CN105169463A - Cationic baby medical dressing and preparation method thereof - Google Patents

Cationic baby medical dressing and preparation method thereof Download PDF

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Publication number
CN105169463A
CN105169463A CN201510529264.0A CN201510529264A CN105169463A CN 105169463 A CN105169463 A CN 105169463A CN 201510529264 A CN201510529264 A CN 201510529264A CN 105169463 A CN105169463 A CN 105169463A
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skin
purified water
medical dressing
ceramide
coenzyme
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CN201510529264.0A
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CN105169463B (en
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梁奕福
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DONGGUAN DAQING MEDICAL DEVICES Co.,Ltd.
GUANGXI DAQING BIOLOGICAL SCIENCE & TECHNOLOGY Co.,Ltd.
GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co.,Ltd.
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Guangxi Daqing Biotechnology Co Ltd
GUANGXI XINYE BIOLOGICAL TECHNOLOGY Co Ltd
Dongguan Da Qing Medical Devices Co Ltd
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Abstract

The invention relates to a cationic baby medical dressing and a preparation method thereof. The medical dressing is composed of the following raw materials in percent by weight: 0.8%-1.8% of chitosan quaternary ammonium salt, 0.1%-0.2% of polyhexamethyleneguanidine, 0.2%-0.7% of coenzyme Q10, 0.1%-0.6% of ceramide, 0.05%-0.2% of olive oil, 0.06%-0.2% of apricot kernel oil, 0.008%-0.012% of a skin restoration factor, 8%-15% of glycerin, and 0.2%-0.4% of peppermint oil, and the balance purified water. The medical dressing is applicable to perform disinfection sterilization processing on skin, possesses efficacies of moistening and restoring skin, enables a wound to be rapidly healed without leaving a scar, is widely applicable to infant red buttock, miliaria, varicella, napkin rash, eczema, urticaria, scabies, herpes and other skin diseases, and possesses good treatment effect on skin scratch, wound, scald, fire burn, mosquito bites and the like.

Description

A kind of cation baby medical dressing and preparation method thereof
Technical field
The present invention relates to infant skin nursing technique field, particularly relate to a kind of cation baby medical dressing and preparation method thereof.
Background technology
In the developmental process of people, the self-protection ability of baby is the most weak, is very easy to be subject to extraneous injury, as mosquito bite, burn and scald etc., easily suffers the infection of antibacterial, fungus and virus, therefore need to nurse wound site in wound site.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, a kind of cation baby medical dressing and preparation method thereof is provided, can nurses the wound site of baby, to the isolation of antibacterial, fungus, virus.
For achieving the above object, the technical solution used in the present invention is:
A kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 0.8% ~ 1.8%
Polyhexamethylene guanidine 0.1% ~ 0.2%
Coenzyme Q10 0.2% ~ 0.7%
Ceramide 0.1% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.008% ~ 0.012%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Purified water surplus.
Water instant cation chitosan quaternary ammonium salt has the performances such as good antibiotic property, film property, cation-adsorption, moisture absorbability and moisture retentivity, flocculability, antistatic behaviour.Its anti-microbial property is better than chitosan and other chitosan derivatives.After chitosan quaternary ammonium salt is water-soluble, ionize, containing a large amount of level Four ammonium cations in solution.Ammonium cation has certain fragmentation effect to antibacterial, fungus, virus.
Secondly polyhexamethylene guanidine, has broad-spectrum; Valid density is low; Speed of action is fast; Stable in properties; Premium properties soluble in water; Can use at normal temperatures; For a long time antibacterial, have no side effect; Polyhexamethylene guanidine is polyguanidine family macromolecule polymer, ionization can be produced in aqueous, its hydrophilic group part contains strong electropositive, absorption is usually in electronegative each bacterioid, virus, enter cell membrane, suppress the synthesis of film lactone plastid, cause thalline apoptosis, reach best bactericidal effect.
