CN105193666A - Waterless hand sanitizer and preparation method thereof - Google Patents
Waterless hand sanitizer and preparation method thereof Download PDFInfo
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- CN105193666A CN105193666A CN201510701742.1A CN201510701742A CN105193666A CN 105193666 A CN105193666 A CN 105193666A CN 201510701742 A CN201510701742 A CN 201510701742A CN 105193666 A CN105193666 A CN 105193666A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
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Abstract
The invention discloses a waterless hand sanitizer which is aerosol and contains a feed liquid and a propellant. The feed liquid comprises, by weight, 20-70 parts of water, 0.1-2 parts of hydroxyethyl cellulose, 0.1-2 parts of Sepigel, 0.01-0.5 part of triethanolamine, 10-80 parts of ethanol, 1-10 parts of propylene glycol, 0.1-10 parts of span-85, 0.1-10 parts of PEG-40 hydrogenated castor oil, 0.05-1 part of aloe extract, 0.01-1 part of dihydro-oat acyl o-aminobenzoic acid, 0.1-2 parts of Artemisiae Princeps Pamp extract, 0.01-0.8 part of parachlorometaxylenol and 0.01-0.5 part of essence. The propellant comprises, by weight, 15-50 parts of propane and 50-85 parts of butane. Mass ratio of the propellant to the feed liquid is (0.25-1.25):1. The waterless hand sanitizer can give out strong and everlasting flip-flop musical sound when being used, thus bringing joy to users. In addition, the waterless hand sanitizer can have an obvious effect of cooling palms of a user and gives an ice-cool and refreshing feeling to the user.
Description
Technical field
The present invention relates to a kind of handwashing liquid and preparation method thereof, especially a kind of disposable handwashing liquid and preparation method thereof.
Background technology
Advocate today of saving water resource, protection of the environment in the whole society, disposable handwashing liquid, while guarantee health of people, can be saved valuable water resource whenever and wherever possible, beautify our environment.Disposable handwashing liquid, without the need to using towel, water and soap etc., has use, easy to carry, Non-water washing, can clean the advantages such as both hands whenever and wherever possible, be therefore more and more subject to liking of people.
Existing disposable handwashing liquid, when extruding or spray, does not generally have sound or has very of short duration sound, interesting general.And not there is ice to feel well refrigerant cooling-down effect, particularly when using summer, skinfeel is bad.
Summary of the invention
Can send after the object of the invention is to provide for above-mentioned the deficiencies in the prior art part a kind of ejection stronger and lasting crack musical sound, interesting comparatively strong, there is ice to feel well the disposable handwashing liquid of refrigerant cooling-down effect.Meanwhile, present invention also offers the preparation method of described disposable handwashing liquid.
For achieving the above object, the technical scheme that the present invention takes is: a kind of disposable handwashing liquid, and described disposable handwashing liquid is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 20 ~ 70 parts, water, hydroxyethyl-cellulose 0.1 ~ 2 part, match Bick 3050.1 ~ 2 parts, triethanolamine 0.01 ~ 0.5 part, ethanol 10 ~ 80 parts, propylene glycol 1 ~ 10 part, sorbester p37 0.1 ~ 10 part, Cremophor RH40 0.1 ~ 10 part, Aloe extract 0.05 ~ 1 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.01 ~ 1 part, Artemisia princeps Pamp. leaf extract 0.1 ~ 2 part, parachlorometaxylenol 0.01 ~ 0.8 part, 0.01 ~ 0.5 part, essence;
Described propellant comprises the component of following weight portion: 15 ~ 50 parts, propane, butane 50 ~ 85 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=(0.25-1.25): 1.
Disposable handwashing liquid of the present invention, described specific feed liquid and propellant is adopted to be prepared from, by disposable handwashing liquid is prepared into aerosol, when disposable handwashing liquid sprays from aerosol container, owing to adopting thickening agent and the emulsifying agent of described particular combination and proportioning in described feed liquid, feed liquid reaches specific emulsifying effectiveness and viscosity, makes the disposable handwashing liquid sprayed can send stronger and lasting crack musical sound, brings enjoyment to the use of people.Be 5 ~ 20 decibels after the size background correction noise of described crack musical sound, the time of crack musical sound is 2 ~ 8 minutes.And the feed liquid of specific composition of the present invention, has salubrious ice-cold sensation during use, user centre of the palm temperature can be reduced by 3 ~ 9 DEG C, when especially summer uses, to the sensation that user is salubrious.
