JP6473134B2 - フルニソリドの局所用組成物および治療方法 - Google Patents

フルニソリドの局所用組成物および治療方法 Download PDF

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Publication number
JP6473134B2
JP6473134B2 JP2016503206A JP2016503206A JP6473134B2 JP 6473134 B2 JP6473134 B2 JP 6473134B2 JP 2016503206 A JP2016503206 A JP 2016503206A JP 2016503206 A JP2016503206 A JP 2016503206A JP 6473134 B2 JP6473134 B2 JP 6473134B2
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composition
flunisolide
topical
skin
amount
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Expired - Fee Related
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JP2016503206A
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Japanese (ja)
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JP2016515525A (ja
JP2016515525A5 (enExample
Inventor
ダグラス アンソニー ベイカン
ダグラス アンソニー ベイカン
スティーヴン ビー. ニューハード
スティーヴン ビー. ニューハード
ニレンドゥ セン
ニレンドゥ セン
アモル サバシュ マンダレ
アモル サバシュ マンダレ
トュシャール デオラム ジャハブ
トュシャール デオラム ジャハブ
ムケーシュ クマル
ムケーシュ クマル
Original Assignee
メディシス ファーマシューティカル コーポレイション
メディシス ファーマシューティカル コーポレイション
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Publication of JP2016515525A publication Critical patent/JP2016515525A/ja
Publication of JP2016515525A5 publication Critical patent/JP2016515525A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016503206A 2013-03-15 2014-03-14 フルニソリドの局所用組成物および治療方法 Expired - Fee Related JP6473134B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN303/KOL/2013 2013-03-15
IN303KO2013 2013-03-15
PCT/US2014/029722 WO2014145067A1 (en) 2013-03-15 2014-03-14 Topical compositions of flunisolide and methods of treatment

Publications (3)

Publication Number Publication Date
JP2016515525A JP2016515525A (ja) 2016-05-30
JP2016515525A5 JP2016515525A5 (enExample) 2017-04-20
JP6473134B2 true JP6473134B2 (ja) 2019-02-20

Family

ID=54249680

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016503206A Expired - Fee Related JP6473134B2 (ja) 2013-03-15 2014-03-14 フルニソリドの局所用組成物および治療方法

Country Status (7)

Country Link
US (1) US10953021B2 (enExample)
EP (1) EP2968572A1 (enExample)
JP (1) JP6473134B2 (enExample)
CN (1) CN105188758A (enExample)
AU (2) AU2014233362A1 (enExample)
CA (1) CA2905587A1 (enExample)
WO (1) WO2014145067A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007009796A (es) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel conteniendo pirfenidona.
WO2011026076A2 (en) 2009-08-31 2011-03-03 Dr. Reddy's Laboratories Ltd. Topical formulations comprising a steroid
US20110268761A1 (en) 2010-03-02 2011-11-03 Hapten Pharmaceuticals, Llc Effective Sensitizing Dose of a Gelled Immunomodulating Topical Composition
MX2011007675A (es) 2011-07-19 2012-07-11 Cell Therapy And Technology S A De C V Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas.
MX346763B (es) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné.
MX356551B (es) 2012-08-23 2018-06-04 Grupo Medifarma S A De C V Star Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné.
EA201691808A8 (ru) * 2014-03-11 2017-04-28 Промиус Фарма, Ллк Кортикостероидные композиции для местного применения
US20160184431A1 (en) 2014-03-11 2016-06-30 Promius Pharma Llc Topical compositions comprising a corticosteroid
WO2016026527A1 (en) * 2014-08-20 2016-02-25 Amantin Experts Compositions and methods for controlled moisturizing and release of active ingredients
CA2997949A1 (en) * 2015-09-11 2017-03-16 Rxi Pharmaceuticals Corporation Methods for treating skin disorders and conditions utilizing haptens
WO2018101443A1 (ja) * 2016-12-01 2018-06-07 マルホ株式会社 医療用皮膚外用剤
CN108938674A (zh) * 2017-05-27 2018-12-07 福建省山河药业有限公司 红色诺卡氏菌细胞壁骨架在制备治疗皮肤病变药物中的用途
JP7324210B2 (ja) * 2018-01-31 2023-08-09 ティダブリューアイ・バイオテクノロジー・インコーポレイテッド トファシチニブを含む局所製剤
US10653656B2 (en) 2018-04-05 2020-05-19 Bausch Health Ireland Limited Topical pharmaceutical compositions for treating skin conditions
EP3586849A1 (en) * 2018-06-29 2020-01-01 Aprofol AG Folate preparations
MX368750B (es) * 2018-08-31 2019-10-15 Cell Therapy And Tech S A De C V Composiciones farmaceuticas semisolidas de base oleosa conteniendo pirfenidona para su aplicacion en la reparacion tisular.
AU2019403117B2 (en) 2018-12-18 2023-05-25 The Procter & Gamble Company Personal care composition with increased vapor release
AU2022346789A1 (en) * 2021-09-15 2024-03-28 Ocusoft, Inc. Ointments for treating dry skin
CN119997936A (zh) * 2022-12-15 2025-05-13 科笛生物医药(无锡)有限公司 羟基二苯乙烷类化合物软膏及其用途和制备方法
CN120500342A (zh) * 2022-12-20 2025-08-15 格林尼卡皮肤股份公司 用于局部皮肤治疗的新的组合物
WO2025182623A1 (ja) * 2024-02-28 2025-09-04 テクノガード株式会社 水および油難溶性薬物含有乳剤およびその製造方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126375A (en) 1964-03-24 Chioacyl
US4933168A (en) 1975-05-27 1990-06-12 Syntex Pharmaceuticals International Limited Stable, crystalline flunisolide
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
JPS56135416A (en) * 1980-03-27 1981-10-22 Mitsubishi Chem Ind Ltd Pharmaceutical preparation for skin
GB8420771D0 (en) 1984-08-15 1984-09-19 Efamol Ltd Treatment of skin disorders
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
IT1256061B (it) 1992-11-20 1995-11-23 Composizione terapeutica per uso rettale a base di flunisolide e/o deirelativi esteri per il trattamento di disordini intestinali a carattere infiammatorio
US5840277A (en) 1993-03-30 1998-11-24 Charlotte Hospital Authority Treatment of chronic pulmonary inflammation
US7887842B2 (en) * 2003-02-07 2011-02-15 Teikoku Pharma Usa, Inc. Methods of administering a dermatological agent to a subject
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
US20070020299A1 (en) * 2003-12-31 2007-01-25 Pipkin James D Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
WO2006102004A2 (en) * 2005-03-16 2006-09-28 Taro Pharmaceuticals U.S.A., Inc. A stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same
US20060246098A1 (en) * 2005-03-16 2006-11-02 Srinivasa Rao Stable aqueous-based emulsion formulation comprising urea and salicylic acid and method of using same
WO2009100406A2 (en) * 2008-02-07 2009-08-13 Synta Pharmaceuticals Corp. Topical formulations for the treatment of psoriasis
WO2011156030A2 (en) * 2010-06-11 2011-12-15 Precision Dermatology, Inc. High oil-content emollient aerosol foam compositions

Also Published As

Publication number Publication date
CA2905587A1 (en) 2014-09-18
AU2014233362A1 (en) 2015-10-01
JP2016515525A (ja) 2016-05-30
CN105188758A (zh) 2015-12-23
US10953021B2 (en) 2021-03-23
WO2014145067A1 (en) 2014-09-18
US20140274982A1 (en) 2014-09-18
AU2019200064A1 (en) 2019-01-24
EP2968572A1 (en) 2016-01-20

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