Chitosan quaternary ammonium salt, polyhexamethylene guanidine produce and form cation, can kill antibacterial, fungus and virus and isolate.
Glycerol, namely glycerol is without the sweet clear and bright thick liquid of color and taste, odorless; There is warm sweet taste.Glycerol can moisture content in draw air to skin moisture-keeping, also the moisture content in skin can be pinned, not allow it run off.There is effect of moisturizing.Moisturizing, moist effect can be played to the skin of baby.
Olive oil has beauty and skin care effect: olive oil is rich in the Squalene splendid with skin affinity and essential fatty acid, absorbs rapidly, effectively keeps skin elasticity with moist; Monounsaturated fatty acid contained abundant in olive oil and vitamin E, K, A, D etc. and phenols antioxidant, facial wrinkles can be eliminated, prevent skin aging, there is the effect such as skin or hair care and control hand and foot from chapping, be the cosmetics and skincare product that can " eat ", smear skin energy ultraviolet rays resistance with olive oil in addition and prevent skin carcinoma.In the numerous composition of olive oil, carotene and chlorophyll give olive oil yellow green, and chlorophyll plays metabolism, Promote cell's growth, accelerating wound healing.
Almond oil, the trace element of rich in proteins, unsaturated fatty acid, vitamin, inorganic salt, dietary fiber and needed by human body, has lung moistening, stomach invigorating, the effect that regains one's strength of body, the anti-cancer active matter that its amygdalin is natural especially.Also containing vitamin E, wherein based on alpha tocopherol and gama tocopherol.Therefore this oil is planted and is not only had very excellent Nutrition but also have good antioxidative stabilizer.Almond oil at home and abroad cosmetic applications very extensive, cream frost, milk are sweet, fancy soap all does natural additive with it.It adds skin moistening and anti-aging effects for product, also for product adds warm fragrance.Almond oil rich in mineral substances, protein and various vitamin, be the splendid vegetable oil of a kind of skin care and moisturizing effect, be applicable to various skin quality.It effectively can alleviate the skin people and to itch phenomenon, eliminates red and swollen, dry and inflammation.The sagging gland of the brain of hormonal system, thymus and adrenal gland can be stimulated, promote cell turnover.
The skin repair factor, has repair to skin.The microenvironment of Growth of Cells can be improved, promote the synthesis of elastic fiber and collagen protein, make skin high resilience, make skin be in sliding tender state.
Coenzyme Q10 coenzyme Q10 is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy, there is functions such as improving body immunity, enhancing antioxidation, slow down aging and enhancing human activity, medically be widely used in cardiovascular system diseases, extensively use it for nutrient and healthcare products and food additive both at home and abroad.Coenzyme Q10 (CoenzymeQ10), also known as ubiquinone (Ubiquinone, abbreviation UQ), is that one is present in natural fat-soluble quinones, and its structure and vitamin K, vitamin E are similar to plastoquinone.In human body cell, participate in energy manufacture and activation, be that prevention of arterial sclerosis forms the most effective antioxidation composition.Ubiquinone is present in most eukaryotic cell, especially mitochondrion.It is one of respiratory chain component; Its content on mitochondrial inner membrane is far away higher than the content of other components of respiratory chain, and the fat-soluble mobility making it have height on inner membrance, is particularly suitable as a kind of electron transit mediator of flowing.
