CN105188758A - 氟尼缩松的局部组合物及治疗方法 - Google Patents

氟尼缩松的局部组合物及治疗方法 Download PDF

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Publication number
CN105188758A
CN105188758A CN201480024925.8A CN201480024925A CN105188758A CN 105188758 A CN105188758 A CN 105188758A CN 201480024925 A CN201480024925 A CN 201480024925A CN 105188758 A CN105188758 A CN 105188758A
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CN
China
Prior art keywords
flunisolide
composition
topical
skin
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480024925.8A
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English (en)
Chinese (zh)
Inventor
道格拉斯·安东尼·巴肯
史蒂文·B·纽哈德
尼伦度·森
阿莫尔·苏巴什·曼德哈尔
图莎尔·迪奥莱姆·贾达尔
缪克斯·库玛尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicis Pharmaceutical Corp
Original Assignee
Medicis Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicis Pharmaceutical Corp filed Critical Medicis Pharmaceutical Corp
Publication of CN105188758A publication Critical patent/CN105188758A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480024925.8A 2013-03-15 2014-03-14 氟尼缩松的局部组合物及治疗方法 Pending CN105188758A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN303/KOL/2013 2013-03-15
IN303KO2013 2013-03-15
PCT/US2014/029722 WO2014145067A1 (en) 2013-03-15 2014-03-14 Topical compositions of flunisolide and methods of treatment

Publications (1)

Publication Number Publication Date
CN105188758A true CN105188758A (zh) 2015-12-23

Family

ID=54249680

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480024925.8A Pending CN105188758A (zh) 2013-03-15 2014-03-14 氟尼缩松的局部组合物及治疗方法

Country Status (7)

Country Link
US (1) US10953021B2 (enExample)
EP (1) EP2968572A1 (enExample)
JP (1) JP6473134B2 (enExample)
CN (1) CN105188758A (enExample)
AU (2) AU2014233362A1 (enExample)
CA (1) CA2905587A1 (enExample)
WO (1) WO2014145067A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938674A (zh) * 2017-05-27 2018-12-07 福建省山河药业有限公司 红色诺卡氏菌细胞壁骨架在制备治疗皮肤病变药物中的用途
CN110035755A (zh) * 2016-12-01 2019-07-19 玛路弘株式会社 医疗用皮肤外用剂
CN111670036A (zh) * 2018-01-31 2020-09-15 安成国际药业股份有限公司 包含托法替尼的局部调配物

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MX2007009796A (es) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
WO2011026076A2 (en) 2009-08-31 2011-03-03 Dr. Reddy's Laboratories Ltd. Topical formulations comprising a steroid
US20110268761A1 (en) 2010-03-02 2011-11-03 Hapten Pharmaceuticals, Llc Effective Sensitizing Dose of a Gelled Immunomodulating Topical Composition
MX2011007675A (es) 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
MX346763B (es) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
MX356551B (es) 2012-08-23 2018-06-04 Grupo Medifarma S A De C V Star Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné.
EA201691808A8 (ru) * 2014-03-11 2017-04-28 Промиус Фарма, Ллк Кортикостероидные композиции для местного применения
US20160184431A1 (en) 2014-03-11 2016-06-30 Promius Pharma Llc Topical compositions comprising a corticosteroid
WO2016026527A1 (en) * 2014-08-20 2016-02-25 Amantin Experts Compositions and methods for controlled moisturizing and release of active ingredients
CA2997949A1 (en) * 2015-09-11 2017-03-16 Rxi Pharmaceuticals Corporation Methods for treating skin disorders and conditions utilizing haptens
US10653656B2 (en) 2018-04-05 2020-05-19 Bausch Health Ireland Limited Topical pharmaceutical compositions for treating skin conditions
EP3586849A1 (en) * 2018-06-29 2020-01-01 Aprofol AG Folate preparations
MX368750B (es) * 2018-08-31 2019-10-15 Cell Therapy And Tech S A De C V Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.
AU2019403117B2 (en) 2018-12-18 2023-05-25 The Procter & Gamble Company Personal care composition with increased vapor release
AU2022346789A1 (en) * 2021-09-15 2024-03-28 Ocusoft, Inc. Ointments for treating dry skin
CN119997936A (zh) * 2022-12-15 2025-05-13 科笛生物医药(无锡)有限公司 羟基二苯乙烷类化合物软膏及其用途和制备方法
CN120500342A (zh) * 2022-12-20 2025-08-15 格林尼卡皮肤股份公司 用于局部皮肤治疗的新的组合物
WO2025182623A1 (ja) * 2024-02-28 2025-09-04 テクノガード株式会社 水および油難溶性薬物含有乳剤およびその製造方法