As the preferred implementation of disposable handwashing liquid of the present invention, described feed liquid comprises the component of following weight portion: 35 ~ 55 parts, water, hydroxyethyl-cellulose 0.3 ~ 1 part, match Bick 3050.3 ~ 1 parts, triethanolamine 0.05 ~ 0.2 part, ethanol 30 ~ 60 parts, propylene glycol 1.5 ~ 5 parts, sorbester p37 1 ~ 5 part, Cremophor RH40 0.2 ~ 3 part, Aloe extract 0.1 ~ 0.5 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.1 ~ 0.5 part, Artemisia princeps Pamp. leaf extract 0.1 ~ 0.5 part, parachlorometaxylenol 0.01 ~ 0.5 part, 0.05 ~ 0.2 part, essence.When described feed liquid contains the component of weight portion described above, crack musical sound when the disposable handwashing liquid of gained uses can reach 3 ~ 7 minutes, and the time reached both can not allow people feel not strong, can not bring again the sensation of confusion because of overlong time to people.The size of described crack musical sound is 10 ~ 15 decibels, both can not be too little imperceptible because of sound, again can not because of allowing user feel to disturb by making noise very much too loudly.Therefore, when described feed liquid selects the component of described preferred weight part, can be appropriate bring enjoyment to user, and can not confusion be caused.And described in the compositional selecting of described feed liquid during preferred proportioning, when described disposable handwashing liquid uses, can to the centre of the palm greenhouse cooling 4 ~ 7 DEG C of user, both clearly can not feel very little and not because of cooling, easily can not cause cold injury too much because of local cooling again, to feel well cooling sensation to the good ice of user.
As the preferred implementation of disposable handwashing liquid of the present invention, described feed liquid comprises the component of following weight portion: 52 parts, water, hydroxyethyl-cellulose 0.65 part, match Bick 3050.65 parts, triethanolamine 0.1 part, ethanol 40 parts, propylene glycol 2 parts, sorbester p37 2.0 parts, Cremophor RH40 0.4 part, Aloe extract 0.2 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.4 part, Artemisia princeps Pamp. leaf extract 0.4 part, parachlorometaxylenol 0.2 part, 0.1 part, essence.When described feed liquid contains the component of described weight portion, when the disposable handwashing liquid of gained uses, from crack the musical sound time after aerosol container ejection and size most suitable, the strongest to the enjoyment of people.And the feed liquid of this compositing formula, can be that the centre of the palm of user lowers the temperature 5 ~ 6 DEG C when gained handwashing liquid uses, ice cooling sensation of feeling well be most suitable.
As the preferred implementation of disposable handwashing liquid of the present invention, described propellant comprises the component of following weight portion: 20 ~ 40 parts, propane, butane 60 ~ 80 parts.Propane easily gasifies, and can provide very high pressure, will soon run away after ejection, if propane content is too high, crack the time can be very short, but propane content is too low, and cause product pressure very little, the situation of ejection and poor effect, may cannot not spray completely.Butane pressure is very little, and relatively difficult gasification, is ejected on hand, utilizes the temperature in the centre of the palm slowly to gasify, and butane content high crack the musical sound time is long, but pressure is less than normal, and butane content is low, and crack the musical sound time is short.Present inventor finds through large quantity research, when described propellant adopts the proportioning of above-mentioned weight portion, the disposable handwashing liquid finally made crack the musical sound time can reach interesting requirement, and the situation of ejection and effect better, emission rate can be more than or equal to 97%.
As the preferred implementation of disposable handwashing liquid of the present invention, described propellant comprises the component of following weight portion: 36 parts, propane, butane 64 parts.Present inventor finds after further research, when described propellant adopts described specific proportioning, obtained disposable handwashing liquid crack musical sound can better reach interesting requirement, and the situation of ejection and better effects if, and emission rate can be greater than 97%.
As the preferred implementation of disposable handwashing liquid of the present invention, the mass ratio of described propellant and feed liquid is: propellant: feed liquid=(0.4-0.8): 1.Present inventor finds through large quantity research, when the mass ratio of propellant and feed liquid is propellant: feed liquid=(0.4-0.8): when 1, when obtained disposable handwashing liquid uses, good ice can be brought to feel well cooling sensation to user, and ejection effect is better, emission rate is higher.