Coenzyme Q10 mainly contains two effects in vivo, and one is be converted in the process of energy at nutrient substance to play an important role in mitochondrion, and two is have obvious lipoid peroxidization resistant.It is the power conversion agent in cell mitochondrial, and it produces ATP(adenosine triphosphate by shifting and transmit electronics participation " tricarboxylic acid cycle "), namely energy factors is for cellular metabolism.Coenzyme Q10 is effective antioxidant and free radical scavenger, it is embedded in mitochondrial inner membrane lipid bilayer as the ingredient of mitochondrial respiratory chain, alcohol of formula is become after 2 electronics that Mitochondria complex I or complex II accepts, then by electron transmission to complex III.Body coenzyme Q 10 is become alcohol of formula by a large amount of consumption, and it is effective antioxidant, and be also the electron carrier of motion, hydrogen atom is given to lipid peroxidation free radical from its hydroxyl by it simultaneously, thus reduces the lipid peroxide reaction of mitochondrial inner membrane.Generate the out-of-proportion free radical ubisemiquinone of alcohol of formula with coenzyme Q10 and coenzyme Q10 in the process, or to react formation superoxides with oxygen, free radical ubisemiquinone is transported free radical and is realized Detoxication under superoxide dismutase and catalatic effect, the respiratory chain that so moves in circles, by continuous for coenzyme Q10 regeneration alcohol of formula, has recovered its antioxidant activity effect.
Oleum menthae, skin that is unclean, that block can be nursed one's health, its refrigerant sensation, can blood capillary be shunk, releive itch, inflammation and burning, also can soft skin, also effect is had for removing blackhead and oiliness skin quality.
Oleum menthae has inhibitory action to herpes simplex virus, forest virus, mumps virus, has bacteriostasis to staphylococcus aureus, Staphylococcus albus, alpha streptococcus, group B streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax bacillus, diphtheria corynebacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli etc.; Water solublity Oleum menthae can excite nerve tip cold receptor and produce creeping chill, and reflexive cause the change of deep tissue blood vessel and play antiinflammatory, pain relieving, antipruritic effect.
Ceramide, also known as sphingolipid, is a kind of lipid being present in skin, plays an important role in epidermal keratinocytes layer formation process., when drying, desquamation, cracking phenomena appear in skin, when its barrier function obviously reduces, skin supplements ceramide can recover rapidly moisturizing and barrier function.
Cause xerosis cutis main cause to be that in horny layer of epidermis, ceramide content reduces, ceramide content height is directly related with skin dryness.Use ceramide can obviously strengthen adhesion strength between keratinocyte, improve skin dryness, reduce desquamation phenomenon.Ceramide has very strong associated water molecule ability, and it maintains moisture of skin by forming network structure in horny layer.Therefore, ceramide has the effect of maintenance moisture of skin.Use ceramide that ceramide content in horny layer of epidermis can be made to increase, xerosis cutis, desquamation, the situation such as coarse can be improved; Ceramide can increase epidermal keratinocytes layer thickness simultaneously, improves skin moisture holding capacity, reduces wrinkle, strengthens skin elasticity, delay skin aging.
Ceramide is a kind of water-soluble grease metallic substance, and it is close with the structure of matter forming keratodermatitis, can penetrate into skin very soon, and the water in horny layer combines, and forms a kind of network structure, pins moisture.
When the skin small size of infant is by traumatic infection, arm as red in infant, mosquito bite, burn and scald, miliaria, chickenpox, diaper rash, eczema, urticaria, scabies etc.Because the skin of infant is tenderer, self-repairing capability is more weak, after being subject to wound, and easy scar.Therefore infant skin site of injury, repair skin, in reparation, its effect main is the skin repair factor, promotes the synthesis of elastic fiber and collagen protein, while repairing skin, for avoiding the mode of appearance difference newly tying the skin histology formed larger; Adopt the combination of olive oil and almond oil to enter to smear to skin trauma place, the skin limit of wound can be made to enclose and keep moist and elasticity, the skin histology of new growth can not be divided because of hydropenia, chromogenesis; Form cicatrix.Antibody in infants is less, is easily infected, therefore disinfection after being subject to wound, adopts the combination of chitosan quaternary ammonium salt, polyhexamethylene guanidine in the technical program, because the bactericidal properties of polyhexamethylene guanidine is comparatively strong, and has certain toxicity; Therefore, the content of polyhexamethylene guanidine is lower, and preferably, chitosan quaternary ammonium salt content is greater than 7 times of polyhexamethylene guanidine content, and polyhexamethylene guanidine content is no more than 0.2%.In skin repair process, need skin moisture-keeping and moisten, avoiding water loss; Glycerol is adopted to carry out moisturizing and moisten in the technical program.The content of glycerol is preferably not less than 8%.After skin is subject to wound, some dead bark tissues may block the pore of neoplastic skin tissue, need to remove it; Synkaingenesis skin histology can produce certain pain and gargalesthesia; Adopt Oleum menthae to clear up skin, certain pain relieving, antipruritic effect can be played simultaneously.The composition of skin mainly has oils and fats, and after wound, the oil fraction of skin corium can expose to air, is vulnerable to oxidation stain; Coenzyme Q10 effectively can play antioxidant effect.Secondly, ceramide can play certain antiallergic, keep the effect of moisture of skin, makes neoplastic skin tissue effectively can keep moisture, avoids drying, pigementation.