Citations (3)

* Cited by examiner, † Cited by third party
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US4333927A (en) * 1980-03-27 1982-06-08 Mitsubishi Chemical Industries, Ltd. Skin preparation
US20060246098A1 (en) * 2005-03-16 2006-11-02 Srinivasa Rao Stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same
US20110305643A1 (en) * 2010-06-11 2011-12-15 Precision Dermatology, Inc. High Oil-Content Emollient Aerosol Foam Compositions

Family Cites Families (13)

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US3126375A (en) 1964-03-24 Chioacyl
US4933168A (en) 1975-05-27 1990-06-12 Syntex Pharmaceuticals International Limited Stable, crystalline flunisolide
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
GB8420771D0 (en) 1984-08-15 1984-09-19 Efamol Ltd Treatment of skin disorders
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
IT1256061B (it) 1992-11-20 1995-11-23 Composizione terapeutica per uso rettale a base di flunisolide e/o deirelativi esteri per il trattamento di disordini intestinali a carattere infiammatorio
US5840277A (en) 1993-03-30 1998-11-24 Charlotte Hospital Authority Treatment of chronic pulmonary inflammation
US7887842B2 (en) * 2003-02-07 2011-02-15 Teikoku Pharma Usa, Inc. Methods of administering a dermatological agent to a subject
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
WO2006102004A2 (en) * 2005-03-16 2006-09-28 Taro Pharmaceuticals U.S.A., Inc. A stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same
WO2009100406A2 (en) * 2008-02-07 2009-08-13 Synta Pharmaceuticals Corp. Topical formulations for the treatment of psoriasis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4333927A (en) * 1980-03-27 1982-06-08 Mitsubishi Chemical Industries, Ltd. Skin preparation
US4427670A (en) * 1980-03-27 1984-01-24 Mitsubishi Chemical Industries Limited Skin preparation
US20060246098A1 (en) * 2005-03-16 2006-11-02 Srinivasa Rao Stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same
US20110305643A1 (en) * 2010-06-11 2011-12-15 Precision Dermatology, Inc. High Oil-Content Emollient Aerosol Foam Compositions

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110035755A (zh) * 2016-12-01 2019-07-19 玛路弘株式会社 医疗用皮肤外用剂
CN108938674A (zh) * 2017-05-27 2018-12-07 福建省山河药业有限公司 红色诺卡氏菌细胞壁骨架在制备治疗皮肤病变药物中的用途
CN111670036A (zh) * 2018-01-31 2020-09-15 安成国际药业股份有限公司 包含托法替尼的局部调配物

Also Published As

Publication number Publication date
CA2905587A1 (en) 2014-09-18
AU2014233362A1 (en) 2015-10-01
JP2016515525A (ja) 2016-05-30
US10953021B2 (en) 2021-03-23
JP6473134B2 (ja) 2019-02-20
WO2014145067A1 (en) 2014-09-18
US20140274982A1 (en) 2014-09-18
AU2019200064A1 (en) 2019-01-24
EP2968572A1 (en) 2016-01-20

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PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20151223

WD01 Invention patent application deemed withdrawn after publication