As the preferred implementation of disposable handwashing liquid of the present invention, the mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.6:1.Present inventor finds, when the mass ratio of described propellant and feed liquid is propellant: feed liquid=0.6:1, during obtained disposable handwashing liquid use, best ice can be brought to feel well cooling sensation to user, and crack music effect is good, the time is long.
As the preferred implementation of disposable handwashing liquid of the present invention, in described feed liquid, hydroxyethyl-cellulose is 1:1 with the mass ratio of match Bick 305; The mass ratio of described sorbester p37 and Cremophor RH40 is: sorbester p37: Cremophor RH40=(2 ~ 5): 1.When adopting the thickening agent of described particular combination proportioning in described feed liquid, and when adopting the emulsifying agent of described particular combination proportioning, better, can bring stronger and lasting crack musical sound to user, interest is better for the emulsifying effectiveness of final gained feed liquid and viscosity.
As the preferred implementation of disposable handwashing liquid of the present invention, the mass percentage of described ethanol in feed liquid is 30 ~ 60%.When described ethanol content is too high, easily cause skin defat, if but the content of ethanol is too low, the drying time of disposable handwashing liquid is longer, and therefore, present inventor gropes through lot of experiments, find when described ethanol is when the mass percentage of feed liquid is 30 ~ 60%, described disposable handwashing liquid is not easy to cause skin defat when using, and drying time when using is 10 ~ 45s, and resultant effect is better.
In disposable handwashing liquid of the present invention, the viscosity of feed liquid is 100 ~ 5000cps, preferably 200 ~ 2000cps, more preferably 400 ~ 1000cps.In disposable handwashing liquid of the present invention, the control of viscosity of sludge is extremely important.Present inventor finds through large quantity research, only has and controls in described specific scope by the viscosity of described feed liquid, propellant and feed liquid rapid mixing under the state of rocking just can be made even, obtain and well spray effect; And the stability of product can be improved, what crack music effect can be made to represent is better.
Present invention also offers the preparation method of disposable handwashing liquid described above, described preparation method comprises the following steps:
(1) preparation of feed liquid
(1) in water, add hydroxyethyl-cellulose, stir;
(2) add match Bick 305, be stirred to milky white uniform state;
(3) add triethanolamine, stir;
(4) add propylene glycol and part ethanol, be stirred to translucent uniform state, described part ethanol accounts for 70% of total ethanol weight;
(5) add sorbester p37 and Cremophor RH40, stir, obtain mixture one;
(6) separately get a container, then parachlorometaxylenol is dissolved in remainder ethanol, to colorless state, obtains mixture two;
(7) mixture two is joined in mixture one, and add Aloe extract, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid, Artemisia princeps Pamp. leaf extract, essence successively, after stirring, obtain feed liquid;
(2) preparation of propellant
Propane and butane are mixed to get mist, obtain propellant;
(3) fill
Feed liquid fill is entered into aerosol container, valve is put into aerosol container, sealing, is packaged into an entirety, then pours in aerosol container by propellant, be finally arranged on aerosol container by shower nozzle, obtain product by valve and aerosol container.
In the preparation method of disposable handwashing liquid described above, the preparation of described feed liquid adopts cold allotment of labor's skill, namely in feed liquid preparation process without the need to heating, so not only energy efficient, and produce more be simple and easy to perform.
In the disposable handwashing liquid that said method prepares, the emission rate of described aerosol is more than or equal to 97%, and ejection pressure is 0.2 ~ 0.7MPa, and be preferably 0.4 ~ 0.6MPa, pressure is excessive easily to set off an explosion, and safety is poor; Pressure is too small, and not exclusively, ejection effect is poor in handwashing liquid ejection.
Disposable handwashing liquid of the present invention, first rocks before using, and makes propellant and feed liquid rapid mixing in the process of rocking even, can obtain and spray effect preferably.
Disposable handwashing liquid of the present invention, coordinate with propellant by selecting the feed liquid of specific components content, make aerosol, the disposable handwashing liquid of gained in use, stronger and lasting crack musical sound can be sent, bring enjoyment to the use of people, and certain temperature can be reduced for the palm of user, bring ice to feel well refrigerant sensation to user, be especially applicable to using summer.Meanwhile, disposable handwashing liquid pH of the present invention is neutral, does not hinder hands, and after ejection, 10 ~ 45s is dry, and after dry, skin smooth is not tight, has clean, sterilization preferably and soothing effect.The preparation method of disposable handwashing liquid of the present invention, adopts specific charging sequence to be prepared from, and can prepare the aerosol of disposable handwashing liquid safely and fast, described method is cold allotment of labor's skill, without the need to heating, energy-conserving and environment-protective more, and also production is more simple and easy to perform.
