08-01 2001-01-16 Schneider (Usa) Inc Bioabsorbable marker having radiopaque constituents
CA2579619C (en) 1997-11-07 2012-01-03 Rutgers, The State University Radio-opaque polymeric biomaterials
AU751861B2 (en) 1998-02-23 2002-08-29 Massachusetts Institute Of Technology Biodegradable shape memory polymers
EP1062278B1 (en) 1998-02-23 2006-05-24 Mnemoscience GmbH Shape memory polymers
DE19857149A1 (de) 1998-12-11 2000-06-15 Bayer Ag Röntgenkontrastierbare Kunststoffmassen
US6530950B1 (en) 1999-01-12 2003-03-11 Quanam Medical Corporation Intraluminal stent having coaxial polymer member
JP2002182002A (ja) * 2000-12-11 2002-06-26 Seed Co Ltd 合成樹脂製レンズおよびその製造方法
US6550480B2 (en) 2001-01-31 2003-04-22 Numed/Tech Llc Lumen occluders made from thermodynamic materials
DE10208211A1 (de) 2002-02-26 2003-09-11 Mnemoscience Gmbh Polymere Netzwerke
US20040030062A1 (en) 2002-05-02 2004-02-12 Mather Patrick T. Castable shape memory polymers
US7040323B1 (en) 2002-08-08 2006-05-09 Tini Alloy Company Thin film intrauterine device
CA2501549C (en) 2002-10-11 2011-08-30 University Of Connecticut Blends of amorphous and semicrystalline polymers having shape memory properties
US7141061B2 (en) 2002-11-14 2006-11-28 Synecor, Llc Photocurable endoprosthesis system
EP1594475A1 (en) 2003-02-19 2005-11-16 Mnemoscience GmbH Self-expanding device for the gastrointestinal or urogenital area
JP2004342537A (ja) * 2003-05-19 2004-12-02 Nitto Denko Corp ゲル電解質とこれを用いる非水電解質電池
WO2006028431A1 (en) 2003-05-21 2006-03-16 Impres Medical, Inc. Intrauterine implant and methods of use
EP1673109B1 (en) 2003-09-25 2019-03-20 Rutgers, The State University of New Jersey Inherently radiopaque polymeric products for embolotherapy
US7377939B2 (en) 2003-11-19 2008-05-27 Synecor, Llc Highly convertible endolumenal prostheses and methods of manufacture
GB0410582D0 (en) 2004-05-12 2004-06-16 Vista Optics Ltd Compositions for use in the manufacture of lenses
US8703113B2 (en) 2004-07-08 2014-04-22 Reva Medical Inc. Side-chain crystallizable polymers for medical applications
JP5107706B2 (ja) 2004-07-08 2012-12-26 レヴァ メディカル、 インコーポレイテッド 医療用途向けの側鎖結晶性ポリマー
US20060034769A1 (en) 2004-08-13 2006-02-16 Rutgers, The State University Radiopaque polymeric stents
CN101014642B (zh) 2004-08-13 2010-04-21 雷瓦医药公司 用于多种应用的固有不透射线的可生物再吸收的聚合物
US20060036045A1 (en) 2004-08-16 2006-02-16 The Regents Of The University Of California Shape memory polymers
JP2006077200A (ja) * 2004-09-13 2006-03-23 Dainippon Ink & Chem Inc 活性エネルギー線硬化性組成物
US20060095134A1 (en) 2004-10-28 2006-05-04 Sdgi Holdings, Inc. Materials, devices and methods for implantation of transformable implants
CN101170966A (zh) 2005-04-01 2008-04-30 科罗拉多州立大学董事会 移植物固定装置和方法
WO2008051279A1 (en) 2006-03-24 2008-05-02 Biomerix Corp Self-expandable endovascular device for aneurysm occlusion
EP2007288A4 (en) 2006-03-30 2011-03-16 Univ Colorado Regents MEDICAL DEVICE OF FORMED MEMORY SYNTHESIS
CN101415449A (zh) 2006-04-06 2009-04-22 雷瓦医药公司 用于治疗血管动脉瘤的栓塞假体
JP2007279585A (ja) * 2006-04-11 2007-10-25 Fujifilm Corp 感光性組成物、並びに光記録媒体、光記録方法及び光記録装置
US7951194B2 (en) 2006-05-26 2011-05-31 Abbott Cardiovascular Sysetms Inc. Bioabsorbable stent with radiopaque coating
KR20090024242A (ko) 2006-06-06 2009-03-06 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 아이오딘화 중합체
US8507639B2 (en) 2006-09-11 2013-08-13 Boston Scientific Scimed, Inc. Radiopaque amide polymers and medical devices formed thereof
EP2125068A2 (en) 2006-10-31 2009-12-02 Universiteit Maastricht Homogeneous, intrinsic radiopaque embolic particles
US20080269874A1 (en) 2007-04-30 2008-10-30 Yunbing Wang Implantable medical devices fabricated from polymers with radiopaque groups
WO2009132070A2 (en) 2008-04-22 2009-10-29 The Regents Of The University Of Colorado, A Body Corporate Thiol-vinyl and thiol-yne systems for shape memory polymers
JP2010186979A (ja) * 2008-12-03 2010-08-26 Fujifilm Corp インプリント用硬化性組成物、パターン形成方法およびパターン
EP2401998A1 (en) * 2010-07-02 2012-01-04 3M Innovative Properties Company Dental composition, kit of parts and use thereof
CA2899309A1 (en) 2013-02-08 2014-08-14 Endoshape, Inc. Radiopaque polymers for medical devices
WO2014200594A1 (en) 2013-03-15 2014-12-18 Endoshape, Inc. Polymer compositions with enhanced radiopacity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6068969A (en) * 1998-01-23 2000-05-30 Fuji Photo Film Co., Ltd. Silver halide color photographic light-sensitive material and method for forming an image using the same
US20090023827A1 (en) * 2005-11-28 2009-01-22 Andreas Lendlein Method of preparing shape memory materials starting from standard thermoplastic polymers
WO2008138974A2 (en) * 2007-05-15 2008-11-20 Occlutech Gmbh Occlusion instruments comprising bioresorbable radiopaque polymeric materials, as well as related products, methods and uses
WO2012019145A1 (en) * 2010-08-06 2012-02-09 Endoshape, Inc. Radiopaque shape memory polymers for medical devices

Also Published As

Publication number Publication date
EP2968620A1 (en) 2016-01-20
WO2014200594A1 (en) 2014-12-18
EP2968620B1 (en) 2019-02-13
AU2014278745A1 (en) 2015-09-17
JP2016513750A (ja) 2016-05-16
US10590218B2 (en) 2020-03-17
JP6543831B2 (ja) 2019-07-17
EP2968620A4 (en) 2016-10-05
AU2014278745B2 (en) 2019-03-14
CN105209078A (zh) 2015-12-30
US20160024239A1 (en) 2016-01-28
CA2903060A1 (en) 2014-12-18

Similar Documents

Publication Publication Date Title
CN105209078B (zh) 具有增强的不透射线性的聚合物组合物
JP7025401B2 (ja) 医療機器のための放射線不透過性ポリマー
EP3482776B1 (en) Radiopaque shape memory polymers for medical devices
US20200054770A1 (en) Radiopaque polymers with enhanced radiopacity
WO2022056168A1 (en) Radiopaque polymers and medical devices with enhanced properties
EP4025616A1 (en) Radiopaque polymers for medical devices

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20211109

CF01 Termination of patent right due to non-payment of annual fee