Preferably, the content summation of chitosan quaternary ammonium salt and polyhexamethylene guanidine is no more than 1.95%.These two kinds of compositions, while sterilization, may hurt the leukocyte in Skin Cell and skin histology; By clinical trial analysis, when its weight is more than a timing, leukocyte work can be had influence on.
Preferably, a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.5%
Olive oil 0.08% ~ 0.12%
Almond oil 0.07% ~ 0.12%
The skin repair factor 0.009% ~ 0.01%
Glycerol 9% ~ 12%
Oleum menthae 0.2% ~ 0.4%
Purified water surplus.
Again preferably, a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.5%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Almond oil 0.1%
The skin repair factor 0.01%
Glycerol 10%
Oleum menthae 0.3%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Preferably, a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Purified water surplus.
Aloin can help to discharge dirt in body, purifies the blood, vessel softening, reduces blood pressure and blood viscosity, blood circulation promoting; The mixture of active component based on barbaloin is dicotyledon Aloe extract.Bactericidal action, antiinflammatory action, moistening beautification function, lets out effect under stomach invigorating, the heart tonifying effect of invigorating blood circulation, immunity and regeneration, immunity and antitumor action, Detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.The polysaccharide contained in Aloe and multivitamin have good nutrition, moist, whitening effect to human body skin.Aloe Barbadensis Miller is the Fresh leaf of aloe that optimum is directly improved looks, i.e. Aloe vulgaris, and it has the performance making skin contraction, softnessization, moisturizing, antiinflammatory, bleaching.Remove sclerosis, keratinization in addition, improve the effect of scar, little wrinkle, eye pouch, cutis laxa can not only be prevented, skin wet, tender and lovely can also be kept, simultaneously, can also scytitis be treated, also have good curative effect to acne, freckle, acne and scald, knife injury, insect bite etc.Effective too to hair, hair can be made to keep moistening smooth, pre-Anti-hair loss.
When the skin of infant is subject to wound, sometimes along with hemorrhage; Especially scald, also can along with inflammation; In dressing, increase a certain amount of aloin, certain haemostatic effect and antibacterial, antiinflammatory can be played; By clinical trial, do not conflict with other drug composition.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Further preferably, a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Hydrogen peroxide 1% ~ 2%
Purified water surplus.
Hydrogen peroxide has good oxidation effectiveness, when adopting the wound of the hydrogen peroxide of low concentration (especially weight ratio is lower than 3%) and skin, pus or dirt to meet, decomposes immediately and generates oxygen.This oxygen atom being not yet combined into oxygen molecule, has very strong oxidability, when contacting with antibacterial, can destroy microorganism, kill antibacterial.Can provide an aerobic environment, the collagen protein killing anaerobe and aid in skin is formed simultaneously.Here the content of hydrogen peroxide refers to: the weight content of hydrogen peroxide in whole dressing: 1% ~ 2%.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Because content 100% hydrogen peroxide is difficult to obtain, the hydrogen peroxide of the quality such as the hydrogen peroxide employing in step one, other concentration hydrogen peroxide substitute; I.e. step one, join get hydrogen peroxide time, other concentration hydrogen peroxide getting equivalent can being joined, getting 30% hydrogen peroxide (quality containing hydrogen peroxide is equal) of equal size hydrogen peroxide as joined; Step 2 replaces with: the purified water taking surplus.