Detailed description of the invention
For better the object, technical solutions and advantages of the present invention being described, below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 20 parts, water, hydroxyethyl-cellulose 2 parts, match Bick 3050.1 parts, triethanolamine 0.5 part, ethanol 80 parts, propylene glycol 1 part, sorbester p37 0.1 part, Cremophor RH40 0.1 part, Aloe extract 0.05 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 1 part, Artemisia princeps Pamp. leaf extract 0.1 part, parachlorometaxylenol 0.8 part, 0.01 part, essence;
Described propellant comprises the component of following weight portion: 15 parts, propane, butane 85 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.25:1.
In disposable handwashing liquid described in the present embodiment, described dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid has irritation and antipruritic effect, and described Artemisia princeps Pamp. leaf extract is natural antiseptic agent, has antiinflammatory, antianaphylactic effect simultaneously.In disposable handwashing liquid described in the present embodiment, contained each composition is existing material, all directly can be purchased from market.
Disposable handwashing liquid described in the present embodiment adopts following methods to be prepared from:
(1) preparation of feed liquid
(1) in water, add hydroxyethyl-cellulose, stir;
(2) add match Bick 305, be stirred to milky white uniform state;
(3) add triethanolamine, stir;
(4) add propylene glycol and part ethanol, be stirred to translucent uniform state, described part ethanol accounts for 70% of total ethanol weight;
(5) add sorbester p37 and Cremophor RH40, stir, obtain mixture one;
(6) separately get a container, then parachlorometaxylenol is dissolved in remainder ethanol, to colorless state, obtains mixture two;
(7) mixture two is joined in mixture one, and add Aloe extract, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid, Artemisia princeps Pamp. leaf extract, essence successively, after stirring, obtain feed liquid;
(2) preparation of propellant
Propane and butane are mixed to get mist, obtain propellant;
(3) fill
Feed liquid fill is entered into aerosol container, valve is put into aerosol container, sealing, is packaged into an entirety, then pours in aerosol container by propellant, be finally arranged on aerosol container by shower nozzle, obtain product by valve and aerosol container.
Embodiment 2
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 70 parts, water, hydroxyethyl-cellulose 0.1 part, match Bick 3052 parts, triethanolamine 0.01 part, ethanol 10 parts, propylene glycol 10 parts, sorbester p37 10 parts, Cremophor RH40 10 parts, Aloe extract 1 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.01 part, Artemisia princeps Pamp. leaf extract 2 parts, parachlorometaxylenol 0.01 part, 0.5 part, essence;
Described propellant comprises the component of following weight portion: 15 parts, propane, butane 50 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=1:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 3
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 35 parts, water, hydroxyethyl-cellulose 1 part, match Bick 3051 parts, triethanolamine 0.05 part, ethanol 60 parts, propylene glycol 5 parts, sorbester p37 1 part, Cremophor RH40 1.2 parts, Aloe extract 0.5 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.1 part, Artemisia princeps Pamp. leaf extract 0.5 part, parachlorometaxylenol 0.01 part, 0.2 part, essence;
Described propellant comprises the component of following weight portion: 50 parts, propane, butane 80 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.8:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 4
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 45 parts, water, hydroxyethyl-cellulose 0.5 part, match Bick 3050.5 parts, triethanolamine 0.15 part, ethanol 45 parts, propylene glycol 3 parts, sorbester p37 4 parts, Cremophor RH40 1.5 parts, Aloe extract 0.25 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.2 part, Artemisia princeps Pamp. leaf extract 0.3 part, parachlorometaxylenol 0.3 part, 0.15 part, essence;
Described propellant comprises the component of following weight portion: 36 parts, propane, butane 64 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.6:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 5
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 55 parts, water, hydroxyethyl-cellulose 0.3 part, match Bick 3050.3 parts, triethanolamine 0.2 part, ethanol 30 parts, propylene glycol 1.5 parts, sorbester p37 5 parts, Cremophor RH40 2.5 parts, Aloe extract 0.1 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.5 part, Artemisia princeps Pamp. leaf extract 0.1 part, parachlorometaxylenol 0.5 part, 0.05 part, essence;
Described propellant comprises the component of following weight portion: 20 parts, propane, butane 60 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.4:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 6
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 52 parts, water, hydroxyethyl-cellulose 0.65 part, match Bick 3050.65 parts, triethanolamine 0.1 part, ethanol 40 parts, propylene glycol 2 parts, sorbester p37 2 parts, Cremophor RH40 0.4 part, Aloe extract 0.2 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.4 part, Artemisia princeps Pamp. leaf extract 0.4 part, parachlorometaxylenol 0.2 part, 0.1 part, essence;
Described propellant comprises the component of following weight portion: 30 parts, propane, butane 50 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.5:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 7
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 40 parts, water, hydroxyethyl-cellulose 0.8 part, match Bick 3050.8 parts, triethanolamine 0.15 part, ethanol 50 parts, propylene glycol 4 parts, sorbester p37 3 parts, Cremophor RH40 1 part, Aloe extract 0.4 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.3 part, Artemisia princeps Pamp. leaf extract 0.2 part, parachlorometaxylenol 0.4 part, 0.1 part, essence;
Described propellant comprises the component of following weight portion: 40 parts, propane, butane 80 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.7:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Embodiment 8
A kind of embodiment of the disposable handwashing liquid of the present invention, disposable handwashing liquid described in the present embodiment is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 60 parts, water, hydroxyethyl-cellulose 1.5 parts, match Bick 3051.5 parts, triethanolamine 0.3 part, ethanol 20 parts, propylene glycol 8 parts, sorbester p37 9 parts, Cremophor RH40 6 parts, Aloe extract 0.8 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.7 part, Artemisia princeps Pamp. leaf extract 1.5 parts, parachlorometaxylenol 0.7 part, 0.4 part, essence;
Described propellant comprises the component of following weight portion: 45 parts, propane, butane 60 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=1.25:1.
The preparation method of disposable handwashing liquid described in the present embodiment is with embodiment 1.
Crack musical sound effect test when the disposable handwashing liquid of embodiment 9 the present invention uses
This test is divided into matched group and test group, and test group comprises test group 1 ~ 8, the disposable handwashing liquid that test group 1 ~ 8 adopts embodiment 1 ~ 8 to prepare respectively.Matched group adopts disposable handwashing liquid of the prior art, directly can be purchased from market.
Respectively the disposable handwashing liquid of matched group and test group is sprayed from aerosol container, whether the disposable handwashing liquid observed after ejection has crack musical sound, record the time that crack musical sound continues simultaneously, and the decibel of crack musical sound is detected with the sound decibel detector of specialty, the decibel of crack the musical sound of described detection is the result after background correction noise.Result of the test is in table 1.
Table 1 crack musical sound effects
| Group | Whether there is crack musical sound | Crack the musical sound persistent period | Crack musical sound decibel |
| Matched group | No | 0 minute | 0 decibel |
| Test group 1 | Be | 2 minutes | 5 decibels |
| Test group 2 | Be | 2 minutes | 8 decibels |
| Test group 3 | Be | 3 minutes | 10 decibels |
| Test group 4 | Be | 5 minutes | 12 decibels |
| Test group 5 | Be | 7 minutes | 15 decibels |
| Test group 6 | Be | 5 minutes | 11 decibels |
| Test group 7 | Be | 5 minutes | 13 decibels |
| Test group 8 | Be | 8 minutes | 20 decibels |
Present inventor is stochastic sampling 1000 people in use crowd, learnt by sensory experience's statistics, when the persistent period of crack musical sound be 2 ~ 8 minutes, crack musical sound be 5 ~ 20 decibels time, both can not be strong to people's sensation, again can not oversize because of the time, cause confusion too loudly.Particularly the persistent period of crack musical sound is 3 ~ 7 minutes, crack musical sound is when being 10 ~ 15 decibels, to the more suitable interest impression appropriately of people.Especially the persistent period of crack musical sound is 5 minutes, crack musical sound is when being 12 decibels, under the prerequisite not bringing confusion to user, to the interest that people is the strongest.
Test drying time when the disposable handwashing liquid of embodiment 10 the present invention uses
This test is divided into matched group and test group, and test group comprises test group 1 ~ 8, the disposable handwashing liquid that test group 1 ~ 8 adopts embodiment 1 ~ 8 to prepare respectively.Matched group adopts disposable handwashing liquid of the prior art, directly can be purchased from market.