Beneficial effect of the present invention is:
1), adopt chitosan quaternary ammonium salt, polyhexamethylene guanidine etc. to have bactericidal effect to skin trauma position, avoid subinfection again;
2), adopt glycerol, olive oil, Semen Armeniacae Amarum wet goods can maintain skin trauma position, avoid skin to lose moisture from wound site.
3), secondly, adopt and repair composition, skin is repaired, avoids occurring cicatrix.
Fast skin reparation can be reached, and do not leave scar.The treating skin diseases such as infant diaper dermatitis, miliaria, chickenpox, diaper rash, eczema, urticaria, scabies, herpes can be widely used in; Also good therapeutical effect is had to skin, scratch, wound, scald, burn, mosquito bite etc.
Detailed description of the invention
Below the present invention is described further.
Embodiment 1: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 0.8%
Polyhexamethylene guanidine 0.1%
Coenzyme Q10 0.7%
Ceramide 0.6%
Olive oil 0.05%
Almond oil 0.2%
The skin repair factor 0.008%
Glycerol 15%
Oleum menthae 0.4%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 1:
Huang, man, 11 months, when creeping, arm was scalded by cigarette end, and wound has suppuration, after wound cleaning, smeared the cation baby medical dressing one week of the present embodiment, every day 3 times; Wound healing, and without scar.
Embodiment 2: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.8%
Polyhexamethylene guanidine 0.1%
Coenzyme Q10 0.2%
Ceramide 0.1%
Olive oil 0.2%
Almond oil 0.05%
The skin repair factor 0.012%
Glycerol 8%
Oleum menthae 0.2%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 2
Zhang, female, 10 months, accidentally drops and overturns boiled water and be burned; Arm is got blister; After treatment of wounds, the cation baby medical dressing of coating the present embodiment 3 days, wound takes a turn for the better; New skin tissue growth, and scar is very light; Continue use 2 weeks, wound healing, without scar.
Embodiment 3: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.4%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.4%
Ceramide 0.4%
Olive oil 0.15%
Almond oil 0.12%
The skin repair factor 0.009%
Glycerol 13%
Oleum menthae 0.25%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 3
Lin, man, 1 years old, long chickenpox with it, there is cicatrix in chickenpox surrounding skin; The cation baby medical dressing of coating the present embodiment one week, cicatrix starts abatement; Continue use 3 weeks, cicatrix disappears.
Embodiment 4: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.7%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Almond oil 0.1%
The skin repair factor 0.01%
Glycerol 10%
Oleum menthae 0.3%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 4:
Lee, man, 5 months, suffers from diaper rash; Skin starts to have ulcer sign and with inflammation; After affected part cleaning, the cation baby medical dressing of film the present embodiment one week, inflammation starts abatement, new skin tissue growth; Cure after 4 weeks.
Embodiment 5: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.1%
Polyhexamethylene guanidine 0.15%
Coenzyme Q10 0.3%
Ceramide 0.6%
Olive oil 0.2%
Almond oil 0.06%
The skin repair factor 0.01%
Glycerol 8%
Oleum menthae 0.4%
Aloin 0.8%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 5
Zhang, man, 1.5 years old, suffers from scabies; Skin is scratched, pruritus, and has pigment to start precipitation; Use the cation baby medical dressing of the present embodiment after one week, pruritus disappear gradually or weaken, pigment removal; After 4 weeks, scabies starts the healing that scabs.
Embodiment 6: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.7%
Polyhexamethylene guanidine 0.17%
Coenzyme Q10 0.6%
Ceramide 0.2%
Olive oil 0.05%
Almond oil 0.2%
The skin repair factor 0.01%
Glycerol 15%
Oleum menthae 0.2%
Aloin 1%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 6
Lin, man, 2 years old, suffers from eczema; Skin is scratched, pruritus, and has inflammation; Use the cation baby medical dressing of the present embodiment after one week, pruritus disappear gradually or weaken, inflammation slows down; After 4 weeks, start the healing that scabs.
Embodiment 7: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.6%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Almond oil 0.1%
The skin repair factor 0.01%
Glycerol 10%
Oleum menthae 0.3%
Aloin 1%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Case 7
Field, female, 1 years old, suffers from eczema; Skin is scratched, pruritus, and occurs red point; Use the cation baby medical dressing of the present embodiment after one hour, pruritus disappears gradually or weakens; After 6 hours, red point disappears.
Embodiment 8: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.1%
Polyhexamethylene guanidine 0.15%
Coenzyme Q10 0.6%
Ceramide 0.2%
Olive oil 0.05%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerol 8%
Oleum menthae 0.4%
Aloin 0.8%
Hydrogen peroxide 1%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Because content 100% hydrogen peroxide is difficult to obtain, the hydrogen peroxide of the quality such as the hydrogen peroxide employing in step one, other concentration hydrogen peroxide substitute; I.e. step one, join get hydrogen peroxide time, other concentration hydrogen peroxide getting equivalent can being joined, getting 30% hydrogen peroxide (quality containing hydrogen peroxide is equal) of equal size hydrogen peroxide as joined; Step 2 replaces with: the purified water taking surplus.
Case 8: Zhang, female, 2 years old, is burned, and epidermis has ulcer, blister; After wound cleaning, smear the cation baby medical dressing of the present embodiment, wound scabs, and after one week, wound starts healing, new skin tissue growth, and pigementation appears in wound perimeter; After 4 weeks, wound healing; Pigment disappears; Without cicatrix.
Embodiment 9:
A kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.7%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.3%
Ceramide 0.6%
Olive oil 0.2%
Almond oil 0.06%
The skin repair factor 0.01%
Glycerol 15%
Oleum menthae 0.2%
Aloin 1%
Hydrogen peroxide 2%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Because content 100% hydrogen peroxide is difficult to obtain, the hydrogen peroxide of the quality such as the hydrogen peroxide employing in step one, other concentration hydrogen peroxide substitute; I.e. step one, join get hydrogen peroxide time, other concentration hydrogen peroxide getting equivalent can being joined, getting 30% hydrogen peroxide (quality containing hydrogen peroxide is equal) of equal size hydrogen peroxide as joined; Step 2 replaces with: the purified water taking surplus.
Case 9: close certain, man, 3 years old, falls down skin and be scratched, and part wound is darker; After wound cleaning, the cation baby medical dressing of coating the present embodiment, wound starts to scab, healing after a week; Without Infective morbidity; And without cicatrix.
Embodiment 10: a kind of cation baby medical dressing, is made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.5%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Almond oil 0.1%
The skin repair factor 0.01%
Glycerol 10%
Oleum menthae 0.3%
Aloin 1%
Hydrogen peroxide 1.5%
Purified water surplus.
A preparation method for above-mentioned cation baby medical dressing, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
Because content 100% hydrogen peroxide is difficult to obtain, the hydrogen peroxide of the quality such as the hydrogen peroxide employing in step one, other concentration hydrogen peroxide substitute; I.e. step one, join get hydrogen peroxide time, other concentration hydrogen peroxide getting equivalent can being joined, getting 30% hydrogen peroxide (quality containing hydrogen peroxide is equal) of equal size hydrogen peroxide as joined; Step 2 replaces with: the purified water taking surplus.
Case 10: Zhang, man, 1 years old, suffers from herpes; There is ulcer local; The cation baby medical dressing of coating the present embodiment, ulcer wound starts to scab, and after 3 days, herpes starts to eliminate; And without cicatrix.