Adopt the disposable handwashing liquid of matched group and test group to be sprayed on user palm respectively, disposable handwashing liquid is sprawled evenly smearing on hand by user, and start timing, until disposable handwashing liquid is all dry on hand, timing terminates.Calculate disposable handwashing liquid to sprawl evenly to all dry time from smearing, be drying time, result is as shown in table 2.
Table 2 result drying time
| Group | Drying time |
| Matched group | 30 seconds |
| Test group 1 | 10 seconds |
| Test group 2 | 45 seconds |
| Test group 3 | 15 seconds |
| Test group 4 | 18 seconds |
| Test group 5 | 20 seconds |
| Test group 6 | 19 seconds |
| Test group 7 | 16 seconds |
| Test group 8 | 35 seconds |
Present inventor finds through large quantity research, and drying time when described disposable handwashing liquid uses is that 10 ~ 45s is advisable, and preferably 15 ~ 20 seconds, most preferably 18 seconds, drying time was too short, and general ethanol content is too high, easily caused skin defat; Ethanol content very little, product can be made in use to occur a large amount of foam, affect skinfeel, also have a greatly reduced quality by crack music effect, and drying time also can be caused oversize simultaneously, consuming time longer when user uses, and uses inconvenience.
The disposable handwashing liquid ice of embodiment 11 the present invention feel well cooling sensation test
This test is divided into matched group and test group, and test group comprises test group 1 ~ 8, the disposable handwashing liquid that test group 1 ~ 8 adopts embodiment 1 ~ 8 to prepare respectively.Matched group adopts disposable handwashing liquid of the prior art, directly can be purchased from market.
Test comparison group and test group experimenter centre of the palm temperature, the i.e. initial centre of the palm temperature of experimenter respectively.Then the disposable handwashing liquid of matched group and test group is adopted to be sprayed on the user centre of the palm respectively, disposable handwashing liquid is smeared at palm and is sprawled evenly by user, until on hand after the whole drying of disposable handwashing liquid, the centre of the palm temperature of test subject again, centre of the palm temperature after namely using.The initial centre of the palm temperature of contrast experimenter and use rear centre of the palm temperature, draw the cooling size after the experimenter centre of the palm before use, result is as shown in table 3.
Table 3 cooling-down effect
| Group | Cooling size |
| Matched group | 0℃ |
| Test group 1 | 3℃ |
| Test group 2 | 8.5℃ |
| Test group 3 | 7℃ |
| Test group 4 | 5℃ |
| Test group 5 | 4℃ |
| Test group 6 | 5℃ |
| Test group 7 | 6℃ |
| Test group 8 | 9℃ |
Present inventor studies discovery by inquiry, when described disposable handwashing liquid uses, comparatively suitable to the centre of the palm cooling 3 ~ 9 DEG C of user, if cooling is not felt very little, does not possess ice and to feel well cooling sensation; If cooling is too many, easily cause cold injury.Especially to user centre of the palm cooling 4 ~ 7 DEG C, user can be experienced better ice and to feel well cooling sensation; And when the user centre of the palm is lowered the temperature 5 DEG C time, ensureing under the prerequisite that can not cause cold injury to user, to feel well cooling sensation to the best ice of user.
The bactericidal effect of the disposable handwashing liquid of embodiment 12 the present invention
Test is divided into test group 1 ~ 8, the disposable handwashing liquid that test group 1 ~ 8 adopts embodiment 1 ~ 8 to prepare respectively, test respectively and often organize disposable handwashing liquid to staphylococcus aureus, escherichia coli, the Candida albicans effect sterilizing rate of 2 minutes, result is as shown in table 4.
Table 4 bactericidal effect
| Group | Staphylococcus aureus | Escherichia coli | Candida albicans |
| Test group 1 | 99.99％ | 99.99％ | 99.99％ |
| Test group 2 | 96.72％ | 95.96％ | 96.05％ |
| Test group 3 | 97.86％ | 97.54％ | 97.08％ |
| Test group 4 | 99.05％ | 99.14％ | 99.19％ |
| Test group 5 | 99.95％ | 99.84％ | 99.87％ |
| Test group 6 | 98.76％ | 98.55％ | 98.27％ |
| Test group 7 | 99.54％ | 99.63％ | 99.71％ |
| Test group 8 | 99.98％ | 99.92％ | 99.96％ |
As seen from Table 4, disposable handwashing liquid of the present invention has good bactericidal effect.
Provable by above-described embodiment, when disposable handwashing liquid of the present invention uses, stronger and lasting crack musical sound can be sent, bring enjoyment to the use of people.When described handwashing liquid uses, obvious cooling-down effect can be played to the palm of user, feel well refrigerant sensation to user ice, be especially applicable to using summer.
Finally to should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention but not limiting the scope of the invention; although be explained in detail the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to technical scheme of the present invention or equivalent replacement, and not depart from essence and the scope of technical solution of the present invention.
Claims (10)
1. a disposable handwashing liquid, is characterized in that, described disposable handwashing liquid is aerosol, and described disposable handwashing liquid comprises feed liquid and propellant;
Described feed liquid comprises the component of following weight portion: 20 ~ 70 parts, water, hydroxyethyl-cellulose 0.1 ~ 2 part, match Bick 3050.1 ~ 2 parts, triethanolamine 0.01 ~ 0.5 part, ethanol 10 ~ 80 parts, propylene glycol 1 ~ 10 part, sorbester p37 0.1 ~ 10 part, Cremophor RH40 0.1 ~ 10 part, Aloe extract 0.05 ~ 1 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.01 ~ 1 part, Artemisia princeps Pamp. leaf extract 0.1 ~ 2 part, parachlorometaxylenol 0.01 ~ 0.8 part, 0.01 ~ 0.5 part, essence;
Described propellant comprises the component of following weight portion: 15 ~ 50 parts, propane, butane 50 ~ 85 parts;
The mass ratio of described propellant and feed liquid is: propellant: feed liquid=(0.25-1.25): 1.
2. disposable handwashing liquid as claimed in claim 1; it is characterized in that, described feed liquid comprises the component of following weight portion: 35 ~ 55 parts, water, hydroxyethyl-cellulose 0.3 ~ 1 part, match Bick 3050.3 ~ 1 parts, triethanolamine 0.05 ~ 0.2 part, ethanol 30 ~ 60 parts, propylene glycol 1.5 ~ 5 parts, sorbester p37 1 ~ 5 part, Cremophor RH40 0.2 ~ 3 part, Aloe extract 0.1 ~ 0.5 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.1 ~ 0.5 part, Artemisia princeps Pamp. leaf extract 0.1 ~ 0.5 part, parachlorometaxylenol 0.01 ~ 0.5 part, 0.05 ~ 0.2 part, essence.
3. disposable handwashing liquid as claimed in claim 2; it is characterized in that, described feed liquid comprises the component of following weight portion: 52 parts, water, hydroxyethyl-cellulose 0.65 part, match Bick 3050.65 parts, triethanolamine 0.1 part, ethanol 40 parts, propylene glycol 2 parts, sorbester p37 2.0 parts, Cremophor RH40 0.4 part, Aloe extract 0.2 part, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid 0.4 part, Artemisia princeps Pamp. leaf extract 0.4 part, parachlorometaxylenol 0.2 part, 0.1 part, essence.
4. the disposable handwashing liquid as described in claim 1 or 2 or 3, it is characterized in that, described propellant comprises the component of following weight portion: 20 ~ 40 parts, propane, butane 60 ~ 80 parts.
5. disposable handwashing liquid as claimed in claim 4, is characterized in that, described propellant comprises the component of following weight portion: 36 parts, propane, butane 64 parts.
6. disposable handwashing liquid as claimed in claim 1, is characterized in that, the mass ratio of described propellant and feed liquid is: propellant: feed liquid=(0.4-0.8): 1.
7. disposable handwashing liquid as claimed in claim 6, is characterized in that, the mass ratio of described propellant and feed liquid is: propellant: feed liquid=0.6:1.
8. disposable handwashing liquid as claimed in claim 1, is characterized in that, in described feed liquid, hydroxyethyl-cellulose is 1:1 with the mass ratio of match Bick 305; The mass ratio of described sorbester p37 and Cremophor RH40 is: sorbester p37: Cremophor RH40=(2 ~ 5): 1.
9. disposable handwashing liquid as claimed in claim 1, is characterized in that, the mass percentage of described ethanol in feed liquid is 30 ~ 60%.