Below be only the preferred embodiment of the application, equivalent technical solutions on this basis still falls into application protection domain.

Claims (8)

1. a cation baby medical dressing, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 0.8% ~ 1.8%
Polyhexamethylene guanidine 0.1% ~ 0.2%
Coenzyme Q10 0.2% ~ 0.7%
Ceramide 0.1% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.008% ~ 0.012%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Purified water surplus.
2. a kind of cation baby medical dressing according to claim 1, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.5%
Olive oil 0.08% ~ 0.12%
Almond oil 0.07% ~ 0.12%
The skin repair factor 0.009% ~ 0.01%
Glycerol 9% ~ 12%
Oleum menthae 0.2% ~ 0.4%
Purified water surplus.
3. a kind of cation baby medical dressing according to claim 1, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.5%
Polyhexamethylene guanidine 0.2%
Coenzyme Q10 0.5%
Ceramide 0.3%
Olive oil 0.1%
Almond oil 0.1%
The skin repair factor 0.01%
Glycerol 10%
Oleum menthae 0.3%
Purified water surplus.
4. a cation baby medical dressing, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Purified water surplus.
5. a cation baby medical dressing, is characterized in that: be made up of following raw material (weight ratio):
Chitosan quaternary ammonium salt 1.0% ~ 1.8%
Polyhexamethylene guanidine 0.15% ~ 0.2%
Coenzyme Q10 0.3% ~ 0.6%
Ceramide 0.2% ~ 0.6%
Olive oil 0.05% ~ 0.2%
Almond oil 0.06% ~ 0.2%
The skin repair factor 0.01%
Glycerol 8% ~ 15%
Oleum menthae 0.2% ~ 0.4%
Aloin 0.8% ~ 1%
Hydrogen peroxide 1% ~ 2%
Purified water surplus.
6. a preparation method for the arbitrary described cation baby medical dressing of claims 1 to 3, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
7. a preparation method for cation baby medical dressing according to claim 4, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
8. a preparation method for cation baby medical dressing according to claim 5, comprising:
Step one, the chitosan quaternary ammonium salt taking formula ratio, polyhexamethylene guanidine, coenzyme Q10, ceramide, olive oil, almond oil, the skin repair factor, glycerol, Oleum menthae, aloin, hydrogen peroxide;
Step 2, take the purified water of formula ratio;
Step 3, pours purified water mixing successively into by the formula of step one.
CN201510529264.0A 2015-08-26 2015-08-26 A kind of cation baby's medical dressing and preparation method thereof Active CN105169463B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812378A (en) * 2019-11-25 2020-02-21 湖南易兴建筑有限公司 Quaternary ammonium salt ozone oil and preparation method thereof
CN114504636A (en) * 2022-01-27 2022-05-17 华南理工大学 Almond oil scald ointment and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008400A (en) * 2010-11-24 2011-04-13 华中科技大学 Coenzyme Q10 nanolipid composition, and preparation method and application thereof
CN102335451A (en) * 2011-09-15 2012-02-01 德州海利安生物科技股份有限公司 Medical colloid dressing with functions for inhibiting bacteria and promoting heal and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008400A (en) * 2010-11-24 2011-04-13 华中科技大学 Coenzyme Q10 nanolipid composition, and preparation method and application thereof
CN102335451A (en) * 2011-09-15 2012-02-01 德州海利安生物科技股份有限公司 Medical colloid dressing with functions for inhibiting bacteria and promoting heal and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812378A (en) * 2019-11-25 2020-02-21 湖南易兴建筑有限公司 Quaternary ammonium salt ozone oil and preparation method thereof
CN114504636A (en) * 2022-01-27 2022-05-17 华南理工大学 Almond oil scald ointment and preparation method and application thereof
CN114504636B (en) * 2022-01-27 2023-09-26 华南理工大学 Almond oil scald ointment and preparation method and application thereof

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