10. the preparation method of disposable handwashing liquid as claimed in claim 1, is characterized in that, comprise the following steps:
(1) preparation of feed liquid
(1) in water, add hydroxyethyl-cellulose, stir;
(2) add match Bick 305, be stirred to milky white uniform state;
(3) add triethanolamine, stir;
(4) add propylene glycol and part ethanol, be stirred to translucent uniform state, described part ethanol accounts for 70% of total ethanol weight;
(5) add sorbester p37 and Cremophor RH40, stir, obtain mixture one;
(6) separately get a container, then parachlorometaxylenol is dissolved in remainder ethanol, to colorless state, obtains mixture two;
(7) mixture two is joined in mixture one, and add Aloe extract, dihydro Herba bromi japonici acyl group ortho-aminobenzoic acid, Artemisia princeps Pamp. leaf extract, essence successively, after stirring, obtain feed liquid;
(2) preparation of propellant
Propane and butane are mixed to get mist, obtain propellant;
(3) fill
Feed liquid fill is entered into aerosol container, valve is put into aerosol container, sealing, is packaged into an entirety, then pours in aerosol container by propellant, be finally arranged on aerosol container by shower nozzle, obtain product by valve and aerosol container.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106309273A (en) * | 2016-08-25 | 2017-01-11 | 攀柔莎（江苏）生物科技股份有限公司 | Skin care leave-in liquid soap |
| CN106511199A (en) * | 2016-11-30 | 2017-03-22 | 桂林理工大学 | Skincare no-clean hand-cleaning spray hand sanitizer and preparation method |
| CN107519084A (en) * | 2017-08-28 | 2017-12-29 | 清远市立道精细化工有限公司 | A kind of after-sun restorative mousse aerosol and preparation method thereof |
| CN107550818A (en) * | 2017-09-26 | 2018-01-09 | 广西达庆生物科技股份有限公司 | A kind of washing-free antibacterial liquid and preparation method thereof |
| CN108636101A (en) * | 2018-04-27 | 2018-10-12 | 广东自由能科技股份有限公司 | A kind of sterilizing deodoring agent and preparation method thereof and the application in aerosol |
| CN110664623A (en) * | 2019-11-18 | 2020-01-10 | 浙江绿岛科技有限公司 | Aerosol type alcohol-free wash-free antibacterial hand sanitizer and preparation method thereof |
| CN111743845A (en) * | 2020-07-17 | 2020-10-09 | 广州本心生物医药科技有限公司 | Traditional Chinese medicine extract no-clean hand sanitizer and preparation method thereof |
| CN113633578A (en) * | 2020-05-11 | 2021-11-12 | 中国热带农业科学院农产品加工研究所 | Artemisia princeps and galangal washing-free hand sanitizer and preparation method thereof |
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| CN106309273A (en) * | 2016-08-25 | 2017-01-11 | 攀柔莎（江苏）生物科技股份有限公司 | Skin care leave-in liquid soap |
| CN106511199A (en) * | 2016-11-30 | 2017-03-22 | 桂林理工大学 | Skincare no-clean hand-cleaning spray hand sanitizer and preparation method |
| CN107519084A (en) * | 2017-08-28 | 2017-12-29 | 清远市立道精细化工有限公司 | A kind of after-sun restorative mousse aerosol and preparation method thereof |
| CN107519084B (en) * | 2017-08-28 | 2020-04-21 | 清远市立道精细化工有限公司 | Aerosol for after-sun repair mousse and preparation method thereof |
| CN107550818A (en) * | 2017-09-26 | 2018-01-09 | 广西达庆生物科技股份有限公司 | A kind of washing-free antibacterial liquid and preparation method thereof |
| CN108636101A (en) * | 2018-04-27 | 2018-10-12 | 广东自由能科技股份有限公司 | A kind of sterilizing deodoring agent and preparation method thereof and the application in aerosol |
| CN110664623A (en) * | 2019-11-18 | 2020-01-10 | 浙江绿岛科技有限公司 | Aerosol type alcohol-free wash-free antibacterial hand sanitizer and preparation method thereof |
| WO2021098141A1 (en) * | 2019-11-18 | 2021-05-27 | 浙江绿岛科技有限公司 | Aerosol alcohol-free no-wash antibacterial hand sanitizer and preparation method therefor |
| CN113633578A (en) * | 2020-05-11 | 2021-11-12 | 中国热带农业科学院农产品加工研究所 | Artemisia princeps and galangal washing-free hand sanitizer and preparation method thereof |
| CN111743845A (en) * | 2020-07-17 | 2020-10-09 | 广州本心生物医药科技有限公司 | Traditional Chinese medicine extract no-clean hand sanitizer and preparation method thereof |
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